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S

Satoshi Koyama

riken center for integrative medical sciences
H指数:41
被引数:6,967

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A Bayesian framework for longitudinal EHR and genetic discovery

一种用于纵向电子健康记录与遗传学发现的贝叶斯框架

Nature
IF48.5
2026-07-150
OA
Sarah M. Urbut; Yi Ding; Tetsushi Nakao; Satoshi Koyama; Anika Misra; Xilin Jiang; Achyutha Harish; Leslie Gaffney; Whitney E. Hornsby; Jordan W. Smoller; Alexander Gusev; Pradeep Natarajan; Giovanni Parmigiani
Exome-wide association study of blood lipids in 1,158,017 individuals from diverse populations

不同人群1,158,017个体血脂的全外显子组关联研究

Nature Genetics
IF29
2026-05-250
OAAI
Satoshi Koyama; Zhi Yu; Seung Hoan Choi; Sean J. Jurgens; Margaret Sunitha Selvaraj; Derek Klarin; Jennifer E. Huffman; Shoa L. Clarke; Selena K. Zhang; Michael N. Trinh; Akshaya Ravi; Jacqueline S. Dron; Catherine Spinks; Ida Surakka; Aarushi Bhatnagar; Kim Lannery; Whitney Hornsby; Scott M. Damrauer; Kyong-Mi Chang; Julie A. Lynch; Themistocles L. Assimes; Philip S. Tsao; Daniel J. Rader; Kelly Cho; Gina M. Peloso; Patrick T. Ellinor; Yan V. Sun; Peter W. F. Wilson; Pradeep Natarajan
An integrated germline and somatic genomic model for coronary artery disease

冠心病整合了生殖细胞和体细胞基因组模型

Nature Communications
IF15.7
2026-03-260
OAAI
Xiong Yang; Min Seo Kim; Xinyu Zhu; Md Mesbah Uddin; Tetsushi Nakao; So Mi Jemma Cho; Satoshi Koyama; Tingfeng Xu; Laurens F. Reeskamp; Rufan Zhang; Zhaoqi Liu; Yunga A; Paul S. de Vries; Ramachandran S. Vasan; Eric Boerwinkle; Alanna C. Morrison; Bruce M. Psaty; Russell P. Tracy; Susan R. Heckbert; Michael H. Cho; Jeong H. Yun; Nicholette D. Palmer; Donald W. Bowden; Joanne M. Murabito; Daniel Levy; Nancy L. Heard-Costa; George T. O’Connor; Lewis C. Becker; Brian G. Kral; Lisa R. Yanek; Laura M. Raffield; Bertha Hidalgo; Jerome I. Rotter; Stephen S. Rich; Kent D. Taylor; Wendy S. Post; Charles Kooperberg; Alexander P. Reiner; Braxton D. Mitchell; Sharon L. R. Kardia; Jennifer A. Smith; Patricia A. Peyser; Lawrence F. Bielak; Dong Keon Yon; Hong-Hee Won; Donna K. Arnett; Albert V. Smith; Stacey B. Gabriel; Patrick T. Ellinor; Pradeep Natarajan; Minxian Wang; Akl C. Fahed
Genomic, phenomic and geographic associations of leukocyte telomere length in the United States

美国人群白细胞端粒长度与基因组、表型组及地理区域的关联

Nature Genetics
IF29
2026-03-010
OA
Nakao, Tetsushi; Koyama, Satoshi; Truong, Buu; Uddin, Md Mesbah; Misra, Anika; Patel, Aniruddh P.; Bhatnagar, Aarushi; Viscosi, Victoria; Vlasschaert, Caitlyn; Bick, Alexander G.; Nelson, Christopher P.; Codd, Veryan; Samani, Nilesh J.; Hornsby, Whitney; Ellinor, Patrick T.; Natarajan, Pradeep
Genomic and transcriptomic analyses of aortic stenosis enhance therapeutic target discovery and disease prediction

主动脉狭窄的基因组和转录组学分析可增强治疗靶点的发现和疾病预测

Nature Genetics
IF29
2025-12-190
OAAI
Aeron M. Small; Ta-Yu Yang; Shinsuke Itoh; Sébastien Thériault; Line Dufresne; Ryo Kurosawa; Issei Komuro; Koichi Matsuda; Ha My T. Vy; Eric H. Farber-Eger; Lauren Lee Shaffer; Kristin M. Boulier; Kristin M. Corey; Megan E. Ramaker; Fabien Laporte; Jean-Jacques Schott; Solena Le Scouarnec; Sasha A. Singh; Abhijeet R. Sonawane; Harry A. Smith; Nicholas Rafaels; Jonas Ghouse; Anna A. Raja; Sisse R. Ostrowski; Erik Sørensen; Christina Mikkelsen; Ole B. Pedersen; Christian Erikstrup; Henrik Ullum; Gardar Sveinbjornsson; Daniel F. Gudbjartsson; Erik Abner; Jiwoo Lee; Andrea Ganna; Ulrike Nowak-Göttl; Sarah Finer; Johannes Schumacher; Carlo Maj; Baravan Al-Kassou; Georg Nickenig; Teresa Trenkwalder; Martina Dreβen; Markus Krane; Markus M. Nöthen; Marta R. Moksnes; Ben M. Brumpton; Stacey Knight; Kirk U. Knowlton; Lincoln Nadauld; Radek Debiec; Muntaser D. Musameh; Peter S. Braund; Christopher P. Nelson; Tomasz Czuba; Olle Melander; Margaret Sunitha Selvaraj; Satoshi Koyama; Rohan Bhukar; Yunfeng Ruan; Johan Ljungberg; Scott M. Damrauer; Michael G. Levin; Andre Franke; Klaus Berger; Christian T. Ruff; Giorgio E. M. Melloni; Frederick K. Kamanu; Kaoru Ito; Ron Do; Ruth J. F. Loos; Heribert Schunkert; Quinn S. Wells; Svati H. Shah; Thierry Le Tourneau; David Messika-Zeitoun; Christopher Gignoux; Henning Bundgaard; Susanna C. Larsson; Karl Michaëlsson; Hilma Holm; Anna Helgadottir; Tonu Esko; David A. van Heel; Patrick Mathieu; Nilesh J. Samani; J. Gustav Smith; Stefan Söderberg; Daniel J. Rader; Nicholas A. Marston; Marc S. Sabatine; Bogdan Pasaniuc; Kelly Cho; Peter W. F. Wilson; Christopher J. O’Donnell; Kari Stefansson; Yohan Bossé; Elena Aikawa; James C. Engert; Gina M. Peloso; Pradeep Natarajan; George Thanassoulis
Multitrait analyses identify genetic variants associated with aortic valve function and aortic stenosis risk

多性状分析鉴定与主动脉瓣功能及主动脉瓣狭窄风险相关的遗传变异

Nature Genetics
IF29
2025-12-190
OAAI
Shinwan Kany; Joel T. Rämö; Cody Hou; Sean J. Jurgens; Shaan Khurshid; Victor Nauffal; Jonathan W. Cunningham; Emily S. Lau; Satoshi Koyama; Jennifer E. Ho; Jeffrey E. Olgin; Sammy Elmariah; Aarno Palotie; Mark E. Lindsay; Patrick T. Ellinor; James P. Pirruccello
Genetics and context for precision health in Greater Boston

精准健康在大波士顿地区的遗传学与背景

Nature Communications
IF15.7
2025-11-260
OAAI
Satoshi Koyama; Ying Wang; Kaavya Paruchuri; Md Mesbah Uddin; So Mi J. Cho; Sarah M. Urbut; Yang Sui; Akl C. Fahed; Himani Kamineni; Sara Haidermota; Whitney E. Hornsby; Robert C. Green; Mark J. Daly; Benjamin M. Neale; Patrick T. Ellinor; Jordan W. Smoller; Susan A. Slaugenhaupt; Matthew S. Lebo; Elizabeth W. Karlson; Alicia R. Martin; Pradeep Natarajan
Genome-wide analysis of heart failure yields insights into disease heterogeneity and enables prognostic prediction in the Japanese population

全基因组分析对心力衰竭的研究揭示了疾病异质性，并使对日本人群的预后预测成为可能。

Nature Communications
IF15.7
2025-11-030
OAAI
Nobuyuki Enzan; Kazuo Miyazawa; Satoshi Koyama; Ryo Kurosawa; Hirotaka Ieki; Hiroki Yoshida; Fumie Takechi; Masashi Fukuyama; Ryosuke Osako; Kohei Tomizuka; Xiaoxi Liu; Kouichi Ozaki; Yoshihiro Onouchi; Koichi Matsuda; Yukihide Momozawa; Hiroyuki Aburatani; Yoichiro Kamatani; Takanori Yamaguchi; Hiroshi Akazawa; Koichi Node; Patrick T. Ellinor; Michael G. Levin; Scott M. Damrauer; Benjamin F. Voight; Jacob Joseph; Yan V. Sun; Chikashi Terao; Toshiharu Ninomiya; Issei Komuro; Kaoru Ito
Population-scale Analysis Reveals Germline Loss of SERPING1 (C1-Inhibitor) is a Polyphenotypic Thrombotic Disorder

人群规模分析揭示，SERPING1（C1抑制因子）的生殖系缺失是一种多表型血栓性疾病

Blood Advances
IF7.1
2025-10-060
OAAI
Alfonso Rodriguez Espada; Amelia K. Haj; Sean J. Jurgens; Harish Eswaran; Linda Sundler Bjorkman; Justine Ryu; Sharjeel Chaudry; Satoshi Koyama; Xin Wang; Seung Hoan Choi; Simone Sanna-Cherchi; Aleena Banerji; Joel T. Rämö; Patrick T. Ellinor; Steven P. Grover; Pavan K. Bendapudi
Coagulation factor XII haploinsufficiency is protective against venous thromboembolism in a population-scale multidimensional analysis

凝血因子XII半合子不足在人口规模的多维分析中对静脉血栓栓塞具有保护作用

Nature Communications
IF15.7
2025-09-010
OAAI
Amelia K. Haj; David S. Paul; Sean J. Jurgens; Harish Eswaran; Lu-Chen Weng; Justine Ryu; Alfonso Rodriguez Espada; Sharjeel Chaudhry; Louis M. Feingold; Kristen Burke; Satoshi Koyama; Xin Wang; Joyce Francis; Seung Hoan Choi; Nigel Mackman; Wolfgang Bergmeier; Alex Burgin; Joel T. Rämö; Patrick T. Ellinor; Steven P. Grover; Pavan K. Bendapudi
Genomic Drivers of Coronary Artery Disease and Risk of Future Outcomes After Coronary Angiography

冠状动脉疾病的基因组驱动因素及冠状动脉造影后未来结局的风险

JAMA NETWORK OPEN
IF9.7
2025-01-211
OA
Supriami, Kelvin; Urbut, Sarah M.; Tello-Ayala, Jose R.; Unlu, Ozan; Friedman, Samuel F.; Abou-Karam, Roukoz; Koyama, Satoshi; Uddin, Md Mesbah; Pomerantsev, Eugene; Lu, Michael T.; Honigberg, Michael C.; Aragam, Krishna G.; Doshi-Velez, Finale; Patel, Aniruddh P.; Ellinor, Patrick T.; Fahed, Akl C.
Genome-wide association study reveals mechanisms underlying dilated cardiomyopathy and myocardial resilience (NOV, 10.1038/s41588-024-01975-5, 2024)

全基因组关联研究揭示扩张型心肌病和心肌弹性的机制 (NOV，10.1038/s41588-024-01975-5，2024)

NATURE GENETICS
IF31.8
2024-12-040
OAAI
Jurgens, Sean J.; Raemoe, Joel T.; Kramarenko, Daria R.; Wijdeveld, Leonoor F. J. M.; Haas, Jan; Chaffin, Mark D.; Garnier, Sophie; Gaziano, Liam; Weng, Lu-Chen; Lipov, Alex; Zheng, Sean L.; Henry, Albert; Huffman, Jennifer E.; Challa, Saketh; Ruehle, Frank; Verdugo, Carmen Diaz; Juarez, Christian Krijger; Kany, Shinwan; van Orsouw, Constance A.; Biddinger, Kiran; Poel, Edwin; Elliott, Amanda L.; Wang, Xin; Francis, Catherine; Ruan, Richard; Koyama, Satoshi; Beekman, Leander; Zimmerman, Dominic S.; Deleuze, Jean-Francois; Villard, Eric; Tregouet, David-Alexandre; Isnard, Richard; Boomsma, Dorret I.; de Geus, Eco J. C.; Tadros, Rafik; Pinto, Yigal M.; Wilde, Arthur A. M.; Hottenga, Jouke-Jan; Sinisalo, Juha; Niiranen, Teemu; Walsh, Roddy; Schmidt, Amand F.; Choi, Seung Hoan; Chang, Kyong-Mi; Tsao, Philip S.; Matthews, Paul M.; Ware, James S.; Lumbers, R. Thomas; van der Crabben, Saskia; Laukkanen, Jari; Palotie, Aarno; Amin, Ahmad S.; Charron, Philippe; Meder, Benjamin; Ellinor, Patrick T.; Daly, Mark; Aragam, Krishna G.; Bezzina, Connie R.
Genome-wide association study reveals mechanisms underlying dilated cardiomyopathy and myocardial resilience

全基因组关联研究揭示扩张型心肌病和心肌弹性的机制

NATURE GENETICS
IF31.8
2024-11-211
OAAI
Jurgens, Sean J.; Raemoe, Joel T.; Kramarenko, Daria R.; Wijdeveld, Leonoor F. J. M.; Haas, Jan; Chaffin, Mark D.; Garnier, Sophie; Gaziano, Liam; Weng, Lu-Chen; Lipov, Alex; Zheng, Sean L.; Henry, Albert; Huffman, Jennifer E.; Challa, Saketh; Ruehle, Frank; Verdugo, Carmen Diaz; Krijger Juarez, Christian; Kany, Shinwan; van Orsouw, Constance A.; Biddinger, Kiran; Poel, Edwin; Elliott, Amanda L.; Wang, Xin; Francis, Catherine; Ruan, Richard; Koyama, Satoshi; Beekman, Leander; Zimmerman, Dominic S.; Deleuze, Jean-Francois; Villard, Eric; Tregouet, David-Alexandre; Isnard, Richard; Boomsma, Dorret I.; de Geus, Eco J. C.; Tadros, Rafik; Pinto, Yigal M.; Wilde, Arthur A. M.; Hottenga, Jouke-Jan; Sinisalo, Juha; Niiranen, Teemu; Walsh, Roddy; Schmidt, Amand F.; Choi, Seung Hoan; Chang, Kyong-Mi; Tsao, Philip S.; Matthews, Paul M.; Ware, James S.; Lumbers, R. Thomas; van der Crabben, Saskia; Laukkanen, Jari; Palotie, Aarno; Amin, Ahmad S.; Charron, Philippe; Meder, Benjamin; Ellinor, Patrick T.; Daly, Mark; Aragam, Krishna G.; Bezzina, Connie R.
Integrative proteomic analyses across common cardiac diseases yield mechanistic insights and enhanced prediction

跨常见心脏疾病的综合蛋白质组学分析可产生机制见解和增强的预测

cardiovascular research
IF10.8
2024-11-210
OAAI
Schuermans, Art; Pournamdari, Ashley B.; Lee, Jiwoo; Bhukar, Rohan; Ganesh, Shriienidhie; Darosa, Nicholas; Small, Aeron M.; Yu, Zhi; Hornsby, Whitney; Koyama, Satoshi; Kooperberg, Charles; Reiner, Alexander P.; Januzzi, James L.; Honigberg, Michael C.; Natarajan, Pradeep

研究方向

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Pradeep Natarajan
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Michael C. Honigberg
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Yoichiro Kamatani
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H 指数:66论文数:569被引数:1.5万
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Takahiro Horie
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So Mi Jemma Cho
H 指数:24论文数:93被引数:4,268