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R

Roger Le Grand

université paris-saclay and inserm and cea

57H指数
488论文数
1.3W被引数
收录论文 191
发表时间
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OVX033 nucleocapsid vaccine induces cross-reactive T cells and boosts memory in SARS-CoV-2-primed non-human primatesOVX033核衣壳疫苗诱导交叉反应性T细胞并增强SARS-CoV-2预免疫非人灵长类动物的记忆
errCommunications Biology
IF5.1
err2026-09-22
err0
errOAAI
errRomain Marlin; Charlotte Primard; Anne-Sophie Gallouët; Alice Indalecio; Nathalie Dereuddre-Bosquet; Delphine Nourissat; Mariangela Cavarelli; Séverine Valsesia; Mélanie Robin; Wesley Gros; Sebastien Langlois; Laetitia Bossevot; Julie Morin; Alexandre Calcei; Judith Del Campo; Julien Bouley; Francis Relouzat; Delphine Guyon-Gellin; Roger Le Grand; Florence Nicolas
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err收藏
Constitutive natural killer cell features associated with post-treatment control of SIV infection in the pVISCONTI studypVISCONTI研究中与治疗后控制SIV感染相关的固有自然杀伤细胞特征
errNature Communications
IF15.7
err2026-08-22
err0
errOAAI
errAnaïs Chapel; Luis Romero-Martín; Caroline Passaes; Valérie Monceaux; Stevenn Volant; Delphine Desjardins; Adeline Melard; Annie David; Nathalie Dereuddre-Bosquet; Christine Rouzioux; Véronique Avettand-Fenoel; Michaela Müller-Trutwin; Roger Le Grand; Asier Sáez-Cirión
err分享
err收藏
Dual Blockade of LILRB1 and LILRB2 Enhances Antiviral Immune Responses in SIV Infection
errAdvanced Science
IF14.1
err2026-07-31
err0
errOAAI
errFlorian Meurisse; Sixtine Coindre; Anne Wijkhuisen; Romain Marlin; Laure Fournier Le Ray; Juliette Pons; Melyssa Yaugel-Novoa; Véronique Avettand-Fenoel; Laurent Abi-Rached; Anne-Sophie Gallouet; Francis Relouzat; Mael Gourves; Asier Saez-Cirion; Hisashi Arase; Gerard Zurawski; Sandra Zurawski; Nathalie Dereuddre-Bosquet; Roger Le Grand; Stéphanie Simon; Olivier Lambotte; Benoit Favier
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Limited tissue persistence confirms attenuation of live-attenuated chikungunya vaccine VLA1553 in non-human primates有限组织持久性证实减毒活疫苗VLA1553在非人灵长类动物中的减毒效果
errnpj Vaccines
IF6.5
err2026-07-23
err0
errOAAI
errPierre Roques; Andrea Fritzer; Nathalie Dereuddre-Bosquet; Laetitia Bossevot; Quentin Pascal; Roger Le Grand; Urban Lundberg; Andreas Meinke
err分享
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Favipiravir tissue distribution and inhibitory quotients in preclinical models: towards a pipeline for evidence-based antiviral repurposing法匹拉韦的组织分布和抑制倍数在临床前模型中：迈向循证抗病毒药物重定位的流程
errJournal of Antimicrobial Chemotherapy
IF3.6
err2026-07-03
err0
errOAAI
errPaul-Rémi Petit; Franck Touret; Jean-Sélim Driouich; Albert Paré; Xavier de Lamballerie; Romain Marlin; Vanessa Contreras; Francis Relouzat; Anne-Sophie Gallouët; Quentin Pascal; Jérémie Guedj; Roger Le Grand; Antoine Nougairède; Caroline Solas
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Post-treatment SIV control is associated with specific features of viral persistence before and after treatment interruption治疗后SIV控制与治疗前及治疗中断后的病毒持续存在特征相关
errNature Communications
IF15.7
err2026-02-27
err0
errOAAI
errCaroline Charre; Adeline Melard; Antoine Chaillon; Elise Gardiennet; Delphine Desjardins; Caroline Passaes; Antoine Millet; Marine Fillion; Nastasia Dimant; Valérie Monceaux; Nathalie Dereuddre-Bosquet; Olivier Lambotte; Michaela Muller-Trutwin; Christine Rouzioux; Roger Le Grand; Asier Saez- Cirion; Véronique Avettand-Fenoel
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Induction of HIV-1-specific antibody-mediated effector functions by native-like envelope trimers in humans人源天然样-envelope三聚体诱导HIV-1特异性抗体介导的效应功能
errPLOS PATHOGENS
IF4.9
err2025-10-01
err1
PREAI
errGrobben, Marloes; Reiss, Emma I. M. M.; Schriek, Angela I.; van der Straten, Karlijn; Dereuddre-Bosquet, Nathalie; Maisonnasse, Pauline; Rooker, Alex; Yu, Chunhao; Tejjani, Khadija; Tolazzi, Monica; Sliepen, Kwinten; Levai, Reka Felfodine; Farsang, Attila; Le Grand, Roger; Scarlatti, Gabriella; Shattock, Robin J.; de Taeye, Steven W.; de Bree, Godelieve J.; Sanders, Rogier W.; van Gils, Marit J.
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Efficacy of modified-vaccinia Ankara vaccine as pre- and post-exposure prophylaxis against monkeypox sexual transmission in non-human primate model改良型安卡拉痘苗疫苗作为非人灵长类模型中针对猴痘性传播的预暴露和后暴露预防的疗效
errNature Communications
IF15.7
err2025-08-07
err0
errOAAI
errCécile Herate; Audrey Ferrier-Rembert; Francis Relouzat; Anne-Sophie Gallouët; Quentin Pascal; Hélène Letscher; Mariangela Cavarelli; Nathalie Dereuddre-Bosquet; Wesley Gros; Benoit Delache; Sébastien Langlois; Hawa Timera; Fanny Jarjaval; Laetitia Bossevot; Camille Ludot; Catherine Brua; Maxence Lechemia; Olivier Ferraris; Nathalie Silvestre; Roger Le Grand; Jean-Nicolas Tournier
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Positron emission tomography-based comparison of methods for exposing macaques to respiratory pathogens基于正电子发射断层扫描技术的灵长类动物暴露于呼吸道病原体的方法比较
errJournal of Aerosol Science
IF2.9
err2025-07-05
err0
PREAI
errBenoît Delache; Anaïs-Rachel Garnier; Cécile Herate; Francis Relouzat; Pierre Lê-Bury; Julien Lemaitre; Asma Berriche; Quentin Sconosciuti; Eleana Navarre; Noémie Verguet; Justina Creppy; Olivier Gorgé; Jean-Nicolas Tournier; Frédéric Ducancel; Laurent Vecellio; Roger Le Grand; Thibaut Naninck
err分享
err收藏
Virus-Induced Cellular Senescence Causes Pulmonary Sequelae Post-Influenza Infection病毒诱导的细胞衰老导致流感感染后肺部后遗症
errAging Cell
IF7.1
err2025-06-20
err0
errOAAI
errLarissa Lipskaia; Lou Delval; Valentin Sencio; Emmanuelle Born; Séverine Heumel; Amal Houssaini; Clara Valentin; Stefano Raviola; Lucie Deruyter; Fabiola Silva Angulo; Vincent Gros; Elisabeth Marcos; Shariq Abid; Mira Goekyildirim; Vanessa Contreras; Jean Michel Flaman; Roger Le Grand; Ronan Le Goffic; David Bernard; Serge Adnot; François Trottein
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Inactivated Viral Vaccine BBV87 Protects Against Chikungunya Virus Challenge in a Non-Human Primate Model灭活病毒疫苗BBV87在非人灵长类动物模型中抵抗登革热病毒攻击的保护作用
errVIRUSES-BASEL
IF3.5
err2025-04-10
err0
errOAAI
errKempster, Sarah L.; Ferguson, Deborah; Ham, Claire; Hall, Joanna; Jenkins, Adrian; Giles, Elaine; Priestnall, Simon L.; Suarez-Bonnet, Alejandro; Roques, Pierre; Le Grand, Roger; Kandaswamy, Sumathy; Sahastrabuddhe, Sushant; Hernandez, Libia Milena; Chuasuwan, Sunee; Ahn, Hyeon Seon; Kim, Deok Ryun; Wartel, Anh; Zellweger, Raphael M.; Berry, Neil; Almond, Neil
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RBD-depleted SARS-CoV-2 spike generates protective immunity in cynomolgus macaquesRBD缺失的SARS-CoV-2刺突蛋白在食蟹猴中产生保护性免疫
errNPJ VACCINES
IF6.5
err2025-03-30
err0
errOAAI
errLetscher, Helene; Guilligay, Delphine; Effantin, Gregory; Amen, Axelle; Sulbaran, Guidenn; Burger, Judith A.; Bossevot, Laetitia; Junges, Laura; Leonec, Marco; Morin, Julie; Van Tilbeurgh, Matthieu; Herate, Cecile; Gallouet, Anne-Sophie; Relouzat, Francis; van der Werf, Sylvie; Cavarelli, Mariangela; Dereuddre-Bosquet, Nathalie; van Gils, Marit J.; Sanders, Rogier W.; Poignard, Pascal; Le Grand, Roger; Weissenhorn, Winfried
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Whole-body visualization of SARS-CoV-2 biodistribution in vivo by immunoPET imaging in non-human primates通过免疫PET成像对非人灵长类动物体内SARS-CoV-2生物分布进行全身可视化
errNATURE COMMUNICATIONS
IF15.7
err2025-03-21
err0
errOAAI
errDetrille, Alexandra; Huvelle, Steve; van Gils, Marit J.; Geara, Tatiana; Pascal, Quentin; Snitselaar, Jonne; Bossevot, Laetitia; Cavarelli, Mariangela; Dereuddre-Bosquet, Nathalie; Relouzat, Francis; Contreras, Vanessa; Chapon, Catherine; Caille, Fabien; Sanders, Rogier W.; Le Grand, Roger; Naninck, Thibaut
err分享
err收藏
MINCLE and TLR9 agonists synergize to induce Th1/Th17 vaccine memory and mucosal recall in mice and non-human primates
errNATURE COMMUNICATIONS
IF15.7
err2024-10-17
err0
errOAAI
errWoodworth, Joshua S.; Contreras, Vanessa; Christensen, Dennis; Naninck, Thibaut; Kahlaoui, Nidhal; Gallouet, Anne-Sophie; Langlois, Sebastien; Burban, Emma; Joly, Candie; Gros, Wesley; Dereuddre-Bosquet, Nathalie; Morin, Julie; Olsen, Ming Liu; Rosenkrands, Ida; Stein, Ann-Kathrin; Wood, Grith Kroyer; Follmann, Frank; Lindenstrom, Thomas; Hu, Tu; Le Grand, Roger; Pedersen, Gabriel Kristian; Mortensen, Rasmus
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err收藏
Improved Automated Radiosynthesis of [18F]Dolutegravir: Toward Clinical Applications
errACS OMEGA
IF4.3
err2024-09-27
err0
errOAAI
errHuvelle, Steve; Pinon, Antoine; Coulon, Christine; Bonasera, Thomas; Chapon, Catherine; Naninck, Thibaut; Le Grand, Roger; Parry, Chris M.; Kuhnast, Bertrand; Caille, Fabien
err分享
err收藏
Seminal plasma inhibits Chlamydia trachomatis infection in vitro, and may have consequences on mucosal immunity
errSCIENTIFIC REPORTS
IF3.9
err2024-09-09
err1
errOAAI
errReot, Louis; Adapen, Cindy; Cannou, Claude; Nunez, Natalia; Lakoum, Sabrine; Pimienta, Camille; Lacroix, Laetitia; Binois, Olivier; Frydman, Nelly; Nugeyre, Marie-Therese; Le Grand, Roger; Menu, Elisabeth
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Multiple Mechanisms of Action of Sulfodyne®, a Natural Antioxidant, against Pathogenic Effects of SARS-CoV-2 Infection
errANTIOXIDANTS
IF6.6
err2024-09-04
err0
errOAAI
errRomeo, Paul-Henri; Conquet, Laurine; Messiaen, Sebastien; Pascal, Quentin; Moreno, Stephanie G.; Bravard, Anne; Bernardino-Sgherri, Jacqueline; Dereuddre-Bosquet, Nathalie; Montagutelli, Xavier; Le Grand, Roger; Petit, Vanessa; Ferri, Federica
err分享
err收藏
Fetal Zika virus inoculation in macaques revealed control of the fetal viral load during pregnancy
errVIROLOGY JOURNAL
IF3.8
err2024-09-03
err0
PREAI
errEgloff, Charles; Fovet, Claire-Maelle; Denis, Jessica; Pascal, Quentin; Bossevot, Laetitia; Luccantoni, Sophie; Leonec, Marco; Dereuddre-Bosquet, Nathalie; Leparc-Goffart, Isabelle; Le Grand, Roger; Durand, Guillaume Andre; Badaut, Cyril; Picone, Olivier; Roques, Pierre
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Specific imaging of CD8+T-Cell dynamics with a nanobody radiotracer against human CD8β使用针对人类CD8β 的纳米体放射性示踪剂对CD8 T细胞动力学进行特异性成像
errEuropean Journal of Nuclear Medicine and Molecular Imaging
IF7.6
err2024-09-02
err2
errOAAI
errDe Groof, Timo W. M.; Lauwers, Yoline; De Pauw, Tessa; Saxena, Mohit; Vincke, Cecile; Van Craenenbroeck, Jolien; Chapon, Catherine; Le Grand, Roger; Raes, Geert; Naninck, Thibaut; Van Ginderachter, Jo A.; Devoogdt, Nick
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err收藏
Multimodal mucosal and systemic immune characterization of a non-human primate trachoma model highlights the critical role of local immunity during acute phase disease非人类灵长类动物沙眼模型的多模式粘膜和全身免疫表征突出了局部免疫在急性期疾病中的关键作用
errPLOS NEGLECTED TROPICAL DISEASES
IF3.4
err2024-08-02
err0
errOAAI
errPaulet, Elodie; Contreras, Vanessa; Galhaut, Mathilde; Rosenkrands, Ida; Holland, Martin; Burton, Matthew; Dietrich, Jes; Gallouet, Anne-Sophie; Bosquet, Nathalie; Relouzat, Francis; Langlois, Sebastien; Follmann, Frank; Le Grand, Roger; Labetoulle, Marc; Rousseau, Antoine
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研究方向

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合作学者
合作期刊
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