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Mutational Landscape and Depth of Response in Patients with Acute Myeloid Leukemia (AML) Treated with Magrolimab in Combination with Venetoclax and Azacitidine Compared to Placebo 急性髓系白血病（AML）患者接受magrolimab联合venetoclax和azacitidine治疗与安慰剂治疗的突变景观和应答深度比较 Johnson, Lisa D. S.; Tang, Shan; Zhang, Yajia; Metzner, Marlen; Aviles, Lisa; Kavelaars, Francois; Morrow, Eyelet; Vitters, Damien; Caldwell, Kenneth; Valk, Peter J. M.; Vyas, Paresh 分享 收藏
Hematopoietic stem cell heterogeneity and age-associated platelet bias are evolutionarily conserved Aksoez, Merve; Gafencu, Grigore-Aristide; Stoilova, Bilyana; Buono, Mario; Zhang, Ying; Turkalj, Sven; Meng, Yiran; Jakobsen, Niels Asger; Metzner, Marlen; Clark, Sally-Ann; Beveridge, Ryan; Thongjuea, Supat; Vyas, Paresh; Nerlov, Claus 分享 收藏
Selective advantage of mutant stem cells in human clonal hematopoiesis is associated with attenuated response to inflammation and aging 突变干细胞在人类克隆造血中的选择性优势与对炎症和衰老的反应减弱有关 Jakobsen, Niels Asger; Turkalj, Sven; Zeng, Andy G. X.; Stoilova, Bilyana; Metzner, Marlen; Rahmig, Susann; Nagree, Murtaza S.; Shah, Sayyam; Moore, Rachel; Usukhbayar, Batchimeg; Salazar, Mirian Angulo; Gafencu, Grigore-Aristide; Kennedy, Alison; Newman, Simon; Kendrick, Benjamin J. L.; Taylor, Adrian H.; Afinowi-Luitz, Rasheed; Gundle, Roger; Watkins, Bridget; Wheway, Kim; Beazley, Debra; Murison, Alex; Aguilar-Navarro, Alicia G.; Flores-Figueroa, Eugenia; Dakin, Stephanie G.; Carr, Andrew J.; Nerlov, Claus; Dick, John E.; Xie, Stephanie Z.; Vyas, Paresh 分享 收藏
GTAC enables parallel genotyping of multiple genomic loci with chromatin accessibility profiling in single cells Turkalj, Sven; Jakobsen, Niels Asger; Groom, Angus; Metzner, Marlen; Riva, Simone G.; Gur, E. Ravza; Usukhbayar, Batchimeg; Salazar, Mirian Angulo; Hentges, Lance D.; Mickute, Gerda; Clark, Kevin; Sopp, Paul; Davies, James O. J.; Hughes, Jim R.; Vyas, Paresh 分享 收藏
A shared somatic translocation involving CUX1 in monozygotic twins as an early driver of AMKL in Down syndrome Bache, Iben; Wadt, Karin; Mehrjouy, Mana M.; Rossing, Maria; Ostrup, Olga; Byrjalsen, Anna; Tommerup, Niels; Metzner, Marlen; Vyas, Paresh; Schmiegelow, Kjeld; Lausen, Birgitte; Andersen, Mette K. 分享 收藏
A Recurrent Activating Missense Mutation in Waldenstrom Macroglobulinemia Affects the DNA Binding of the ETS Transcription Factor SPI1 and Enhances Proliferation Roos-Weil, Damien; Decaudin, Camille; Armand, Marine; Della-Valle, Veronique; Diop, Mboyba K.; Ghamlouch, Hussein; Ropars, Virginie; Herate, Cecile; Lara, Diane; Durot, Eric; Haddad, Rima; Mylonas, Elena; Damm, Frederik; Pflumio, Francoise; Stoilova, Bilyana; Metzner, Marlen; Elemento, Olivier; Dessen, Philippe; Camara-Clayette, Valerie; Cosset, Francois-Loic; Verhoeyen, Els; Leblond, Veronique; Ribrag, Vincent; Cornillet-Lefebvre, Pascale; Rameau, Philippe; Azars, Nabih; Charlottes, Frederic; More, Pierre; Charbonnier, Jean-Baptiste; Vyas, Paresh; Mercher, Thomas; Aoufouchi, Said; Droin, Nathalie; Guillouf, Christet; Nguyen-Khac, Florence; Bernard, Olivier A. 分享 收藏
Clonal heterogeneity of acute myeloid leukemia treated with the IDH2 inhibitor enasidenib Quek, Lynn; David, Muriel D.; Kennedy, Alison; Metzner, Marlen; Amatangelo, Michael; Shih, Alan; Stoilova, Bilyana; Quivoron, Cyril; Heiblig, Mael; Willekens, Christophe; Saada, Veronique; Alsafadi, Samar; Vijayabaskar, M. S.; Peniket, Andy; Bernard, Oliver A.; Agresta, Sam; Yen, Katharine; MacBeth, Kyle; Stein, Eytan; Vassiliou, George S.; Levine, Ross; De Botton, Stephane; Thakurte, Anjan; Penard-Lacronique, Virginie; Vyas, Paresh 分享 收藏
Mutational analysis of disease relapse in patients allografted for acute myeloid leukemia Quek, Lynn; Ferguson, Paul; Metzner, Marlen; Ahmed, Ikhlaaq; Kennedy, Alison; Garnett, Catherine; Jeffries, Sally; Walter, Claudia; Piechocki, Kim; Timbs, Adele; Danby, Robert; Raghavan, Manoj; Peniket, Andrew; Griffiths, Mike; Bacon, Andrew; Ward, Janice; Wheatley, Keith; Vyas, Paresh; Craddock, Charles 分享 收藏
Genetically distinct leukemic stem cells in human CD34- acute myeloid leukemia are arrested at a hemopoietic precursor-like stage Quek, Lynn; Otto, Georg W.; Garnett, Catherine; Lhermitte, Ludovic; Karamitros, Dimitris; Stoilova, Bilyana; Lau, I-Jun; Doondeea, Jessica; Usukhbayar, Batchimeg; Kennedy, Alison; Metzner, Marlen; Goardon, Nicolas; Ivey, Adam; Allen, Christopher; Gale, Rosemary; Davies, Benjamin; Sternberg, Alexander; Killick, Sally; Hunter, Hannah; Cahalin, Paul; Price, Andrew; Carr, Andrew; Griffiths, Mike; Virgo, Paul; Mackinnon, Stephen; Grimwade, David; Freeman, Sylvie; Russell, Nigel; Craddock, Charles; Mead, Adam; Peniket, Andrew; Porcher, Catherine; Vyas, Paresh 分享 收藏
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