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K

Keqiang Ye

Emory University
H指数:80
被引数:2.3万

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A high-content screening combined with AI-assisted vibe coding approach identifies a mitochondria-to-lysosome signaling cascade ameliorating Parkinson’s pathology

高通量筛选与AI辅助的振动编码方法鉴定出一种改善帕金森病理的线粒体至溶酶体信号级联

Acta Pharmaceutica Sinica B
IF14.6
2026-10-010
OAAI
Xuxu Zhuang; Jingfang Luo; Ziying Wang; Olympia Apokotou; Xinjie Guan; Xiaoxia Peng; Yu Dong; Jiayue Chen; Liming Xie; Chen Ming; Hanming Shen; Evandro F. Fang; Min Li; Huanxing Su; Keqiang Ye; Chaoyang Liu; Rebecca Matsas; Florentia Papastefanaki; Jieqiong Tan; Jiahong Lu
DeepDrugDiscovery identifies blood–brain barrier permeable autophagy enhancers for Alzheimer’s disease

DeepDrugDiscovery鉴定出可透过血脑屏障的自噬增强剂，用于阿尔茨海默病治疗

Nature Biomedical Engineering
IF26.6
2026-04-240
PRE
Yu Dong; Xianglu Xiao; Xu-Xu Zhuang; Wenfan Wu; Zi-Ying Wang; Shuang Zhang; Jin-Tao Li; Ke Zhang; Wen-Yu Fu; Jun-Ming Chen; Shi Hang Xiong; Shenglong Deng; Krinos Li; Chao Ma; Wangzhen Jin; Xurui Jin; Qiwei Cai; Han-Ming Shen; Min Li; Huanxing Su; Jian-Bo Wan; Hua Yu; Defang Ouyang; Keqiang Ye; Evandro F. Fang; Chris Soon Heng Tan; Guang Yang; Zhangming Niu; Jia-Hong Lu
Targeting FSH for osteoporosis, obesity, and Alzheimer’s disease

靶向FSH治疗骨质疏松症、肥胖症和阿尔茨海默病

Trends in Molecular Medicine
IF13.8
2025-06-050
PRE
Funda Korkmaz; Judit Gimenez-Roig; Farhath Sultana; Victoria Laurencin; Fasilet Sen; Liam Cullen; Steven Sims; Anusha Pallapati; Satish Rojekar; Guzel Burganova; Georgii Pevnev; Uliana Cheliadinova; Darya Vasilyeva; Ofer Moldavski; Tal Frolinger; Anisa Gumerova; Orly Barak; Vitaly Ryu; Daria Lizneva; Keqiang Ye; Anne Schafer; Clifford J. Rosen; Tony Yuen; Se-Min Kim; Mone Zaidi
EBP1 potentiates amyloid β pathology by regulating γ-secretase

EBP1通过调节γ-分泌酶增强淀粉样β病理学

NATURE AGING
IF19.4
2025-01-080
PRE
Kim, Byeong-Seong; Hwang, Inwoo; Ko, Hyo Rim; Kim, Young Kwan; Kim, Hee Jin; Seo, Sang Won; Choi, Yujung; Lim, Sungsu; Kim, Yun Kyung; Nie, Shuke; Ye, Keqiang; Park, Jong-Chan; Lee, Yunjong; Lee, Seung Eun; Kim, Daesik; Cho, Sung-Woo; Ahn, Jee-Yin
Neuronal FAM171A2 mediates α-synuclein fibril uptake and drives Parkinson’s disease

神经元FAM171A2介导α-突触核蛋白纤维摄取并驱动帕金森病

Science
IF45.8
2025-01-010
PRE
Kaimin Wu; Qianhui Xu; Yiqi Liu; Yiwei Feng; Sida Han; Ya-Ru Zhang; Shi-Dong Chen; Yu Xing Guo; Bang‐Sheng Wu; Lingzhi Ma; Yi Zhang; Yilin Chen; Yang Liu; Zhaofei Yang; Yujie Xiao; Tingting Wang; Jue Zhao; Shu-Fen Chen; Mei Cui; Boxun Lu; Weidong Le; Yousheng Shu; Keqiang Ye; Jiayi Li; Wensheng Li; Jian Wang; Cong Liu; Peng Yuan; Jin‐Tai Yu
Gene-dose-dependent reduction of Fshr expression improves spatial memory deficits in Alzheimer's mice
MOLECULAR PSYCHIATRY
IF10.1
2024-11-150
PRE
Korkmaz, Funda; Sims, Steven; Sen, Fazilet; Sultana, Farhath; Laurencin, Victoria; Cullen, Liam; Pallapati, Anusha; Liu, Avi; Chen, Ronald; Rojekar, Satish; Pevnev, Georgii; Cheliadinova, Uliana; Vasilyeva, Darya; Burganova, Guzel; Macdonald, Anne; Saxena, Mansi; Goosens, Ki; Rosen, Clifford J.; Barak, Orly; Lizneva, Daria; Gumerova, Anisa; Ye, Keqiang; Ryu, Vitaly; Yuen, Tony; Frolinger, Tal; Zaidi, Mone

研究方向

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X
Xia Liu
H 指数:60论文数:273被引数:1.1万
S
Seong Su Kang
H 指数:36论文数:71被引数:4,048
Z
Zhentao Zhang
H 指数:51论文数:346被引数:8,766
E
Eun Hee Ahn
H 指数:29论文数:63被引数:2,320
Z
Zhi-Hao Wang
H 指数:31论文数:73被引数:2,648
Y
Yiyuan Xia
H 指数:30论文数:72被引数:3,346
S
Sung‐Wuk Jang
H 指数:26论文数:73被引数:3,146
H
Hongbo R. Luo
H 指数:59论文数:224被引数:1.1万
C
Chi Bun Chan
H 指数:29论文数:82被引数:2,524
齐
齐琦
H 指数:57论文数:553被引数:1.3万