未登录 A Pan-Cancer Patient-Derived Xenograft Histology Image Repository with Genomic and Pathologic Annotations Enables Deep Learning Analysis White, Brian S.; Woo, Xing Yi; Koc, Soner; Sheridan, Todd; Neuhauser, Steven B.; Wang, Shidan; Evrard, Yvonne A.; Chen, Li; Pour, Ali Foroughi; Landua, John D.; Mashl, R. Jay; Davies, Sherri R.; Fang, Bingliang; Rosa, Maria Gabriela; Evans, Kurt W.; Bailey, Matthew H.; Chen, Yeqing; Xiao, Min; Rubinstein, Jill C.; Sanderson, Brian J.; Lloyd, Michael W.; Domanskyi, Sergii; Dobrolecki, Lacey E.; Fujita, Maihi; Fujimoto, Junya; Xiao, Guanghua; Fields, Ryan C.; Mudd, Jacqueline L.; Xu, Xiaowei; Hollingshead, Melinda G.; Jiwani, Shahanawaz; Acevedo, Saul; Davis-Dusenbery, Brandi N.; Robinson, Peter N.; Moscow, Jeffrey A.; Doroshow, James H.; Mitsiades, Nicholas; Kaochar, Salma; Pan, Chong-xian; Carvajal-Carmona, Luis G.; Welm, Alana L.; Welm, Bryan E.; Govindan, Ramaswamy; Li, Shunqiang; Davies, Michael A.; Roth, Jack A.; Meric-Bernstam, Funda; Xie, Yang; Herlyn, Meenhard; Ding, Li; Lewis, Michael T.; Bult, Carol J.; Dean II, Dennis A.; Chuang, Jeffrey H. 分享 收藏
Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers Mao, Chao; Lei, Guang; Horbath, Amber; Wang, Min; Lu, Zhengze; Yan, Yuelong; Liu, Xiaoguang; Kondiparthi, Lavanya; Chen, Xiong; Cheng, Jun; Li, Qidong; Xu, Zhihao; Zhuang, Li; Fang, Bingliang; Marszalek, Joseph R.; V. Poyurovsky, Masha; Olszewski, Kellen; Gan, Boyi 分享 收藏
Acquired resistance to sotorasib in KRASG12C mutant NSCLC is vulnerable to PI3KmTOR pathway inhibition and regulated by 4E-BP1 Meraz, Ismail M.; Wu, Shuhong; Majidi, Mourad; Ren, Chenghui; Xu, Yi; Meng, Feng; Gao, Lihui; Song, Renduo; Zhang, Ran; Fang, Bingliang; Wang, Qi; Xi, Yuanxin; Wang, Jing; Jung, Sung Yun; Roth, Jack A. 分享 收藏
3-Phosphoinositide-dependent kinase 1 drives acquired resistance to osimertinib (vol 6, 509, 2023) Meraz, Ismail M.; Majidi, Mourad; Fang, Bingliang; Meng, Feng; Gao, Lihui; Shao, RuPing; Song, Renduo; Li, Feng; Lissanu, Yonathan; Chen, Huiqin; Ha, Min Jin; Wang, Qi; Wang, Jing; Shpall, Elizabeth; Jung, Sung Yun; Haderk, Franziska; Gui, Philippe; Riess, Jonathan Wesley; Olivas, Victor; Bivona, Trever G.; Roth, Jack A. 分享 收藏
3-Phosphoinositide-dependent kinase 1 drives acquired resistance to osimertinib Meraz, Ismail M.; Majidi, Mourad; Fang, Bingliang; Meng, Feng; Gao, Lihui; Shao, RuPing; Song, Renduo; Li, Feng; Lissanu, Yonathan; Chen, Huiqin; Ha, Min Jin; Wang, Qi; Wang, Jing; Shpall, Elizabeth; Jung, Sung Yun; Haderk, Franziska; Gui, Philippe; Riess, Jonathan Wesley; Olivas, Victor; Bivona, Trever G.; Roth, Jack A. 分享 收藏
A pan-cancer PDX histology image repository with genomic and pathological annotations for deep learning analysis White, Brian S.; Woo, Xing Yi; Koc, Soner; Sheridan, Todd; Neuhauser, Steven B.; Wang, Shidan; Evrard, Yvonne A.; Landua, John David; Mashl, R. Jay; Davies, Sherri R.; Fang, Bingliang; Raso, Maria Gabriela; Evans, Kurt W.; Bailey, Matthew H.; Chen, Yeqing; Xiao, Min; Rubinstein, Jill; Pour, Ali Foroughi; Dobrolecki, Lacey Elizabeth; Fujita, Maihi; Fujimoto, Junya; Xiao, Guanghua; Fields, Ryan C.; Mudd, Jacqueline L.; Xu, Xiaowei; Hollingshead, Melinda G.; Jiwani, Shahanawaz; Consortium, Pdxnet; Wallace, Tiffany A.; Moscow, Jeffrey A.; Doroshow, James H.; Mitsiades, Nicholas; Kaochar, Salma; Pan, Chong-Xian; Chen, Moon S.; Carvajal-Carmona, Luis G.; Welm, Alana L.; Welm, Bryan E.; Govindan, Ramaswamy; Li, Shunqiang; Davies, Michael A.; Roth, Jack A.; Meric-Bernstam, Funda; Xie, Yang; Herlyn, Meenhard; Ding, Li; Lewis, Michael T.; Bolt, Carol J.; Dean, Dennis A.; Chuang, Jeffrey H. 分享 收藏
WNT5A-RHOA Signaling Is a Driver of Tumorigenesis and Represents a Therapeutically Actionable Vulnerability in Small Cell Lung Cancer Kim, Kee-Beom; Kim, Dong-Wook; Kim, Youngchul; Tang, Jun; Kirk, Nicole; Gan, Yongyu; Kim, Bongjun; Fang, Bingliang; Park, Jae-ll; Zheng, Yi; Park, Kwon-Sik 分享 收藏
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Epstein Barr virus-positive B-cell lymphoma is highly vulnerable to MDM2 inhibitors in vivo Zhang, Xiaoshan; Zhang, Ran; Ren, Chenghui; Xu, Yi; Wu, Shuhong; Meng, Carrie; Pataer, Apar; Song, Xingzhi; Zhang, Jianhua; Yao, Yixin; He, Hua; Chen, Huiqin; Ma, Wencai; Wang, Jing; Meric-Bernstam, Funda; Champlin, Richard E.; Heymach, John, V; Rooney, Cliona M.; Swisher, Stephen G.; Vaporciyan, Ara A.; Roth, Jack A.; You, M. James; Wang, Michael; Fang, Bingliang 分享 收藏
Combined MEK/MDM2 inhibition demonstrates antitumor efficacy in TP53 wild-type thyroid and colorectal cancers with MAPK alterations Pairawan, Seyed; Akcakanat, Argun; Kopetz, Scott; Tapia, Coya; Zheng, Xiaofeng; Chen, Huiqin; Ha, Min Jin; Rizvi, Yasmeen; Holla, Vijaykumar; Wang, Jing; Evans, Kurt W.; Zhao, Ming; Busaidy, Naifa; Fang, Bingliang; Roth, Jack A.; Dumbrava, Ecaterina Ileana; Meric-Bernstam, Funda 分享 收藏
PAF remodels the DREAM complex to bypass cell quiescence and promote lung tumorigenesis Kim, Moon Jong; Cervantes, Christopher; Jung, Youn-Sang; Zhang, Xiaoshan; Zhang, Jie; Lee, Sung Ho; Jun, Sohee; Litovchick, Larisa; Wang, Wenqi; Chen, Junjie; Fang, Bingliang; Park, Jae-Il 分享 收藏
mTORC1 couples cyst(e)ine availability with GPX4 protein synthesis and ferroptosis regulation mTORC1将囊肿 (e) 蛋白的可用性与GPX4蛋白合成和铁死亡调节相结合 Zhang, Yilei; Swanda, Robert, V; Nie, Litong; Liu, Xiaoguang; Wang, Chao; Lee, Hyemin; Lei, Guang; Mao, Chao; Koppula, Pranavi; Cheng, Weijie; Zhang, Jie; Xiao, Zhenna; Zhuang, Li; Fang, Bingliang; Chen, Junjie; Qian, Shu-Bing; Gan, Boyi 分享 收藏
A Novel CDK2/9 Inhibitor CYC065 Causes Anaphase Catastrophe and Represses Proliferation, Tumorigenesis, and Metastasis in Aneuploid Cancers Kawakami, Masanori; Mustachio, Lisa Maria; Chen, Yulong; Chen, Zibo; Liu, Xiuxia; Wei, Cheng-Hsin; Roszik, Jason; Kittai, Adam S.; Danilov, Alexey, V; Zhang, Xiaoshan; Fang, Bingliang; Wang, Jing; Heymach, John, V; Tyutyunyk-Massey, Liliya; Freemantle, Sarah J.; Kurie, Jonathan M.; Liu, Xi; Dmitrovsky, Ethan 分享 收藏
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts (vol 53, pg 86, 2021) 在患者来源的癌症异种移植物的植入和传代过程中保留拷贝数谱 (第53卷，第86页，2021页) Woo, Xing Yi; Giordano, Jessica; Srivastava, Anuj; Zhao, Zi-Ming; Lloyd, Michael W.; de Bruijn, Roebi; Suh, Yun-Suhk; Patidar, Rajesh; Chen, Li; Scherer, Sandra; Bailey, Matthew H.; Yang, Chieh-Hsiang; Cortes-Sanchez, Emilio; Xi, Yuanxin; Wang, Jing; Wickramasinghe, Jayamanna; Kossenkov, Andrew V.; Rebecca, Vito W.; Sun, Hua; Mashl, R. Jay; Davies, Sherri R.; Jeon, Ryan; Frech, Christian; Randjelovic, Jelena; Rosains, Jacqueline; Galimi, Francesco; Bertotti, Andrea; Lafferty, Adam; O'Farrell, Alice C.; Modave, Elodie; Lambrechts, Diether; ter Brugge, Petra; Serra, Violeta; Marangoni, Elisabetta; El Botty, Rania; Kim, Hyunsoo; Kim, Jong-Il; Yang, Han-Kwang; Lee, Charles; Dean, Dennis A., II; Davis-Dusenbery, Brandi; Evrard, Yvonne A.; Doroshow, James H.; Welm, Alana L.; Welm, Bryan E.; Lewis, Michael T.; Fang, Bingliang; Roth, Jack A.; Meric-Bernstam, Funda; Herlyn, Meenhard; Davies, Michael A.; Ding, Li; Li, Shunqiang; Govindan, Ramaswamy; Isella, Claudio; Moscow, Jeffrey A.; Trusolino, Livio; Byrne, Annette T.; Jonkers, Jos; Bult, Carol J.; Medico, Enzo; Chuang, Jeffrey H. 分享 收藏
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts 在患者来源的癌症异种移植物的植入和传代过程中保留拷贝数谱 Woo, Xing Yi; Giordano, Jessica; Srivastava, Anuj; Zhao, Zi-Ming; Lloyd, Michael W.; de Bruijn, Roebi; Suh, Yun-Suhk; Patidar, Rajesh; Chen, Li; Scherer, Sandra; Bailey, Matthew H.; Yang, Chieh-Hsiang; Cortes-Sanchez, Emilio; Xi, Yuanxin; Wang, Jing; Wickramasinghe, Jayamanna; Kossenkov, Andrew V.; Rebecca, Vito W.; Sun, Hua; Mashl, R. Jay; Davies, Sherri R.; Jeon, Ryan; Frech, Christian; Randjelovic, Jelena; Rosains, Jacqueline; Galimi, Francesco; Bertotti, Andrea; Lafferty, Adam; O'Farrell, Alice C.; Modave, Elodie; Lambrechts, Diether; ter Brugge, Petra; Serra, Violeta; Marangoni, Elisabetta; El Botty, Rania; Kim, Hyunsoo; Kim, Jong-Il; Yang, Han-Kwang; Lee, Charles; Dean, Dennis A., II; Davis-Dusenbery, Brandi; Evrard, Yvonne A.; Doroshow, James H.; Welm, Alana L.; Welm, Bryan E.; Lewis, Michael T.; Fang, Bingliang; Roth, Jack A.; Meric-Bernstam, Funda; Herlyn, Meenhard; Davies, Michael A.; Ding, Li; Li, Shunqiang; Govindan, Ramaswamy; Isella, Claudio; Moscow, Jeffrey A.; Trusolino, Livio; Byrne, Annette T.; Jonkers, Jos; Bult, Carol J.; Medico, Enzo; Chuang, Jeffrey H. 分享 收藏
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Novel targeted combination therapies active in KRAS mutant non-small cell lung cancer (NSCLC) identified using patient-derived xenografts (PDX) Zhang, Xiaoshan; Zhang, Ran; Chen, Huiqin; Wang, Li; Ren, Chenghui; Wu, Shuhong; Ha, Min Jin; Morris, Jeffrey; Xi, Yuanxin; Wang, Jing; Gibbons, Don L.; Heymach, John, V; Meric-Bernstam, Funda; Minna, John; Swisher, Stephen G.; Roth, Jack A.; Fang, Bingliang 分享 收藏
Absence of mouse-specific tumor evolution in patient-derived cancer xenografts Giordano, Jessica; Woo, Xing Yi; Srivastava, Anuj; Zhao, Zi-Ming; Lloyd, Michael W.; de Bruijn, Roebi; Suh, Yun-Suhk; Galimi, Francesco; Bertotti, Andrea; Lafferty, Adam; O'Farrell, Alice C.; Modave, Elodie; Lambrechts, Diether; ter Brugge, Petra; Serra, Violeta; Marangoni, Elisabetta; El Botty, Rania; Kim, Jong-Il; Yang, Han-Kwang; Lee, Charles; Dean, Dennis A.; Davis-Dusenbery, Brandi; Evrard, Yvonne A.; Doroshow, James H.; Welm, Alana L.; Welm, Bryan E.; Lewis, Michael T.; Fang, Bingliang; Roth, Jack; Meric-Bernstam, Funda; Herlyn, Meenhard; Davies, Michael; Ding, Li; Li, Shunqiang; Govindan, Ramaswamy; Moscow, Jeffrey A.; Bult, Carol J.; Isella, Claudio; Trusolino, Livio; Byrne, Annette T.; Jonkers, Jos; Chuang, Jeffrey H.; Medico, Enzo 分享 收藏
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