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D

Damir Varešlija

Royal College of Surgeons in Ireland
H指数:20
被引数:1,387

个人简介

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教育背景

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工作经历

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荣誉奖项

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Design, Synthesis, and Biological Evaluation of Novel Triazine-Based Dual Histone Deacetylase/phosphatidylinositol 3-kinase Inhibitors for Breast Cancer Therapy

基于三嗪的新型组蛋白去乙酰化酶/磷脂酰肌醇3-激酶双抑制剂的设计、合成及生物活性评价：用于乳腺癌治疗

ChemMedChem
IF3.4
2026-04-250
OAAI
Lara Luzietti; Gustavo Salgado Pires; Ana Ryan; Crisamie Regidor; Matthew Hiller; Danilo Sarti; Tríona Ní Chonghaile; Pedro de Sena Murteira Pinheiro; Damir Varešlija; Daniel Alencar Rodrigues
Targeting CDK12 disrupts estrogen-receptor chromatin recruitment and ER-MED1 transcription in advanced ER+ breast cancer

靶向CDK12破坏雌激素受体染色质募集和ER-MED1转录在晚期ER+乳腺癌中的作用

JNCI: Journal of the National Cancer Institute
IF0
2025-10-150
OAAI
Daniela Ottaviani, PhD; Mihaela Ola, PhD; Alessandra Allotta, MSc; Yasmine Maati Chaibi, MSc; Seán Hickey, BSc; Petra Jagust, PhD; Nicola Cosgrove, PhD; Sinéad Cocchiglia, MSc; Fiona Bane, MSc; Ramón Fallon, MSc; Gordon Daly, MCh; Aisling Hegarty, PhD; Lance Hudson, BSc; Katherine Sheehan, MD; Shannon Kalsi, MSc; Stephen Shovlin, PhD; Aoibhín Powell, BSc; Ash Bahl, PhD; Ed Ainscow, PhD; Steffi Oesterreich, PhD; Adrian V Lee, PhD; Fergus J Couch, PhD; Arnold D K Hill, MD; Damir Varešlija, PhD; Leonie Young, PhD; null
PARP Inhibitors in the Neoadjuvant Setting; A Comprehensive Overview of the Rationale for their Use, Past and Ongoing Clinical Trials

PARP抑制剂在辅助治疗前设置中的应用；关于其使用合理性的全面概述及过去和正在进行的临床试验

CURRENT ONCOLOGY REPORTS
IF5
2025-04-070
OA
Habaka, Minatoullah; Daly, Gordon R.; Shinyanbola, Deborah; Alabdulrahman, Mohammad; Mcgrath, Jason; Dowling, Gavin P.; Hehir, Cian; Huang, Helen Ye Rim; Hill, Arnold D. K.; Vareslija, Damir; Young, Leonie S.
RET overexpression leads to increased brain metastatic competency in luminal breast cancer
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
IF7.2
2024-06-101
OAAI
Jagust, Petra; Powell, Aoibhin M.; Ola, Mihaela; Watson, Louise; de Pablos-Aragoneses, Ana; Garcia-Gomez, Pedro; Fallon, Ramon; Bane, Fiona; Heiland, Mona; Morris, Gareth; Cavanagh, Brenton; McGrath, Jason; Ottaviani, Daniela; Hegarty, Aisling; Cocchiglia, Sinead; Sweeney, Kieron J.; MacNally, Stephen; Brett, Francesca M.; Cryan, Jane; Beausang, Alan; Morris, Patrick; Valiente, Manuel; Hill, Arnold D. K.; Vareslija, Damir; Young, Leonie S.
Luminal breast cancer identity is determined by loss of glucocorticoid receptor activity

管腔型乳腺癌的身份取决于糖皮质激素受体活性的丧失

EMBO MOLECULAR MEDICINE
IF8.3
2023-10-305
OAAI
Prekovic, Stefan; Chalkiadakis, Theofilos; Roest, Merel; Roden, Daniel; Lutz, Catrin; Schuurman, Karianne; Opdam, Mark; Hoekman, Liesbeth; Abbott, Nina; Tesselaar, Tanja; Wajahat, Maliha; Dwyer, Amy R.; Mayayo-Peralta, Isabel; Gomez, Gabriela; Altelaar, Maarten; Beijersbergen, Roderick; Gyorffy, Balazs; Young, Leonie; Linn, Sabine; Jonkers, Jos; Tilley, Wayne; Hickey, Theresa; Vareslija, Damir; Swarbrick, Alexander; Zwart, Wilbert
Stratification of radiosensitive brain metastases based on an actionable S100A9/RAGE resistance mechanism
NATURE MEDICINE
IF50
2022-04-1149
OAAI
Monteiro, Catia; Miarka, Lauritz; Perea-Garcia, Maria; Priego, Neibla; Garcia-Gomez, Pedro; Alvaro-Espinosa, Laura; de Pablos-Aragoneses, Ana; Yebra, Natalia; Retana, Diana; Baena, Patricia; Fustero-Torre, Coral; Grana-Castro, Osvaldo; Troule, Kevin; Caleiras, Eduardo; Tezanos, Patricia; Muela, Pablo; Cintado, Elisa; Luis Trejo, Jose; Manuel Sepulveda, Juan; Gonzalez-Leon, Pedro; Jimenez-Roldan, Luis; Miguel Moreno, Luis; Esteban, Olga; Perez-Nunez, Angel; Hernandez-Lain, Aurelio; Mazarico Gallego, Jose; Ferrer, Irene; Suarez, Rocio; Garrido-Martin, Eva M.; Paz-Ares, Luis; Dalmasso, Celine; Moyal, Elizabeth Cohen-Jonathan; Siegfried, Aurore; Hegarty, Aisling; Keelan, Stephen; Vareslija, Damir; Young, Leonie S.; Mohme, Malte; Goy, Yvonne; Wikman, Harriet; Fernandez-Alen, Jose; Blasco, Guillermo; Alcazar, Lucia; Cabanuz, Clara; Grivennikov, Sergei, I; Ianus, Andrada; Shemesh, Noam; Faria, Claudia C.; Lee, Rebecca; Lorigan, Paul; Le Rhun, Emilie; Weller, Michael; Soffietti, Riccardo; Bertero, Luca; Ricardi, Umberto; Bosch-Barrera, Joaquim; Sais, Elia; Teixidor, Eduard; Hernandez-Martinez, Alejandro; Calvo, Alfonso; Aristu, Javier; Martin, Santiago M.; Gonzalez, Alvaro; Adler, Omer; Erez, Neta; Valiente, Manuel
A clinically compatible drug-screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis

基于器官型培养的临床兼容药物筛选平台可确定预防和治疗脑转移的漏洞

EMBO MOLECULAR MEDICINE
IF8.3
2022-02-1716
OAAI
Zhu, Lucia; Retana, Diana; Garcia-Gomez, Pedro; Alvaro-Espinosa, Laura; Priego, Neibla; Masmudi-Martin, Mariam; Yebra, Natalia; Miarka, Lauritz; Hernandez-Encinas, Elena; Blanco-Aparicio, Carmen; Martinez, Sonia; Sobrino, Cecilia; Ajenjo, Nuria; Artiga, Maria-Jesus; Ortega-Paino, Eva; Torres-Ruiz, Raul; Rodriguez-Perales, Sandra; Soffietti, Riccardo; Bertero, Luca; Cassoni, Paola; Weiss, Tobias; Munoz, Javier; Manuel Sepulveda, Juan; Gonzalez-Leon, Pedro; Jimenez-Roldan, Luis; Miguel Moreno, Luis; Esteban, Olga; Perez-Nunez, Angel; Hernandez-Lain, Aurelio; Toldos, Oscar; Ruano, Yolanda; Alcazar, Lucia; Blasco, Guillermo; Fernandez-Alen, Jose; Caleiras, Eduardo; Lafarga, Miguel; Megias, Diego; Grana-Castro, Osvaldo; Nor, Carolina; Taylor, Michael D.; Young, Leonie S.; Vareslija, Damir; Cosgrove, Nicola; Couch, Fergus J.; Cusso, Lorena; Desco, Manuel; Mouron, Silvana; Quintela-Fandino, Miguel; Weller, Michael; Pastor, Joaquin; Valiente, Manuel
Mapping molecular subtype specific alterations in breast cancer brain metastases identifies clinically relevant vulnerabilities
NATURE COMMUNICATIONS
IF15.7
2022-01-2650
OAAI
Cosgrove, Nicola; Vareslija, Damir; Keelan, Stephen; Elangovan, Ashuvinee; Atkinson, Jennifer M.; Cocchiglia, Sinead; Bane, Fiona T.; Singh, Vikrant; Furney, Simon; Hu, Chunling; Carter, Jodi M.; Hart, Steven N.; Yadav, Siddhartha; Goetz, Matthew P.; Hill, Arnold D. K.; Oesterreich, Steffi; Lee, Adrian, V; Couch, Fergus J.; Young, Leonie S.
Comparative analysis of the AIB1 interactome in breast cancer reveals MTA2 as a repressive partner which silences E-Cadherin to promote EMT and associates with a pro-metastatic phenotype
ONCOGENE
IF7.3
2021-01-0812
OAAI
Vareslija, Damir; Ward, Elspeth; Purcell, Siobhan P.; Cosgrove, Nicola S.; Cocchiglia, Sinead; O'Halloran, Philip J.; Charmsaz, Sara; Bane, Fiona T.; Brett, Francesca M.; Farrell, Michael; Cryan, Jane; Beausang, Alan; Hudson, Lance; Turnbul, Arran K.; Dixon, J. Michael; Hill, Arnold D. K.; Priedigkeit, Nolan; Oesterreich, Steffi; Lee, Adrian V.; Sims, Andrew H.; Redmond, Aisling M.; Carroll, Jason S.; Young, Leonie S.

研究方向

暂未获取到该数据
L
Leonie S. Young
H 指数:37论文数:417被引数:4,795
A
Arnold D. Hill
H 指数:37论文数:416被引数:6,051
S
Sinéad Cocchiglia
H 指数:15论文数:73被引数:862
C
Cosgrove, Nicola
H 指数:0论文数:1被引数:16
F
Fiona T. Bane
H 指数:12论文数:110被引数:516
A
Ailís Fagan
H 指数:18论文数:95被引数:1,426
S
Siobhan Purcell
H 指数:7论文数:32被引数:280
L
Lance Hudson
H 指数:16论文数:84被引数:878
S
Steffi Oesterreich
H 指数:63论文数:897被引数:1.6万
E
Elspeth Ward
H 指数:7论文数:30被引数:324