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G

Graham J. Britton

Icahn School of Medicine at Mount Sinai
H指数:18
被引数:4,681

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Combining genotoxic gut bacterial strains increases tumor burden and accelerates onset in a germ-free mouse model of colon carcinogenesis

将具有基因毒性的肠道细菌菌株结合会增加无菌小鼠结肠癌模型中的肿瘤负担并加速其发生

Cell Reports
IF6.9
2026-07-011
PRE
Plitt, Tamar; Piessevaux, Alix; Rajpal, Urvija; Fischer, Jeremy; Spindler, Matthew P.; Ruprecht, Constantin; Li, Zhihua; Mogno, Ilaria; Yang, Ye; Desch, A. Nicole; Chu, Gerald; Jiang, Zhengyu; Wang, Jianyao; Gevers, Dirk; Pocalyko, David; Geis, Abby L.; Jobin, Christian; Bachman, Kurtis E.; Sears, Cynthia L.; Britton, Graham J.; Mateo, Lani R. San; Faith, Jeremiah J.
15-strain live biotherapeutic product or same donor fecal microbiota transplant for recurrent Clostridioides difficile infection: a randomized phase 1b trial

15株活生物治疗产品或相同供体粪便微生物移植治疗复发性艰难梭菌感染: 一项随机1b期试验

Nature Medicine
IF50
2026-06-020
PRE
Lukas Bethlehem; Lorenza Bartu; Gina Marke; Phyu Mar; Sari Feldman; Joseph Eggers; Constantin Ruprecht; Graham J. Britton; Varun Aggarwala; Gerold Bongers; Zhihua Li; Nancy Yang; Elizabeth L. Hohmann; Ilaria Mogno; Jeremiah J. Faith; Ari Grinspan
Baseline colitogenicity and acute perturbations of gut microbiota in immunotherapy-related colitis
JOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
2024-12-120
OAAI
Shang, Joan; Del Valle, Diane Marie; Britton, Graham J.; Mead, K. R.; Rajpal, Urvija; Chen-Liaw, Alice; Mogno, Ilaria; Li, Zhihua; Menon, Rajita; Gonzalez-Kozlova, Edgar; Elkrief, Arielle; Peled, Jonathan U.; Gonsalves, Tina Ruth; Shah, Neil J.; Postow, Michael; Colombel, Jean-Frederic; Gnjatic, Sacha; Faleck, David M.; Faith, Jeremiah J.
Alterations in the gut microbiome implicate key taxa and metabolic pathways across inflammatory arthritis phenotypes

肠道微生物组的改变涉及炎症性关节炎表型的关键分类单元和代谢途径

SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2023-07-2618
OA
Thompson, Kelsey N. S.; Bonham, Kevin S. E.; Ilott, Nicholas E. J.; Britton, Graham J.; Colmenero, Paula J.; Bullers, Samuel J. J.; McIver, Lauren J.; Ma, Siyuan H.; Nguyen, Long H.; Filer, Andrew; Brough, India; Pearson, Claire; Moussa, Caroline; Kumar, Vinod H.; Lam, Lilian H. A.; Jackson, Matthew A.; Pawluk, April; Kiriakidis, Serafim R.; Taylor, Peter C.; Wedderburn, Lucy R. P.; Marsden, Brian R.; Young, Stephen P. J.; Littman, Dan R. G.; Faith, Jeremiah J.; Pratt, Arthur G.; Bowness, Paul; Raza, Karim; Powrie, Fiona; Huttenhower, Curtis
Intestinal Host Response to SARS-CoV-2 Infection and COVID-19 Outcomes in Patients With Gastrointestinal Symptoms
GASTROENTEROLOGY
IF25.1
2021-06-01114
OA
Livanos, Alexandra E.; Jha, Divya; Cossarini, Francesca; Gonzalez-Reiche, Ana S.; Tokuyama, Minami; Aydillo, Teresa; Parigi, Tommaso L.; Ladinsky, Mark S.; Ramos, Irene; Dunleavy, Katie; Lee, Brian; Dixon, Rebekah E.; Chen, Steven T.; Martinez-Delgado, Gustavo; Nagula, Satish; Bruce, Emily A.; Ko, Huaibin M.; Glicksberg, Benjamin S.; Nadkarni, Girish; Pujadas, Elisabet; Reidy, Jason; Naymagon, Steven; Grinspan, Ari; Ahmad, Jawad; Tankelevich, Michael; Bram, Yaron; Gordon, Ronald; Sharma, Keshav; Houldsworth, Jane; Britton, Graham J.; Chen-Liaw, Alice; Spindler, Matthew P.; Plitt, Tamar; Wang, Pei; Cerutti, Andrea; Faith, Jeremiah J.; Colombel, Jean-Frederic; Kenigsberg, Ephraim; Argmann, Carmen; Merad, Miriam; Gnjatic, Sacha; Harpaz, Noam; Danese, Silvio; Cordon-Cardo, Carlos; Rahman, Adeeb; Schwartz, Robert E.; Kumta, Nikhil A.; Aghemo, Alessio; Bjorkman, Pamela J.; Petralia, Francesca; van Bakel, Harm; Garcia-Sastre, Adolfo; Mehandru, Saurabh
A LAT-Based Signaling Complex in the Immunological Synapse as Determined with Live Cell Imaging Is Less Stable in T Cells with Regulatory Capability

通过活细胞成像确定的免疫突触中基于LAT的信号传导复合物在具有调节能力的T细胞中不太稳定

CELLS
IF5.2
2021-02-171
OAAI
Li, Yikui; Tunbridge, Helen M.; Britton, Graham J.; Hill, Elaine V.; Sinai, Parisa; Cirillo, Silvia; Thompson, Clare; Fallah-Arani, Farnaz; Dovedi, Simon J.; Wraith, David C.; Wulfing, Christoph
Defined microbiota transplant restores Th17/RORγt+ regulatory T cell balance in mice colonized with inflammatory bowel disease microbiotas

定义的微生物群移植可恢复炎症性肠病微生物定植小鼠的Th17/ror γ T调节性T细胞平衡

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2020-08-1871
OAAI
Britton, Graham J.; Contijoch, Eduardo J.; Spindler, Matthew P.; Aggarwala, Varun; Dogan, Belgin; Bongers, Gerold; San Mateo, Lani; Baltus, Andrew; Das, Anuk; Gevers, Dirk; Borody, Thomas J.; Kaakoush, Nadeem O.; Kamm, Michael A.; Mitchell, Hazel; Paramsothy, Sudarshan; Clemente, Jose C.; Colombel, Jean-Frederic; Simpson, Kenneth W.; Dubinsky, Marla C.; Grinspan, Ari; Faith, Jeremiah J.
Immunology of COVID-19: Current State of the Science

新型冠状病毒肺炎免疫学: 科学的现状

IMMUNITY
IF26.3
2020-06-011.2K
OAAI
Vabret, Nicolas; Britton, Graham J.; Gruber, Conor; Hegde, Samarth; Kim, Joel; Kuksin, Maria; Levantovsky, Rachel; Malle, Louise; Moreira, Alvaro; Park, Matthew D.; Pia, Luisanna; Risson, Emma; Saffern, Miriam; Salome, Berengere; Selvan, Myvizhi Esai; Spindler, Matthew P.; Tan, Jessica; van der Heide, Verena; Gregory, Jill K.; Alexandropoulos, Konstantina; Bhardwaj, Nina; Brown, Brian D.; Greenbaum, Benjamin; Gumus, Zeynep H.; Homann, Dirk; Horowitz, Amir; Kamphorst, Alice O.; de Lafaille, Maria A. Curotto; Mehandru, Saurabh; Merad, Miriam; Samstein, Robert M.
Gut microbiota density influences host physiology and is shaped by host and microbial factors
ELIFE
IF0
2019-01-22130
OAAI
Contijoch, Eduardo J.; Britton, Graham J.; Yang, Chao; Mogno, Ilaria; Li, Zhihua; Ng, Ruby; Llewellyn, Sean R.; Hira, Sheela; Johnson, Crystal; Rabinowitz, Keren M.; Barkan, Revital; Dotan, Iris; Hirten, Robert P.; Fu, Shih-Chen; Luo, Yuying; Yang, Nancy; Luong, Tramy; Labrias, Philippe R.; Lira, Sergio; Peter, Inga; Grinspan, Ari; Clemente, Jose C.; Kosoy, Roman; Kim-Schulze, Seunghee; Qin, Xiaochen; Castillo, Anabella; Hurley, Amanda; Atreja, Ashish; Rogers, Jason; Fasihuddin, Farah; Saliaj, Merjona; Nolan, Amy; Reyes-Mercedes, Pamela; Rodriguez, Carina; Aly, Sarah; Santa-Cruz, Kenneth; Peters, Lauren; Suarez-Farinas, Mayte; Huang, Ruiqi; Hao, Ke; Zhu, Jun; Zhang, Bin; Losic, Bojan; Irizar, Haritz; Song, Won-Min; Di Narzo, Antonio; Wang, Wenhui; Cohen, Benjamin L.; DiMaio, Christopher; Greenwald, David; Itzkowitz, Steven; Lucas, Aimee; Marion, James; Maser, Elana; Ungaro, Ryan; Naymagon, Steven; Novak, Joshua; Shah, Brijen; Ullman, Thomas; Rubin, Peter; George, James; Legnani, Peter; Telesco, Shannon E.; Friedman, Joshua R.; Brodmerkel, Carrie; Plevy, Scott; Cho, Judy H.; Colombel, Jean-Frederic; Schadt, Eric E.; Argmann, Carmen; Dubinsky, Marla; Kasarskis, Andrew; Sands, Bruce; Faith, Jeremiah J.
Microbiotas from Humans with Inflammatory Bowel Disease Alter the Balance of Gut Th17 and RORγt+ Regulatory T Cells and Exacerbate Colitis in Mice
IMMUNITY
IF26.3
2019-01-01373
OAAI
Britton, Graham J.; Contijoch, Eduardo J.; Mogno, Ilaria; Vennaro, Olivia H.; Llewellyn, Sean R.; Ng, Ruby; Li, Zhihua; Mortha, Arthur; Merad, Miriam; Das, Anuk; Gevers, Dirk; McGovern, Dermot P. B.; Singh, Namita; Braun, Jonathan; Jacobs, Jonathan P.; Clemente, Jose C.; Grinspan, Ari; Sands, Bruce E.; Colombel, Jean-Frederic; Dubinsky, Marla C.; Faith, Jeremiah J.
The role of individual protein kinase C isoforms in mouse mast cell function and their targeting by the immunomodulatory parasitic worm product, ES-62

单个蛋白激酶C同工型在小鼠肥大细胞功能中的作用及其免疫调节寄生蠕虫产物ES-62的靶向作用

IMMUNOLOGY LETTERS
IF2.8
2015-11-0115
OAAI
Bell, Kara S.; Al-Riyami, Lamyaa; Lumb, Felicity E.; Britton, Graham J.; Poole, Alastair W.; Williams, Christopher M.; Braun, Ursula; Leitges, Michael; Harnett, Margaret M.; Harnett, William

研究方向

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J
Jeremiah J. Faith
H 指数:53论文数:162被引数:2.8万
D
David C. Wraith
H 指数:62论文数:270被引数:1.4万
J
Jean‐Frédéric Colombel
H 指数:139论文数:1,358被引数:9.6万
M
Matthew P. Spindler
H 指数:13论文数:23被引数:2,435
A
Ari Grinspan
H 指数:25论文数:110被引数:2,806
I
Ilaria Mogno
H 指数:21论文数:52被引数:4,797
E
Eduardo J. Contijoch
H 指数:8论文数:18被引数:1,977
M
Miriam Mérad
H 指数:135论文数:774被引数:9.3万
J
José C. Clemente
H 指数:74论文数:270被引数:8.4万
B
Bronwen R. Burton
H 指数:11论文数:27被引数:859