George N. Pavlakis - Publications, H-index & Citations

George N. Pavlakis

National Cancer Institute

79H指数

382论文数

2.2W被引数

收录论文 131

发表时间

Correlates of HIV-1 control after combination immunotherapy HIV-1控制与联合免疫治疗的相关因素

Nature

IF48.5

2025-12-01

PREAI

M. J. Peluso; D. A. Sandel; A. N. Deitchman; S. J. Kim; T. Dalhuisen; H. P. Tummala; R. Tibúrcio; L. Zemelko; G. M. Borgo; S. S. Singh; K. Schwartz; M. Deswal; M. C. Williams; R. Hoh; M. Shimoda; S. Narpala; L. Serebryannyy; M. Khalili; E. Vendrame; D. SenGupta; L. S. Whitmore; J. Tisoncik-Go; M. Gale; R. A. Koup; J. I. Mullins; B. K. Felber; G. N. Pavlakis; J. D. Reeves; C. J. Petropoulos; D. V. Glidden; M. H. Spitzer; L. Gama; M. Caskey; M. C. Nussenzweig; K. W. Chew; T. J. Henrich; S. A. Yukl; L. B. Cohn; S. G. Deeks; R. L. Rutishauser

Highly immunogenic DNA/LION nanocarrier vaccine potently activates lymph nodes inducing long-lasting immunity in macaques 高度免疫原性的DNA/LION纳米载体疫苗能强力激活淋巴结，诱导猕猴产生长效免疫。

ISCIENCE

IF4.1

2025-04-01

OAAI

Karaliota, Sevasti; Moussa, Maha; Rosati, Margherita; Devasundaram, Santhi; Sengupta, Soumya; Goldfarbmuren, Katherine C.; Burns, Robert; Bear, Jenifer; Stellas, Dimitris; Urban, Elizabeth A.; Deleage, Claire; Khandhar, Amit P.; Erasmus, Jesse; Berglund, Peter; Reed, Steven G.; Pavlakis, George N.; Felber, Barbara K.

Leveraging long-acting IL-15 agonists for intratumoral delivery and enhanced antimetastatic activity

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-11-04

OAAI

Hangasky, John A.; Fernandez, Rocio del Valle; Stellas, Dimitris; Hails, Guillermo; Karaliota, Sevasti; Ashley, Gary W.; Felber, Barbara K.; Pavlakis, George N.; Santi, Daniel V.

Focusing HIV-1 Gag T cell responses to highly conserved regions by DNA vaccination in HVTN 119

JCI INSIGHT

IF6.1

2024-08-01

OAAI

Kalams, Spyros A.; Felber, Barbara K.; Mullins, James I.; Scott, Hyman M.; Allen, Mary A.; De Rosa, Stephen C.; Heptinstall, Jack; Tomaras, Georgia D.; Hu, Jiani; DeCamp, Allan C.; Rosati, Margherita; Bear, Jenifer; Pensiero, Michael N.; Eldridge, John; Egan, Michael A.; Hannaman, Drew; McElrath, M. Juliana; Pavlakis, George N.

hetIL-15 and Fenofibrate combination alters the metabolic fitness of tumor-infiltrating CD8+T cells leading to TNBC tumor eradication in mice

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Stellas, Dimitris; Karaliota, Sevasti; Stravokefalou, Vasiliki; Goldfarbmuren, Katherine C.; Myers, Breana; Pavlakis, George N.; Felber, Barbara K.

The immunogenicity of an HIV-1 Gag conserved element DNA vaccine in people with HIV and receiving antiretroviral therapy

AIDS

IF3.1

2023-12-01

OAAI

Jacobson, Jeffrey M.; Felber, Barbara K.; Chen, Huichao; Pavlakis, George N.; Mullins, James I.; De Rosa, Stephen C.; Kuritzkes, Daniel R.; Tomaras, Georgia D.; Kinslow, Jennifer; Bao, Yajing; Olefsky, Maxine; Rosati, Margherita; Bear, Jenifer; Heptinstall, Jack R.; Zhang, Lu; Sawant, Sheetal; Hannaman, Drew; Laird, Gregory M.; Cyktor, Joshua C.; Heath, Sonya L.; Collier, Ann C.; Koletar, Susan L.; Taiwo, Babafemi O.; Tebas, Pablo; Wohl, David A.; Belaunzaran-Zamudio, Pablo F.; McElrath, M. Juliana; Landay, Alan L.

Rapid transient and longer-lasting innate cytokine changes associated with adaptive immunity after repeated SARS-CoV-2 BNT162b2 mRNA vaccinations

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-11-27

OAAI

Rosati, Margherita; Terpos, Evangelos; Homan, Philip; Bergamaschi, Cristina; Karaliota, Sevasti; Ntanasis-Stathopoulos, Ioannis; Devasundaram, Santhi; Bear, Jenifer; Burns, Robert; Bagratuni, Tina; Trougakos, Ioannis P.; Dimopoulos, Meletios A.; Pavlakis, George N.; Felber, Barbara K.

First-in-human phase I/Ib study of NIZ985, a recombinant heterodimer of IL-15 and IL-15Rα, as a single agent and in combination with spartalizumab in patients with advanced and metastatic solid tumors

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2023-10-31

OAAI

Leidner, Rom; Conlon, Kevin; Mcneel, Douglas G.; Wang-Gillam, Andrea; Gupta, Sumati; Wesolowski, Robert; Chaudhari, Monica; Hassounah, Nadia; Lee, Jong Bong; Lee, Lang Ho; O'Keeffe, Jessica A.; Lewis, Nancy; Pavlakis, George N.; Thompson, John A.

Efficient ex vivo expansion of conserved element vaccine-specific CD8+T-cells from SHIV-infected, ART-suppressed nonhuman primates

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-05-03

OAAI

Dross, Sandra; Venkataraman, Rasika; Patel, Shabnum; Huang, Meei-Li; Bollard, Catherine M.; Rosati, Margherita; Pavlakis, George N.; Felber, Barbara K.; Bar, Katharine J.; Shaw, George M.; Jerome, Keith R.; Mullins, James I.; Kiem, Hans-Peter; Fuller, Deborah Heydenburg; Peterson, Christopher W.

Tumor eradication by hetIL-15 locoregional therapy correlates with an induced intratumoral CD103intCD11b+dendritic cell population

CELL REPORTS

IF6.9

2023-05-01

OAAI

Stellas, Dimitris; Karaliota, Sevasti; Stravokefalou, Vasiliki; Angel, Matthew; Nagy, Bethany A.; Goldfarbmuren, Katherine C.; Bergamaschi, Cristina; Felber, Barbara K.; Pavlakis, George N.

Heterodimeric IL-15 (hetIL-15) immunotherapy synergizes with Fatty Acid Metabolism Modulator (FAMM) to eradicate TNBC EO771 murine tumors

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Karaliota, Sevasti; Stellas, Dimitris; Stravokefalou, Vasiliki; Myers, Breana; Felber, Barbara K.; Pavlakis, George N.

Kinetic and molecular analysis of nuclear export factor CRM1 association with its cargo in vivo

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Daelemans, D; Costes, SV; Lockett, S; Pavlakis, GN

XBB.1.5 neutralizing antibodies upon bivalent COVID-19 vaccination are similar to XBB but lower than BQ.1.1

AMERICAN JOURNAL OF HEMATOLOGY

IF9.9

2023-03-07

OAAI

Devasundaram, Santhi; Terpos, Evangelos; Rosati, Margherita; Ntanasis-Stathopoulos, Ioannis; Bear, Jenifer; Burns, Robert; Skourti, Stamatia; Malandrakis, Panagiotis; Trougakos, Ioannis P.; Dimopoulos, Meletios-Athanasios; Pavlakis, George N.; Felber, Barbara K.

Heterodimeric IL-15 (hetIL-15) reduces circulating tumor cells and metastasis formation improving chemotherapy and surgery in 4T1 mouse model of TNBC

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-01-13

OAAI

Stravokefalou, Vasiliki; Stellas, Dimitris; Karaliota, Sevasti; Nagy, Bethany A.; Valentin, Antonio; Bergamaschi, Cristina; Dimas, Konstantinos; Pavlakis, George N.

Delineating the SARS-CoV-2 Induced Interplay between the Host Immune System and the DNA Damage Response Network

VACCINES

IF3.4

2022-10-20

OAAI

Papanikolaou, Christina; Rapti, Vasiliki; Stellas, Dimitris; Stefanou, Dimitra T.; Syrigos, Konstantinos; Pavlakis, George N.; Souliotis, Vassilis L.

Comparative immunogenicity of an mRNA/LNP and a DNA vaccine targeting HIV gag conserved elements in macaques 猕猴中针对HIV gag保守元件的mRNA/LNP和DNA疫苗的比较免疫原性

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-07-22

OAAI

Valentin, Antonio; Bergamaschi, Cristina; Rosati, Margherita; Angel, Matthew; Burns, Robert; Agarwal, Mahesh; Gergen, Janina; Petsch, Benjamin; Oostvogels, Lidia; Loeliger, Edde; Chew, Kara W.; Deeks, Steven G.; Mullins, James I.; Pavlakis, George N.; Felber, Barbara K.

Reduced Antibodies and Innate Cytokine Changes in SARS-CoV-2 BNT162b2 mRNA Vaccinated Transplant Patients With Hematological Malignancies

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-05-25

OAAI

Bergamaschi, Cristina; Pagoni, Maria; Rosati, Margherita; Angel, Matthew; Tzannou, Ifigeneia; Vlachou, Margarita; Darmani, Ismini; Ullah, Amirah; Bear, Jenifer; Devasundaram, Santhi; Burns, Robert; Baltadakis, Ioannis; Gigantes, Stavros; Dimopoulos, Meletios-Athanasios; Pavlakis, George N.; Terpos, Evangelos; Felber, Barbara K.

Sequential Analysis of Binding and Neutralizing Antibody in COVID-19 Convalescent Patients at 14 Months After SARS-CoV-2 Infection

FRONTIERS IN IMMUNOLOGY

IF5.9

2021-11-26

OAAI

Rosati, Margherita; Terpos, Evangelos; Ntanasis-Stathopoulos, Ioannis; Agarwal, Mahesh; Bear, Jenifer; Burns, Robert; Hu, Xintao; Korompoki, Eleni; Donohue, Duncan; Venzon, David J.; Dimopoulos, Meletios-Athanasios; Pavlakis, George N.; Felber, Barbara K.

Distinct neutralization profile of spike variants by antibodies induced upon SARS-CoV-2 infection or vaccination

AMERICAN JOURNAL OF HEMATOLOGY

IF9.9

2021-11-05

OAAI

Rosati, Margherita; Terpos, Evangelos; Agarwal, Mahesh; Karalis, Vangelis; Bear, Jenifer; Burns, Robert; Hu, Xintao; Papademetriou, Demetrios; Ntanasis-Stathopoulos, Ioannis; Trougakos, Ioannis P.; Dimopoulos, Meletios-Athanasios; Pavlakis, George N.; Felber, Barbara K.

Control of SARS-CoV-2 infection after Spike DNA or Spike DNA plus Protein co-immunization in rhesus macaques

PLOS PATHOGENS

IF4.9

2021-09-22

OAAI

Rosati, Margherita; Agarwal, Mahesh; Hu, Xintao; Devasundaram, Santhi; Stellas, Dimitris; Chowdhury, Bhabadeb; Bear, Jenifer; Burns, Robert; Donohue, Duncan; Pessaint, Laurent; Andersen, Hanne; Lewis, Mark G.; Terpos, Evangelos; Dimopoulos, Meletios Athanasios; Wlodawer, Alexander; Mullins, James I.; Venzon, David J.; Pavlakis, George N.; Felber, Barbara K.

研究方向