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K

Ken R. Bracke

ghent university hospital
H指数:54
被引数:9,633

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Cigarette smoke drives polystyrene nanoparticles-associated airway epithelial damage and chronic obstructive pulmonary disease-like features

香烟烟雾驱动聚苯乙烯纳米颗粒相关的气道上皮损伤和慢性阻塞性肺疾病样特征

Scientific Reports
IF3.9
2026-07-280
OA
Davida Mirra; Francesca Panico; Yiannis De Meersman; Giuseppe Spaziano; Simona Altieri; Eleonora Caiazzo; Ken R. Bracke; Pasquale Iovino; Raffaele Marfella; Carmine Lubritto; Giuseppe Paolisso; Tania Maes; Bruno D’Agostino
Selective Replacement of Cholesterol with Cationic Amphiphilic Drugs Enables the Design of Lipid Nanoparticles with Improved RNA Delivery

用阳离子两亲性药物选择性替代胆固醇使得能够设计具有改善的RNA递送的脂质纳米颗粒

NANO LETTERS
IF9.1
2024-03-045
OA
Bogaert, Bram; Debisschop, Aliona; Ehouarne, Thomas; Van Eeckhoutte, Hannelore P.; De Volder, Joyceline; Jacobs, An; Pottie, Eline; De Rycke, Riet; Crabbe, Aurelie; Mestdagh, Pieter; Lentacker, Ine; Brusselle, Guy G.; Stove, Christophe; Verstraelen, Sandra; Maes, Tania; Bracke, Ken R.; De Smedt, Stefaan C.; Raemdonck, Koen
TLR7 promotes smoke-induced experimental lung damage through the activity of mast cell tryptase

TLR7通过肥大细胞类胰蛋白酶活性促进烟雾诱导的实验性肺损伤

NATURE COMMUNICATIONS
IF15.7
2023-11-145
OAAI
Liu, Gang; Haw, Tatt Jhong; Starkey, Malcolm R.; Philp, Ashleigh M.; Pavlidis, Stelios; Nalkurthi, Christina; Nair, Prema M.; Gomez, Henry M.; Hanish, Irwan; Hsu, Alan CY.; Hortle, Elinor; Pickles, Sophie; Rojas-Quintero, Joselyn; Estepar, Raul San Jose; Marshall, Jacqueline E.; Kim, Richard Y.; Collison, Adam M.; Mattes, Joerg; Idrees, Sobia; Faiz, Alen; Hansbro, Nicole G.; Fukui, Ryutaro; Murakami, Yusuke; Cheng, Hong Sheng; Tan, Nguan Soon; Chotirmall, Sanjay H.; Horvat, Jay C.; Foster, Paul S.; Oliver, Brian GG.; Polverino, Francesca; Ieni, Antonio; Monaco, Francesco; Caramori, Gaetano; Sohal, Sukhwinder S.; Bracke, Ken R.; Wark, Peter A.; Adcock, Ian M.; Miyake, Kensuke; Sin, Don D.; Hansbro, Philip M.
RIPK1 kinase-dependent inflammation and cell death contribute to the pathogenesis of COPD

RIPK1激酶依赖性炎症和细胞死亡在COPD发病机制中的作用

EUROPEAN RESPIRATORY JOURNAL
IF21
2022-12-2225
OA
Van Eeckhoutte, Hannelore P.; Donovan, Chantal; Kim, Richard Y.; Conlon, Thomas M.; Ansari, Meshal; Khan, Haroon; Jayaraman, Ranjith; Hansbro, Nicole G.; Dondelinger, Yves; Delanghe, Tom; Beal, Allison M.; Geddes, Brad; Bertin, John; Vanden Berghe, Tom; De Volder, Joyceline; Maes, Tania; Vandenabeele, Peter; Vanaudenaerde, Bart M.; Deforce, Dieter; Skevin, Sonja; Van Nieuwerburgh, Filip; Verhamme, Fien M.; Joos, Guy F.; Idrees, Sobia; Schiller, Herbert B.; Yildirim, Ali Oender; Faiz, Alen; Bertrand', Mathieu J. M.; Brusselle, Guy G.; Hansbro, Philip M.; Bracke, Ken R.
Adverse roles of mast cell chymase-1 in COPD
EUROPEAN RESPIRATORY JOURNAL
IF21
2022-12-0820
OA
Liu, Gang; Jarnicki, Andrew G.; Paudel, Keshav R.; Lu, Wenying; Wadhwa, Ridhima; Philp, Ashleigh M.; Van Eeckhoutte, Hannelore; Marshall, Jacqueline E.; Malyla, Vamshikrishna; Katsifis, Angelica; Fricker, Michael; Hansbro, Nicole G.; Dua, Kamal; Kermani, Nazanin Z.; Eapen, Mathew S.; Tiotiu, Angelica; Chung, K. Fan; Caramori, Gaetano; Bracke, Ken; Adcock, Ian M.; Sohal, Sukhwinder S.; Wark, Peter A.; Oliver, Brian G.; Hansbro, Philip M.
Organ-specific genome diversity of replication-competent SARS-CoV-2 (vol 12, 6612, 2021)
NATURE COMMUNICATIONS
IF15.7
2022-10-212
OAAI
Van Cleemput, Jolien; van Snippenberg, Willem; Lambrechts, Laurens; Dendooven, Amelie; D'Onofrio, Valentino; Couck, Liesbeth; Trypsteen, Wim; Vanrusselt, Jan; Theuns, Sebastiaan; Vereecke, Nick; van den Bosch, Thierry P. P.; Lammens, Martin; Driessen, Ann; Achten, Ruth; Bracke, Ken R.; van den Broeck, Wim; von der Thusen, Jan; Nauwynck, Hans; Van Dorpe, Jo; Gerlo, Sarah; Maes, Piet; Cox, Janneke; Vandekerckhove, Linos
The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPD
NATURE COMMUNICATIONS
IF15.7
2022-03-1453
OAAI
Guensel, Gizem Guenes; Conlon, Thomas M.; Jeridi, Aicha; Kim, Rinho; Ertuez, Zeynep; Lang, Niklas J.; Ansari, Meshal; Novikova, Mariia; Jiang, Dongsheng; Strunz, Maximilian; Gaianova, Mariia; Hollauer, Christine; Gabriel, Christina; Angelidis, Ilias; Doll, Sebastian; Pestoni, Jeanine C.; Edelmann, Stephanie L.; Kohlhepp, Marlene Sophia; Guillot, Adrien; Bassler, Kevin; Van Eeckhoutte, Hannelore P.; Kayalar, Oezgecan; Konyalilar, Nur; Kanashova, Tamara; Rodius, Sophie; Ballester-Lopez, Carolina; Robles, Carlos M. Genes; Smirnova, Natalia; Rehberg, Markus; Agarwal, Charu; Krikki, Ioanna; Piavaux, Benoit; Verleden, Stijn E.; Vanaudenaerde, Bart; Koenigshoff, Melanie; Dittmar, Gunnar; Bracke, Ken R.; Schultze, Joachim L.; Watz, Henrik; Eickelberg, Oliver; Stoeger, Tobias; Burgstaller, Gerald; Tacke, Frank; Heissmeyer, Vigo; Rinkevich, Yuval; Bayram, Hasan; Schiller, Herbert B.; Conrad, Marcus; Schneider, Robert; Yildirim, Ali Oender
microRNA-21-mediated SATB1/S100A9/NF-κB axis promotes chronic obstructive pulmonary disease pathogenesis

microRNA-21-mediated SATB1/S100A9/nf-κb轴在慢性阻塞性肺疾病发病中的作用

SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2021-11-2464
PRE
Kim, Richard Y.; Sunkara, Krishna P.; Bracke, Ken R.; Jarnicki, Andrew G.; Donovan, Chantal; Hsu, Alan C.; Ieni, Antonio; Beckett, Emma L.; Galvao, Izabela; Wijnant, Sara; Ricciardolo, Fabio Lm; Di Stefano, Antonino; Haw, Tatt Jhong; Liu, Gang; Ferguson, Angela L.; Palendira, Umamainthan; Wark, Peter A.; Conickx, Griet; Mestdagh, Pieter; Brusselle, Guy G.; Caramori, Gaetano; Foster, Paul S.; Horvat, Jay C.; Hansbro, Philip M.
Organ-specific genome diversity of replication-competent SARS-CoV-2

具有复制能力的SARS-CoV-2的器官特异性基因组多样性

NATURE COMMUNICATIONS
IF15.7
2021-11-1649
OAAI
Van Cleemput, Jolien; van Snippenberg, Willem; Lambrechts, Laurens; Dendooven, Amelie; D'Onofrio, Valentino; Couck, Liesbeth; Trypsteen, Wim; Vanrusselt, Jan; Theuns, Sebastiaan; Vereecke, Nick; van den Bosch, Thierry P. P.; Lammens, Martin; Driessen, Ann; Achten, Ruth; Bracke, Ken R.; Van den Broeck, Wim; Von der Thusen, Jan; Nauwynck, Hans; Van Dorpe, Jo; Gerlo, Sarah; Maes, Piet; Cox, Janneke; Vandekerckhove, Linos
Necroptosis Signaling Promotes Inflammation, Airway Remodeling, and Emphysema in Chronic Obstructive Pulmonary Disease

坏死性凋亡信号促进慢性阻塞性肺疾病的炎症，气道重塑和肺气肿

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
IF19.4
2021-09-15123
OA
Lu, Zhe; Van Eeckhoutte, Hannelore P.; Liu, Gang; Nair, Prema M.; Jones, Bernadette; Gillis, Caitlin M.; Nalkurthi, B. Christina; Verhamme, Fien; Buyle-Huybrecht, Tamariche; Vandenabeele, Peter; Vanden Berghe, Tom; Brusselle, Guy G.; Horvat, Jay C.; Murphy, James M.; Wark, Peter A.; Bracke, Ken R.; Fricker, Michael; Hansbro, Philip M.

研究方向

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