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R

Robert L. Bowman

Memorial Sloan Kettering Cancer Center
H指数:51
被引数:1.5万

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Prognostic and therapeutic implications of BRAF mutations in acute myeloid leukemia

BRAF突变在急性髓系白血病中的预后和治疗意义

Leukemia
IF13.4
2026-06-150
OAAI
Darren Lee; Yazan Abu-Shihab; Kate Plas; Deedra Nicolet; Krzysztof Mrózek; Mark J. Routbort; Keyur P. Patel; Christopher J. Walker; Jill Buss; Andrew R. Stiff; Andrea Laganson; Courtney D. DiNardo; Naval G. Daver; Tapan M. Kadia; Farhad Ravandi; Andrew J. Carroll; Jonathan E. Kolitz; Bayard L. Powell; William G. Blum; Maria R. Baer; Guido Marcucci; Geoffrey L. Uy; Wendy Stock; Richard M. Stone; L. Jeffrey Medeiros; John C. Byrd; James S. Blachly; Robert L. Bowman; Jeffrey W. Tyner; Sanam Loghavi; Ann-Kathrin Eisfeld; Linde A. Miles
Chemoresistance of TP53 mutant acute myeloid leukemia requires the mevalonate byproduct, geranylgeranyl pyrophosphate, for induction of an adaptive stress response

TP53突变型急性髓系白血病的化疗耐药性需要甲羟戊酸代谢产物法尼基焦磷酸，以诱导适应性应激反应。

Leukemia
IF13.4
2025-07-090
OAAI
Sarah J. Skuli; A’ishah Bakayoko; Marisa Kruidenier; Bryan Manning; Paige Pammer; Akmal Salimov; Owen Riley; Gisela Brake-Sillá; Derrick Dopkin; Michael Bowman; Leslie N. Martinez-Gutierrez; Colin C. Anderson; Julie A. Reisz; Roberta Buono; Madhuri Paul; Estelle Saland; Francesca Liccardo; Ann DeVine; Sarah Wong; Jimmy P. Xu; Eva Nee; Ryan Hausler; Steffen Boettcher; Said M. Sebti; Catherine Lai; Kara N. Maxwell; Jean-Emmanuel Sarry; David A. Fruman; Angelo D’Alessandro; Clementina Mesaros; Brian Keith; M. Celeste Simon; Pamela J. Sung; Gerald Wertheim; Nicolas Skuli; Robert L. Bowman; Andrew Matthews; Martin Carroll
Mutant IDH1 cooperates with NPM1c or FLT3ITD to drive distinct myeloid diseases and molecular outcomes

突变IDH1与NPM1c或FLT3ITD协同作用，驱动不同的髓系疾病和分子结局。

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2025-05-160
OA
Sakamoto, Takashi; Leca, Julie; Zhang, Xin; Meydan, Cem; Foox, Jonathan; Ramachandran, Parameswaran; Hendrikse, Liam D.; Zhou, Wenjing; Berger, Thorsten; Fortin, Jerome; Chan, Steven M.; Chiang, Ming-Feng; Inoue, Satoshi; Li, Wanda Y.; Chu, Mandy F.; Duncan, Gordon S.; Wakeham, Andrew; Lemonnier, Francois; Tobin, Chantal; Mcwilliam, Ryan; Colonna, Isabelle; Bontoux, Christophe; Jafari, Soode Moghadas; Bowman, Robert L.; Nicolay, Brandon; Ronseaux, Sebastien; Narayanaswamy, Rohini; Levine, Ross L.; Melnick, Ari M.; Mason, Christopher E.; Minden, Mark D.
Combined Human and In Vivo Analyses Implicate the Critical Importance of Acute Myeloid Leukemia Associated CD8 T Cells and Identifies Their Molecular Dysfunction

结合人类和活体分析表明急性髓系白血病相关CD8 T细胞具有关键重要性，并确定了其分子功能障碍

BLOOD
IF23.1
2024-11-050
PRE
Chu, Y. Emily; Cottam, Matthew A.; Potts, Chad R.; Dickerson, Kirsten M.; Jenkins, Matthew; Cartailler, Justin A.; Lu, Rui; Lee, Stanley C.; Levine, Ross L.; Bowman, Robert L.; Welner, Robert; Ferrell, P. Brent
Cellular taxonomy of the preleukemic bone marrow niche of acute myeloid leukemia
LEUKEMIA
IF13.4
2024-10-020
OAAI
Goda, Chinmayee; Kulkarni, Rohan; Bustos, Yaphet; Li, Wenjun; Rudich, Alexander; Balcioglu, Ozlen; Chidester, Sadie; Urs, Amog P.; Karunasiri, Malith; Al-Marrawi, Yzen; Korn, Erin; Kanna, Sanjay; Garfinkle, Elizabeth A. R.; Shah, Nisarg; Wooten, Ashley; Mundy-Bosse, Bethany; Sehgal, Lalit; Zhang, Bin; Marcucci, Guido; Mardis, Elaine R.; Garzon, Ramiro; Bowman, Robert L.; Viny, Aaron D.; Miles, Linde A.; Miller, Katherine E.; Dorrance, Adrienne M.
CRISPR Dependency Screens in Primary Hematopoietic Stem Cells Identify KDM3B as a Genotype-specific Vulnerability in IDH2- and TET2-mutant Cells
CANCER DISCOVERY
IF33.3
2024-05-301
PRE
Waarts, Michael R.; Mowla, Shoron; Boileau, Meaghan; Benitez, Anthony R. Martinez; Sango, Junya; Bagish, Maya; Fernandez-Maestre, Ines; Shan, Yufan; Eisman, Shira E.; Park, Young C.; Wereski, Matthew; Csete, Isabelle; O'Connor, Kavi; Romero-Vega, Angelica C.; Miles, Linde A.; Xiao, Wenbin; Wu, Xiaodi; Koche, Richard P.; Armstrong, Scott A.; Shih, Alan H.; Papapetrou, Eirini P.; Butler, Jason M.; Cai, Sheng F.; Bowman, Robert L.; Levine, Ross L.
Mutation order in acute myeloid leukemia identifies uncommon patterns of evolution and illuminates phenotypic heterogeneity

急性髓性白血病的突变顺序可确定罕见的进化模式并阐明表型异质性

LEUKEMIA
IF13.4
2024-03-111
OA
Schwede, Matthew; Jahn, Katharina; Kuipers, Jack; Miles, Linde A.; Bowman, Robert L.; Robinson, Troy; Furudate, Ken; Uryu, Hidetaka; Tanaka, Tomoyuki; Sasaki, Yuya; Ediriwickrema, Asiri; Benard, Brooks; Gentles, Andrew J.; Levine, Ross; Beerenwinkel, Niko; Takahashi, Koichi; Majeti, Ravindra
Jak2V617F Reversible Activation Shows Its Essential Requirement in Myeloproliferative Neoplasms

Jak2V617F可逆激活显示其在骨髓增殖性肿瘤中的基本要求

CANCER DISCOVERY
IF33.3
2024-01-1210
OAAI
Dunbar, Andrew J.; Bowman, Robert L.; Park, Young C.; O'Connor, Kavi; Izzo, Franco; Myers, Robert M.; Karzai, Abdul; Zaroogian, Zachary; Kim, Won Jun; Fernandez-Maestre, Ines; Waarts, Michael R.; Nazir, Abbas; Xiao, Wenbin; Codilupi, Tamara; Brodsky, Max; Farina, Mirko; Cai, Louise; Cai, Sheng F.; Wang, Benjamin; An, Wenbin; Yang, Julie L.; Mowla, Shoron; Eisman, Shira E.; Somasundara, Amritha Varshini Hanasoge; Glass, Jacob L.; Mishra, Tanmay; Houston, Remie; Guzzardi, Emily; Benitez, Anthony R. Martinez; Viny, Aaron D.; Koche, Richard P.; Meyer, Sara C.; Landau, Dan A.; Levine, Ross L.
FLT3 tyrosine kinase inhibition modulates PRC2 and promotes differentiation in acute myeloid leukemia

FLT3酪氨酸激酶抑制调节PRC2并促进急性髓系白血病的分化

LEUKEMIA
IF13.4
2024-01-057
OA
Sung, Pamela J.; Selvam, Murugan; Riedel, Simone S.; Xie, Hongbo M.; Bryant, Katie; Manning, Bryan; Wertheim, Gerald B.; Kulej, Katarzyna; Pham, Lucie; Bowman, Robert L.; Peresie, Jennifer; Nemeth, Michael J.; Levine, Ross L.; Garcia, Benjamin A.; Meyer, Sara E.; Sidoli, Simone; Bernt, Kathrin M.; Carroll, Martin
Single-cell genotypic and phenotypic analysis of measurable residual disease in acute myeloid leukemia

急性髓系白血病可测量残留病的单细胞基因型和表型分析

SCIENCE ADVANCES
IF12.5
2023-09-2212
OAAI
Robinson, Troy M.; Bowman, Robert L.; Persaud, Sonali; Liu, Ying; Neigenfind, Rosemary; Gao, Qi; Zhang, Jingping; Sun, Xiaotian; Miles, Linde A.; Cai, Sheng F.; Sciambi, Adam; Llanso, Aaron; Famulare, Christopher; Goldberg, Aaron; Dogan, Ahmet; Roshal, Mikhail; Levine, Ross L.; Xiao, Wenbin
Hematopoietic-specific heterozygous loss of Dnmt3a exacerbates colitis-associated colon cancer
JOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
2023-08-244
OAAI
Feng, Yang; Yuan, Qingchen; Newsome, Rachel C.; Robinson, Troy; Bowman, Robert L.; Zuniga, Ashley N.; Hall, Kendra N.; Bernsten, Cassandra M.; Shabashvili, Daniil E.; Krajcik, Kathryn I.; Gunaratne, Chamara; Zaroogian, Zachary J.; Venugopal, Kartika; Casellas Roman, Heidi L.; Levine, Ross L.; Chatila, Walid K.; Yaeger, Rona; Riva, Alberto; Jobin, Christian; Kopinke, Daniel; Avram, Dorina; Guryanova, Olga A.
Molecular predictors of immunophenotypic measurable residual disease clearance in acute myeloid leukemia
AMERICAN JOURNAL OF HEMATOLOGY
IF9.9
2022-10-3115
OAAI
Stahl, Maximilian; Derkach, Andriy; Farnoud, Noushin; Bewersdorf, Jan Philipp; Robinson, Troy; Famulare, Christopher; Cho, Christina; Devlin, Sean; Menghrajani, Kamal; Patel, Minal A.; Cai, Sheng F.; Miles, Linde A.; Bowman, Robert L.; Geyer, Mark B.; Dunbar, Andrew; Epstein-Peterson, Zachary D.; McGovern, Erin; Schulman, Jessica; Glass, Jacob L.; Taylor, Justin; Viny, Aaron D.; Stein, Eytan M.; Getta, Bartlomiej; Arcila, Maria E.; Gao, Qi; Barker, Juliet; Shaffer, Brian C.; Papadopoulos, Esperanza B.; Gyurkocza, Boglarka; Perales, Miguel-Angel; Abdel-Wahab, Omar; Levine, Ross L.; Giralt, Sergio A.; Zhang, Yanming; Xiao, Wenbin; Pai, Nidhi; Papaemmanuil, Elli; Tallman, Martin S.; Roshal, Mikhail; Goldberg, Aaron D.

研究方向

暂未获取到该数据
R
Ross L. Levine
H 指数:147论文数:1,480被引数:9.3万
L
Linde A. Miles
H 指数:17论文数:96被引数:3,225
J
Johanna A. Joyce
H 指数:74论文数:210被引数:4.3万
W
Wenbin Xiao
H 指数:34论文数:211被引数:1.1万
A
Aaron D. Viny
H 指数:25论文数:209被引数:3,637
L
Lisa Sevenich
H 指数:20论文数:56被引数:5,292
S
Sheng F. Cai
H 指数:23论文数:163被引数:3,491
S
Sara E. Meyer
H 指数:12论文数:97被引数:1,005
F
Franck Rapaport
H 指数:41论文数:241被引数:9,379
F
Florian Klemm
H 指数:25论文数:48被引数:5,204