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N

Nicolas R. Barthélemy

Washington University in St. Louis
H指数:37
被引数:6,740

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荣誉奖项

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Spatiotemporal characterization of Alzheimer disease pathology in living human brain tissue

活体人脑组织中阿尔茨海默病病理的时空表征

Nature Communications
IF15.7
2026-09-240
OAAI
Aram Aslanyan; Soumya Mukherjee; Eleanor M. Moncur; Alicja Szadziewska; Yingxin He; Przemysław R. Kac; Reid Coyle; Elena Camporesi; Chihiro Sato; Nupur Ghoshal; Nicolas R. Barthélemy; Jack Wood; Junyue Ge; Maciej Dulewicz; Srinivas Koutarapu; Katherine Schwetye; Kaleigh F. Roberts; Eimear C. Murphy; Francesco Carletti; Kaj Blennow; Fernando Gonzalez Ortiz; Claire A. Leckey; Tatiana A. Giovannucci; Kanza Tariq; Henrik Zetterberg; Donald L. Elbert; Lewis Thorne; Ahmed K. Toma; Laurence Watkins; Nick C. Fox; Randall J. Bateman; Jörg Hanrieder; Ross W. Paterson
Distribution of Big Tau Isoforms in the Human Central and Peripheral Nervous System

人类中枢和外周神经系统中的大分子量tau异构体分布

Annals of Neurology
IF7.7
2026-07-290
OAAI
Rama Krishna Koppisetti MSc; Nicolas R. Barthélemy PhD; Kanta Horie PhD; Cindy V. Ly PhD; Kaleigh F. Roberts PhD; Srinivas Koutarapu PhD; Richard J. Perrin PhD; Erin E. Franklin MS; Chiara Pedicone PhD; Joshua Orrick BS; Justin Melendez PhD; Timothy M. Miller MD, PhD; Chihiro Sato PhD; Nupur Ghoshal MD, PhD; Alison M. Goate PhD; Celeste M. Karch PhD; Randall J. Bateman MD; Soumya Mukherjee PhD
Trajectories of plasma and CSF MTBR-tau243 and phosphorylated-tau species across the Alzheimer’s disease continuum

血浆和脑脊液中MTBR-tau243及磷酸化-tau蛋白物种在阿尔茨海默病连续谱中的轨迹

Nature Communications
IF15.7
2026-04-090
OAAI
Lyduine E. Collij; Gemma Salvadó; Kanta Horie; Nicolas R. Barthélemy; Tobey J. Betthauser; Olof Strandberg; Ruben Smith; Sebastian Palmqvist; Suzanne E. Schindler; Rik Ossenkoppele; Shorena Janelidze; Niklas Mattsson-Carlgren; Randall J. Bateman; Oskar Hansson
Plasma levels of an N‐terminal tau fragment predict Alzheimer's and neurodegenerative disease biomarkers in autosomal dominant Alzheimer's disease

N端tau片段的血浆水平可预测常染色体显性遗传性阿尔茨海默病中的阿尔茨海默病及神经退行性疾病生物标志物

Alzheimers & Dementia
IF11.1
2026-01-080
OA
Stephanie A. Schultz; Yiwen Rao; Lei Liu; Beth Ostaszewski; Amirah K. Anderson; Wai‐Ying Wendy Yau; Zahra Shirzadi; Brian A. Gordon; Jason Hassenstab; John C. Morris; Richard J. Perrin; Ricardo F. Allegri; Nicolas R. Barthélemy; Nick Fox; Gregory S. Day; Mathias Jucker; Allan I. Levey; Johannes Levin; Hiroshi Mori; Stephen Salloway; Peter Schofield; Eric McDade; Reisa A. Sperling; Randall J. Bateman; Dennis J. Selkoe; Jasmeer P. Chhatwal; and the Dominantly Inherited Alzheimer's Network
The relationship of soluble tau species with Alzheimer's disease amyloid plaque removal and tau pathology

可溶性tau物种与阿尔茨海默病淀粉样斑块清除及tau病理的关系

Alzheimer's & Dementia
IF11.1
2025-09-230
OAAI
Eric M. McDade; Nicolas R. Barthélemy; Guoqiao Wang; Yan Li; Yuchen Cao; Brian Gordon; Tammie L. S. Benzinger; David Clifford; Alison M. Goate; Alan E. Renton; Jason Hassenstab; Jorge J. Llibre-Guerra; Richard J. Perrin; Chengjie Xiong; Carlos Cruchaga; Catherine J. Mummery; Sarah B. Berman; James Lah; Erik D. Roberson; Christopher Van Dyck; Serge Gauthier; Colin L. Masters; Mario Masellis; Tobias Bittner; Roy Yaari; Jasmeer Chhatwal; Patricio Chrem; William Brooks; Kazushi Suzuki; Johannes J. Levin; Mathias Jucker; John Ringman; David Wallon; Takeshi Ikeuchi; Jae-Hong Lee; Jee Hoon Roh; Peter Schofield; Nick C. Fox; Natalie S. Ryan; Jonathan Vöglein; Celeste Karch; Laura Ibáñez; Gregory S. Day; Raquel Sánchez-Valle; Alisha Daniels; John C. Morris; Charlene Supnet-Bell; Allan I. Levey; Randall J. Bateman; The DIAN-TU Study Team and DIAN Obs Team
Association of plasma Alzheimer's disease biomarkers with cognitive decline in cognitively unimpaired individuals

血浆阿尔茨海默病生物标志物与认知功能完好个体认知下降的关联

Alzheimer's & Dementia
IF11.1
2025-08-290
OAAI
Petrice M. Cogswell; Heather J. Wiste; Terry M. Therneau; Michael E. Griswold; Niklas Mattsson-Carlgren; Sebastian Palmqvist; Alexa Pichet Binette; Erik Stomrud; Randall J. Bateman; Nicolas Barthelemy; Joel B. Braunstein; Tim West; Philip B. Verghese; Mary M. Machulda; Jonathan Graff-Radford; Alicia Algeciras-Schimnich; Val J. Lowe; Christopher G. Schwarz; Matthew L. Senjem; Jeffrey L. Gunter; David S. Knopman; Prashanthi Vemuri; Ronald C. Petersen; Oskar Hansson; Clifford R. Jack Jr.
Stable isotope labelling kinetics of neurofilament light

神经丝轻链的稳定同位素标记动力学

BRAIN COMMUNICATIONS
IF4.5
2025-01-010
PRE
Leckey, Claire A.; Giovannucci, Tatiana A.; Coulton, John B.; He, Yingxin; Sato, Chihiro; Ghoshal, Nupur; Vignarajah, Tharini; Jaunmuktane, Zane; Barthelemy, Nicolas R.; Zetterberg, Henrik; Elbert, Donald L.; Mills, Kevin; Wray, Selina; Bateman, Randall J.; Paterson, Ross W.
Benchmarking of a multi-biomarker low-volume panel for Alzheimer's disease and related dementia research

阿尔茨海默病和相关痴呆研究的多生物标志物低容量小组的基准测试

ALZHEIMERS & DEMENTIA
IF11.1
2024-11-220
OAAI
Ibanez, Laura; Liu, Menghan; Beric, Aleksandra; Timsina, Jigyasha; Kohlfeld, Pat; Bergmann, Kristy; Lowery, Joey; Sykora, Nick; Sanchez-Montejo, Brenda; Brock, Will; Budde, John P.; Bateman, Randall J.; Barthelemy, Nicolas; Schindler, Suzanne E.; Holtzman, David M.; Benzinger, Tammie L. S.; Xiong, Chengjie; Tarawneh, Rawan; Moulder, Krista; Morris, John C.; Sung, Yun Ju; Cruchaga, Carlos
A comprehensive head-to-head comparison of key plasma phosphorylated tau 217 biomarker tests

关键血浆磷酸化tau 217生物标志物测试的全面头对头比较

BRAIN
IF11.7
2024-10-280
OAAI
Warmenhoven, Noelle; Salvado, Gemma; Janelidze, Shorena; Mattsson-Carlgren, Niklas; Bali, Divya; Dolado, Anna Orduna; Kolb, Hartmuth; Triana-Baltzer, Gallen; Barthelemy, Nicolas R.; Schindler, Suzanne E.; Aschenbrenner, Andrew J.; Raji, Cyrus A.; Benzinger, Tammie L. S.; Morris, John C.; Ibanez, Laura; Timsina, Jigyasha; Cruchaga, Carlos; Bateman, Randall J.; Ashton, Nicholas; Arslan, Burak; Zetterberg, Henrik; Blennow, Kaj; Binette, Alexa Pichet; Hansson, Oskar
Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS

血浆细胞外囊泡tau和TDP-43作为FTD和ALS的诊断生物标志物

NATURE MEDICINE
IF50
2024-06-1812
OAAI
Chatterjee, Madhurima; Ozdemir, Selcuk; Fritz, Christian; Mobius, Wiebke; Kleineidam, Luca; Mandelkow, Eckhard; Biernat, Jacek; Dogdu, Cem; Peters, Oliver; Cosma, Nicoleta Carmen; Wang, Xiao; Schneider, Luisa-Sophia; Priller, Josef; Spruth, Eike; Kuhn, Andrea A.; Krause, Patricia; Klockgether, Thomas; Vogt, Ina R.; Kimmich, Okka; Spottke, Annika; Hoffmann, Daniel C.; Fliessbach, Klaus; Miklitz, Carolin; McCormick, Cornelia; Weydt, Patrick; Falkenburger, Bjorn; Brandt, Moritz; Guenther, Rene; Dinter, Elisabeth; Wiltfang, Jens; Hansen, Niels; Bahr, Mathias; Zerr, Inga; Floel, Agnes; Nestor, Peter J.; Duzel, Emrah; Glanz, Wenzel; Incesoy, Enise; Burger, Katharina; Janowitz, Daniel; Perneczky, Robert; Rauchmann, Boris S.; Hopfner, Franziska; Wagemann, Olivia; Levin, Johannes; Teipel, Stefan; Kilimann, Ingo; Goerss, Doreen; Prudlo, Johannes; Gasser, Thomas; Brockmann, Kathrin; Mengel, David; Zimmermann, Milan; Synofzik, Matthis; Wilke, Carlo; Selma-Gonzalez, Judit; Turon-Sans, Janina; Santos-Santos, Miguel Angel; Alcolea, Daniel; Rubio-Guerra, Sara; Fortea, Juan; Carbayo, Alvaro; Lleo, Alberto; Rojas-Garcia, Ricardo; Illan-Gala, Ignacio; Wagner, Michael; Frommann, Ingo; Roeske, Sandra; Bertram, Lucas; Heneka, Michael T.; Brosseron, Frederic; Ramirez, Alfredo; Schmid, Matthias; Beschorner, Rudi; Halle, Annett; Herms, Jochen; Neumann, Manuela; Barthelemy, Nicolas R.; Bateman, Randall J.; Rizzu, Patrizia; Heutink, Peter; Dols-Icardo, Oriol; Hoeglinger, Guenter; Hermann, Andreas; Schneider, Anja
CSF neurofilament light chain profiling and quantitation in neurological diseases
BRAIN COMMUNICATIONS
IF4.5
2024-04-162
OAAI
Leckey, Claire A.; Coulton, John B.; Giovannucci, Tatiana A.; He, Yingxin; Aslanyan, Aram; Laban, Rhiannon; Heslegrave, Amanda; Doykov, Ivan; Ammoscato, Francesca; Chataway, Jeremy; De Angelis, Floriana; Gnanapavan, Sharmilee; Byrne, Lauren M.; Schott, Jonathan M.; Wild, Edward J.; Barthelemy, Nicolas R.; Zetterberg, Henrik; Wray, Selina; Bateman, Randall J.; Mills, Kevin; Paterson, Ross W.
Disease staging of Alzheimer's disease using a CSF-based biomarker model
NATURE AGING
IF19.4
2024-03-2111
OAAI
Salvado, Gemma; Horie, Kanta; Barthelemy, Nicolas R.; Vogel, Jacob W.; Pichet Binette, Alexa; Chen, Charles D.; Aschenbrenner, Andrew J.; Gordon, Brian A.; Benzinger, Tammie L. S.; Holtzman, David M.; Morris, John C.; Palmqvist, Sebastian; Stomrud, Erik; Janelidze, Shorena; Ossenkoppele, Rik; Schindler, Suzanne E.; Bateman, Randall J.; Hansson, Oskar
Comparison of cerebrospinal fluid, plasma and neuroimaging biomarker utility in Alzheimer's disease
BRAIN COMMUNICATIONS
IF4.5
2024-03-157
OAAI
Meeker, Karin L.; Luckett, Patrick H.; Barthelemy, Nicolas R.; Hobbs, Diana A.; Chen, Charles; Bollinger, James; Ovod, Vitaliy; Flores, Shaney; Keefe, Sarah; Henson, Rachel L.; Herries, Elizabeth M.; Mcdade, Eric; Hassenstab, Jason J.; Xiong, Chengjie; Cruchaga, Carlos; Benzinger, Tammie L. S.; Holtzman, David M.; Schindler, Suzanne E.; Bateman, Randall J.; Morris, John C.; Gordon, Brian A.; Ances, Beau M.
Timing of Biomarker Changes in Sporadic Alzheimer's Disease in Estimated Years from Symptom Onset
ANNALS OF NEUROLOGY
IF7.7
2024-02-2422
OA
Li, Yan; Yen, Daniel; Hendrix, Rachel D.; Gordon, Brian A.; Dlamini, Sibonginkhosi; Barthelemy, Nicolas R.; Aschenbrenner, Andrew J.; Henson, Rachel L.; Herries, Elizabeth M.; Volluz, Katherine; Kirmess, Kristopher; Eastwood, Stephanie; Meyer, Matthew; Heller, Maren; Jarrett, Lea; Mcdade, Eric; Holtzman, David M.; Benzinger, Tammie L. S.; Morris, John C.; Bateman, Randall J.; Xiong, Chengjie; Schindler, Suzanne E.
Chronic GCPII (glutamate-carboxypeptidase-II) inhibition reduces pT217Tau levels in the entorhinal and dorsolateral prefrontal cortices of aged macaques
ALZHEIMERS & DEMENTIA-TRANSLATIONAL RESEARCH & CLINICAL INTERVENTIONS
IF6.8
2023-10-314
OAAI
Bathla, Shveta; Datta, Dibyadeep; Liang, Feng; Barthelemy, Nicolas; Wiseman, Robyn; Slusher, Barbara S.; Asher, Jennifer; Zeiss, Caroline; Ekanayake-Alper, Dil; Holden, Daniel; Terwilliger, Gordon; Duque, Alvaro; Arellano, Jon; van Dyck, Christopher; Bateman, Randall J.; Xie, Zhongcong; Nairn, Angus C.; Arnsten, Amy F. T.
Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer's disease
NATURE MEDICINE
IF50
2023-08-0748
OAAI
Johnson, Erik C. B.; Bian, Shijia; Haque, Rafi U.; Carter, E. Kathleen; Watson, Caroline M.; Gordon, Brian A.; Ping, Lingyan; Duong, Duc M.; Epstein, Michael P.; McDade, Eric; Barthelemy, Nicolas R.; Karch, Celeste M.; Xiong, Chengjie; Cruchaga, Carlos; Perrin, Richard J.; Wingo, Aliza P.; Wingo, Thomas S.; Chhatwal, Jasmeer P.; Day, Gregory S.; Noble, James M.; Berman, Sarah B.; Martins, Ralph; Graff-Radford, Neill R.; Schofield, Peter R.; Ikeuchi, Takeshi; Mori, Hiroshi; Levin, Johannes; Farlow, Martin; Lah, James J.; Haass, Christian; Jucker, Mathias; Morris, John C.; Benzinger, Tammie L. S.; Roberts, Blaine R.; Bateman, Randall J.; Fagan, Anne M.; Seyfried, Nicholas T.; Levey, Allan, I
CSF MTBR-tau243 is a specific biomarker of tau tangle pathology in Alzheimer's disease
NATURE MEDICINE
IF50
2023-07-1366
OAAI
Horie, Kanta; Salvado, Gemma; Barthelemy, Nicolas R.; Janelidze, Shorena; Li, Yan; He, Yingxin; Saef, Benjamin; Chen, Charles D.; Jiang, Hong; Strandberg, Olof; Pichet Binette, Alexa; Palmqvist, Sebastian; Sato, Chihiro; Sachdev, Pallavi; Koyama, Akihiko; Gordon, Brian A.; Benzinger, Tammie L. S.; Holtzman, David M.; Morris, John C.; Mattsson-Carlgren, Niklas; Stomrud, Erik; Ossenkoppele, Rik; Schindler, Suzanne E.; Hansson, Oskar; Bateman, Randall J.

研究方向

暂未获取到该数据
R
Randall J. Bateman
H 指数:95论文数:809被引数:5.2万
C
Chihiro Sato
H 指数:31论文数:118被引数:6,233
T
Tammie L.S. Benzinger
H 指数:94论文数:1,095被引数:4.3万
K
Kanta Horie
H 指数:27论文数:123被引数:4,606
B
Brian A. Gordon
H 指数:62论文数:564被引数:1.6万
J
John C. Morris
H 指数:212论文数:2,376被引数:23.4万
C
Celeste M. Karch
H 指数:68论文数:362被引数:1.6万
S
Suzanne E. Schindler
H 指数:46论文数:297被引数:8,475
Y
Yingxin He
H 指数:19论文数:72被引数:2,336
E
Eric McDade
H 指数:64论文数:457被引数:2.1万