Systemic rewiring of dendritic cells by melanoma-secreted midkine impairs immune surveillance and response to immune checkpoint blockade黑色素瘤分泌的中期因子对树突状细胞进行系统性重构,损害了免疫监视并对免疫检查点阻断的反应产生抑制。NATURE CANCERIF28.52025-03-280PRE
Midkine rewires the melanoma microenvironment toward a tolerogenic and immune-resistant stateNATURE MEDICINEIF502020-10-1972PREAI