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S

Sylvia Fong

queen's university
H指数:22
被引数:1,652

个人简介

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工作经历

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荣誉奖项

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Evaluation of early prophylactic corticosteroid administration on early safety and efficacy outcomes of AAV gene therapy in the hemophilia dog model

AAV基因疗法中早期预防性糖皮质激素给药对血友病犬模型早期安全性和有效性结局的评估

Journal of Thrombosis and Haemostasis
IF5
2026-08-220
PRE
Paul Batty; Laura L. Swystun; Britta Handyside; Alexandre Menard; Lori Harpell; David Hurlbut; A.M. Ismail; Aomei Mo; Abbey Pender; Sebastian Brennan; Andrew Winterborn; Bridget Yates; Sylvia Fong; David Lillicrap
BMN 349, a small molecule inhibitor of Z alpha-1 antitrypsin polymerization, increases secretion and reduces intrahepatic inclusions in a mouse model of disease

BMN 349，一种Z α-1抗胰蛋白酶聚合的小分子抑制剂，可增加分泌并减少疾病小鼠模型中的肝内包涵体

Hepatology
IF15.8
2026-05-010
PRE
Handyside, Britta; Wenzel, Heather; Mackenzie, Donald; Chang, Catherine; Greenslade, Annie; Van Vleet, Jeremy; Heglar, Brian; Chen, Joseph C.; Zhang, Lening; Larimore, Kevin; Zhou, Huiyu; Trantcheva, Iva; Sims, Lawrence; Evans, Kristin; Fong, Sylvia; Kumar, Gyanendra; Annu, Kavya; Ronzoni, Riccardo; Irving, James A.; Wang, Bing; Bunting, Stuart; Lomas, David A.
Intracerebroventricular administration of a modified hexosaminidase ameliorates late-stage neurodegeneration in a GM2 mouse model

脑室内给予一种改良的己糖胺酶可改善GM2小鼠模型的晚期神经退行性病变

PLOS ONE
IF2.6
2025-01-030
OA
Lopez, Manuel E.; Wendt, Daniel; Lawrence, Roger; Gong, Kerui; Ong, Hoonsan; Yip, Bryan; Chen, Joseph; Mangini, Linley; Handyside, Britta; Giaramita, Alexander; Lamichhane, Aashish; Lo, Melanie; Agrawal, Vishal; Van Vleet, Jeremy; Abolhesn, Amanda; Felix, Jessica B.; Villalpando, Isaac; Bhat, Vikas; De Angelis, Rolando; Ru, Yuanbin; Khan, Ayesha; Fong, Sylvia; Christianson, Terri; Bullens, Sherry; Crawford, Brett E.; Bunting, Stuart; Aoyagi-Scharber, Mika
Vector genome loss and epigenetic modifications mediate decline in transgene expression of AAV5 vectors produced in mammalian and insect cells
MOLECULAR THERAPY
IF12
2022-12-0118
OAAI
Handyside, Britta; Ismail, Ashrafali Mohamed; Zhang, Lening; Yates, Bridget; Xie, Lin; Sihn, Choong-Ryoul; Murphy, Ryan; Bouwman, Taren; Kim, Chan Kyu; De Angelis, Rolando; Karim, Omair A.; McIntosh, Nicole L.; Doss, Michael Xavier; Shroff, Shilpa; Pungor, Erno; Bhat, Vikas S.; Bullens, Sherry; Bunting, Stuart; Fong, Sylvia
Intracerebroventricular dosing of N-sulfoglucosamine sulfohydrolase in mucopolysaccharidosis IIIA mice reduces markers of brain lysosomal dysfunction
JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2022-12-011
OAAI
Magat, Jenna; Jones, Samantha; Baridon, Brian; Agrawal, Vishal; Wong, Hio; Giaramita, Alexander; Mangini, Linley; Handyside, Britta; Vitelli, Catherine; Parker, Monica; Yeung, Natasha; Zhou, Yu; Pungor, Erno; Slabodkin, Ilya; Gorostiza, Olivia; Aguilera, Allora; Lo, Melanie J.; Alcozie, Saida; Christianson, Terri M.; Tiger, Pascale M. N.; Vincelette, Jon; Fong, Sylvia; Gil, Geuncheol; Hague, Chuck; Lawrence, Roger; Wendt, Daniel J.; Lebowitz, Jonathan H.; Bunting, Stuart; Bullens, Sherry; Crawford, Brett E.; Roy, Sushmita M.; Woloszynek, Josh C.
Interindividual variability in transgene mRNA and protein production following adeno-associated virus gene therapy for hemophilia A

血友病A的腺相关病毒基因治疗后转基因mRNA和蛋白质产生的个体间差异

NATURE MEDICINE
IF50
2022-04-1172
OAAI
Fong, Sylvia; Yates, Bridget; Sihn, Choong-Ryoul; Mattis, Aras N.; Mitchell, Nina; Liu, Su; Russell, Chris B.; Kim, Benjamin; Lawal, Adebayo; Rangarajan, Savita; Lester, Will; Bunting, Stuart; Pierce, Glenn F.; Pasi, K. John; Wong, Wing Yen
Intracerebroventricular enzyme replacement therapy with β-galactosidase reverses brain pathologies due to GM1 gangliosidosis in mice
JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2020-09-0132
OAAI
Chen, Joseph C.; Luu, Amanda R.; Wise, Nathan; De Angelis, Rolando; Agrawal, Vishal; Mangini, Linley; Vincelette, Jon; Handyside, Britta; Sterling, Harry; Lo, Melanie J.; Wong, Hio; Galicia, Nicole; Pacheco, Glenn; Van Vleet, Jeremy; Giaramita, Alexander; Fong, Sylvia; Roy, Sushmita M.; Hague, Chuck; Lawrence, Roger; Bullens, Sherry; Christianson, Terri M.; d'Azzo, Alessandra; Crawford, Brett E.; Bunting, Stuart; LeBowitz, Jonathan H.; Yogalingam, Gouri
Adenovirus-associated antibodies in UK cohort of hemophilia patients: A seroprevalence study of the presence of adenovirus-associated virus vector-serotypes AAV5 and AAV8 neutralizing activity and antibodies in patients with hemophilia A
RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS
IF3.4
2019-04-0141
OAAI
Stanford, Sophia; Pink, Ruth; Creagh, Desmond; Clark, Amanda; Lowe, Gillian; Curry, Nicola; Pasi, John; Perry, David; Fong, Sylvia; Hayes, Gregory; Chandrakumaran, Kandiah; Rangarajan, Savita
Vascular endothelial platelet endothelial cell adhesion molecule 1 (PECAM-1) regulates advanced metastatic progression
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2010-10-0677
OAAI
DeLisser, Horace; Liu, Yong; Desprez, Pierre-Yves; Thor, Ann; Briasouli, Paraskevei; Handumrongkul, Chakrapong; Wilfong, Jonathon; Yount, Garret; Nosrati, Mehdi; Fong, Sylvia; Shtivelman, Emma; Fehrenbach, Melane; Cao, Gaoyuan; Moore, Dan H.; Nyack, Shruti; Liggitt, Denny; Kashani-Sabet, Mohammed; Debs, Robert

研究方向

暂未获取到该数据
R
Robert J. Debs
H 指数:38论文数:111被引数:5,938
B
Britta Handyside
H 指数:8论文数:20被引数:289
S
Stuart Bunting
H 指数:46论文数:144被引数:1.3万
M
Mohammed Kashani–Sabet
H 指数:57论文数:368被引数:1.1万
P
Pierre‐Yves Desprez
H 指数:41论文数:206被引数:1.4万
S
Sherry Bullens
H 指数:13论文数:44被引数:1,054
M
Mehdi Nosrati
H 指数:30论文数:193被引数:3,052
B
Bridget Yates
H 指数:9论文数:34被引数:523
E
Emma Shtivelman
H 指数:35论文数:65被引数:5,089
P
Paul Batty
H 指数:18论文数:67被引数:1,858