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D

Daniel J. Sheward

karolinska institutet
H指数:29
被引数:5,121

个人简介

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工作经历

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荣誉奖项

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Generation of antigen-specific paired-chain antibodies using large language models

利用大型语言模型生成抗原特异性成对链抗体

Cell
IF42.5
2025-11-040
OAAI
Perry T. Wasdin; Nicole V. Johnson; Alexis K. Janke; Sofia Held; Toma M. Marinov; Gwen Jordaan; Rebecca A. Gillespie; Léna Vandenabeele; Fani Pantouli; Olivia C. Powers; Matthew J. Vukovich; Clinton M. Holt; Jeongryeol Kim; Grant Hansman; Jennifer Logue; Helen Y. Chu; Sarah F. Andrews; Masaru Kanekiyo; Giuseppe A. Sautto; Ted M. Ross; Daniel J. Sheward; Jason S. McLellan; Alexandra A. Abu-Shmais; Ivelin S. Georgiev
Isolation and characterization of IgG3 glycan-targeting antibodies with exceptional cross-reactivity for diverse viral families
PLOS PATHOGENS
IF4.9
2024-09-181
OAAI
Vukovich, Matthew J.; Shiakolas, Andrea R.; Lindenberger, Jared; Richardson, Robert A.; Bass, Lindsay E.; Barr, Maggie; Liu, Yanshun; Go, Eden P.; Park, Chan Soo; May, Aaron J.; Sammour, Salam; Kambarami, Chipo; Huang, Xiao; Janowska, Katarzyna; Edwards, Robert J.; Mansouri, Katayoun; Spence, Taylor N.; Abu-Shmais, Alexandra A.; Manamela, Nelia P.; Richardson, Simone I.; Leonard, Sabina E. W.; Gripenstraw, Kathryn R.; Setliff, Ian; Saunders, Kevin O.; Bonami, Rachel H.; Ross, Ted M.; Desaire, Heather; Moore, Penny L.; Parks, Robert; Haynes, Barton F.; Sheward, Daniel J.; Acharya, Priyamvada; Sautto, Giuseppe A.; Georgiev, Ivelin S.
Multi-compartmental diversification of neutralizing antibody lineages dissected in SARS-CoV-2 spike-immunized macaques
NATURE COMMUNICATIONS
IF15.7
2024-07-270
OAAI
Mandolesi, Marco; Das, Hrishikesh; de Vries, Liset; Yang, Yiqiu; Kim, Changil; Dhinakaran, Manojj; Castro Dopico, Xaquin; Fischbach, Julian; Kim, Sungyong; Guryleva, Mariia V.; Adori, Monika; Chernyshev, Mark; Stalmarck, Aron; Hanke, Leo; Mcinerney, Gerald M.; Sheward, Daniel J.; Corcoran, Martin; Haellberg, B. Martin; Murrell, Ben; Karlsson Hedestam, Gunilla B.
Structural basis of broad SARS-CoV-2 cross-neutralization by affinity-matured public antibodies
CELL REPORTS MEDICINE
IF10.6
2024-06-014
OAAI
Sheward, Daniel J.; Pushparaj, Pradeepa; Das, Hrishikesh; Greaney, Allison J.; Kim, Changil; Kim, Sungyong; Hanke, Leo; Hyllner, Erik; Dyrdak, Robert; Lee, Jimin; Dopico, Xaquin Castro; Dosenovic, Pia; Peacock, Thomas P.; McInerney, Gerald M.; Albert, Jan; Corcoran, Martin; Bloom, Jesse D.; Murrell, Ben; Hedestam, Gunilla B. Karlsson; Hallberg, B. Martin
Three immunizations with Novavax's protein vaccines increase antibody breadth and provide durable protection from SARS-CoV-2
NPJ VACCINES
IF6.5
2024-01-206
OAAI
Lenart, Klara; Cerveira, Rodrigo Arcoverde; Hellgren, Fredrika; Ols, Sebastian; Sheward, Daniel J.; Kim, Changil; Cagigi, Alberto; Gagne, Matthew; Davis, Brandon; Germosen, Daritza; Roy, Vicky; Alter, Galit; Letscher, Helene; Van Wassenhove, Jerome; Gros, Wesley; Gallouet, Anne-Sophie; Le Grand, Roger; Kleanthous, Harry; Guebre-Xabier, Mimi; Murrell, Ben; Patel, Nita; Glenn, Gregory; Smith, Gale; Lore, Karin
Antigen receptor stimulation induces purifying selection against pathogenic mitochondrial tRNA mutations

抗原受体刺激诱导针对致病性线粒体tRNA突变的纯化选择

JCI INSIGHT
IF6.1
2023-09-081
OA
Zhang, Jingdian; Koolmeister, Camilla; Han, Jinming; Filograna, Roberta; Hanke, Leo; Adori, Monika; Sheward, Daniel J.; Teifel, Sina; Gopalakrishna, Shreekara; Shao, Qiuya; Liu, Yong; Zhu, Keying; Harris, Robert A.; Mcinerney, Gerald; Murrell, Ben; Aoun, Mike; Baeckdahl, Liselotte; Holmdahl, Rikard; Pekalski, Marcin; Wedell, Anna; Engvall, Martin; Wredenberg, Anna; Hedestam, Gunilla B. Karlsson; Dopico, Xaquin Castro; Rorbach, Joanna
SARS-CoV-2 spike HexaPro formulated in aluminium hydroxide and administered in an accelerated vaccination schedule partially protects Syrian Hamsters against viral challenge despite low neutralizing antibody responses

SARS-CoV-2 spike HexaPro在氢氧化铝中配制并以加速疫苗接种计划施用，尽管中和抗体反应低，但仍部分保护叙利亚仓鼠免受病毒攻击

FRONTIERS IN IMMUNOLOGY
IF5.9
2023-01-233
OAAI
Christensen, Dennis; Polacek, Charlotta; Sheward, Daniel J.; Hanke, Leo; McInerney, Gerald; Murrell, Ben; Hartmann, Katrine Top; Jensen, Henrik Elvang; Zimmermann, Julie; Jungersen, Gregers; Illigen, Kristin Engelhart; Isling, Louise Krag; Fernandez-Antunez, Carlota; Ramirez, Santseharay; Bukh, Jens; Pedersen, Gabriel Kristian
Protection against SARS-CoV-2 transmission by a parenteral prime-Intranasal boost vaccine strategy

通过肠胃外prime-鼻内加强疫苗策略防止SARS-CoV-2传播

EBIOMEDICINE
IF10.8
2022-10-0118
OAAI
Christensen, Dennis; Polacek, Charlotta; Sheward, Daniel J.; Hanke, Leo; Moliner-Morro, Ainhoa; McInerney, Gerald; Murrell, Ben; Hartmann, Katrine Top; Jensen, Henrik Elvang; Jungersen, Gregers; Illigen, Kristin; Isling, Louise Krag; Jensen, Rune Fledelius; Hansen, Julia Sid; Rosenkrands, Ida; Fernandez-Antunez, Carlota; Ramirez, Santseharay; Follmann, Frank; Bukh, Jens; Pedersen, Gabriel Kristian

研究方向

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B
Ben Murrell
H 指数:48论文数:187被引数:1.8万
L
Leo Hanke
H 指数:27论文数:65被引数:2,553
G
Gerald M. McInerney
H 指数:41论文数:141被引数:1.6万
G
Gunilla B. Karlsson Hedestam
H 指数:49论文数:188被引数:7,464
C
Carolyn Williamson
H 指数:66论文数:453被引数:2.3万
C
Chang-Il Kim
H 指数:37论文数:494被引数:6,156
S
Salim S. Abdool Karim
H 指数:97论文数:736被引数:3.8万
P
Penny L. Moore
H 指数:59论文数:323被引数:1.7万
X
Xaquín Castro Dopico
H 指数:20论文数:72被引数:2,036
L
Laura Perez Vidakovics
H 指数:19论文数:36被引数:1,409