Jennifer E. Huffman - Publications, H-index & Citations

Jennifer E. Huffman

VA Boston Healthcare System

88H指数

342论文数

3.5W被引数

收录论文 121

发表时间

Exome-wide association study of blood lipids in 1,158,017 individuals from diverse populations 不同人群1,158,017个体血脂的全外显子组关联研究

Nature Genetics

IF29

2026-05-25

OAAI

Satoshi Koyama; Zhi Yu; Seung Hoan Choi; Sean J. Jurgens; Margaret Sunitha Selvaraj; Derek Klarin; Jennifer E. Huffman; Shoa L. Clarke; Selena K. Zhang; Michael N. Trinh; Akshaya Ravi; Jacqueline S. Dron; Catherine Spinks; Ida Surakka; Aarushi Bhatnagar; Kim Lannery; Whitney Hornsby; Scott M. Damrauer; Kyong-Mi Chang; Julie A. Lynch; Themistocles L. Assimes; Philip S. Tsao; Daniel J. Rader; Kelly Cho; Gina M. Peloso; Patrick T. Ellinor; Yan V. Sun; Peter W. F. Wilson; Pradeep Natarajan

Leveraging Large-Scale Biobanks for Therapeutic Target Discovery 利用大规模生物银行进行治疗靶点发现

Human Genetics and Genomics Advances

IF3.6

2025-12-09

OAAI

Brian R. Ferolito; Hesam Dashti; Claudia Giambartolomei; Gina M. Peloso; Daniel J. Golden; Kai Gravel-Pucillo; Danielle Rasooly; Andrea RVR Horimoto; Rachael Matty; Liam Gaziano; Yi Liu; Ines A. Smit; Barbara Zdrazil; Yakov Tsepilov; Lauren Costa; Nicole Kosik; Jennifer E. Huffman; Gian Gaetano Tartaglia; Giorgio Bini; Gabriele Proietti

HISTORICAL REVIEW: MORE THAN TWO DECADES UNDERSTANDING THE GENETIC ARCHITECTURE OF HEMOSTASIS AND THROMBOSIS 历史回顾：二十多年对止血和血栓形成遗传结构的理解

Journal of Thrombosis and Haemostasis

IF5

2025-12-04

OAAI

Maria Sabater-Lleal; Florian Thibord; Paul S. de Vries; Jennifer Huffman; Alisa S. Wolberg; Charles J. Lowenstein; Alanna C. Morrison; Andrew D. Johnson; Nicholas L. Smith

Rare and common variant drivers of ischemic cardiomyopathy

European Heart Journal

IF35.6

2025-11-05

OAAI

K Supriami; A Zheng; K J Biddinger; S J Jurgens; L Wijdeveld; J T Ramo; P Natarajan; C R Bezzina; J E Huffman; P T Ellinor; A C Fahed; K G Aragam

An African ancestry-specific nonsense variant in CD36 is associated with a higher risk of dilated cardiomyopathy 一种非洲血统特异性的CD36无义变体与扩张型心肌病风险升高相关

Nature Genetics

IF29

2025-10-31

OAAI

Jennifer E. Huffman; Liam Gaziano; Zeina R. Al Sayed; Renae L. Judy; Laura M. Raffield; Kiran J. Biddinger; Brian Charest; Anant Chopra; David Gagnon; Xiuqing Guo; Vera Koledova; Michael G. Levin; Yuan-I Min; James P. Pirruccello; Nosheen Reza; Richard Ruan; Shefali Setia Verma; Bharath Ambale Venkatesh; Anurag Verma; Jie Yao; John Jeffrey Carr; Juan P. Casas; Kelly Cho; Joao A. C. Lima; Wendy S. Post; Daniel J. Rader; Marylyn D. Ritchie; Amil Shah; Kent D. Taylor; James G. Terry; Stephen S. Rich; Christopher J. O’Donnell; Lawrence S. Phillips; Kathryn L. Lunetta; Jerome I. Rotter; Peter W. F. Wilson; J. Michael Gaziano; Scott M. Damrauer; Yan V. Sun; Patrick T. Ellinor; Jacob Joseph; Krishna G. Aragam

A semi-empirical Bayes approach for calibrating weak instrumental bias in sex-specific Mendelian randomization studies 一种半经验贝叶斯方法，用于校正性别特异性孟德尔随机化研究中的弱工具偏差

american journal of human genetics

IF0

2025-09-04

OAAI

Yu-Jyun Huang; Nuzulul Kurniansyah; Daniel F. Levey; Joel Gelernter; Jennifer E. Huffman; Kelly Cho; Peter W.F. Wilson; Daniel J. Gottlieb; Kenneth M. Rice; Tamar Sofer

Polygenic scores for obstructive sleep apnoea reveal pathways contributing to cardiovascular disease 多基因评分揭示与心血管疾病相关的阻塞性睡眠呼吸暂停通路

eBioMedicine

IF10.8

2025-06-04

OAAI

Nuzulul Kurniansyah; Satu J. Strausz; Geetha Chittoor; Shreyash Gupta; Anne E. Justice; Yana Hrytsenko; Brendan T. Keenan; Brian E. Cade; Brian W. Spitzer; Heming Wang; Jennifer Huffman; Matthew R. Moll; Bernhard Haring; Su Yon Jung; Laura M. Raffield; Robert Kaplan; Jerome I. Rotter; Stephen S. Rich; Sina A. Gharib; Traci M. Bartz; Tamar Sofer

Genetic study of von Willebrand factor antigen levels ≤ 50 IU/dL identifies variants associated with increased risk of von Willebrand disease and bleeding von Willebrand因子抗原水平≤50 IU/dL的遗传学研究确定了与血管性血友病和出血风险增加相关的变异。

Journal of Thrombosis and Haemostasis

IF5

2025-05-12

PREAI

Rachel K. Friedman; Adam S. Heath; Jennifer E. Huffman; James T. Baker; Natalie R. Hasbani; Sarah A. Gagliano Taliun; Ming–Huei Chen; Tom E. Howard; Joshua P. Lewis; Nathan Pankratz; Snehal Patil; Alex P. Reiner; Florian Thibord; Lisa R. Yanek; Jie Yao; Hung–Hsin Chen; Joanne E. Curran; Nauder Faraday; Xiuqing Guo; Marsha M. Wheeler; Kathleen A. Ryan; Xiang Zhou; Kelly Cho; Laura Almasy; Paul L. Auer; Lewis C. Becker; Peter W.F. Wilson; Eric Boerwinkle; Jeffrey R. O’Connell; Stephen S. Rich; David C. Samuels; John Blangero; Myriam Fornage; Charles Kooperberg; Rasika A. Mathias; Braxton D. Mitchell; Jerome I. Rotter; Andrew D. Johnson; Nicholas L. Smith; Zeynep H. Coban–Akdemir; Jennifer E. Below; Alanna C. Morrison; Jill M. Johnsen; Paul S. de Vries

Genome-wide meta-analysis of heavy menstrual bleeding reveals 36 risk loci 大范围月经量过多全基因组荟萃分析揭示了36个风险位点

Blood

IF23.1

2025-04-25

PREAI

Florian Thibord; Jason Cunha; Jelisaveta Džigurski; Bjoernar Tuftin; Jennifer E. Huffman; Natàlia Pujol-Gualdo; Kelly Cho; Peter W. F. Wilson; Jill M. Johnsen; Laura M. Raffield; Ming-Huei Chen; Triin Laisk; Andrew D. Johnson

Characterization of the phenotypic consequences of the Duffy-null genotype Duffy-null基因型的表型后果表征

BLOOD ADVANCES

IF7.1

2025-01-18

OAAI

Hysong, Micah R.; Shuey, Megan M.; Huffman, Jennifer E.; Auer, Paul; Reiner, Alexander; Raff, Laura M.

Comparison of methods for building polygenic scores for diverse populations 不同人群多基因评分方法的比较

HUMAN GENETICS AND GENOMICS ADVANCES

IF3.6

2025-01-01

OAAI

Gunn, Sophia; Wang, Xin; Posner, Daniel C.; Cho, Kelly; Huffman, Jennifer E.; Gaziano, Michael; Wilson, Peter W.; V. Sun, Yan; Peloso, Gina; Lunetta, Kathryn L.

Genome-wide association study reveals mechanisms underlying dilated cardiomyopathy and myocardial resilience (NOV, 10.1038/s41588-024-01975-5, 2024)全基因组关联研究揭示扩张型心肌病和心肌弹性的机制 (NOV，10.1038/s41588-024-01975-5，2024)

NATURE GENETICS

IF31.8

2024-12-04

OAAI

Jurgens, Sean J.; Raemoe, Joel T.; Kramarenko, Daria R.; Wijdeveld, Leonoor F. J. M.; Haas, Jan; Chaffin, Mark D.; Garnier, Sophie; Gaziano, Liam; Weng, Lu-Chen; Lipov, Alex; Zheng, Sean L.; Henry, Albert; Huffman, Jennifer E.; Challa, Saketh; Ruehle, Frank; Verdugo, Carmen Diaz; Juarez, Christian Krijger; Kany, Shinwan; van Orsouw, Constance A.; Biddinger, Kiran; Poel, Edwin; Elliott, Amanda L.; Wang, Xin; Francis, Catherine; Ruan, Richard; Koyama, Satoshi; Beekman, Leander; Zimmerman, Dominic S.; Deleuze, Jean-Francois; Villard, Eric; Tregouet, David-Alexandre; Isnard, Richard; Boomsma, Dorret I.; de Geus, Eco J. C.; Tadros, Rafik; Pinto, Yigal M.; Wilde, Arthur A. M.; Hottenga, Jouke-Jan; Sinisalo, Juha; Niiranen, Teemu; Walsh, Roddy; Schmidt, Amand F.; Choi, Seung Hoan; Chang, Kyong-Mi; Tsao, Philip S.; Matthews, Paul M.; Ware, James S.; Lumbers, R. Thomas; van der Crabben, Saskia; Laukkanen, Jari; Palotie, Aarno; Amin, Ahmad S.; Charron, Philippe; Meder, Benjamin; Ellinor, Patrick T.; Daly, Mark; Aragam, Krishna G.; Bezzina, Connie R.

Genome-wide association study reveals mechanisms underlying dilated cardiomyopathy and myocardial resilience 全基因组关联研究揭示扩张型心肌病和心肌弹性的机制

NATURE GENETICS

IF31.8

2024-11-21

OAAI

Jurgens, Sean J.; Raemoe, Joel T.; Kramarenko, Daria R.; Wijdeveld, Leonoor F. J. M.; Haas, Jan; Chaffin, Mark D.; Garnier, Sophie; Gaziano, Liam; Weng, Lu-Chen; Lipov, Alex; Zheng, Sean L.; Henry, Albert; Huffman, Jennifer E.; Challa, Saketh; Ruehle, Frank; Verdugo, Carmen Diaz; Krijger Juarez, Christian; Kany, Shinwan; van Orsouw, Constance A.; Biddinger, Kiran; Poel, Edwin; Elliott, Amanda L.; Wang, Xin; Francis, Catherine; Ruan, Richard; Koyama, Satoshi; Beekman, Leander; Zimmerman, Dominic S.; Deleuze, Jean-Francois; Villard, Eric; Tregouet, David-Alexandre; Isnard, Richard; Boomsma, Dorret I.; de Geus, Eco J. C.; Tadros, Rafik; Pinto, Yigal M.; Wilde, Arthur A. M.; Hottenga, Jouke-Jan; Sinisalo, Juha; Niiranen, Teemu; Walsh, Roddy; Schmidt, Amand F.; Choi, Seung Hoan; Chang, Kyong-Mi; Tsao, Philip S.; Matthews, Paul M.; Ware, James S.; Lumbers, R. Thomas; van der Crabben, Saskia; Laukkanen, Jari; Palotie, Aarno; Amin, Ahmad S.; Charron, Philippe; Meder, Benjamin; Ellinor, Patrick T.; Daly, Mark; Aragam, Krishna G.; Bezzina, Connie R.

Exome-wide association study of over a million individuals identified effector genes and variants for blood lipids 全外显子组关联研究对超过一百万个体进行了分析，确定了与血脂相关的效应基因和变异。

CIRCULATION

IF38.6

2024-11-12

PREAI

Koyama, Satoshi; Yu, Zhi; Choi, Seung Hoan; Jurgens, Sean; Selvaraj, Margaret; Klarin, Derek; Huffman, Jennifer; Trinh, Michael; Ravi, Akshaya; Dron, Jacqueline; Spinks, Catherine; Surakka, Ida; Hornsby, Whitney; Damrauer, Scott; Chang, Kyong-Mi; Assimes, Themistocles; Tsao, Philip; Rader, Daniel; Kim, Kelly; Peloso, Gina; Ellinor, Patrick; Sun, Yan; Wilson, Peter; Natarajan, Pradeep

Lipid levels and risk of acute pancreatitis using bidirectional Mendelian randomization 使用双向孟德尔随机化的脂质水平和急性胰腺炎的风险

SCIENTIFIC REPORTS

IF3.9

2024-03-15

OAAI

Wang, Biqi; Dron, Jacqueline S.; Wang, Yuxuan; Choi, Seung Hoan; Huffman, Jennifer E.; Cho, Kelly; Wilson, Peter W. F.; Natarajan, Pradeep; Peloso, Gina M.

Factors that modulate platelet reactivity as measured by 5 assay platforms in 3429 individuals

RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS

IF3.4

2024-03-01

OAAI

V. Chan, Melissa; Chen, Ming-Huei; Thibord, Florian; Nkambule, Bongani B.; Lachapelle, Amber R.; Grech, Joseph; Schneider, Zoe E.; de Melendez, Catherine Wallace; Huffman, Jennifer E.; Hayman, Melissa A.; Allan, Harriet E.; Armstrong, Paul C.; Warner, Timothy D.; Johnson, Andrew D.

GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors 自杀尝试的GWAS荟萃分析: 鉴定了12个全基因组重要基因座，并暗示了特定健康因素的遗传风险

AMERICAN JOURNAL OF PSYCHIATRY

IF14.7

2023-10-01

OAAI

Docherty, Anna R.; Mullins, Niamh; Ashley-Koch, Allison E.; Qin, Xuejun; Coleman, Jonathan R. I.; Shabalin, Andrey; Kang, JooEun; Murnyak, Balasz; Wendt, Frank; Adams, Mark; Campos, Adrian I.; DiBlasi, Emily; Fullerton, Janice M.; Kranzler, Henry R.; Bakian, Amanda V.; Monson, Eric T.; Renteria, Miguel E.; Walss-Bass, Consuelo; Andreassen, Ole A.; Behera, Chittaranjan; Bulik, Cynthia M.; Edenberg, Howard J.; Kessler, Ronald C.; Mann, J. John; Nurnberger, John I., Jr.; Pistis, Giorgio; Streit, Fabian; Ursano, Robert J.; Polimanti, Renato; Dennis, Michelle; Garrett, Melanie; Hair, Lauren; Harvey, Philip; Hauser, Elizabeth R.; Hauser, Michael A.; Huffman, Jennifer; Jacobson, Daniel; Madduri, Ravi; McMahon, Benjamin; Oslin, David W.; Trafton, Jodie; Awasthi, Swapnil; Berrettini, Wade H.; Bohus, Martin; Chang, Xiao; Chen, Hsi-Chung; Chen, Wei J.; Christensen, Erik D.; Crow, Scott; Duriez, Philibert; Edwards, Alexis C.; Fernandez-Aranda, Fernando; Galfalvy, Hanga; Gandal, Michael; Gorwood, Philip; Guo, Yiran; Hafferty, Jonathan D.; Hakonarson, Hakon; Halmi, Katherine A.; Hishimoto, Akitoyo; Jain, Sonia; Jamain, Stephane; Jimenez-Murcia, Susana; Johnson, Craig; Kaplan, Allan S.; Keel, Pamela K.; Kennedy, James L.; Kim, Minsoo; Klump, Kelly L.; Levey, Daniel F.; Li, Dong; Liao, Shih-Cheng; Lieb, Klaus; Lilenfeld, Lisa; Marshall, Christian R.; Mitchell, James E.; Okazaki, Satoshi; Otsuka, Ikuo; Pinto, Dalila; Powers, Abigail; Ramoz, Nicolas; Ripke, Stephan; Roepke, Stefan; Rozanov, Vsevolod; Scherer, Stephen W.; Schmahl, Christian; Sokolowski, Marcus; Starnawska, Anna; Strober, Michael; Su, Mei-Hsin; Thornton, Laura M.; Treasure, Janet; Ware, Erin B.; Watson, Hunna J.; Witt, Stephanie H.; Woodside, D. Blake; Yilmaz, Zeynep; Zillich, Lea; Adolfsson, Rolf; Agartz, Ingrid; Alda, Martin; Alfredsson, Lars; Appadurai, Vivek; Artigas, Maria Soler; Van der Auwera, Sandra; Azevedo, M. Helena; Bass, Nicholas; Bau, Claiton H. D.; Baune, Bernhard T.; Bellivier, Frank; Berger, Klaus; Biernacka, Joanna M.; Bigdeli, Tim B.; Binder, Elisabeth B.; Boehnke, Michael; Boks, Marco P.; Braff, David L.; Bryant, Richard; Budde, Monika; Byrne, Enda M.; Cahn, Wiepke; Castelao, Enrique; Cervilla, Jorge A.; Chaumette, Boris; Corvin, Aiden; Craddock, Nicholas; Djurovic, Srdjan; Foo, Jerome C.; Forstner, Andreas J.; Frye, Mark; Gatt, Justine M.; Giegling, Ina; Grabe, Hans J.; Green, Melissa J.; Grevet, Eugenio H.; Grigoroiu-Serbanescu, Maria; Gutierrez, Blanca; Guzman-Parra, Jose; Hamshere, Marian L.; Hartmann, Annette M.; Hauser, Joanna; Heilmann-Heimbach, Stefanie; Hoffmann, Per; Ising, Marcus; Jones, Ian; Jones, Lisa A.; Jonsson, Lina; Kahn, Rene S.; Kelsoe, John R.; Kendler, Kenneth S.; Kloiber, Stefan; Koenen, Karestan C.; Kogevinas, Manolis; Krebs, Marie-Odile; Landen, Mikael; Leboyer, Marion; Lee, Phil H.; Levinson, Douglas F.; Liao, Calwing; Lissowska, Jolanta; Mayoral, Fermin; McElroy, Susan L.; McGrath, Patrick; McGuffin, Peter; McQuillin, Andrew; Mehta, Divya; Melle, Ingrid; Mitchell, Philip B.; Molina, Esther; Morken, Gunnar; Nievergelt, Caroline; Nothen, Markus M.; O'Donovan, Michael C.; Ophoff, Roel A.; Owen, Michael J.; Pato, Carlos; Pato, Michele T.; Penninx, Brenda W. J. H.; Potash, James B.; Power, Robert A.; Preisig, Martin; Quested, Digby; Ramos-Quiroga, Josep Antoni; Reif, Andreas; Ribases, Marta; Richarte, Vanesa; Rietschel, Marcella; Rivera, Margarita; Roberts, Andrea; Roberts, Gloria; Rouleau, Guy A.; Rovaris, Diego L.; Sanders, Alan R.; Schofield, Peter R.; Schulze, Thomas G.; Scott, Laura J.; Serretti, Alessandro; Shi, Jianxin; Sirignano, Lea; Sklar, Pamela; Smeland, Olav B.; Smoller, Jordan W.; Sonuga-Barke, Edmund J. S.; Trzaskowski, Maciej; Tsuang, Ming T.; Turecki, Gustavo; Vilar-Ribo, Laura; Vincent, John B.; Volzke, Henry; Walters, James T. R.; Weickert, Cynthia Shannon; Weickert, Thomas W.; Weissman, Myrna M.; Williams, Leanne M.; Wray, Naomi R.; Zai, Clement C.; Agerbo, Esben; Borglum, Anders D.; Breen, Gerome; Demontis, Ditte; Erlangsen, Annette; Gelernter, Joel; Glatt, Stephen J.; Hougaard, David M.; Hwu, Hai-Gwo; Kuo, Po-Hsiu; Lewis, Cathryn M.; Li, Qingqin S.; Liu, Chih-Min; Martin, Nicholas G.; McIntosh, Andrew M.; Medland, Sarah E.; Mors, Ole; Nordentoft, Merete; Olsen, Catherine M.; Porteous, David; Smith, Daniel J.; Stahl, Eli A.; Stein, Murray B.; Wasserman, Danuta; Werge, Thomas; Whiteman, David C.; Willour, Virginia; Coon, Hilary; Beckham, Jean C.; Kimbrel, Nathan A.; Ruderfer, Douglas M.

Multi-ancestry meta-analysis identifies 5 novel loci for ischemic stroke and reveals heterogeneity of effects between sexes and ancestries

CELL GENOMICS

IF9

2023-08-01

OAAI

Surakka, Ida; Wu, Kuan-Han; Hornsby, Whitney; Wolford, Brooke N.; Shen, Fred; Zhou, Wei; Huffman, Jennifer E.; Pandit, Anita; Hu, Yao; Brumpton, Ben; Skogholt, Anne Heidi; Walters, Robin G.; Hveem, Kristian; Kooperberg, Charles; Zollner, Sebastian; Wilson, Peter W. F.; Sutton, Nadia R.; Daly, Mark J.; Neale, Benjamin M.

Genome-wide association analysis and Mendelian randomization proteomics identify drug targets for heart failure 全基因组关联分析和孟德尔随机化蛋白质组学确定心力衰竭的药物靶点

NATURE COMMUNICATIONS

IF15.7

2023-07-10

OAAI

Rasooly, Danielle; Peloso, Gina M.; Pereira, Alexandre C.; Dashti, Hesam; Giambartolomei, Claudia; Wheeler, Eleanor; Aung, Nay; Ferolito, Brian R.; Pietzner, Maik; Farber-Eger, Eric H.; Wells, Quinn Stanton; Kosik, Nicole M.; Gaziano, Liam; Posner, Daniel C.; Bento, A. Patricia; Hui, Qin; Liu, Chang; Aragam, Krishna; Wang, Zeyuan; Charest, Brian; Huffman, Jennifer E.; Wilson, Peter W. F.; Phillips, Lawrence S.; Whittaker, John; Munroe, Patricia B.; Petersen, Steffen E.; Cho, Kelly; Leach, Andrew R.; Magarinos, Maria Paula; Gaziano, John Michael; Langenberg, Claudia; Sun, Yan V.; Joseph, Jacob; Casas, Juan P.

Evaluating the use of blood pressure polygenic risk scores across race/ethnic background groups 跨种族/民族背景群体评估血压多基因风险评分的使用

NATURE COMMUNICATIONS

IF15.7

2023-06-02

OAAI

Kurniansyah, Nuzulul; Goodman, Matthew O.; Khan, Alyna T.; Wang, Jiongming; Feofanova, Elena; Bis, Joshua C.; Wiggins, Kerri L.; Huffman, Jennifer E.; Kelly, Tanika; Elfassy, Tali; Guo, Xiuqing; Palmas, Walter; Lin, Henry J.; Hwang, Shih-Jen; Gao, Yan; Young, Kendra; Kinney, Gregory L.; Smith, Jennifer A.; Yu, Bing; Liu, Simin; Wassertheil-Smoller, Sylvia; Manson, JoAnn E.; Zhu, Xiaofeng; Chen, Yii-Der Ida; Lee, I-Te; Gu, C. Charles; Lloyd-Jones, Donald M.; Zoellner, Sebastian; Fornage, Myriam; Kooperberg, Charles; Correa, Adolfo; Psaty, Bruce M.; Arnett, Donna K.; Isasi, Carmen R.; Rich, Stephen S.; Kaplan, Robert C.; Redline, Susan; Mitchell, Braxton D.; Franceschini, Nora; Levy, Daniel; Rotter, Jerome I.; Morrison, Alanna C.; Sofer, Tamar

研究方向