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R

Raúl Mostoslavsky

broad institute
H指数:67
被引数:3.0万

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ZNF280A links DNA double-strand break repair to human 22q11.2 distal deletion syndrome

ZNF280A将DNA双链断裂修复与人类22 q11.2远端缺失综合征联系起来

Nature Cell Biology
IF19.1
2025-06-160
PRE
Thomas L. Clarke; Hyo Min Cho; Ilaria Ceppi; Boya Gao; Tribhuwan Yadav; Giorgia G. Silveira; Ruben Boon; Barbara Martinez-Pastor; Nana Yaa A. Amoh; Belen Machin; Tiziano Bernasocchi; Dua Ashfaq; Josefina Mendez; Zeeba Kamaliyan; José Del Río Pantoja; Giuliana Sardi Rogines; Blaine T. Crowley; Daniel E. McGinn; Victoria Giunta; Oanh Tran; Elaine H. Zackai; Li Lan; Lee Zou; Beverly S. Emanuel; Donna M. McDonald-McGinn; Petr Cejka; Raul Mostoslavsky
Derepressing nuclear pyruvate dehydrogenase induces therapeutic cancer cell reprogramming

去抑制核内丙酮酸脱氢酶可诱导治疗性癌细胞重编程

Cell Metabolism
IF30.9
2025-06-110
PRE
Ting Zhao; Lingli He; Lai Ping Wong; Shenglin Mei; Jun Xia; Yanxin Xu; Jonathan G. Van Vranken; Michael Mazzola; Lei Chen; Catherine Rhee; Tiancheng Fang; Tsuyoshi Fukushima; Leanne C. Sayles; Matthew Diaz; J. Alex B. Gibbons; Raul Mostoslavsky; Steven P. Gygi; Zhixun Dou; David B. Sykes; Ruslan I. Sadreyev; E. Alejandro Sweet-Cordero; David T. Scadden
Mutant IDH1 inhibition induces dsDNA sensing to activate tumor immunity

突变型IDH1抑制诱导dsDNA感应激活肿瘤免疫

Science
IF45.8
2024-01-010
OA
Meng‐Ju Wu; Hiroshi Kondo; Ashwin V. Kammula; Lei Shi; Yi Xiao; Sofiene Dhiab; Qin Xu; Chloe J. Slater; Omar I. Avila; Joshua Merritt; Hiroyuki Kato; Prabhat Kattel; Jonathan Sussman; Ilaria Gritti; Jason Eccleston; Yi Sun; Hyo Min Cho; Kira E. Olander; Takeshi Katsuda; Diana D. Shi; Milan R. Savani; Bailey C. Smith; James M. Cleary; Raúl Mostoslavsky; Vindhya Vijay; Yosuke Kitagawa; Hiroaki Wakimoto; Russell William Jenkins; Kathleen B. Yates; Jihye Paik; Anna M. Tassinari; Hatice Duygu Saatcioglu; Adriana E. Tron; Wilhelm Haas; Daniel P. Cahill; Samuel K. McBrayer; Robert T. Manguso; Nabeel M. Bardeesy
Inhibition of the proline metabolism rate-limiting enzyme P5CS allows proliferation of glutamine-restricted cancer cells
NATURE METABOLISM
IF20.8
2023-11-139
PRE
Linder, Samantha J.; Bernasocchi, Tiziano; Martinez-Pastor, Barbara; Sullivan, Kelly D.; Galbraith, Matthew D.; Lewis, Caroline A.; Ferrer, Christina M.; Boon, Ruben; Silveira, Giorgia G.; Cho, Hyo Min; Vidoudez, Charles; Shroff, Stuti; Oliveira-Costa, Joao P.; Ross, Kenneth N.; Massri, Rami; Matoba, Yusuke; Kim, Eugene; Rueda, Bo R.; Stott, Shannon L.; Gottlieb, Eyal; Espinosa, Joaquin M.; Mostoslavsky, Raul
NRF2 activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer (vol 35, pg 487, 2023)
CELL METABOLISM
IF30.9
2023-04-016
OA
Weiss-Sadan, Tommy; Ge, Maolin; Hayashi, Makiko; Gohar, Magdy; Yao, Cong-Hui; de Groot, Adriaan; Harry, Stefan; Carlin, Alexander; Fischer, Hannah; Shi, Lei; Wei, Ting -Yu; Adelmann, Charles H.; Wolf, Konstantin; Vornbaeumen, Tristan; Duerr, Benedikt R.; Takahashi, Mariko; Richter, Marianne; Zhang, Junbing; Yang, Tzu-Yi; Vijay, Vindhya; Fisher, David E.; Hata, Aaron N.; Haigis, Marcia C.; Mostoslavsky, Raul; Bardeesy, Nabeel; Papagiannakopoulos, Thales; Bar-Peled, Liron
Mammalian sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation
MOLECULAR AND CELLULAR BIOLOGY
IF2.7
2023-03-271.2K
OAAI
Lombard, David B.; Alt, Frederick W.; Cheng, Hwei-Ling; Bunkenborg, Jakob; Streeper, Ryan S.; Mostoslavsky, Raul; Kim, Jennifer; Yancopoulos, George; Valenzuela, David; Murphy, Andrew; Yang, Yinhua; Chen, Yaohui; Hirschey, Matthew D.; Bronson, Roderick T.; Haigis, Marcia; Guarente, Leonard P.; Farese, Robert V., Jr.; Weissman, Sherman; Verdin, Eric; Schwer, Bjoern
Sirtuin 6 inhibition protects against glucocorticoid-induced skeletal muscle atrophy by regulating IGF/PI3K/AKT signaling
NATURE COMMUNICATIONS
IF15.7
2022-09-1527
OAAI
Mishra, Sneha; Cosentino, Claudia; Tamta, Ankit Kumar; Khan, Danish; Srinivasan, Shalini; Ravi, Venkatraman; Abbotto, Elena; Arathi, Bangalore Prabhashankar; Kumar, Shweta; Jain, Aditi; Ramaian, Anand S.; Kizkekra, Shruti M.; Rajagopal, Raksha; Rao, Swathi; Krishna, Swati; Asirvatham-Jeyaraj, Ninitha; Haggerty, Elizabeth R.; Silberman, Dafne M.; Kurland, Irwin J.; Veeranna, Ravindra P.; Jayavelu, Tamilselvan; Bruzzone, Santina; Mostoslavsky, Raul; Sundaresan, Nagalingam R.
A non-dividing cell population with high pyruvate dehydrogenase kinase activity regulates metabolic heterogeneity and tumorigenesis in the intestine
NATURE COMMUNICATIONS
IF15.7
2022-03-2125
OAAI
Sebastian, Carlos; Ferrer, Christina; Serra, Maria; Choi, Jee-Eun; Ducano, Nadia; Mira, Alessia; Shah, Manasvi S.; Stopka, Sylwia A.; Perciaccante, Andrew J.; Isella, Claudio; Moya-Rull, Daniel; Vara-Messler, Marianela; Giordano, Silvia; Maldi, Elena; Desai, Niyati; Capen, Diane E.; Medico, Enzo; Cetinbas, Murat; Sadreyev, Ruslan, I; Brown, Dennis; Rivera, Miguel N.; Sapino, Anna; Breault, David T.; Agar, Nathalie Y. R.; Mostoslavsky, Raul
Long-term analysis of antibodies elicited by SPUTNIK V: A prospective cohort study in Tucuman, Argentina
LANCET REGIONAL HEALTH-AMERICAS
IF7.6
2022-02-0131
OAAI
Chahla, Rossana Elena; Tomas-Grau, Rodrigo Hernan; Cazorla, Silvia Ines; Ploper, Diego; Pingitore, Esteban Vera; Lopez, Monica Aguilar; Aznar, Patricia; Alcorta, Maria Elena; del Mar Velez, Eva Maria; Stagnetto, Agustin; Avila, Cesar Luis; Maldonado-Galdeano, Carolina; Socias, Sergio Benjamin; Heinze, Dar; Navarro, Silvia Adriana; Llapur, Conrado Juan; Costa, Dardo; Flores, Isolina; Edelstein, Alexis; Kowdle, Shreyas; Perandones, Claudia; Lee, Benhur; Apfelbaum, Gabriela; Mostoslavsky, Raul; Mostoslavsky, Gustavo; Perdigon, Gabriela; Chehin, Rosana Nieves
Graphical abstract

图形摘要

JCI INSIGHT
IF6.1
2022-01-2526
OAAI
Lubotzky, Asael; Zemmour, Hai; Neiman, Daniel; Gotkine, Marc; Loyfer, Netanel; Piyanzin, Sheina; Ochana, Bracha-Lea; Lehmann-Werman, Roni; Cohen, Daniel; Moss, Joshua; Magenheim, Judith; Loftus, Maureen F.; Brais, Lauren; Ng, Kimmie; Mostoslavsky, Raul; Wolpin, Brian M.; Zick, Aviad; Maoz, Myriam; Grinshpun, Albert; Kustanovich, Anatoli; Makranz, Chen; Cohen, Jonathan E.; Peretz, Tamar; Hubert, Ayala; Temper, Mark; Salah, Azzam; Avniel-Polak, Shani; Grozinsky-Glasberg, Simona; Spalding, Kirsty L.; Rokach, Ariel; Kaplan, Tommy; Glaser, Benjamin; Shemer, Ruth; Dor, Yuval
Elevated Humoral Immune Response to SARS-CoV-2 at High Altitudes Revealed by an Anti-RBD In-House ELISA
FRONTIERS IN MEDICINE
IF3
2021-10-147
OAAI
Tomas-Grau, Rodrigo Hernan; Ploper, Diego; avila, Cesar Luis; Vera Pingitore, Esteban; Maldonado Galdeano, Carolina; Chaves, Silvina; Socias, Sergio Benjamin; Stagnetto, Agustin; Navarro, Silvia Adriana; Chahla, Rossana Elena; Aguilar Lopez, Monica; Llapur, Conrado Juan; Aznar, Patricia; Alcorta, Maria Elena; Costas, Dardo; Flores, Isolina; Heinze, Dar; Apfelbaum, Gabriela; Mostoslavsky, Raul; Mostoslavsky, Gustavo; Cazorla, Silvia Ines; Perdigon, Gabriela del Valle; Chehin, Rosana
NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer
MOLECULAR CELL
IF16.6
2021-10-0126
OA
Guo, Hongsha; Golczer, Gabriel; Wittner, Ben S.; Langenbucher, Adam; Zachariah, Marcus; Dubash, Taronish D.; Hong, Xin; Comaills, Valentine; Burr, Risa; Ebright, Richard Y.; Horwitz, Elad; Vuille, Joanna A.; Hajizadeh, Soroush; Wiley, Devon F.; Reeves, Brittany A.; Zhang, Jia-min; Niederhoffer, Kira L.; Lu, Chenyue; Wesley, Benjamin; Ho, Uyen; Nieman, Linda T.; Toner, Mehmet; Vasudevan, Shobha; Zou, Lee; Mostoslavsky, Raul; Maheswaran, Shyamala; Lawrence, Michael S.; Harber, Daniel A.

研究方向

暂未获取到该数据
C
Carlos Sebastián
H 指数:29论文数:75被引数:5,476
R
Ruslan I. Sadreyev
H 指数:68论文数:402被引数:1.6万
F
Frederick W. Alt
H 指数:172论文数:642被引数:9.5万
B
Bárbara Martínez-Pastor
H 指数:16论文数:45被引数:2,310
C
Claudia Cosentino
H 指数:32论文数:100被引数:3,859
S
Sita Kugel
H 指数:11论文数:64被引数:1,162
C
Christina M. Ferrer
H 指数:17论文数:42被引数:1,875
K
Kenneth N. Ross
H 指数:43论文数:138被引数:1.7万
J
Jean‐Pierre Etchegaray
H 指数:19论文数:47被引数:1,839
L
Lei Zhong
H 指数:37论文数:149被引数:8,591