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R

Rachael A. Clark

Harvard Medical School
H指数:50
被引数:1.1万

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Spatial Transcriptomics Identifies Cytotoxic and Fibrotic Immune-Stromal Niches in Morphea and Eosinophilic Fasciitis

空间转录组学识别硬皮病和嗜酸性筋膜炎中的细胞毒性及纤维化免疫-基质微环境

Journal of Investigative Dermatology
IF5.7
2026-06-150
PRE
William J. Crisler; Kseniia S. Anufrieva; Maureen Whittelsey; Arjun Mahajan; Diogo Maia-Silva; Michael J. Martinez; Ce Gao; Jessica Liu; Oluwadamilola Oke; Maria Vazquez Machado; Rachael Rowley; Jessica Teague; Ruth Ann Vleugels; Rachael A. Clark; Kevin Wei; Avery LaChance
In morphea, cytotoxic resident memory T cells induce chronic, immunogenic endothelial cell injury via necroptosis

在硬斑病中，细胞毒性组织驻留记忆T细胞通过坏死性凋亡诱导慢性、免疫性内皮细胞损伤

JCI Insight
IF6.1
2026-05-220
PRE
Crisler, William J.; Sohail, Noor; Steuart, Samuel J.; Vazquez-Machado, Maria; Mahajan, Arjun; Whittelsey, Maureen; Pickering, Alex; Martinez, Michael J.; Hutchins, Theresa; Teague, Jessica E.; Zhan, Qian; Sui, Shannan Ho; Vleugels, Ruth Ann; Torok, Kathryn S.; Jacobe, Heidi; Clark, Rachael A.; LaChance, Avery
Nanostring Transcriptomic Analysis Highlights IL-6 Family and TGF-β Pathways in the Pathogenesis of Prurigo Nodularis

Nanostring转录组分析强调了IL-6家族和TGF-β通路在结节性痒疹发病机制中的重要性

JID Innovations
IF0
2025-11-010
OAAI
Akiska, Yagiz Matthew; Bhatt, Shrey; Vats, Kavita; Yossef, Selina M.; Gage, Davies; Shahsavari, Shahin; Born, Louis J.; Bhagchandani, Perya; Fayyad, Deena; Cornman, Hannah; Pritchard, Thomas; Teague, Jessica E.; Clark, Rachael A.; Kwatra, Madan M.; Kwatra, Shawn G.
PD-1 is requisite for skin TRM cell formation and specification by TGFβ

PD-1是tgf β 形成和规范皮肤TRM细胞的必要条件

Nature Immunology
IF27.6
2025-07-290
OA
K. Sanjana P. Devi; Eric Wang; Abhinav Jaiswal; Piotr Konieczny; Tae-Gyun Kim; Christopher J. Nirschl; Akanksha Verma; Yong Liu; Julia Milczanowski; Susan N. Christo; Luke C. Gandolfo; Karyn Haitz; Trupti D. Vardam; Pinru Wu; Sandra L. King; Sze-Wah Tse; Komal Pradhan; Xiaodong Jiang; Tian Tian; Robert C. Fuhlbrigge; Chrysalyne D. Schmults; Rachael A. Clark; Thomas S. Kupper; Gordon J. Freeman; Laura K. Mackay; Shruti Naik; Evan W. Newell; Olivier Elemento; Mayte Suarez-Farinas; Niroshana Anandasabapathy
Mast cells express IL17A, IL17F and RORC in lesional psoriatic skin, are activated before therapy and persist in high numbers in a resting state with IL-17A positivity after treatment

肥大细胞在皮损银屑病皮肤中表达IL17A、IL17F和RORC，在治疗前被激活，并在治疗后以静止状态和IL-17A阳性持续存在高数量。

Journal of Dermatological Science
IF4
2025-05-310
OAAI
Theresa Benezeder; Natalie Bordag; Johannes Woltsche; Andrea Teufelberger; Isabella Perchthaler; Wolfgang Weger; Wolfgang Salmhofer; Alexandra Gruber-Wackernagel; Clemens Painsi; Qian Zhan; Amin El-Heliebi; Magda Babina; Rachael Clark; Peter Wolf
Eosinophilic Fasciitis and Morphea Share Gene Signatures of Inflammatory Cell Death, Self-DNA Recognition, and Enhanced Jak/Signal Transducer and Activator of Transcription Signaling

嗜酸性筋膜炎和硬皮病共享炎症细胞死亡、自身DNA识别以及增强的Jak/信号转导和转录激活因子信号通路的基因特征。

Journal of Investigative Dermatology
IF5.7
2025-05-300
PRE
William J. Crisler; Rachael Rowley; Oluwadamilola Oke; Samuel J. Steuart; Maitri M. Modi; Dale L. Davis; Cynthia Chen; Lindsey Gray; Jessica E. Teague; Qian Zhan; Joseph F. Merola; Ruth Ann Vleugels; Rachael A. Clark; Avery LaChance
Spatial Proteomic Profiling Reveals Increased Levels of Cholesterol Synthesis Proteins in Psoriasis Vulgaris

空间蛋白质组学分析揭示了寻常型银屑病患者胆固醇合成蛋白水平的升高。

Journal of Investigative Dermatology
IF5.7
2025-05-220
OAAI
Line B.P. Møller; Bjørn Kromann; Sonja Kabatnik; Johanne Hatorp Hjortlund; Morten Bahrt Haulrig; Julie B.K. Sølberg; Michael Bzorek; Rachael A. Clark; Lone Skov; Matthias Mann; Marianne Bengtson Løvendorf; Beatrice Dyring-Andersen
A comparative analysis of lesional skin, sentinel flap, and mucosal biopsies in assessing acute face transplant rejection

对病灶皮肤、哨兵瓣和黏膜活检在评估急性面部移植排斥反应中的比较分析

FRONTIERS IN IMMUNOLOGY
IF5.9
2025-04-010
OA
Kauke-Navarro, Martin; Huelsboemer, Lioba; Klimitz, Felix J.; Diatta, Fortunay; Knoedler, Leonard; Knoedler, Samuel; Crisler, William J.; Brown, Stav; Lian, Christine G.; Repetto, Federico; Clark, Rachael A.; Murphy, George F.; Ko, Christine; Pomahac, Bohdan
Phototherapy Restores Deficient Type I IFN Production and Enhances Antitumor Responses in Mycosis Fungoides
JOURNAL OF INVESTIGATIVE DERMATOLOGY
IF5.7
2024-03-016
PRE
Yu, Zizi; Vieyra-Garcia, Pablo; Benezeder, Theresa; Crouch, Jack D.; Kim, Ira R.; O'Malley, John T.; Devlin, Phillip M.; Gehad, Ahmed; Zhan, Qian; Gudjonsson, Johann E.; Sarkar, Mrinal K.; Kahlenberg, J. Michelle; Gerard, Nega; Teague, Jessica E.; Kupper, Thomas S.; Leboeuf, Nicole R.; Larocca, Cecilia; Tawa, Marianne; Pomahac, Bohdan; Talbot, Simon G.; Orgill, Dennis P.; Wolf, Peter; Clark, Rachael A.

研究方向

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T
Thomas S. Kupper
H 指数:81论文数:563被引数:2.6万
J
Jessica E. Teague
H 指数:23论文数:87被引数:3,630
J
John T. O’Malley
H 指数:29论文数:117被引数:4,206
A
Ahmed Gehad
H 指数:19论文数:99被引数:3,593
E
Elizabeth L. Lowry
H 指数:7论文数:38被引数:917
B
Beatrice Dyring‐Andersen
H 指数:1论文数:3被引数:26
R
Rei Watanabe
H 指数:38论文数:261被引数:6,157
H
Harlan Robins
H 指数:71论文数:399被引数:2.5万
B
Bohdan Pomahač
H 指数:48论文数:394被引数:9,531
T
Tiago R. Matos
H 指数:19论文数:73被引数:2,102