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K

Kenneth P. Olive

Columbia University Irving Medical Center
H指数:44
被引数:1.5万

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Developmental and MAPK-responsive transcription factors regulate distinct malignant cell states and associated genetic dependencies in pancreatic cancer

发育和MAPK应答转录因子调控胰腺癌中特异的恶性细胞状态及相关遗传依赖性

Nature Genetics
IF29
2026-08-260
OA
Pasquale Laise; Mikko Turunen; Alvaro Curiel-Garcia; Lorenzo Tomassoni; H. Carlo Maurer; Ela Elyada; Bernhard Schmierer; Jeremy Worley; Jordan Kesner; Xiangtian Tan; Ester Calvo Fernandez; Yuanqing Xue; Yining Chen; Kelly Wong; Urszula N. Wasko; Somnath Tagore; Alexander L. E. Wang; Sabrina Ge; Alina C. Iuga; Aaron T. Griffin; Winston Wong; Gulam A. Manji; Mariano J. Alvarez; Faiyaz Notta; David A. Tuveson; Kenneth P. Olive; Andrea Califano
Motixafortide, cemiplimab, gemcitabine and nab-paclitaxel in metastatic pancreatic cancer: a single-arm phase 2 study with single-cell correlatives

莫替沙福肽、西米普利单抗、吉西他滨和纳布紫杉醇在转移性胰腺癌中的应用：一项含单细胞相关分析的单一队列2期研究

Nature Communications
IF15.7
2026-08-210
OA
Alexander G. Raufi; Edridge K. D’Souza; Michael S. May; Sarah Sedycias; Ilenia Pellicciotta; Samuel Pan; Shikun Wang; Carmine Palermo; Steven Sastra; Naomi Sender; Isabelle Ross; Li Li; Karan Luthria; Parin Shah; Somnath Tagore; Zachary H. Walsh; Andrew Turk; Bircan Sema; Alina Iuga; Sun Dajiang; Michael D. Kluger; Beth A. Schrope; Dane Brown; Tito Fojo; Juan-Manuel Schvartzman; Yoanna Pumpalova; Ryan H. Moy; Susan Bates; Linda Wu; Hanina Hibshoosh; Aik Choon Tan; Gary K. Schwartz; John A. Chabot; Kenneth P. Olive; Benjamin Izar; Gulam A. Manji
Combined HDAC and eIF4A inhibition: A novel epigenetic therapy for pancreatic ductal adenocarcinoma

HDAC与eIF4A联合抑制：一种新型表观遗传疗法用于治疗胰腺导管腺癌

Drug Resistance Updates
IF21.7
2025-10-040
PRE
Maryam Safari; Luigi Scotto; Agnes Basseville; Thomas Litman; Haoran Xue; Lubov Petrukhin; Ping Zhou; Helen E. Remotti; Amy Ku; Diana V. Morales; Christopher Damoci; Mingzhao Zhu; Ravikanth Maddipati; Kenneth G. Hull; Robert W. Robey; Kenneth P. Olive; Tito Fojo; Daniel Romo; Susan E. Bates
PDAC tumors from patients treated with combination MEK and autophagy inhibition reveal a treatment sensitive epithelial subtype that is enriched in murine models
CANCER RESEARCH
IF16.6
2024-09-150
PRE
Labadie, Brian W.; Obradovic, Aleksandar Z.; Ana, Sarah Sta; May, Michael; Sender, Naomi; Ross, Isabelle V.; Rodriguez-Mendez, Monica; Wasko, Urszula; Tomassoni, Lorenzo; Li, Li; Vij, Manan; Abuzaid, Sinan; Wulfkuhle, Julia; Wong, Winston; Pellicciotta, Ilenia; Izar, Benjamin; Petricoin, Emanuel F.; Tan, Aik Choon; Olive, Kenneth P.; Raufi, Alex G.; Manji, Gulam A.
Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer

胰腺癌中RAS-GTP抑制的肿瘤选择性活性

Nature
IF48.5
2024-04-080
OAAI
Urszula N. Wasko; Jingjing Jiang; Tanner C. Dalton; Alvaro Curiel-Garcia; A. Cole Edwards; Yingyun Wang; Bianca Lee; Margo Orlen; Sha Tian; Clint A. Stalnecker; Kristina Drizyte-Miller; Marie Menard; Julien Dilly; Stephen A. Sastra; Carmine F. Palermo; Marie C. Hasselluhn; Amanda R. Decker-Farrell; Stephanie Chang; Lingyan Jiang; Xing Wei; Yu C. Yang; Ciara Helland; Haley Courtney; Yevgeniy Gindin; Karl Muonio; Ruiping Zhao; Samantha B. Kemp; Cynthia Clendenin; Rina Sor; William P. Vostrejs; Priya S. Hibshman; Amber M. Amparo; Connor Hennessey; Matthew G. Rees; Melissa M. Ronan; Jennifer A. Roth; Jens Brodbeck; Lorenzo Tomassoni; Basil Bakir; Nicholas D. Socci; Laura E. Herring; Natalie K. Barker; Junning Wang; James M. Cleary; Brian M. Wolpin; John A. Chabot; Michael D. Kluger; Gulam A. Manji; Kenneth Y. Tsai; Miroslav Sekulic; Stephen M. Lagana; Andrea Califano; Elsa Quintana; Zhengping Wang; Jacqueline A. M. Smith; Matthew Holderfield; David Wildes; Scott W. Lowe; Michael A. Badgley; Andrew J. Aguirre; Robert H. Vonderheide; Ben Z. Stanger; Timour Baslan; Channing J. Der; Mallika Singh; Kenneth P. Olive
Resistance to RAS-GTP inhibition in models of pancreatic ductal adenocarcinoma arises downstream of RAS effectors

胰腺导管腺癌模型中对RAS-GTP抑制的抗性出现在RAS效应物的下游

CANCER RESEARCH
IF16.6
2024-03-220
PRE
Wasko, Urszula N.; Jiang, Jingjing; Wang, Yingyun; Tomassoni, Lorenzo; Jiang, Lingyan; Menard, Marie; Curiel-Garcia, Alvaro; Dalton, Tanner C.; Orlen, Margo; Edwards, Cole; Stalnecker, Clint; Dilly, Julien; Chang, Stephanie; Sastra, Stephen A.; Palermo, Carmine F.; Baslan, Timour; Tian, Sha; Holderfield, Matthew; Quintana, Elsa; Wang, Zhengping; Smith, Jacqueline A.; Califano, Andrea; Wildes, David; Aguirre, Andrew J.; Vonderheide, Robert H.; Stanger, Ben Z.; Lowe, Scott W.; Der, Channing J.; Singh, Mallika; Olive, Kenneth P.
An NFATc1/SMAD3/cJUN Complex Restricted to SMAD4-Deficient Pancreatic Cancer Guides Rational Therapies
GASTROENTEROLOGY
IF25.1
2024-02-012
PRE
Hasselluhn, Marie C.; Schloesser, Denise; Versemann, Lennart; Schmidt, Geske E.; Ulisse, Maria; Oschwald, Joana; Zhang, Zhe; Hamdan, Feda; Xiao, Harry; Kopp, Waltraut; Spitalieri, Jessica; Kellner, Christin; Schneider, Carolin; Reutlinger, Kristina; Nagarajan, Sankari; Steuber, Benjamin; Sastra, Stephen A.; Palermo, Carmine F.; Appelhans, Jennifer; Bohnenberger, Hanibal; Todorovic, Jovan; Kostyuchek, Irina; Stroebel, Philipp; Bockelmann, Aiko; Koenig, Alexander; Ammer-Herrmenau, Christoph; Schmidleitner, Laura; Kaulfuss, Silke; Wollnik, Bernd; Hahn, Stephan A.; Neesse, Albrecht; Singh, Shiv K.; Bastians, Holger; Reichert, Maximilian; Sax, Ulrich; Olive, Kenneth P.; Johnsen, Steven A.; Schneider, Guenter; Ellenrieder, Volker; Hessmann, Elisabeth
Tumor-selective inhibition of active RAS in pancreatic ductal adenocarcinoma
CANCER RESEARCH
IF16.6
2024-01-160
PRE
Wasko, Urszula N.; Jiang, Jingjing; Tomassoni, Lorenzo; Wang, Yingyun; Lee, Bianca; Orlen, Margo; Drizyte-Miller, Kristina; Menard, Marie; Dilly, Julien; Sastra, Steven A.; Palermo, Carmine F.; Chang, Stephanie; Aguirre, Andrew J.; Der, Channing J.; Vonderheide, Robert H.; Stanger, Ben Z.; Califano, Andrea; Singh, Mallika; Olive, Kenneth P.
CheMo4METPANC: Combination Chemotherapy ( gemcitabine and nabpaclitaxel), chemokine (C-X-C) Motif receptor 4 inhibitor (motixafortide), and immune checkpoint blockade (cemiplimab) in METastatic treatment-naive PANCreatic adenocarcinoma
CANCER RESEARCH
IF16.6
2024-01-160
PRE
Manji, Gulam A.; May, Michael; Chalabi, Morteza Hajkarim; Pellicciotta, Ilenia; Ana, Sarah I. Sta; Sender, Naomi; Pan, Samuel S.; Ross, Isabelle V.; Olive, Kenneth P.; Wang, Shikun; Izar, Benjamin; White, Ruth A.; Bates, Susan E.; Raufi, Alexander G.
Tumor Explants Elucidate a Cascade of Paracrine SHH, WNT, and VEGF Signals Driving Pancreatic Cancer Angiosuppression

肿瘤外植体阐明了驱动胰腺癌血管抑制的旁分泌SHH，WNT和VEGF信号的级联

CANCER DISCOVERY
IF33.3
2023-11-144
OA
Hasselluhn, Marie C.; Decker-Farrell, Amanda R.; Vlahos, Lukas; Thomas, Dafydd H.; Curiel-Garcia, Alvaro; Maurer, H. Carlo; Wasko, Urszula N.; Tomassoni, Lorenzo; Sastra, Stephen A.; Palermo, Carmine F.; Dalton, Tanner C.; Ma, Alice; Li, Fangda; Tolosa, Ezequiel J.; Hibshoosh, Hanina; Fernandez-Zapico, Martin E.; Muir, Alexander; Califano, Andrea; Olive, Kenneth P.
A Transcriptome-Based Precision Oncology Platform for Patient-Therapy Alignment in a Diverse Set of Treatment-Resistant Malignancies
CANCER DISCOVERY
IF33.3
2023-04-169
OA
Mundi, Prabhjot S.; Cruz, Filemon S. Dela; Grunn, Adina; Diolaiti, Daniel; Mauguen, Audrey; Rainey, Allison R.; Guillan, Kristina; Siddiquee, Armaan; You, Daoqi; Realubit, Ronald; Karan, Charles; Ortiz, Michael V.; Douglass, Eugene F.; Accordino, Melissa; Mistretta, Suzanne; Brogan, Frances; Bruce, Jeffrey N.; Caescu, Cristina I.; Carvajal, Richard D.; Crew, Katherine D.; Decastro, Guarionex; Heaney, Mark; Henick, Brian S.; Hershman, Dawn L.; Hou, June Y.; Iwamoto, Fabio M.; Jurcic, Joseph G.; Kiran, Ravi P.; Kluger, Michael D.; Kreisl, Teri; Lamanna, Nicole; Lassman, Andrew B.; Lim, Emerson A.; Manji, Gulam A.; Mckhann, Guy M.; Mckiernan, James M.; Neugut, Alfred I.; Olive, Kenneth P.; Rosenblat, Todd; Schwartz, Gary K.; Shu, Catherine A.; Sisti, Michael B.; Tergas, Ana; Vattakalam, Reena M.; Welch, Mary; Wenske, Sven; Wright, Jason D.; Canoll, Peter; Hibshoosh, Hanina; Kalinsky, Kevin; Aburi, Mahalaxmi; Sims, Peter A.; Alvarez, Mariano J.; Kung, Andrew L.; Califano, Andrea

研究方向

暂未获取到该数据
C
Carmine F. Palermo
H 指数:13论文数:151被引数:4,003
S
Stephen A. Sastra
H 指数:19论文数:151被引数:4,790
H
H. Carlo Maurer
H 指数:24论文数:252被引数:3,750
A
Andrea Califano
H 指数:96论文数:1,072被引数:5.4万
U
Urszula N. Wasko
H 指数:7论文数:93被引数:329
M
Marie C. Hasselluhn
H 指数:9论文数:99被引数:336
T
Timothy C. Wang
H 指数:128论文数:1,165被引数:9.0万
L
Lorenzo Tomassoni
H 指数:8论文数:110被引数:419
T
Tanner C. Dalton
H 指数:6论文数:107被引数:569
Á
Álvaro Curiel‐García
H 指数:7论文数:116被引数:382