Thomas E. Wellems - Publications, H-index & Citations

Thomas E. Wellems

National Institute for Allergy and Infectious Diseases

72H指数

245论文数

2.4W被引数

收录论文 71

发表时间

A common DNA deletion altering the 3’UTR of mdr1 is associated with reduced mefloquine susceptibility in P. vivax parasites from Cambodian patients 改变mdr1的3'UTR的常见DNA缺失与柬埔寨患者间日疟原虫的甲氟喹敏感性降低有关

Nature Communications

IF15.7

2026-01-22

OAAI

Katie Ko; Kieran Tebben; Tsarasoa Andrianinarivomanana; Agnes Orban; Janne Grünebast; Virak Eng; Rotha Eam; Nimol Khim; Lionel Brice Feufack-Donfack; Jeremy Salvador; Juliana M. Sa; Thomas E. Wellems; Dysoley Lek; Jean Popovici; David Serre

Isolation and characterization of Plasmodium falciparum blood-stage persisters by improved selection protocols using dihydroartemisinin alone

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2025-02-10

OAAI

Kiboi, Daniel; Sa, Juliana M.; Nayak, Akshaykumar; Micchelli, Chiara E.; Amin, Shuchi N.; Burbelo, Alexander G.; Abielmona, Sasha A.; Xi, Brian; Mulei, Lucia A.; Onchieku, Noah M.; Percopo, Caroline M.; Mu, Jianbing; Wellems, Thomas E.

Progressive heterogeneity of enlarged and irregularly shaped apicoplasts in Plasmodium falciparum persister blood stages after drug treatment

PNAS NEXUS

IF3.8

2024-09-24

OAAI

Micchelli, Chiara E.; Percopo, Caroline; Traver, Maria; Brzostowski, Joseph; Amin, Shuchi N.; Prigge, Sean T.; Sa, Juliana M.; Wellems, Thomas E.

Single-cell analyses of polyclonal Plasmodium vivax infections and their consequences on parasite transmission

NATURE COMMUNICATIONS

IF15.7

2024-09-02

OAAI

Hazzard, Brittany; Sa, Juliana M.; Bogale, Haikel N.; Pascini, Tales V.; Ellis, Angela C.; Amin, Shuchi; Armistead, Jennifer S.; Adams, John H.; Wellems, Thomas E.; Serre, David

Infectivity of Plasmodium parasites to Aedes aegypti and Anopheles stephensi mosquitoes maintained on blood-free meals of SkitoSnack

PARASITES & VECTORS

IF3.5

2024-07-06

OAAI

Gonzales-Wartz, Kristina K.; Sa, Juliana M.; Lee, Kevin; Gebremicale, Yonas; Deng, Bingbing; Long, Carole A.; Pascini, Tales V.; Laughinghouse, Andre; Moretz, Samuel E.; Ortega-Villa, Ana M.; Fay, Michael P.; Wellems, Thomas E.

Structure of complex III with bound antimalarial agent CK-2-68 provides insights into selective inhibition of Plasmodium cytochrome bc1 complexes

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-07-01

OAAI

Esser, Lothar; Zhou, Fei; Zeher, Allison; Wu, Weimin; Huang, Rick; Yu, Chang-An; Lane, Kristin D.; Wellems, Thomas E.; Xia, Di

Expressed var genes are found in Plasmodium falciparum subtelomeric regions

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-29

OAAI

HernandezRivas, R; Mattei, D; Sterkers, Y; Peterson, DS; Wellems, TE; Scherf, A

A Plasmodium falciparum RING Finger E3 Ubiquitin Ligase Modifies the Roles of PfMDR1 and PfCRT in Parasite Drug Responses

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2023-02-16

OAAI

Singh, Brajesh K.; Zhang, Cui; Wu, Jian; Peng, Yu-Chih; He, Xiao; Tumas, Keyla C.; Sa, Juliana M.; Lane, Kristin D.; Eastman, Richard T.; Narum, David L.; Wellems, Thomas E.; Su, Xin-zhuan

Malaria Control by Mass Drug Administration With Artemisinin Plus Piperaquine on Grande Comore Island, Union of Comoros

OPEN FORUM INFECTIOUS DISEASES

IF3.8

2023-02-14

OAAI

Deng, Changsheng; Wu, Wanting; Yuan, Yueming; Li, Guoming; Zhang, Hongying; Zheng, Shaoqin; Li, Mingqiang; Tan, Ruixiang; Wang, Yuxin; Nadia, Julie; Feng, Danhong; Li, Di; Wu, Zhibing; Xu, Qin; Li, Changqing; Wang, Zhenhua; Liang, Yuan; Doehl, Johannes S. P.; Su, Xinzhuan; Bacar, Affane; Abdallah, Kamal Said; Mohamed, Hafidhou; Mliva, Ahamada Msa; Wellems, Thomas E.; Song, Jianping

Long read single cell RNA sequencing reveals the isoform diversity of Plasmodium vivax transcripts

PLOS NEGLECTED TROPICAL DISEASES

IF3.4

2022-12-16

OAAI

Hazzard, Brittany; Sa, Juliana M.; Ellis, Angela C.; Pascini, Tales V.; Amin, Shuchi; Wellems, Thomas E.; Serre, David

5-methylcytosine modification by Plasmodium NSUN2 stabilizes mRNA and mediates the development of gametocytes

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-02-24

OAAI

Liu, Meng; Guo, Gangqiang; Qian, Pengge; Mu, Jianbing; Lu, Binbin; He, Xiaoqin; Fan, Yanting; Shang, Xiaomin; Yang, Guang; Shen, Shijun; Liu, Wenju; Wang, Liping; Gu, Liang; Mu, Quankai; Yu, Xinyu; Zhao, Yuemeng; Culleton, Richard; Cao, Jun; Jiang, Lubin; Wellems, Thomas E.; Yuan, Jing; Jiang, Cizhong; Zhang, Qingfeng

Restructured Mitochondrial-Nuclear Interaction in Plasmodium falciparum Dormancy and Persister Survival after Artemisinin Exposure

MBIO

IF4.7

2021-06-29

OAAI

V. Connelly, Sean; Manzella-Lapeira, Javier; Levine, Zoe C.; Brzostowski, Joseph; Krymskaya, Ludmila; Rahman, Rifat S.; Ellis, Angela C.; Amin, Shuchi N.; Sa, Juliana M.; Wellems, Thomas E.

Structure-switching aptamer sensors for the specific detection of piperaquine and mefloquine

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2021-03-17

PREAI

Coonahan, Erin S.; Yang, Kyung-Ae; Pecic, Stevan; De Vos, Maarten; Wellems, Thomas E.; Fay, Michael P.; Andersen, John F.; Tarning, Joel; Long, Carole A.

Transcriptional heterogeneity and tightly regulated changes in gene expression during Plasmodium berghei sporozoite development

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-03-02

OAAI

Bogale, Haikel N.; Pascini, Tales, V; Kanatani, Sachie; Sa, Juliana M.; Wellems, Thomas E.; Sinnis, Photini; Vega-Rodriguez, Joel; Serre, David

Regioisomerization of Antimalarial Drug WR99210 Explains the Inactivity of a Commercial Stock

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2020-12-16

OAAI

Remcho, T. Parks; Guggilapu, Sravanthi D.; Cruz, Phillip; Nardone, Glenn A.; Heffernan, Gavin; O'Connor, Robert D.; Bewley, Carole A.; Wellems, Thomas E.; Lane, Kristin D.

Evidence for linkage of pfmdr1, pfcrt, and pfk13 polymorphisms to lumefantrine and mefloquine susceptibilities in a Plasmodium falciparum cross

INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE

IF3.4

2020-12-01

OAAI

Windle, Sean T.; Lane, Kristin D.; Gadalla, Nahla B.; Liu, Anna; Mu, Jianbing; Caleon, Ramoncito L.; Rahman, Rifat S.; Sa, Juliana M.; Wellems, Thomas E.

'Artemisinin Resistance': Something New or Old? Something of a Misnomer?“青蒿素抵抗”: 新的还是旧的？用词不当？

Trends in Parasitology

IF6.6

2020-09-01

PREAI

Wellems, Thomas E.; Sa, Juliana M.; Su, Xin-Zhuan; Connelly, Sean, V; Ellis, Angela C.

Detection of simple and complex de novo mutations with multiple reference sequences

GENOME RESEARCH

IF5.5

2020-08-19

OAAI

Garimella, Kiran, V; Iqbal, Zamin; Krause, Michael A.; Campino, Susana; Kekre, Mihir; Drury, Eleanor; Kwiatkowski, Dominic; Sa, Juliana M.; Wellems, Thomas E.; McVean, Gil

Current vector research challenges in the greater Mekong subregion for dengue, Malaria, and Other Vector-Borne Diseases: A report from a multisectoral workshop March 2019

PLOS NEGLECTED TROPICAL DISEASES

IF3.4

2020-07-30

OAAI

Christofferson, Rebecca C.; Parker, Daniel M.; Overgaard, Hans J.; Hii, Jeffrey; Devine, Gregor; Wilcox, Bruce A.; Nam, Vu Sinh; Abubakar, Sazaly; Boyer, Sebastien; Boonnak, Kobporn; Whitehead, Stephen S.; Huy, Rekol; Rithea, Leang; Sochantha, Tho; Wellems, Thomas E.; Valenzuela, Jesus G.; Manning, Jessica E.

Plasmodium vivax chloroquine resistance links to pvcrt transcription in a genetic cross

NATURE COMMUNICATIONS

IF15.7

2019-09-20

OAAI

Sa, Juliana M.; Kaslow, Sarah R.; Barros, Roberto R. Moraes; Brazeau, Nicholas F.; Parobek, Christian M.; Tao, Dingyin; Salzman, Rebecca E.; Gibson, Tyler J.; Velmurugan, Soundarapandian; Krause, Michael A.; Melendez-Muniz, Viviana; Kite, Whitney A.; Han, Paul K.; Eastman, Richard T.; Kim, Adam; Kessler, Evan G.; Abebe, Yonas; James, Eric R.; Chakravarty, Sumana; Orr-Gonzalez, Sachy; Lambert, Lynn E.; Engels, Theresa; Thomas, Marvin L.; Fasinu, Pius S.; Serre, David; Gwadz, Robert W.; Walker, Larry; DeConti, Derrick K.; Mu, Jianbing; Bailey, Jeffrey A.; Sim, B. Kim Lee; Hoffman, Stephen L.; Fay, Michael P.; Dinglasan, Rhoel R.; Juliano, Jonathan J.; Wellems, Thomas E.

研究方向