Felix J. Hartmann - Publications, H-index & Citations

Felix J. Hartmann

systems immunology and single-cell biology

27H指数

104论文数

6.1K被引数

收录论文 39

发表时间

FGFR2 fusion-driven cholangiocarcinoma is characterized by a distinct neutrophil-enriched tumor microenvironment in a syngeneic murine model FGFR2融合驱动的胆管癌在同基因小鼠模型中具有独特的富集中性粒细胞的肿瘤微环境

JHEP Reports

IF7.5

2026-07-21

OAAI

Nugzar Lekiashvili; Trinh Kieu Dinh; Alexander Olkus; Yu-Le Wu; Chun-Shan Liu; Daria Komkova; Albrecht Stenzinger; Felix J. Hartmann; Thomas Longerich; Michael T. Dill

Temporal and spatial composition of the tumor microenvironment predicts response to immune checkpoint inhibition in metastatic TNBC 肿瘤微环境的时空组成可预测转移性TNBC对免疫检查点抑制的反应

Nature Cancer

IF28.5

2026-02-18

PREAI

Noah F. Greenwald; Iris Nederlof; Cameron Sowers; Daisy Yi Ding; Seongyeol Park; Alex Kong; Kathleen E. Houlahan; Sricharan Reddy Varra; Manon de Graaf; Veerle Geurts; Candace C. Liu; Jolene S. Ranek; Leonie Voorwerk; Michiel de Maaker; Adam Kagel; Erin McCaffrey; Aziz Khan; Christine Yiwen Yeh; Christine Camacho Fullaway; Zumana Khair; Brennan G. Simon; Yunhao Bai; Hadeesha Piyadasa; Tyler Risom; Alea Delmastro; Felix J. Hartmann; Lise Mangiante; Cristina Sotomayor-Vivas; Sean C. Bendall; Ton N. Schumacher; Zhicheng Ma; Marc Bosse; Marc J. van de Vijver; Robert Tibshirani; Hugo M. Horlings; Christina Curtis; Marleen Kok; Michael Angelo

A microenvironment-determined risk continuum refines subtyping in meningioma and reveals determinants of machine learning-based tumor classification 微环境确定的风险连续体可改善脑膜瘤的亚型，并揭示基于机器学习的肿瘤分类的决定因素

Nature Genetics

IF29

2026-02-09

OAAI

Sybren L. N. Maas; Yiheng Tang; Eric Stutheit-Zhao; Ramin Rahmanzade; Christina Blume; Thomas Hielscher; Ferdinand Zettl; Salvatore Benfatto; Domenico Calafato; Martin Sill; Jasim Kada Benotmane; Yahaya A. Yabo; Felix Behling; Abigail Suwala; Helin Kardo; Michael Ritter; Matthieu Peyre; Roman Sankowski; Konstantin Okonechnikov; Philipp Sievers; Areeba Patel; David Reuss; Mirco J. Friedrich; Damian Stichel; Daniel Schrimpf; Thierry P. P. Van den Bosch; Katja Beck; Hans-Georg Wirsching; Gerhard Jungwirth; C. Oliver Hanemann; Katrin Lamszus; Nima Etminan; Andreas Unterberg; Christian Mawrin; Marc Remke; Olivier Ayrault; Peter Lichter; Guido Reifenberger; Michael Platten; Tim Kacprowski; Markus List; Josch K. Pauling; Jan Baumbach; Till Milde; Rachel Grossmann; Zvi Ram; Miriam Ratliff; Jan-Philipp Mallm; Marian C. Neidert; Eelke M. Bos; Marco Prinz; Michael Weller; Till Acker; Felix J. Hartmann; Matthias Preusser; Ghazaleh Tabatabai; Christel Herold-Mende; Sandro M. Krieg; David T. W. Jones; Stefan M. Pfister; Wolfgang Wick; Michel Kalamarides; Andreas von Deimling; Dieter Henrik Heiland; Volker Hovestadt; Moritz Gerstung; Matthias Schlesner; Felix Sahm

Activated ATF6α is a hepatic tumour driver restricting immunosurveillance 激活的ATF6α 是限制免疫监视的肝肿瘤驱动因素

Nature

IF48.5

2026-02-04

OAAI

Xin Li; Cynthia Lebeaupin; Aikaterini Kadianaki; Clementine Druelle-Cedano; Niklas Vesper; Charlotte Rennert; Júlia Huguet-Pradell; Borja Gomez Ramos; Chaofan Fan; Robert Stefan Piecyk; Laimdota Zizmare; Pierluigi Ramadori; Luqing Li; Lukas Frick; Menjie Qiu; Cangang Zhang; Luiza Martins Nascentes Melo; Vikas Prakash Ranvir; Peng Shen; Johannes Hanselmann; Jan Kosla; Mirian Fernández-Vaquero; Mihael Vucur; Praveen Baskaran; Xuanwen Bao; Olivia I. Coleman; Yingyue Tang; Miray Cetin; Zhouji Chen; Insook Jang; Stefania Del Prete; Mohammad Rahbari; Peng Zhang; Timothy V. Pham; Yushan Hou; Aihua Sun; Li Gu; Laura C. Kim; Ulrike Rothermel; Danijela Heide; Adnan Ali; Suchira Gallage; Nana Talvard-Balland; Marta Piqué-Gili; Albert Gris-Oliver; Alessio Bevilacqua; Lisa Schlicker; Alec Duffey; Kristian Unger; Marta Szydlowska; Jenny Hetzer; Duncan T. Odom; Tim Machauer; Daniele Bucci; Pooja Sant; Jun-Hoe Lee; Jonas Rösler; Sven W. Meckelmann; Johannes Schreck; Sue Murray; M. Celeste Simon; Sven Nahnsen; Almut Schulze; Ping-Chih Ho; Manfred Jugold; Kai Breuhahn; Jan-Philipp Mallm; Peter Schirmacher; Susanne Roth; Nuh Rahbari; Darjus F. Tschaharganeh; Stephanie Roessler; Benjamin Goeppert; Bertram Bengsch; Geoffroy Andrieux; Melanie Boerries; Nisar P. Malek; Marco Prinz; Achim Weber; Robert Zeiser; Pablo Tamayo; Peter Bronsert; Konrad Kurowski; Robert Thimme; Detian Yuan; Rafael Carretero; Tom Luedde; Roser Pinyol; Felix J. Hartmann; Michael Karin; Alpaslan Tasdogan; Christoph Trautwein; Moritz Mall; Maike Hofmann; Josep M. Llovet; Dirk Haller; Randal J. Kaufman; Mathias Heikenwälder

DHODH as a Targetable Metabolic Achilles' Heel for chemo-resistant B-ALL DHODH作为抗化疗b-all的可靶向代谢致命弱点

Blood

IF23.1

2026-01-29

PREAI

Yuxuan Liu; Haowen Jiang; Jingjing Liu; Lucille Stuani; Milton Merchant; Astraea Jager; Abhishek Koladiya; Ti-Cheng Chang; Pablo Domizi; Jolanda Sarno; Ao Wang; Timothy Keyes; Dorra Jedoui; Jodie Meng; Felix Hartmann; Ruida Hou; Carol Fries; Chiara Pirillo; Qingsong Gao; Ilaria Iacobucci

MACHINE LEARNING AND MULTI-OMIC ANALYSIS IDENTIFY A MICROENVIRONMENT-DRIVEN MENINGIOMA RISK CONTINUUM UNDERLYING MOLECULAR CLASSIFICATIONS 机器学习和多组学分析识别出一种由微环境驱动的、与分子分类相关的脑膜瘤风险连续体

NEURO-ONCOLOGY

IF13.4

2025-11-01

PREAI

Maas, Sybren; Tang, Yiheng; Stutheit-Zhao, Eric; Rahmanzade, Ramin; Hielscher, Thomas; Zettl, Ferdinand; Benfatto, Salvatore; Calafato, Domenico; Sill, Martin; Benotmane, Jasim Kada; Yabo, Yahaya; Peyre, Matthieu; Sankowski, Roman; Okonechnikov, Konstantin; Sievers, Philip; Patel, Areeba; Reuss, David; Hanemann, Oliver; Lamszus, Katrin; Etminan, Nima; Unterberg, Andreas; Mawrin, Christian; Grossmann, Rachel; Ram, Zvi; Ratliff, Miriam; Neidert, Marian; Bos, Eelke; Prinz, Marco; Weller, Michael; Acker, Till; Hartmann, Felix; Preusser, Matthias; Tabatabai, Ghazaleh; Herold-Mende, Christel; Krieg, Sandro; Jones, David; Pfister, Stefan; Wick, Wolfgang; Kalamarides, Michel; Von Deimling, Andreas; Heiland, Dieter Henrik; Hovestadt, Volker; Gerstung, Moritz; Schlesner, Matthias; Sahm, Felix

Spatial Immunometabolism: Integrating Technologies to Decode Cellular Metabolism in Tissues

EUROPEAN JOURNAL OF IMMUNOLOGY

IF3.7

2025-11-01

OAAI

Hartmann, Felix J.

Spatial proteomics of Alzheimer’s disease-specific human microglial states 阿尔茨海默病特异性人类小胶质细胞状态的空间蛋白质组学

Nature Immunology

IF27.6

2025-07-22

PREAI

Dunja Mrdjen; Bryan J. Cannon; Meelad Amouzgar; YeEun Kim; Candace Liu; Kausalia Vijayaragavan; Christine Camacho; Angie Spence; Erin F. McCaffrey; Anusha Bharadwaj; Dmitry Tebaykin; Syed Bukhari; Marc Bosse; Felix J. Hartmann; Adam Kagel; John Paul Oliveria; Koya Yakabi; Geidy E. Serrano; Maria M. Corrada; Claudia H. Kawas; Robert Tibshirani; Thomas G. Beach; M. Ryan Corces; Will Greenleaf; R. Michael Angelo; Thomas Montine; Sean C. Bendall

New Atomic Mass Tags for Enhanced Multiplexing Capability of Multiplexed Ion Beam Imaging Time-of-Flight (MIBI-TOF) Analysis 新型原子质量标签用于增强多重离子束成像飞行时间（MIBI-TOF）分析的多重检测能力

ANALYTICAL CHEMISTRY

IF6.7

2025-04-14

PREAI

Kumar, Rashmi; Hartmann, Felix J.; Favaro, Patricia; Ho, Daniel; Bruce, Trevor; Goldston, Mako; Spence, Angie; McCaffrey, Erin F.; Bendall, Sean C.; Angelo, Michael

Isolation of a tumor neoantigen specific CD8+TCR from a skin biopsy of a vaccination site 从疫苗接种部位的皮肤活检中分离出肿瘤新抗原特异性CD8 TCR

ONCOIMMUNOLOGY

IF6.3

2025-02-04

OAAI

Roberti, Maria Paula; Charoentong, Pornpimol; Lyu, Yanhong; Meyer, Marten; Eichmueller, Stefan B.; Schmidt, Patrick; Momburg, Frank; Cetin, Miray; Hartmann, Felix; Valous, Nektarios A.; Stenzinger, Albrecht; Michel, Laura; Lichter, Peter; Schneeweiss, Andreas; Thewes, Verena; Fremd, Carlo; Zoernig, Inka; Jaeger, Dirk

SPATIAL PROFILING OF THE MYELOID COMPARTMENT IN MENINGIOMA REVEALS DISTINCT PHENOTYPIC HETEROGENEITY ACROSS METHYLATION CLASSES

NEURO-ONCOLOGY

IF13.4

2024-10-17

PREAI

Calafato, D.; Tang, Y.; Rukhovich, G.; Patel, B.; Suwala, A.; Sahm, F.; Gerstung, M.; Hartmann, F.

Autophagy counters inflammation-driven glycolytic impairment in aging hematopoietic stem cells 自噬对抗衰老造血干细胞中炎症驱动的糖酵解障碍

CELL STEM CELL

IF20.4

2024-07-01

OAAI

V. Dellorusso, Paul; Proven, Melissa A.; Calero-Nieto, Fernando J.; Wang, Xiaonan; Mitchell, Carl A.; Hartmann, Felix; Amouzgar, Meelad; Favaro, Patricia; Devilbiss, Andrew; Swann, James W.; Ho, Theodore T.; Zhao, Zhiyu; Bendall, Sean C.; Morrison, Sean; Gottgens, Berthold; Passegue, Emmanuelle

B cell immunology predict response and survival in PD-1/PD-L1 targeting immune checkpoint inhibition of metastatic breast cancer

CANCER RESEARCH

IF16.6

2024-05-02

PREAI

Fremd, Carlo; Schulze, Markus; Cetin, Miray; Boehm, Hannah; Lenoire, Benedicte; Akilli-Oeztuerk, Oezlem; Zornig, Inka; Charoentong, Pornpimol; Lyu, Yanhong; Hubschmann, Daniel; Hubschmann, Daniel; Kommoss, Felix; Thewes, Verena; Schneeweiss, Andreas; Zapatka, Marc; Hartmann, Felix; Lichter, Peter

A call for accessible tools to unlock single-cell immunometabolism research

NATURE METABOLISM

IF20.8

2024-04-11

OAAI

Cosgrove, Jason; Marcais, Antoine; Hartmann, Felix; Bergthaler, Andreas; Zanoni, Ivan; Corrado, Mauro; Perie, Leila; Cabezas-Wallscheid, Nina; Bousso, Philippe; Alexandrov, Theodore; Kielian, Tammy; Martinez-Martin, Nuria; Opitz, Christiane; Lyssiotis, Costas; Argueello, Rafael; van den Bossche, Jan

Immuno-metabolic dendritic cell vaccine signatures associate with overall survival in vaccinated melanoma patients 免疫代谢树突状细胞疫苗特征与接种疫苗的黑色素瘤患者的总体生存率相关

NATURE COMMUNICATIONS

IF15.7

2023-11-08

OAAI

Adamik, Juraj; Munson, Paul V.; Maurer, Deena M.; Hartmann, Felix J.; Bendall, Sean C.; Arguello, Rafael J.; Butterfield, Lisa H.

Magnitude and kinetics of the human immune cell response associated with severe dengue progression by single-cell proteomics

SCIENCE ADVANCES

IF12.5

2023-03-24

OAAI

Robinson, Makeda L.; Glass, David R.; Duran, Veronica; Rojas, Olga Lucia Agudelo; Sanz, Ana Maria; Consuegra, Monika; Sahoo, Malaya Kumar; Hartmann, Felix J.; Bosse, Marc; Gelvez, Rosa Margarita; Bueno, Nathalia; Pinsky, Benjamin A.; Montoya, Jose G.; Maecker, Holden; Cardenas, Maria Isabel Estupinan; Centeno, Luis Angel Villar; Garrido, Elsa Marina Rojas; Rosso, Fernando; Bendall, Sean C.; Einav, Shirit

Polyunsaturated Fatty Acid-Bound a-Fetoprotein Promotes Immune Suppression by Altering Human Dendritic Cell Metabolism 多不饱和脂肪酸结合的a-胎蛋白通过改变人树突状细胞代谢促进免疫抑制

CANCER RESEARCH

IF16.6

2023-02-27

OAAI

Munson, Paul, V; Adamik, Juraj; Hartmann, Felix J.; Favaro, Patricia M. B.; Ho, Daniel; Bendall, Sean C.; Combes, Alexis J.; Krummel, Matthew F.; Zhang, Karen; Kelley, Robin K.; Butterfield, Lisa H.

Distinct metabolic states guide maturation of inflammatory and tolerogenic dendritic cells 不同的代谢状态指导炎性和致耐受性树突状细胞的成熟

NATURE COMMUNICATIONS

IF15.7

2022-09-02

OAAI

Adamik, Juraj; Munson, Paul, V; Hartmann, Felix J.; Combes, Alexis J.; Pierre, Philippe; Krummel, Matthew F.; Bendall, Sean C.; Arguello, Rafael J.; Butterfield, Lisa H.

Supervised dimensionality reduction for exploration of single-cell data by HSS-LDA

PATTERNS

IF7.4

2022-08-01

OAAI

Amouzgar, Meelad; Glass, David R.; Baskar, Reema; Averbukh, Inna; Kimmey, Samuel C.; Tsai, Albert G.; Hartmann, Felix J.; Bendall, Sean C.

Macrophages are metabolically heterogeneous within the tumor microenvironment

CELL REPORTS

IF6.9

2021-12-01

OAAI

Geeraerts, Xenia; Fernandez-Garcia, Juan; Hartmann, Felix J.; de Goede, Kyra E.; Martens, Liesbet; Elkrim, Yvon; Debraekeleer, Ayla; Stijlemans, Benoit; Vandekeere, Anke; Rinaldi, Gianmarco; De Rycke, Riet; Planque, Melanie; Broekaert, Dorien; Meinster, Elisa; Clappaert, Emile; Bardet, Pauline; Murgaski, Aleksandar; Gysemans, Conny; Nana, Frank Aboubakar; Saeys, Yvan; Bendall, Sean C.; Laoui, Damya; Van den Bossche, Jan; Fendt, Sarah-Maria; Van Ginderachter, Jo A.

研究方向