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Final clinical data of a phase 1 dose-escalation study of WVT078, a BCMA×CD3 bispecific antibody, alone and in combination with γ-secretase inhibitor WHG626 in patients with relapsed and/or refractory multiple myeloma WVT078（一种BCMA×CD3双特异性抗体）在复发和/或难治性多发性骨髓瘤患者中，单独及联合γ-分泌酶抑制剂WHG626的1期剂量递增研究的最终临床数据 Fredrik Schjesvold MD, PhD; Andrew Spencer MBBS, FRACP, FRCPA, DM; Yael C. Cohen MD; Enrique M. Ocio MD, PhD; Jordi Lopez-Pardo MD; Anna Maria Cafro MD; Natalie S. Callander MD; Jonathan L. Kaufman MD; Meera Mohan MD, MS; Martin Wermke MD; Noriko Doki PhD, MD; Rebecca Kan MPH; Pedro Milanez-Almeida PhD; Andrew Stein PhD; Gina Trabucco MSc; Stan Ye PhD; Karolina Kulec MSc; Romain Sechaud PhD; Souvik Banerjee PhD; Huiqin Zhong PhD; Clinton Lai MBChB, FFPM; Philipp J. Rauch MD; Marc S. Raab MD 分享 收藏
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Dual Targeting of Extramedullary Myeloma with Talquetamab and Teclistamab 用Talquetamab和Teclistamab双重靶向髓外骨髓瘤 Kumar, Shaji; Mateos, Maria-Victoria; Ye, Jing Christine; Atrash, Shebli; Magen, Hila; Quach, Hang; Chu, Michael P.; Trudel, Suzanne; Richter, Joshua; Rodriguez-Otero, Paula; Chuah, Hun; Gatt, Moshe; Medvedova, Eva; Raza, Shahzad; Yoon, Dok Hyun; Ishida, Tadao; Matous, Jeffrey V.; Rosinol, Laura; Onodera, Koichi; Scott, Emma; Heuck, Christoph; Zhang, Jenny; Henninger, Todd; O'Rourke, Lisa; Thakkar, Payal; Festa, Mariacristina; Huang, Lin; Zhou, Jiangxiu; Takamoto, Mikihiro; Pei, Lixia; Lu, Jiashen; Au, Nicholas; Krevvata, Maria; Usmani, Saad Z.; Cohen, Yael C. 分享 收藏
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A plain language summary of the CEPHEUS study of daratumumab plus bortezomib, lenalidomide, and dexamethasone for people with newly diagnosed multiple myeloma who are not expected to receive a stem cell transplant CEPHEUS研究的简明语言摘要：达拉木单抗联合硼替佐米、来那度胺和地塞米松，用于预期不接受干细胞移植的新诊断多发性骨髓瘤患者。 Usmani, Saad Z.; Facon, Thierry; Hungria, Vania; Bahlis, Nizar J.; Venner, Christopher P.; Braunstein, Marc; Pour, Ludek; Marti, Josep M.; Basu, Supratik; Cohen, Yael C.; Matsumoto, Morio; Suzuki, Kenshi; Hulin, Cyrille; Grosicki, Sebastian; Legiec, Wojciech; Beksac, Meral; Maiolino, Angelo; Takamatsu, Hiroyuki; Perrot, Aurore; Turgut, Mehmet; Ahmadi, Tahamtan; Liu, Weiping; Wang, Jianping; Chastain, Katherine; Vermeulen, Jessica; Krevvata, Maria; Lopez-Masi, Lorena; Carey, Jodi; Rowe, Melissa; Carson, Robin; Zweegman, Sonja 分享 收藏
Preclinical discovery and initial clinical data of WVT078, a BCMA x CD3 bispecific antibody (vol 17, pg 1349, 2023) WVT078的临床前发现及初步临床数据，一种BCMA x CD3双特异性抗体（卷17，页1349，2023） Raab, Marc S.; Cohen, Yael C.; Schjesvold, Fredrik; Aardalen, Kimberly; Oka, Adwait; Spencer, Andrew; Wermke, Martin; Souza, Anita D.; Kaufman, Jonathan L.; Cafro, Anna Maria; Ocio, Enrique M.; Doki, Noriko; Henson, Kristin; Trabucco, Gina; Carrion, Ana; Bender, Florent C.; Juif, Pierre-Eric; Fessehatsion, Adonai; Fan, Liqiong; Stonehouse, Jeffrey P.; Blankenship, John W.; Granda, Brian; De Vita, Serena; Lu, Haihui 分享 收藏
The Safety Profile of Pridopidine, a Novel Sigma-1 Receptor Agonist for the Treatment of Huntington's Disease 普瑞多匹定（Pridopidine）的安全特性，一种用于治疗亨廷顿病的新型σ1受体激动剂 Goldberg, Yigal Paul; Navon-Perry, Leehee; Cruz-Herranz, Andres; Chen, Kelly; Hecker-Barth, Gabriele; Spiegel, Katrin; Cohen, Yael; Niethammer, Martin; Tan, Andrew M.; Schuring, Henk; Geva, Michal; Hayden, Michael R. 分享 收藏
Functional Geriatric Assessment Tests Predict Toxicity Rates in Functional High Risk Myeloma Patients Treated with Daratumumab, Carfilzomib, Lenalidomide and Dexamethasone in a Prospective Clinical Trial 功能性老年评估测试可预测接受达鲁珠单抗、卡非佐米、来那度胺和地塞米松治疗的功能性高风险骨髓瘤患者的毒性发生率，在一项前瞻性临床试验中。 Shmuel, Ronit; Tellem, Rotem; Gatt, Moshe E.; Lavi, Noa; Ganzel, Chezi; Luttwak, Efrat; Chubar, Evgeni; Rouvio, Ory; Vaxman, Iuliana; Pasvolsky, Oren; Ballan, Mouna; Tadmor, Tamar; Nemets, Anatoly; Jarchowcky, Osnat; Shvetz, Olga; Lieba, Merav; Shpilberg, Ofer; Lowenton-Spier, Noa; Dally, Najib; Mazza, Irit Avivi; Cohen, Yael C. 分享 收藏
Biomarker Correlates and Clinical Activity of Cevostamab in Patients (pts) with Triple-Class Refractory Multiple Myeloma (MM) Who Have Received ≥1 Prior B-Cell Maturation Antigen (BCMA)-Targeted Bispecific Antibody (BsAb): Results from the Phase I/II CAMMA 2 Study 三药耐药多发性骨髓瘤（MM）患者中Cevostamab的生物标志物相关性及临床活性：这些患者已接受≥1种既往B细胞成熟抗原（BCMA）靶向双特异性抗体（BsAb）；结果来自I/II期CAMMA 2研究 Delforge, Michel; Richter, Joshua; Cohen, Yael C.; Corradini, Paolo; Sborov, Douglas W.; Lesokhin, Alexander M.; Berdeja, Jesus G.; Gatt, Moshe E.; Paris, Laura; Dachs, Laura Rosinol; Quach, Hang; Kanwar, Manisha; Catalani, Olivier; Sewpaul, Paresh; Wassner-Fritsch, Elisabeth; Mishra, Ameet; Trunzer, Kerstin; Kumar, Shaji 分享 收藏
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An Automated Insulin Delivery System with Automatic Meal Bolus Based on a Hand-Gesturing Algorithm Roy, Anirban; Grosman, Benyamin; Benedetti, Andrea; Engheta, Bahman; Miller, Diana; Laron-Hirsh, Maya; Cohen, Yael; Re, Roseline; Edd, Shannon N.; Vigersky, Robert; Cohen, Ohad; Tirosh, Amir 分享 收藏
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