Antony B. Holmes - Publications, H-index & Citations

Antony B. Holmes

Columbia University

26H指数

65论文数

6.5K被引数

收录论文 26

发表时间

Differential role of CREBBP missense and truncating mutations in germinal center development and lymphomagenesis CREBBP错义和截断突变在生发中心发育和淋巴瘤发生中的不同作用

Blood

IF23.1

2026-02-28

PREAI

Chuanjiang Yu; Mara Holloman; Andrew Kim; Yunchao Chang; Stefanie Meyer; Antony B. Holmes; Bowen Cai; Tongwei Mo; Katia Basso; Kostiantyn Dreval; Ryan D. Morin; Govind Bhagat; Charles G. Mullighan; Riccardo Dalla-Favera; Laura Pasqualucci

Role of Glucocorticoid Receptor in Normal and Malignant Germinal Center B Cells 糖皮质激素受体在正常和恶性生发中心B细胞中的作用

BLOOD

IF23.1

2024-11-05

PREAI

Corinaldesi, Clarissa; Holmes, Antony; Bal, Elodie; Amini-Farsani, Zeinab; Bhagat, Govind; Pasqualucci, Laura; Basso, Katia; Dalla-Favera, Riccardo

Single-cell transcriptomics of pediatric Burkitt lymphoma reveals intra-tumor heterogeneity and markers of therapy resistance

LEUKEMIA

IF13.4

2024-10-18

OAAI

Corinaldesi, Clarissa; Holmes, Antony B.; Martire, Gaia; Tosato, Anna; Rizzato, Domenico; Lovisa, Federica; Gallingani, Ilaria; Shen, Qiong; Ferrone, Lavinia; Harris, Marian; Davies, Kimberly; Molinaro, Luca; Mortara, Umberto; Dei Tos, Angelo Paolo; Ofori, Kenneth; D'Amore, Emanuele S. G.; Chiarle, Roberto; Ngan, Bo; Carraro, Elisa; Pillon, Marta; Hussein, Shafinaz; Bhagat, Govind; Pizzi, Marco; Mussolin, Lara; Basso, Katia

MEF2B C-terminal mutations enhance transcriptional activity and stability to drive B cell lymphomagenesis

NATURE COMMUNICATIONS

IF15.7

2024-08-21

OAAI

Yu, Chuanjiang; Shen, Qiong; Holmes, Antony B.; Mo, Tongwei; Tosato, Anna; Soni, Rajesh Kumar; Corinaldesi, Clarissa; Koul, Sanjay; Pasqualucci, Laura; Hussein, Shafinaz; Forouhar, Farhad; Dalla-Favera, Riccardo; Basso, Katia

ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustion

NATURE COMMUNICATIONS

IF15.7

2023-06-19

OAAI

Menolfi, Demis; Lee, Brian J.; Zhang, Hanwen; Jiang, Wenxia; Bowen, Nicole E.; Wang, Yunyue; Zhao, Junfei; Holmes, Antony; Gershik, Steven; Rabadan, Raul; Kim, Baek; Zha, Shan

KMT2D acetylation by CREBBP reveals a cooperative functional interaction at enhancers in normal and malignant germinal center B cells

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-03-09

OAAI

Vlasevska, Sofija; Garcia-Ibanez, Laura; Duval, Romain; Holmes, Antony B.; Jahan, Rahat; Cai, Bowen; Kim, Andrew; Mo, Tongwei; Basso, Katia; Soni, Rajesh K.; Bhagat, Govind; Dalla-Favera, Riccardo; Pasqualucci, Laura

Tracking Immunoglobulin Repertoire and Transcriptomic Changes in Germinal Center B Cells by Single-Cell Analysis 通过单细胞分析追踪生发中心b细胞的免疫球蛋白库和转录组学变化

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-01-12

OAAI

Corinaldesi, Clarissa; Holmes, Antony B.; Shen, Qiong; Grunstein, Eli; Pasqualucci, Laura; Dalla-Favera, Riccardo; Basso, Katia

Mutations in the transcription factor FOXO1 mimic positive selection signals to promote germinal center B cell expansion and lymphomagenesis

IMMUNITY

IF26.3

2021-08-01

OAAI

Roberto, Mark P.; Varano, Gabriele; Vinas-Castells, Rosa; Holmes, Antony B.; Kumar, Rahul; Pasqualucci, Laura; Farinha, Pedro; Scott, David W.; Dominguez-Sola, David

Single-cell analysis of germinal-center B cells informs on lymphoma cell of origin and outcome

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2020-06-30

128

OAAI

Holmes, Antony B.; Corinaldesi, Clarissa; Shen, Qiong; Kumar, Rahul; Compagno, Nicolo; Wang, Zhong; Nitzan, Mor; Grunstein, Eli; Pasqualucci, Laura; Dalla-Favera, Riccardo; Basso, Katia

miR-939 acts as tumor suppressor by modulating JUNB transcriptional activity in pediatric anaplastic large cell lymphoma

HAEMATOLOGICA

IF7.9

2020-04-16

OAAI

Garbin, Anna; Lovisa, Federica; Holmes, Antony B.; Damanti, Carlotta C.; Gallingani, Ilaria; Carraro, Elisa; Accordi, Benedetta; Veltri, Giulia; Pizzi, Marco; d'Amore, Emanuele S. G.; Pillon, Marta; Biffi, Alessandra; Basso, Katia; Mussolin, Lara

Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma

IMMUNITY

IF26.3

2019-09-01

OAAI

Meyer, Stefanie N.; Scuoppo, Claudio; Vlasevska, Sofija; Bal, Elodie; Holmes, Antony B.; Holloman, Mara; Garcia-Ibanez, Laura; Nataraj, Sarah; Duval, Romain; Vantrimpont, Thomas; Basso, Katia; Brooks, Nigel; Dalla-Favera, Riccardo; Pasqualucci, Laura

Organ-specific epigenetic reprogramming of leukemia cells: Clues to chemoresistance

CANCER RESEARCH

IF16.6

2017-07-01

PREAI

Cunningham, Isabel; Hamele-Bena, Diane; Papp, Audrey; Guo, Yan; Holmes, Antony B.; Shyr, Yu; Fisher, Rory A.

Common nonmutational NOTCH1 activation in chronic lymphocytic leukemia 慢性淋巴细胞白血病中常见的非突变NOTCH1活化

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-03-17

107

OAAI

Fabbri, Giulia; Holmes, Antony B.; Viganotti, Mara; Scuoppo, Claudio; Belver, Laura; Herranz, Daniel; Yan, Xiao-Jie; Kieso, Yasmine; Rossi, Davide; Gaidano, Gianluca; Chiorazzi, Nicholas; Ferrando, Adolfo A.; Dalla-Favera, Riccardo

The CREBBP Acetyltransferase Is a Haploinsufficient Tumor Suppressor in B-cell Lymphoma

CANCER DISCOVERY

IF33.3

2017-03-05

178

OAAI

Zhang, Jiyuan; Vlasevska, Sofija; Wells, Victoria A.; Nataraj, Sarah; Holmes, Antony B.; Duval, Romain; Meyer, Stefanie N.; Mo, Tongwei; Basso, Katia; Brindle, Paul K.; Hussein, Shafinaz; Dalla-Favera, Riccardo; Pasqualucci, Laura

The FOXO1 Transcription Factor Instructs the Germinal Center Dark Zone Program

IMMUNITY

IF26.3

2015-12-01

218

OAAI

Dominguez-Sola, David; Kung, Jennifer; Holmes, Antony B.; Wells, Victoria A.; Mo, Tongwei; Basso, Katia; Dalla-Favera, Riccardo

Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis

NATURE MEDICINE

IF50

2015-09-14

368

OAAI

Zhang, Jiyuan; Dominguez-Sola, David; Hussein, Shafinaz; Lee, Ji-Eun; Holmes, Antony B.; Bansal, Mukesh; Vlasevska, Sofija; Mo, Tongwei; Tang, Hongyan; Basso, Katia; Ge, Kai; Dalla-Favera, Riccardo; Pasqualucci, Laura

Genomic and proteomic characterization of two novel siphovirus infecting the sedentary facultative epibiont cyanobacterium Acaryochloris marina

ENVIRONMENTAL MICROBIOLOGY

IF4

2015-02-11

OAAI

Chan, Yi-Wah; Millard, Andrew D.; Wheatley, Peter J.; Holmes, Antony B.; Mohr, Remus; Whitworth, Anna L.; Mann, Nicholas H.; Larkum, Anthony W. D.; Hess, Wolfgang R.; Scanlan, David J.; Clokie, Martha R. J.

microRNA 28 controls cell proliferation and is down-regulated in B-cell lymphomas

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2014-05-19

OAAI

Schneider, Christof; Setty, Manu; Holmes, Antony B.; Maute, Roy L.; Leslie, Christina S.; Mussolin, Lara; Rosolen, Angelo; Dalla-Favera, Riccardo; Basso, Katia

An aberrant microRNA signature in childhood T-cell lymphoblastic lymphoma affecting CDKN1B expression, NOTCH1 and growth factor signaling pathways

LEUKEMIA

IF13.4

2014-04-14

OAAI

Mussolin, L.; Holmes, A. B.; Romualdi, C.; Sales, G.; D'Amore, E. S. G.; Ghisi, M.; Pillon, M.; Rosolen, A.; Basso, K.

Genetics of Follicular Lymphoma Transformation

CELL REPORTS

IF6.9

2014-01-01

472

OAAI

Pasqualucci, Laura; Khiabanian, Hossein; Fangazio, Marco; Vasishtha, Mansi; Messina, Monica; Holmes, Antony B.; Ouillette, Peter; Trifonov, Vladimir; Rossi, Davide; Tabbo, Fabrizio; Ponzoni, Maurilio; Chadburn, Amy; Murty, Vundavalli V.; Bhagat, Govind; Gaidano, Gianluca; Inghirami, Giorgio; Malek, Sami N.; Rabadan, Raul; Dalla-Favera, Riccardo

研究方向