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Hideaki Ogiwara

national cancer center - japan

H指数:34

被引数:4,788

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Targeting USP8 causes synthetic lethality through degradation of FGFR2 in ARID1A-deficient ovarian clear cell carcinoma

靶向USP8通过FGFR2的降解在ARID1A缺失的卵巢透明细胞癌中引起合成致死性

NPJ PRECISION ONCOLOGY

IF8

2025-03-120

OA

Efficacy of glutathione inhibitor eprenetapopt against the vulnerability of glutathione metabolism in SMARCA4-, SMARCB1-and PBRM1-deficient cancer cells

SCIENTIFIC REPORTS

IF3.9

2024-12-280

OAAI

Targeting dependency on a paralog pair of CBP/p300 against de-repression of KREMEN2 in SMARCB1-deficient cancers

NATURE COMMUNICATIONS

IF15.7

2024-06-051

OAAI

Discovery of DS-9300: A Highly Potent, Selective, and Once-Daily Oral EP300/CBP Histone Acetyltransferase Inhibitor

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-12-2612

PRE

Response Predictive Markers and Synergistic Agents for Drug Repositioning of Statins in Ovarian Cancer

他汀类药物治疗卵巢癌的反应预测标志物和协同剂

PHARMACEUTICALS

IF4.8

2022-01-216

OAAI

Targeting p300 addiction in CBP-deficient cancers causes synthetic lethality by apoptotic cell death due to abrogation of MYC expression

MOLECULAR CANCER THERAPEUTICS

IF5.5

2017-10-020

PRE

Targeting p300 Addiction in CBP-Deficient Cancers Causes Synthetic Lethality by Apoptotic Cell Death due to Abrogation of MYC Expression

CANCER DISCOVERY

IF33.3

2016-04-03136

OAAI

Druggable oncogene fusions in lung invasive mucinous adenocarcinoma

CANCER RESEARCH

IF16.6

2015-08-010

PRE

SETDB1, HP1 and SUV39 promote repositioning of 53BP1 to extend resection during homologous recombination in G2 cells

NUCLEIC ACIDS RESEARCH

IF13.1

2015-07-2268

OAAI

The EGFR mutation status affects the relative biological effectiveness of carbon-ion beams in non-small cell lung carcinoma cells

SCIENTIFIC REPORTS

IF3.9

2015-06-1130

OAAI

The INO80 chromatin remodeling complex functions in sister chromatid cohesion

IF3.4

2014-10-2746

OAAI

Evaluation of DNA Damage Response After Carbon-Ion Beam Irradiation in p53-Mutant Cancer Cells

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

IF6.5

2014-09-010

PREAI

Proposal for a Synthetic Lethality Therapy Using the Paralog Dependence of Cancer Cells-Response

CANCER RESEARCH

IF16.6

2014-09-014

PREAI

Druggable Oncogene Fusions in Invasive Mucinous Lung Adenocarcinoma

CLINICAL CANCER RESEARCH

IF10.2

2014-06-12174

OAAI

C646, a selective small molecule inhibitor of histone acetyltransferase p300, radiosensitizes lung cancer cells by enhancing mitotic catastrophe

RADIOTHERAPY AND ONCOLOGY

IF5.3

2014-05-0168

PREAI

SWI/SNF Factors Required for Cellular Resistance to DNA Damage Include ARID1A and ARID1B and Show Interdependent Protein Stability

细胞抵抗DNA损伤所需的SWI/SNF因子包括ARID1A和ARID1B，并显示相互依赖的蛋白质稳定性

CANCER RESEARCH

IF16.6

2014-04-30159

OAAI

Fine-Tuning of DNA Damage-Dependent Ubiquitination by OTUB2 Supports the DNA Repair Pathway Choice

IF16.6

2014-02-0181

OA

A Synthetic Lethality-Based Strategy to Treat Cancers Harboring a Genetic Deficiency in the Chromatin Remodeling Factor BRG1

CANCER RESEARCH

IF16.6

2013-09-02251

OAAI

Curcumin suppresses multiple DNA damage response pathways and has potency as a sensitizer to PARP inhibitor

IF2.9

2013-07-0361

OA

Possible involvement of LKB1-AMPK signaling in non-homologous end joining

LKB1-AMPK信号可能参与非同源末端连接

IF7.3

2013-04-1531

OA