David J. Granville - Publications, H-index & Citations

David J. Granville

university of british columbia

52H指数

216论文数

8.4K被引数

收录论文 89

发表时间

Degradomic and Transcriptomic Profiling Reveals Pleiotropic Roles of Extracellular Granzyme B in Scarring and Fibrosis 组学降解和转录组学分析揭示了细胞外颗粒酶B在瘢痕形成和纤维化中的多效作用

Matrix Biology

IF4.8

2026-09-23

OAAI

Alexandre Aubert; Anna Prudova; Jeffrey S. Tang; Jhunam Sidhu; Hans H. Adomat; Sofiia-Evelina Stretovych; Yue Shen; Katlyn C. Richardson; Daniele P. Ferrari; Michael Lane; Hongyan Zhao; Hyung-Suk Yoo; Karen Jung; Richard I. Crawford; Jayachandran N. Kizhakkedathu; Colin C. Collins; David J. Granville

Broad-spectrum bactericidal synergy of silver-cannabichromene-cannabigerol triple combinations against healthcare-associated pathogens 银-大麻色酮-大麻二酚三重组合对医院相关病原体的广谱杀菌协同作用

Journal of Applied Microbiology

IF3.2

2026-04-15

OAAI

Claudia H Dietrich; Dominique Dugourd; Sara Heidarpanah; Mark O Loveless; Manisha Dosanjh; Charles J Thompson; David J Granville; Dana M Lambert

Granzyme B contributes to subretinal fibrosis in neovascular age-related macular degeneration by modulating inflammation and epithelial-mesenchymal transition Granzyme B通过调节炎症和上皮-间质转化，对新生血管性年龄相关性黄斑变性中的视网膜下纤维化有贡献。

Journal of Neuroinflammation

IF10.1

2025-11-27

OAAI

Hyung-Suk Yoo; Harshini Chakravarthy; Jeanne Xi; Jing Cui; Zhengyuan Ai; Amir Hosseini; Jun Song; Neilan Tan; Natalie Ma; Ceres Zhou; Boaz Li; Robert Bell; Anne Haegert; Stephane Le Bihan; Myeong Jin Ju; David J. Granville; Joanne A. Matsubara

Granzyme K Contributes to Acute Itch in Psoriasis Granzyme K 参与 psoriasis 中的急性瘙痒

Journal of Dermatological Science

IF4

2025-08-18

PREAI

Aoi Hiroyasu; Beni Amatya; Daisuke Tsuruta; David J. Granville; Sho Hiroyasu

Granzyme B Mediates Syndecan-1 (CD138) Shedding in Psoriatic Keratinocytes Granzyme B 介导银屑病角质形成细胞中 Syndecan-1 (CD138) 的脱落

Journal of Investigative Dermatology

IF5.7

2025-07-17

OAAI

Alexandre Aubert; Katlyn C. Richardson; Martin Kao; Amy Liu; Jhunam Sidhu; Christopher T. Turner; Wendy A. Boivin; Richard I. Crawford; David J. Granville

Extracellular Granzyme B Mediates the Degradation of Collagen XVII in Stevens–Johnson Syndrome/Toxic Epidermal Necrolysis 细胞外颗粒酶B介导Stevens–Johnson综合征/中毒性表皮坏死松解症中胶原蛋白XVII的降解

Journal of Investigative Dermatology

IF5.7

2025-03-06

PREAI

Michael Lane; Alexandre Aubert; Anna Prudova; Faith Liu; Valerio Russo; Karen Jung; Touraj Khosravi-Hafshejani; Hongyan Zhao; Richard I. Crawford; Elizabeth Phillips; David J. Granville

Potential implications of granzyme B in keloids and hypertrophic scars through extracellular matrix remodeling and latent TGF-β activation 颗粒酶B通过细胞外基质重塑和潜在的tgf-β 激活在瘢痕疙瘩和肥厚性瘢痕中的潜在意义

FRONTIERS IN IMMUNOLOGY

IF5.9

2025-01-16

OAAI

Aubert, Alexandre; Goeres, Jenna; Liu, Amy; Kao, Martin; Richardson, Katlyn C.; Jung, Karen; Hinz, Boris; Crawford, Richard I.; Granville, David J.

Science around the world

Trends in Molecular Medicine

IF13.8

2024-12-01

PREAI

Cherubini, Alessandro; Granville, David J.; Parast, Mana M.; Su, Qi

Granzyme Bin aging and age-related pathologies

Trends in Molecular Medicine

IF13.8

2024-12-01

PREAI

Richardson, Katlyn C.; Jung, Karen; Matsubara, Joanne A.; Choy, Jonathan C.; Granville, David J.

Granzyme B cleaves tenascin-C to release its C-terminal domain in rheumatoid arthritis

JCI INSIGHT

IF6.1

2024-10-30

OAAI

Aubert, Alexandre; Liu, Amy; Kao, Martin; Goeres, Jenna; Richardson, Katlyn C.; Nierves, Lorenz; Jung, Karen; Nabai, Layla; Zhao, Hongyan; Orend, Gertraud; Krawetz, Roman; Lange, Philipp F.; Younger, Alastair; Chan, Jonathan; Granville, David J.

Exploring the role of granzyme B in subretinal fibrosis of age-related macular degeneration

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-07-18

OAAI

Gill, Karanvir; Yoo, Hyung-Suk; Chakravarthy, Harshini; Granville, David J.; Matsubara, Joanne A.

Granzyme K mediates IL-23-dependent inflammation and keratinocyte proliferation in psoriasis

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-06-05

OAAI

Richardson, Katlyn C.; Aubert, Alexandre; Turner, Christopher T.; Nabai, Layla; Hiroyasu, Sho; Pawluk, Megan A.; Cederberg, Rachel A.; Zhao, Hongyan; Jung, Karen; Burleigh, Angela; Crawford, Richard I.; Granville, David J.

Granzyme B degrades extracellular matrix and promotes inflammation and choroidal neovascularization (Mar, 10.1007/s10456-024-09909-9, 2024)

ANGIOGENESIS

IF9.2

2024-05-03

OAAI

Obasanmi, Gideon; Uppal, Manjosh; Cui, Jing Z.; Xi, Jeanne; Ju, Myeong Jin; Song, Jun; To, Eleanor; Li, Siqi; Khan, Wania; Cheng, Darian; Zhu, John; Irani, Lyden; Samad, Isa; Zhu, Julie; Yoo, Hyung-Suk; Aubert, Alexandre; Stoddard, Jonathan; Neuringer, Martha; Granville, David J.; Matsubara, Joanne A.

Granzyme serine proteases in inflammation and rheumatic diseases

NATURE REVIEWS RHEUMATOLOGY

IF32.7

2024-04-30

PREAI

Aubert, Alexandre; Jung, Karen; Hiroyasu, Sho; Pardo, Julian; Granville, David J.

Granzyme B degrades extracellular matrix and promotes inflammation and choroidal neovascularization

ANGIOGENESIS

IF9.2

2024-03-18

OAAI

Granzyme B promotes matrix metalloproteinase-1 (MMP-1) release from gingival fibroblasts in a PAR1-and Erk1/2-dependent manner: A novel role in periodontal inflammation

JOURNAL OF PERIODONTAL RESEARCH

IF3.4

2023-10-24

OAAI

Ben-Eltriki, Mohamed; Ahmadi, Amir Reza; Nakao, Yuya; Golla, Kalyan; Lakschevitz, Flavia; Haekkinen, Lari; Granville, David J.; Kim, Hugh

Granzyme B Contributes to Choroidal Neovascularization and Age-Related Macular Degeneration Through Proteolysis of Thrombospondin-1 颗粒酶B通过Thrombospondin-1蛋白水解促进脉络膜新生血管形成和年龄相关性黄斑变性

LABORATORY INVESTIGATION

IF4.2

2023-06-01

OAAI

Obasanmi, Gideon; Zeglinski, Matthew R.; Hardie, Ella; Wilhelm, Anna-Catharina; Turner, Christopher T.; Hiroyasu, Sho; Boivin, Wendy A.; Tian, Yuan; Zhao, Hongyan; To, Eleanor; Cui, Jing Z.; Xi, Jeanne; Yoo, Hyung-Suk; Uppal, Manjosh; Granville, David J.; Matsubara, Joanne A.

NK cell-derived extracellular granzyme B drives epithelial ulceration HSV-2 infection

CELL REPORTS

IF6.9

2023-04-01

OAAI

Lim, Ying Shiang; Lee, Aisha G.; Jiang, Xiaoping; Scott, Jason M.; Cofie, Adjoa; Kumar, Sandeep; Kennedy, Dania; Granville, David J.; Shin, Haina

Granzyme K contributes to endothelial microvascular damage and leakage during skin inflammation

BRITISH JOURNAL OF DERMATOLOGY

IF9.6

2022-10-23

PREAI

Turner, Christopher T.; Zeglinski, Matthew R.; Boivin, Wendy; Zhao, Hongyan; Pawluk, Megan A.; Richardson, Katlyn C.; Chandrabalan, Arundhasa; Bird, Phillip; Ramachandran, Rithwik; Sehmi, Roma; Lima, Hermenio; Gauvreau, Gail; Granville, David J.

Sulfaphenazole reduces thermal and pressure injury severity through rapid restoration of tissue perfusion

SCIENTIFIC REPORTS

IF3.9

2022-07-23

OAAI

Turner, Christopher T.; Pawluk, Megan; Bolsoni, Juliana; Zeglinski, Matthew R.; Shen, Yue; Zhao, Hongyan; Ponomarev, Tatjana; Richardson, Katlyn C.; West, Christopher R.; Papp, Anthony; Granville, David J.

研究方向