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F

Frank Arnold

Memorial Sloan Kettering Cancer Center
H指数:25
被引数:3,894

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DKK3 Initially Preserves Acinar Integrity Through MEK-Fos Signaling, but Later Switches to an Oncogenic Role in Pancreatic Cancer

DKK3通过MEK-Fos信号通路最初保持腺泡完整性，但随后转变为在胰腺癌中的致癌作用。

Advanced Science
IF14.1
2025-10-280
OAAI
Dharini Srinivasan; Elodie Roger; Lukas Perkhofer; Eleni Zimmer; Thomas F.E. Barth; Julia P. Mosler; Anna Härle; Stephanie E. Weissinger; Nadine T. Gaisa; Peter Möller; Nico Fischer; Chantal Allgöwer; J.-Matthias Löhr; Dirk Grimm; Thomas Seufferlein; Stefan Liebau; Ninel Azoitei; Michael K. Melzer; Frank Arnold; Johann Gout; Alexander Kleger
Phase 1 trial evaluating safety and pharmacokinetics of HIV-1 broadly neutralizing mAbs 10E8VLS and VRC07-523LS
JCI INSIGHT
IF6.1
2024-04-082
OA
Awan, Seemal F.; Pegu, Amarendra; Strom, Larisa; Carter, Cristina A.; Hendel, Cynthia S.; Holman, LaSonji A.; Costner, Pamela J.; Trofymenko, Olga; Dyer, Renunda; Gordon, Ingelise J.; Rothwell, Ro Shauna S.; Hickman, Somia P.; Conan-Cibotti, Michelle; Doria-Rose, Nicole A.; Lin, Bob C.; O'Connell, Sarah; Narpala, Sandeep R.; Almasri, Cassandra G.; Liu, Cuiping; Ko, Sungyoul; Kwon, Young D.; Namboodiri, Aryan M.; Pandey, Janardan P.; Arnold, Frank J.; Carlton, Kevin; Gall, Jason G.; Kwong, Peter D.; Capparelli, Edmund, V; Bailer, Robert T.; Mcdermott, Adrian B.; Chen, Grace L.; Koup, Richard A.; Mascola, John R.; Coates, Emily E.; Ledgerwood, Julie E.; Gaudinski, Martin R.
Organoids at the PUB: The Porcine Urinary Bladder Serves as a Pancreatic Niche for Advanced Cancer Modeling
ADVANCED HEALTHCARE MATERIALS
IF9.6
2022-02-1810
OAAI
Melzer, Michael Karl; Breunig, Markus; Arnold, Frank; Wezel, Felix; Azoitei, Anca; Roger, Elodie; Krueger, Jana; Merkle, Jessica; Schuette, Lena; Resheq, Yazid; Hanle, Mark; Zehe, Viktor; Zengerling, Friedemann; Azoitei, Ninel; Klein, Lukas; Penz, Frederike; Singh, Shiv K.; Seufferlein, Thomas; Hohwieler, Meike; Bolenz, Christian; Gunes, Cagatay; Gout, Johann; Kleger, Alexander
Safety and immunogenicity of a ferritin nanoparticle H2 influenza vaccine in healthy adults: a phase 1 trial
NATURE MEDICINE
IF50
2022-02-0397
OAAI
Houser, Katherine, V; Chen, Grace L.; Carter, Cristina; Crank, Michelle C.; Nguyen, Thuy A.; Florez, Maria Claudia Burgos; Berkowitz, Nina M.; Mendoza, Floreliz; Hendel, Cynthia Starr; Gordon, Ingelise J.; Coates, Emily E.; Vazquez, Sandra; Stein, Judy; Case, Christopher L.; Lawlor, Heather; Carlton, Kevin; Gaudinski, Martin R.; Strom, Larisa; Hofstetter, Amelia R.; Liang, C. Jason; Narpala, Sandeep; Hatcher, Christian; Gillespie, Rebecca A.; Creanga, Adrian; Kanekiyo, Masaru; Raab, Julie E.; Andrews, Sarah F.; Zhang, Yi; Yang, Eun Sung; Wang, Lingshu; Leung, Kwanyee; Kong, Wing-Pui; Freyn, Alec W.; Nachbagauer, Raffael; Palese, Peter; Bailer, Robert T.; McDermott, Adrian B.; Koup, Richard A.; Gall, Jason G.; Arnold, Frank; Mascola, John R.; Graham, Barney S.; Ledgerwood, Julie E.
Functional Genomic Screening During Somatic Cell Reprogramming Identifies DKK3 as a Roadblock of Organ Regeneration

体细胞重编程过程中的功能基因组筛选将DKK3鉴定为器官再生的路障

ADVANCED SCIENCE
IF14.1
2021-05-138
OA
Arnold, Frank; Mahaddalkar, Pallavi U.; Kraus, Johann M.; Zhong, Xiaowei; Bergmann, Wendy; Srinivasan, Dharini; Gout, Johann; Roger, Elodie; Beutel, Alica K.; Zizer, Eugen; Tharehalli, Umesh; Daiss, Nora; Russell, Ronan; Perkhofer, Lukas; Oellinger, Rupert; Lin, Qiong; Azoitei, Ninel; Weiss, Frank-Ulrich; Lerch, Markus M.; Liebau, Stefan; Katz, Sarah-Fee; Lechel, Andre; Rad, Roland; Seufferlein, Thomas; Kestler, Hans A.; Ott, Michael; Sharma, Amar Deep; Hermann, Patrick C.; Kleger, Alexander
RINT1 Regulates SUMOylation and the DNA Damage Response to Preserve Cellular Homeostasis in Pancreatic Cancer
CANCER RESEARCH
IF16.6
2021-02-028
OA
Arnold, Frank; Gout, Johann; Wiese, Heike; Weissinger, Stephanie E.; Roger, Elodie; Perkhofer, Lukas; Walter, Karolin; Scheible, Jeanette; Bozzo, Caterina Prelli; Lechel, Andre; Ettrich, Thomas J.; Azoitei, Ninel; Hao, Li; Fuerstberger, Axel; Kaminska, Ewa K.; Sparrer, Konstantin M. J.; Rasche, Volker; Wiese, Sebastian; Kestler, Hans A.; Moller, Peter; Seufferlein, Thomas; Frappart, Pierre-Olivier; Kleger, Alexander
Immune Monitoring Reveals Fusion Peptide Priming to Imprint Cross-Clade HIV-Neutralizing Responses with a Characteristic Early B Cell Signature
CELL REPORTS
IF6.9
2020-08-0120
OAAI
Cheng, Cheng; Duan, Hongying; Xu, Kai; Chuang, Gwo-Yu; Corrigan, Angela R.; Geng, Hui; O'Dell, Sijy; Ou, Li; Chambers, Michael; Changela, Anita; Chen, Xuejun; Foulds, Kathryn E.; Sarfo, Edward K.; Jafari, Alexander J.; Hill, Kurt R.; Kong, Rui; Liu, Kevin; Todd, John P.; Tsybovsky, Yaroslav; Verardi, Raffaello; Wang, Shuishu; Wang, Yiran; Wu, Winston; Zhou, Tongqing; Arnold, Frank J.; Doria-Rose, Nicole A.; Koup, Richard A.; McDermott, Adrian B.; Scorpio, Diana G.; Worobey, Michael; Shapiro, Lawrence; Mascola, John R.; Kwong, Peter D.
Pancreatic cancer-derived organoids - a disease modeling tool to predict drug response

胰腺癌衍生的类器官-预测药物反应的疾病建模工具

UNITED EUROPEAN GASTROENTEROLOGY JOURNAL
IF6.7
2020-06-0161
OAAI
Frappart, Pierre-Olivier; Walter, Karolin; Gout, Johann; Beutel, Alica K.; Morawe, Mareen; Arnold, Frank; Breunig, Markus; Barth, Thomas F. E.; Marienfeld, Ralf; Schulte, Lucas; Ettrich, Thomas; Hackert, Thilo; Svinarenko, Michael; Roesler, Reinhild; Wiese, Sebastian; Wiese, Heike; Perkhofer, Lukas; Mueller, Martin; Lechel, Andre; Sainz, Bruno, Jr.; Hermann, Patrick C.; Seufferlein, Thomas; Kleger, Alexander

研究方向

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A
Alexander Kleger
H 指数:45论文数:386被引数:7,619
T
Thomas Seufferlein
H 指数:78论文数:868被引数:3.5万
J
Johann Gout
H 指数:18论文数:112被引数:1,142
L
Lukas Perkhofer
H 指数:25论文数:253被引数:2,411
É
Élodie Roger
H 指数:9论文数:57被引数:587
Q
Q. Paula Lei
H 指数:11论文数:60被引数:576
N
Ninel Azoitei
H 指数:22论文数:109被引数:3,345
R
Richard A. Koup
H 指数:131论文数:550被引数:6.9万
J
John R. Mascola
H 指数:152论文数:781被引数:8.4万
V
Vera B. Ivleva
H 指数:14论文数:60被引数:888