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收藏ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers
Zhang, Yi; Xie, Guojia; Lee, Ji-Eun; Zandian, Mohamad; Sudarshan, Deepthi; Estavoyer, Benjamin; Benz, Caroline; Viita, Tiina; Asgaritarghi, Golareh; Lachance, Catherine; Messmer, Clemence; Simonetti, Leandro; Sinha, Vikrant Kumar; Lambert, Jean-Philippe; Chen, Yu-Wen; Wang, Shu-Ping; Ivarsson, Ylva; Affar, El Bachir; Cote, Jacques; Ge, Kai; Kutateladze, Tatiana G.
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收藏Disruption of H3K36 methylation provokes cellular plasticity to drive aberrant glandular formation and squamous carcinogenesis
Ko, Eun Kyung; Anderson, Amy; D'souza, Carina; Zou, Jonathan; Huang, Sijia; Cho, Sohyun; Alawi, Faizan; Prouty, Stephen; Lee, Vivian; Yoon, Sora; Krick, Keegan; Horiuchi, Yoko; Ge, Kai; Seykora, John T.; Capell, Brian C.
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收藏H3K36 methyltransferase NSD1 protects against osteoarthritis through regulating chondrocyte differentiation and cartilage homeostasis
Shao, Rui; Suo, Jinlong; Zhang, Zhong; Kong, Mingxiang; Ma, Yiyang; Wen, Yang; Liu, Mengxue; Zhuang, Lenan; Ge, Kai; Bi, Qing; Zhang, Changqing; Zou, Weiguo
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收藏SAT-122: A potential first-in-class, potent, small-molecule disruptor of RAD51-BRCA2, attenuates RAD51 foci formation and tumor progression in preclinical models
Patra, S.; Pothuganti, M.; Sankeshi, V.; K, G.; Pathange, H.; S, R.; Soumyajit, K.; Viswanadha, S.
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收藏KMT2D links TGF- β signaling to noncanonical activin pathway and regulates pancreatic cancer cell plasticityKMT2D将tgf-β 信号与非典型激活素途径联系起来并调节胰腺癌细胞的可塑性
Lu, Shuang; Kim, Hong Sun; Cao, Yubo; Bedi, Karan; Zhao, Lili; Narayanan, Ishwarya Venkata; Magnuson, Brian; Gu, Yumei; Yang, Jing; Yi, Zhujun; Babaniamansour, Sepideh; Shameon, Sargis; Xu, Chang; Paulsen, Michelle T.; Qiu, Ping; Jeyarajan, Sivakumar; Ljungman, Mats; Thomas, Dafydd; Dou, Yali; Crawford, Howard; di Magliano, Marina Pasca; Ge, Kai; Yang, Bo; Shi, Jiaqi
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收藏MLL3/MLL4 methyltransferase activities control early embryonic development and embryonic stem cell differentiation in a lineage-selective manner
Xie, Guojia; Lee, Ji-Eun; Senft, Anna D.; Park, Young-Kwon; Jang, Younghoon; Chakraborty, Shreeta; Thompson, Joyce J.; McKernan, Kaitlin; Liu, Chengyu; Macfarlan, Todd S.; Rocha, Pedro P.; Peng, Weiqun; Ge, Kai
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收藏Targeted disruption of the murine Bin1/Amphiphysin II gene does not disable endocytosis but results in embryonic cardiomyopathy with aberrant myofibril formation
Muller, AJ; Baker, JF; DuHadaway, JB; Ge, K; Farmer, G; Donover, PS; Meade, R; Reid, C; Grzanna, R; Roach, AH; Shah, N; Soler, AP; Prendergast, GC
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收藏Global Analysis of H3K4 Methylation Defines MLL Family Member Targets and Points to a Role for MLL1-Mediated H3K4 Methylation in the Regulation of Transcriptional Initiation by RNA Polymerase II
Wang, Pengfei; Lin, Chengqi; Smith, Edwin R.; Guo, Hong; Sanderson, Brian W.; Wu, Min; Gogol, Madelaine; Alexander, Tara; Seidel, Christopher; Wiedemann, Leanne M.; Ge, Kai; Krumlauf, Robb; Shilatifard, Ali
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