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G

Geert-Jan van Gemert

Radboud University Medical Center
H指数:50
被引数:7,717

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Pfs230 domain 12 is a potent malaria transmission–blocking vaccine candidate

Pfs230 domain 12是一种有效的疟疾传播阻断疫苗候选物。

Science Advances
IF12.5
2025-11-070
PRE
Maartje R. Inklaar; Roos M. de Jong; Dari F. Da; Lisanne L. Hubregtse; Maartje Meijer; Karina Teelen; Ezra T. Bekkering; Sanne Grievink; Marga van de Vegte-Bolmer; Geert-Jan van Gemert; Rianne Stoter; Hikaru Nagaoka; Takafumi Tsuboi; Eizo Takashima; Cornelia G. Spruijt; Michiel Vermeulen; Roch K. Dabire; Emmanuel Arinaitwe; Anna Cohuet; Teun Bousema; Matthijs M. Jore
Structural elucidation of full-length Pfs48/45 in complex with potent monoclonal antibodies isolated from a naturally exposed individual

全长Pfs48/45与从自然暴露个体中分离的强效单克隆抗体复合物的结构阐明

NATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
2025-05-220
OA
Kucharska, Iga; Ivanochko, Danton; Hailemariam, Sophia; Inklaar, Maartje R.; Kim, Hee Ryung; Teelen, Karina; Stoter, Rianne; van de Vegte-bolmer, Marga; van Gemert, Geert-Jan; Semesi, Anthony; Mcleod, Brandon; Ki, Ahyoung; Lee, Won-Kyu; Rubinstein, John L.; Jore, Matthijs M.
A modular mRNA vaccine platform encoding antigen-presenting capsid virus-like particles enhances the immunogenicity of the malaria antigen Pfs25

一种编码抗原呈递的衣壳样病毒样颗粒的模块化mRNA疫苗平台增强了疟疾抗原Pfs25的免疫原性

NATURE NANOTECHNOLOGY
IF34.9
2025-05-140
PRE
Fougeroux, Cyrielle; Hagen, Sven Hendrik; Goksoyr, Louise; Aves, Kara-Lee; Okholm, Anna Kathrine; Morin, Candice; Lokras, Abhijeet Girish; Baghel, Saahil Sandeep; Foged, Camilla; van de Vegte-bolmer, Marga; van Gemert, Geert-Jan; Jore, Matthijs M.; Vidal-Calvo, Elena Ethel; Gustavsson, Tobias; Salanti, Ali; Theander, Thor Grundtvig; Nielsen, Morten Agertoug; de Jongh, Willem Adriaan; Bertelsen, Adam Frederik Sander
Potent transmission-blocking monoclonal antibodies from naturally exposed individuals target a conserved epitope on Plasmodium falciparum Pfs230
IMMUNITY
IF26.3
2023-02-0110
OAAI
Ivanochko, Danton; Fabra-Garcia, Amanda; Teelen, Karina; van de Vegete-Bolmer, Marga; van Gemert, Geert-Jan; Newton, Jocelyn; Semesi, Anthony; de Bruijni, Marloes; Bolscher, Judith; Ramjith, Jordache; Szabat, Marta; Vogt, Stefanie; Kraft, Lucas; Duncan, Sherie; Lee, Shwu-Maan; Kamya, Moses R.; Feeney, Margaret E.; Jagannathan, Prasanna; Greenhouse, Bryan; Sauerwein, Robert W.; King, C. Richter; MacGill, Randall S.; Bousem, Teun; Jore, Matthijs M.; Julien, Jean -Philippe
Highly potent, naturally acquired human monoclonal antibodies against Pfs48/45 block Plasmodium falciparum transmission to mosquitoes
IMMUNITY
IF26.3
2023-02-0111
OAAI
Fabra-Garcia, Amanda; Hailemariam, Sophia; de Jong, Roos M.; Janssen, Kirsten; Teelen, Karina; van de Vegte-Bolmer, Marga; van Gemert, Geert-Jan; Ivanochko, Danton; Semesi, Anthony; McLeod, Brandon; Vos, Martijn W.; de Bruijni, Marloes H. C.; Bolscher, Judith M.; Szabat, Marta; Vogt, Stefanie; Kraft, Lucas; Duncan, Sherie; Kamya, Moses R.; Feeney, Margaret E.; Jagannathan, Prasanna; Greenhouse, Bryan; Dechering, Koen J.; Sauerwein, Robert W.; King, C. Richter; MacGill, Randall S.; Bousema, Teun; Julien, Jean-Philippe; Jore, Matthijs M.
Safety, tolerability, and Plasmodium falciparum transmissionreducing activity of monoclonal antibody TB31F: a singlecentre, open-label, first-in-human, dose-escalation, phase 1 trial in healthy malaria-naive adults
LANCET INFECTIOUS DISEASES
IF31
2022-11-0121
OAAI
van der Boor, Saskia C.; Smit, Merel J.; van Beek, Stijn W.; Ramjith, Jordache; Teelen, Karina; van de Vegte-Bolmer, Marga; Van Gemert, Geert-Jan; Pickkers, Peter; Wu, Yimin; Locke, Emily; Lee, Shwu-Maan; Aponte, John; King, C. Richter; Birkett, Ashley J.; Miura, Kazutoyo; Ayorinde, Morolayo A.; Sauerwein, Robert W.; ter Heine, Rob; Ockenhouse, Christian F.; Bousema, Teun; Jore, Matthijs M.; McCall, Matthew B. B.
Vaccination with a structure-based stabilized version of malarial antigen Pfs48/45 elicits ultra-potent transmission-blocking antibody responses
IMMUNITY
IF26.3
2022-09-0131
OAAI
McLeod, Brandon; Mabrouk, Moustafa T.; Miura, Kazutoyo; Ravichandran, Rashmi; Kephart, Sally; Hailemariam, Sophia; Pham, Thao P.; Semesi, Anthony; Kucharska, Iga; Kundu, Prasun; Huang, Wei-Chiao; Johnson, Max; Blackstone, Alyssa; Pettie, Deleah; Murphy, Michael; Kraft, John C.; Leaf, Elizabeth M.; Jiao, Yang; Van de Vegte-Bolmer, Marga; Van Gemert, Geert-Jan; Ramjith, Jordache; King, C. Richter; MacGill, Randall S.; Wu, Yimin; Lee, Kelly K.; Jore, Matthijs M.; King, Neil P.; Lovell, Jonathan F.; Julien, Jean-Philippe
Artemisinin-independent inhibitory activity of Artemisia sp. infusions against different Plasmodium stages including relapse-causing hypnozoites
LIFE SCIENCE ALLIANCE
IF2.9
2021-12-0215
OAAI
Ashraf, Kutub; Tajeri, Shahin; Arnold, Christophe-Sebastien; Amanzougaghene, Nadia; Franetich, Jean-Francois; Vantaux, Amelie; Soulard, Valerie; Bordessoulles, Mallaury; Cazals, Guillaume; Bousema, Teun; Van Gemert, Geert-Jan; Le Grand, Roger; Dereuddre-Bosquet, Nathalie; Barale, Jean-Christophe; Witkowski, Benoit; Snounou, Georges; Duval, Romain; Botte, Cyrille Y.; Mazier, Dominique

研究方向

暂未获取到该数据
R
Robert W. Sauerwein
H 指数:101论文数:509被引数:3.3万
M
Marga van de Vegte‐Bolmer
H 指数:37论文数:99被引数:4,857
T
Teun Bousema
H 指数:85论文数:543被引数:2.3万
W
Wouter Graumans
H 指数:28论文数:94被引数:2,672
K
Karina Teelen
H 指数:33论文数:104被引数:3,566
M
Matthijs M. Jore
H 指数:28论文数:86被引数:7,899
C
Cornelus C. Hermsen
H 指数:43论文数:119被引数:6,250
R
Rianne Siebelink‐Stoter
H 指数:15论文数:36被引数:1,173
K
Kjerstin Lanke
H 指数:45论文数:146被引数:6,019
M
Martijn Vos
H 指数:22论文数:56被引数:1,879