Sandra Heller

ulm university

H指数:24

被引数:2,587

个人简介

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教育背景

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工作经历

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荣誉奖项

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An oncogenic KRAS-driven secretome involving TNFα promotes niche preparation prior to pancreatic cancer onset

涉及tnf α 的致癌KRAS驱动的分泌蛋白组促进胰腺癌发病前的利基准备

Molecular Cancer

IF33.9

2026-02-030

OAAI

Chantal Allgöwer; Medhanie A. Mulaw; James Nagai; Sandra Wiedenmann; Elena Anne Ringel; Benedetta Ferrara; Lorenzo Piemonti; Tengku Ibrahim Maulana; Luisa T. Ferreira; Adam Flinders; Claudia Teufel; Leon Reichardt; Paul B. Lopatta; Dharini Srinivasan; Anton Lahusen; Thomas Seufferlein; Nadine Therese Gaisa; Annika Beck; Jessica Lindenmayer; Michael K. Melzer; Eleni Zimmer; Elodie Roger; Sandra Heller; J.-Mathias Löhr; Stefan Liebau; Peter Loskill; Yuan-Na Lin; Paolo Riccardo Camisa; Claus Jorgensen; Stefano Crippa; Matthias Meier; Meike Hohwieler; Ivan G. Costa; Markus Breunig; Alexander Kleger

Host factor PLAC8 is required for pancreas infection by SARS-CoV-2

COMMUNICATIONS MEDICINE

IF6.3

2025-02-030

A ONECUT1 regulatory, non-coding region in pancreatic development and diabetes

CELL REPORTS

IF6.9

2024-11-011

OAAI

Single-cell profiling of GP2-enriched pancreatic progenitors to simultaneously create acinar, ductal, and endocrine organoids

GP2-enriched胰腺祖细胞的单细胞分析，以同时创建腺泡，导管和内分泌类器官

THERANOSTICS

IF13.3

2023-01-016

OAAI

Functional Genomic Screening in Human Pluripotent Stem Cells Reveals New Roadblocks in Early Pancreatic Endoderm Formation

CELLS

IF5.2

2022-02-082

OAAI

Spike residue 403 affects binding of coronavirus spikes to human ACE2

NATURE COMMUNICATIONS

IF15.7

2021-11-2527

OAAI

Transcriptional changes and the role of ONECUT1 in hPSC pancreatic differentiation

COMMUNICATIONS BIOLOGY

IF5.1

2021-11-1720

OAAI

Mutations and variants of ONECUT1 in diabetes

NATURE MEDICINE

IF50

2021-10-1830

Philippi, Anne; Heller, Sandra; Costa, Ivan G.; Senee, Valerie; Breunig, Markus; Li, Zhijian; Kwon, Gino; Russell, Ronan; Illing, Anett; Lin, Qiong; Hohwieler, Meike; Degavre, Anne; Zalloua, Pierre; Liebau, Stefan; Schuster, Michael; Krumm, Johannes; Zhang, Xi; Geusz, Ryan; Benthuysen, Jacqueline R.; Wang, Allen; Chiou, Joshua; Gaulton, Kyle; Neubauer, Heike; Simon, Eric; Klein, Thomas; Wagner, Martin; Nair, Gopika; Besse, Celine; Dandine-Roulland, Claire; Olaso, Robert; Deleuze, Jean-Francois; Kuster, Bernhard; Hebrok, Matthias; Seufferlein, Thomas; Sander, Maike; Boehm, Bernhard O.; Oswald, Franz; Nicolino, Marc; Julier, Cecile; Kleger, Alexander

IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro

NATURE COMMUNICATIONS

IF15.7

2021-07-28122

OAAI

Bozzo, Caterina Prelli; Nchioua, Rayhane; Volcic, Meta; Koepke, Lennart; Krueger, Jana; Schuetz, Desiree; Heller, Sandra; Stuerzel, Christina M.; Kmiec, Dorota; Conzelmann, Carina; Mueller, Janis; Zech, Fabian; Braun, Elisabeth; Gross, Ruediger; Wettstein, Lukas; Weil, Tatjana; Weiss, Johanna; Diofano, Federica; Alfonso, Armando A. Rodriguez; Wiese, Sebastian; Sauter, Daniel; Muench, Jan; Goffinet, Christine; Catanese, Alberto; Schoen, Michael; Boeckers, Tobias M.; Stenger, Steffen; Sato, Kei; Just, Steffen; Kleger, Alexander; Sparrer, Konstantin M. J.; Kirchhoff, Frank

Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells

源自人多能干细胞的胰腺导管类器官的可塑性和发育异常的建模

CELL STEM CELL

IF20.4

2021-06-0168

OAAI

Breunig, Markus; Merkle, Jessica; Wagner, Martin; Melzer, Michael K.; Barth, Thomas F. E.; Engleitner, Thomas; Krumm, Johannes; Wiedenmann, Sandra; Cohrs, Christian M.; Perkhofer, Lukas; Jain, Gaurav; Kruger, Jana; Hermann, Patrick C.; Schmid, Maximilian; Madacsy, Tamara; Varga, Arpad; Griger, Joscha; Azoitei, Ninel; Mueller, Martin; Wessely, Oliver; Robey, Pamela G.; Heller, Sandra; Dantes, Zahra; Reichert, Maximilian; Guenes, Cagatay; Bolenz, Christian; Kuhn, Florian; Maleth, Jozsef; Speier, Stephan; Liebau, Stefan; Sipos, Bence; Kuster, Bernhard; Seufferlein, Thomas; Rad, Roland; Meier, Matthias; Hohwieler, Meike; Kleger, Alexander

Interpreting type 1 diabetes risk with genetics and single-cell epigenomics

Nature

IF48.5

2021-05-190

PREAI

Human Pluripotent Stem Cells Go Diabetic: A Glimpse on Monogenic Variants

FRONTIERS IN ENDOCRINOLOGY

IF4.6

2021-05-176

OAAI

SARS-CoV-2 infects and replicates in cells of the human endocrine and exocrine pancreas

NATURE METABOLISM

IF20.8

2021-02-03370

OAAI

Mueller, Janis A.; Gross, Ruediger; Conzelmann, Carina; Krueger, Jana; Merle, Uta; Steinhart, Johannes; Weil, Tatjana; Koepke, Lennart; Bozzo, Caterina Prelli; Read, Clarissa; Fois, Giorgio; Eiseler, Tim; Gehrmann, Julia; van Vuuren, Joanne; Wessbecher, Isabel M.; Frick, Manfred; Costa, Ivan G.; Breunig, Markus; Gruener, Beate; Peters, Lynn; Schuster, Michael; Liebau, Stefan; Seufferlein, Thomas; Stenger, Steffen; Stenzinger, Albrecht; MacDonald, Patrick E.; Kirchhoff, Frank; Sparrer, Konstantin M. J.; Walther, Paul; Lickert, Heiko; Barth, Thomas F. E.; Wagner, Martin; Muench, Jan; Heller, Sandra; Kleger, Alexander

Drug Inhibition of SARS-CoV-2 Replication in Human Pluripotent Stem Cell-Derived Intestinal Organoids

药物抑制人多能干细胞衍生的肠类器官中的SARS-CoV-2复制

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY

IF7.4

2021-01-0178

OAAI

Bacterial TLR4 and NOD2 signaling linked to reduced mitochondrial energy function in active inflammatory bowel disease

GUT MICROBES

IF11

2019-05-0714

OAAI

Pancreatic Progenitors and Organoids as a Prerequisite to Model Pancreatic Diseases and Cancer