Hendrik G. Stunnenberg - Publications, H-index & Citations

Hendrik G. Stunnenberg

princess maxima center

115H指数

470论文数

5.5W被引数

收录论文 186

发表时间

De novo H3.3K27M-altered diffuse midline glioma in human brainstem organoids to dissect GD2 CAR T cell function 从头H3.3K27M-人类脑干类器官中改变的弥漫性中线胶质瘤，以解剖GD2 CAR T细胞功能

Nature Cancer

IF28.5

2026-01-05

OAAI

Nils Bessler; Amber K. L. Wezenaar; Hendrikus C. R. Ariese; Celina Honhoff; Noëlle Dommann; Ellen J. Wehrens; Cristian Ruiz Moreno; Thijs J. M. van den Broek; Raphaël V. U. Collot; Daan J. Kloosterman; Farid Keramati; Mieke Roosen; Sam de Blank; Esmée van Vliet; Mario Barrera Román; Lucrezia C. D. E. Gatti; Ali Ertürk; Jürgen Kuball; Zsolt Sebestyén; Marcel Kool; Sara Patrizi; Evelina Miele; Annette Künkele; Mariëtte E. G. Kranendonk; Annelisa M. Cornel; Stefan Nierkens; Christian Mayer; Hendrik G. Stunnenberg; Anna Alemany; Maria Alieva; Anne C. Rios

Modeling Pediatric DMG in Human BrOs (Brainstem-regionalized Organoids) Dissects Tumour-Microglia-Immune Crosstalk and CAR T Cell Dysfunction 在人类脑干区域性类器官（Human BrOs）中模拟儿童弥漫性中脑胶质瘤（Pediatric DMG），解析了肿瘤-小胶质细胞-免疫互作以及CAR T细胞功能障碍。

NEURO-ONCOLOGY

IF13.4

2025-11-01

OAAI

Bessler, Nils; Wezenaar, Amber K. L.; Ariese, Hendrikus C. R.; Honhoff, Celina; Wehrens, Ellen J.; Dommann, Noelle; Moreno, Cristian Ruiz; Van Den Broek, Thijs; Collot, Raphael V. U.; Kloosterman, Daan J.; Keramati, Farid; Roosen, Mieke; De Blank, Sam; Van Vliet, Esmee; Roman, Mario Barrera; Gatti, Lucrezia C. D. E.; Erturk, Ali; Kuball, Jurgen; Sebestyen, Zsolt; Kool, Marcel; Patrizi, Sara; Miele, Evelina; Kunkele, Annette; Kranendonk, Mariette E. G.; Cornel, Annelisa M.; Nierkens, Stefan; Mayer, Christian; Stunnenberg, Hendrik G.; Alemany, Anna; Alieva, Maria; Rios, Anne C.

METTL16-mediated inhibition of MXD4 promotes leukemia through activation of the MYC-MAX axis Mettl16介导的MXD4抑制通过激活MYC-MAX轴促进白血病

Oncogene

IF7.3

2025-09-14

OAAI

Guglielmo Bove; Mehrad Babaei; Alberto Bueno-Costa; Sajid Amin; Nicla Simonelli; Rosaria Benedetti; Carmela Dell’Aversana; Mariarosaria Conte; Liliana Montella; Vincenzo Summa; Margherita Brindisi; Maria Rosaria Del Sorbo; Marco Crepaldi; Gregorio Favale; Nuria Profitos-Peleja; Vincenzo Carafa; Gaël Roué; Fortunato Ciardiello; Annalisa Capuano; Hendrik G. Stunnenberg; Wouter L. Megchelenbrink; Angela Nebbioso; Manel Esteller; Lucia Altucci; Nunzio Del Gaudio

Single-cell multi-omics characterize colorectal tumors, adjacent healthy tissue and matched (tumor) organoids identifying CRC-unique features 单细胞多组学分析表征了结直肠肿瘤、相邻健康组织及匹配的（肿瘤）类器官，并识别了CRC（结直肠癌）特有的特征。

International Journal of Cancer

IF4.7

2025-08-23

OAAI

Zhijun Yu; Merel Derksen; Brigit M. te Pas; Sabrina Ladstätter; Rene Overmeer; Peter Brazda; Marc van de Wetering; Farzin Pourfarzad; Robert G. J. Vries; Wout Megchelenbrink; Christoph Bock; Lucia Altucci; Hendrik G. Stunnenberg

Charting the single-cell and spatial landscape of IDH-wild-type glioblastoma with GBmap 用GBmap绘制IDH野生型胶质母细胞瘤的单细胞和空间景观图

NEURO-ONCOLOGY

IF13.4

2025-05-01

OAAI

Ruiz-Moreno, Cristian; Salas, Sergio Marco; Samuelsson, Erik; Minaeva, Mariia; Ibarra, Ignacio; Grillo, Marco; Brandner, Sebastian; Roy, Ananya; Forsberg-Nilsson, Karin; Kranendonk, Mariette E. G.; Theis, Fabian J.; Nilsson, Mats; Stunnenberg, Hendrik G.

Systemic inflammation impairs myelopoiesis and interferon type I responses in humans 系统性炎症损害人类髓系细胞生成和I型干扰素反应

NATURE IMMUNOLOGY

IF27.6

2025-04-18

OAAI

Keramati, Farid; Leijte, Guus P.; Bruse, Niklas; Grondman, Inge; Habibi, Ehsan; Ruiz-Moreno, Cristian; Megchelenbrink, Wout; Peters van Ton, Annemieke M.; Heesakkers, Hidde; Bremmers, Manita E.; van Grinsven, Erinke; Tesselaar, Kiki; van Staveren, Selma; van der Velden, Walter J.; Preijers, Frank W.; te Pas, Brigit; van de Loop, Raoul; Gerretsen, Jelle; Netea, Mihai G.; Stunnenberg, Hendrik G.; Pickkers, Peter; Kox, Matthijs

Mapping T cell dynamics to molecular profiles through behavior-guided transcriptomics 通过行为引导转录组学将T细胞动态映射到分子谱中

NATURE PROTOCOLS

IF16

2025-02-10

PREAI

Wezenaar, A. K. L.; Pandey, U.; Keramati, F.; Hernandez-Roca, M.; Brazda, P.; Roman, M. Barrera; Cleven, A.; Karaiskaki, F.; Aarts-Riemens, T.; de Blank, S.; Hernandez-Lopez, P.; Heijhuurs, S.; Alemany, A.; Kuball, J.; Sebestyen, Z.; Dekkers, J. F.; Stunnenberg, H. G.; Alieva, M.

DIFFUSE MIDLINE GLIOMAS HIJACK MYELOID CELL POPULATIONS TO INITIATE AN ANTI-INFLAMMATORY TUMOR IMMUNE MICROENVIRONMENT

NEURO-ONCOLOGY

IF13.4

2024-06-18

OAAI

Metselaar, Dennis Serge; du Chatinier, Aimee; Verbaan, Annemieke; Gamas-Vis, Susanne; Waranecki, Piotr; Ruiz-Moreno, Cristian; Kranendonk, Mariette; Stunnenberg, Hendrik; Phoenix, Timothy; Hoving, Eelco Wieger; Kool, Marcel; Meel, Michael Hananja; Hulleman, Esther

Antiviral responses induced by Tdap-IPV vaccination are associated with persistent humoral immunity to Bordetella pertussis

NATURE COMMUNICATIONS

IF15.7

2024-03-08

OAAI

Gillard, Joshua; Suffiotti, Madeleine; Brazda, Peter; Venkatasubramanian, Prashanna B.; Versteegen, Pauline; de Jonge, Marien I.; Kelly, Dominic; Bibi, Sagida; Pinto, Marta Valente; Simonetti, Elles; Babiceanu, Mihaela; Kettring, Andrew; Teodosio, Cristina; de Groot, Ronald; Berbers, Guy; Stunnenberg, Hendrik G.; Schanen, Brian; Fenwick, Craig; Huynen, Martijn A.; Diavatopoulos, Dimitri A.

Dual targeting of cancer metabolome and stress antigens affects transcriptomic heterogeneity and efficacy of engineered T cells 癌症代谢组和应激抗原的双重靶向影响工程化T细胞的转录组异质性和功效

NATURE IMMUNOLOGY

IF27.6

2023-11-27

PREAI

Hernandez-Lopez, Patricia; van Diest, Eline; Brazda, Peter; Heijhuurs, Sabine; Meringa, Angelo; van Heyningen, Lauren Hoorens; Riillo, Caterina; Schwenzel, Caroline; Zintchenko, Marina; Johanna, Inez; Nicolasen, Mara J. T.; Cleven, Astrid; Kluiver, Thomas A.; Millen, Rosemary; Zheng, Jiali; Karaiskaki, Froso; Straetemans, Trudy; Clevers, Hans; de Bree, Remco; Stunnenberg, Hendrik G.; Peng, Weng Chuan; Roodhart, Jeanine; Minguet, Susana; Sebestyen, Zsolt; Beringer, Dennis X.; Kuball, Jurgen

INDUCTION AND TARGETING OF DIFFUSE MIDLINE GLIOMA IN A NOVEL HUMAN PONTINE ORGANOID MODEL

NEURO-ONCOLOGY

IF13.4

2023-09-08

OAAI

Bessler, N.; Moreno, C. Ruiz; Wezenaar, A.; Dommann, N.; Keramati, F.; Ariese, H. C. R.; Honhoff, C.; de Blank, S.; Roman, M. Barrera; Alieva, M.; Wehrens, E. J.; Alemany, A.; Stunnenberg, H. G.; Rios, A. C.

Spic regulates one-carbon metabolism and histone methylation in ground-state pluripotency

SCIENCE ADVANCES

IF12.5

2023-08-18

OAAI

Azad, Fatemeh Mirzadeh; Struys, Eduard A.; Wingert, Victoria; Hannibal, Luciana; Mills, Ken; Jansen, Joop H.; Longley, Daniel B.; Stunnenberg, Hendrik G.; Atlasi, Yaser

Peroxisome proliferator-activated receptor subtype- and cell-type-specific activation of genomic target genes upon adenoviral transgene delivery

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Nielsen, Ronni; Grontved, Lars; Stunnenberg, Hendrik G.; Mandrup, Susanne

Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells 结直肠癌细胞中TCF7L2/TCF4染色质占据的全基因组模式

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

237

OAAI

Hatzis, Pantelis; van der Flier, Laurens G.; van Driel, Marc A.; Guryev, Victor; Nielsen, Fiona; Denissov, Sergei; Nijman, Isaac J.; Koster, Jan; Santo, Evan E.; Welboren, Willem; Versteeg, Rogier; Cuppen, Edwin; van de Wetering, Marc; Clevers, Hans; Stunnenberg, Hendrik G.

In vitro targeting reveals intrinsic histone tail specificity of the Sin3/histone deacetylase and N-CoR/SMRT corepressor complexes

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Vermeulen, M; Carrozza, MJ; Lasonder, E; Workman, JL; Logie, C; Stunnenberg, HG

A feed-forward repression mechanism anchors the Sin3/histone deacetylase and N-CoR/SMRT corepressors on chromatin 前馈抑制机制将Sin3/组蛋白脱乙酰基酶和n-cor/SMRT共抑制剂锚定在染色质上

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Vermeulen, Michiel; Walter, Wendy; Le Guezennec, Xavier; Kim, Jaehoon; Edayathumangalam, Rajeswari S.; Lasonder, Edwin; Luger, Karolin; Roeder, Robert G.; Logie, Colin; Berger, Shelley L.; Stunnenberg, Hendrik G.

Uncleaved TFIIA is a substrate for taspase 1 and active in transcription

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Zhou, HQ; Spicuglia, S; Hsieh, JJD; Mitsiou, DJ; Hoiby, T; Veenstra, GJC; Korsmeyer, SJ; Stunnenberg, HG

MBD2/NuRD and MBD3/NuRD, two distinct complexes with different biochemical and functional properties

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

331

OAAI

Le Guezennec, X; Vermeulen, M; Brinkman, AB; Hoeijmakers, WAM; Cohen, A; Lasonder, E; Stunnenberg, HG

Genome-Wide Profiling of Liver X Receptor, Retinoid X Receptor, and Peroxisome Proliferator-Activated Receptor α in Mouse Liver Reveals Extensive Sharing of Binding Sites 小鼠肝脏中肝X受体，类维生素a X受体和过氧化物酶体增殖物激活受体 α 的全基因组谱分析揭示了结合位点的广泛共享

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

218

OAAI

Boergesen, Michael; Pedersen, Thomas Askov; Gross, Barbara; van Heeringen, Simon J.; Hagenbeek, Dik; Bindesboll, Christian; Caron, Sandrine; Lalloyer, Fanny; Steffensen, Knut R.; Nebb, Hilde I.; Gustafsson, Jan-Ake; Stunnenberg, Hendrik G.; Staels, Bart; Mandrup, Susanne

Single cell transcriptomic analysis of the immune cell compartment in the human small intestine and in Celiac disease

NATURE COMMUNICATIONS

IF15.7

2022-08-22

OAAI

Atlasy, Nader; Bujko, Anna; Baekkevold, Espen S.; Brazda, Peter; Janssen-Megens, Eva; Lundin, Knut E. A.; Jahnsen, Jorgen; Jahnsen, Frode L.; Stunnenberg, Hendrik G.

研究方向