Wu, Chuanyan; Borne, Yan; Gao, Rui; Rodriguez, Maykel Lopez; Roell, William C.; Wilson, Jonathan M.; Regmi, Ajit; Luan, Cheng; Aly, Dina Mansour; Peter, Andreas; Machann, Juergen; Staiger, Harald; Fritsche, Andreas; Birkenfeld, Andreas L.; Tao, Rongya; Wagner, Robert; Canouil, Mickael; Hong, Mun-Gwan; Schwenk, Jochen M.; Ahlqvist, Emma; Kaikkonen, Minna U.; Nilsson, Peter; Shore, Angela C.; Khan, Faisel; Natali, Andrea; Melander, Olle; Orho-Melander, Marju; Nilsson, Jan; Haering, Hans-Ulrich; Renstrom, Erik; Wollheim, Claes B.; Engstrom, Gunnar; Weng, Jianping; Pearson, Ewan R.; Franks, Paul W.; White, Morris F.; Duffin, Kevin L.; Vaag, Allan Arthur; Laakso, Markku; Stefan, Norbert; Groop, Leif; De Marinis, Yang

Dopamine regulates pancreatic glucagon and insulin secretion via adrenergic and dopaminergic receptors

TRANSLATIONAL PSYCHIATRY

IF6.2

2021-02-1668

OAAI

Augmented mitochondrial energy metabolism is an early response to chronic glucose stress in human pancreatic beta cells

DIABETOLOGIA

IF10.2

2020-09-2225

OAAI

Potential Protection Against Type 2 Diabetes in Obesity Through Lower CD36 Expression and Improved Exocytosis in β-Cells

DIABETES

IF7.5

2020-03-2042

OAAI

Increased uptake of oxLDL does not exert lipotoxic effects in insulin-secreting cells

JOURNAL OF MOLECULAR ENDOCRINOLOGY

IF3.8

2019-05-013

Preserving Insulin Secretion in Diabetes by Inhibiting VDAC1 Overexpression and Surface Translocation in β Cells

通过抑制 β 细胞中VDAC1的过表达和表面易位来维持糖尿病的胰岛素分泌

CELL METABOLISM

IF30.9

2019-01-01121

OAAI

Silencing of the FTO gene inhibits insulin secretion: An in vitro study using GRINCH cells

MOLECULAR AND CELLULAR ENDOCRINOLOGY

IF3.6

2018-09-0130

OAAI

Sulforaphane improves disrupted ER-mitochondria interactions and suppresses exaggerated hepatic glucose production

MOLECULAR AND CELLULAR ENDOCRINOLOGY

IF3.6

2018-02-0136

PREAI

Glutamine-Elicited Secretion of Glucagon-Like Peptide 1 Is Governed by an Activated Glutamate Dehydrogenase

DIABETES

IF7.5

2017-12-1120

OAAI

Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes

来自器官供体和胰腺切除患者的IMIDIA生物库的系统生物学定义了2型糖尿病患者胰岛的新型转录组学特征

DIABETOLOGIA

IF10.2

2017-11-28119

OAAI

Solimena, Michele; Schulte, Anke M.; Marselli, Lorella; Ehehalt, Florian; Richter, Daniela; Kleeberg, Manuela; Mziaut, Hassan; Knoch, Klaus-Peter; Parnis, Julia; Bugliani, Marco; Siddiq, Afshan; Joerns, Anne; Burdet, Frederic; Liechti, Robin; Suleiman, Mara; Margerie, Daniel; Syed, Farooq; Distler, Marius; Gruetzmann, Robert; Petretto, Enrico; Moreno-Moral, Aida; Wegbrod, Carolin; Soenmez, Anke; Pfriem, Katja; Friedrich, Anne; Meinel, Joern; Wollheim, Claes B.; Baretton, Gustavo B.; Scharfmann, Raphael; Nogoceke, Everson; Bonifacio, Ezio; Sturm, Dorothee; Meyer-Puttlitz, Birgit; Boggi, Ugo; Saeger, Hans-Detlev; Filipponi, Franco; Lesche, Mathias; Meda, Paolo; Dahl, Andreas; Wigger, Leonore; Xenarios, Ioannis; Falchi, Mario; Thorens, Bernard; Weitz, Juergen; Bokvist, Krister; Lenzen, Sigurd; Rutter, Guy A.; Froguel, Philippe; von Buelow, Manon; Ibberson, Mark; Marchetti, Piero

The liver receptor homolog-1 (LRH-1) is expressed in human islets and protects β-cells against stress-induced apoptosis (vol 20, pg 2823, 2011)

肝脏受体同源物-1 (LRH-1) 在人胰岛中表达，并保护 β 细胞免受应激诱导的细胞凋亡 (第20卷，2823页，2011页)

HUMAN MOLECULAR GENETICS

IF3.2

2017-11-274

OAAI

Epigallocatechin-3-gallate (EGCG) activates AMPK through the inhibition of glutamate dehydrogenase in muscle and pancreatic β-cells: A potential beneficial effect in the pre-diabetic state?

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

IF2.8

2017-07-0159

OAAI

Claes B. Wollheim

个人简介

教育背景

工作经历

荣誉奖项

研究方向