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F

Federico Abascal

Wellcome Sanger Institute
H指数:45
被引数:1.4万

个人简介

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教育背景

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工作经历

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荣誉奖项

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Extensive and differential platinum chemotherapy mutagenesis in livers of children

儿童肝脏中广泛且差异化的铂类化疗诱变作用

Science
IF45.8
2026-09-100
PRE
Anna Wenger; Jean-Baptiste Vannier; Henry Lee-Six; Robin Loesch; Giulia Emanuelli; Manas Dave; Mehdi Layeghifard; Andrew R. J. Lawson; Federico Abascal; Pantelis A. Nicola; Taryn D. Treger; Toochi Ogbonnah; Conor Parks; Thomas R. W. Oliver; Jonathan Kennedy; Angus Hodder; Nathaniel D. Anderson; Felipe Luz Torres Silva; Mi K. Trinh; Thomas Dowe; Marwo Habarwaa; James J. Sun; Sergio Assia-Zamora; Miriam Cortes-Cerisuelo; Wayel Jassem; Charlotte Town; Anil Dhawan; Vandana Jain; Karin Straathof; Maesha Deheragoda; Iñigo Martincorena; Liina Palm; J. Ciaran Hutchinson; Tim H. H. Coorens; Claire Trayers; Mariia Yuneva; Nigel Heaton; Adam Shlien; Yoh Zen; Foad J. Rouhani; Sam Behjati
Polyclonal selection of immune checkpoint mutations in thyroid autoimmunity

甲状腺自身免疫中免疫检查点突变的抗体制备性选择

Nature
IF48.5
2026-04-140
OA
Pantelis A. Nicola; Andrew R. J. Lawson; Alexandra Tidd; Juliette Imbert; Yoshihiro Ishida; Luke A. Wylie; Paul A. Scott; Kenny Roberts; Luke M. R. Harvey; Stefanie V. Lensing; Wei Cheng; Federico Abascal; Daniel Leongamornlert; Yvette Hooks; Matthew Mayho; Nicole Müller-Sienerth; Sara Widaa; Laura Mincarelli; James Illing; Flavia Peci; Bee Ling Ng; Georgeina L. Jarman; Andrew J. C. Russell; Krishnaa T. A. Mahbubani; Kourosh Saeb-Parsy; Anna L. Paterson; Krishna Chatterjee; Raheleh Rahbari; Omer Ali Bayraktar; Michael R. Stratton; Peter J. Campbell; John A. Tadross; Nadia Schoenmakers; Iñigo Martincorena
Tissue-specific mutagenesis from endogenous guanine damage is suppressed by Polκ and DNA repair

内源性鸟嘌呤损伤导致的组织特异性突变被Polκ和DNA修复所抑制。

Nature Communications
IF15.7
2025-12-120
OA
Yang Jiang; Moritz Przybilla; Linda Bakker; Foster C. Jacobs; Dylan Mckeon; Roxanne van der Sluijs; Koichi Sato; Juliëtte Wezenbeek; Joeri van Strien; Jeroen Willems; Alexander E. E. Verkennis; Jamie Barnett; Adrian Baez Ortega; Federico Abascal; Peter W. Villalta; Puck Knipscheer; Inigo Martincorena; Silvia Balbo; Juan Garaycoechea
Somatic mutation and selection at population scale

体细胞突变与群体规模选择

Nature
IF48.5
2025-10-080
OAAI
Andrew R. J. Lawson; Federico Abascal; Pantelis A. Nicola; Stefanie V. Lensing; Amy L. Roberts; Georgios Kalantzis; Adrian Baez-Ortega; Natalia Brzozowska; Julia S. El-Sayed Moustafa; Dovile Vaitkute; Belma Jakupovic; Ayrun Nessa; Samuel Wadge; Marc F. Österdahl; Anna L. Paterson; Doris M. Rassl; Raul E. Alcantara; Laura O’Neill; Sara Widaa; Siobhan Austin-Guest; Matthew D. C. Neville; Moritz J. Przybilla; Wei Cheng; Maria Morra; Lucy Sykes; Matthew Mayho; Nicole Müller-Sienerth; Nicholas Williams; Diana Alexander; Luke M. R. Harvey; Thomas Clarke; Alex Byrne; Jamie R. Blundell; Matthew D. Young; Krishnaa T. A. Mahbubani; Kourosh Saeb-Parsy; Hilary C. Martin; Michael R. Stratton; Peter J. Campbell; Raheleh Rahbari; Kerrin S. Small; Iñigo Martincorena
Sperm sequencing reveals extensive positive selection in the male germline

精子测序揭示雄性生殖细胞中存在广泛的正向选择。

Nature
IF48.5
2025-10-080
OAAI
Matthew D. C. Neville; Andrew R. J. Lawson; Rashesh Sanghvi; Federico Abascal; My H. Pham; Alex Cagan; Pantelis A. Nicola; Tetyana Bayzetinova; Adrian Baez-Ortega; Kirsty Roberts; Stefanie V. Lensing; Sara Widaa; Raul E. Alcantara; María Paz García; Sam Wadge; Michael R. Stratton; Peter J. Campbell; Kerrin Small; Iñigo Martincorena; Matthew E. Hurles; Raheleh Rahbari
Saturation genome editing of DDX3X clarifies pathogenicity of germline and somatic variation
NATURE COMMUNICATIONS
IF15.7
2023-12-0610
OAAI
Radford, Elizabeth J.; Tan, Hong-Kee; Andersson, Malin H. L.; Stephenson, James D.; Gardner, Eugene J.; Ironfield, Holly; Waters, Andrew J.; Gitterman, Daniel; Lindsay, Sarah; Abascal, Federico; Martincorena, Inigo; Kolesnik-Taylor, Anna; Ng-Cordell, Elise; Firth, Helen V.; Baker, Kate; Perry, John R. B.; Adams, David J.; Gerety, Sebastian S.; Hurles, Matthew E.
Cross-species oncogenomics offers insight into human muscle-invasive bladder cancer
GENOME BIOLOGY
IF9.4
2023-08-285
OAAI
Wong, Kim; Abascal, Federico; Ludwig, Latasha; Aupperle-Lellbach, Heike; Grassinger, Julia; Wright, Colin W.; Allison, Simon J.; Pinder, Emma; Phillips, Roger M.; Romero, Laura P.; Gal, Arnon; Roady, Patrick J.; Pires, Isabel; Guscetti, Franco; Munday, John S.; Peleteiro, Maria C.; Pinto, Carlos A.; Carvalho, Tania; Cota, Joao; Du Plessis, Elizabeth C.; Constantino-Casas, Fernando; Plog, Stephanie; Moe, Lars; de Brot, Simone; Bemelmans, Ingrid; Amorim, Renee Laufer; Georgy, Smitha R.; Prada, Justina; del Pozo, Jorge; Heimann, Marianne; Nunes, Louisiane de Carvalho; Simola, Outi; Pazzi, Paolo; Steyl, Johan; Ubukata, Rodrigo; Vajdovich, Peter; Priestnall, Simon L.; Suarez-Bonnet, Alejandro; Roperto, Franco; Millanta, Francesca; Palmieri, Chiara; Ortiz, Ana L.; Barros, Claudio S. L.; Gava, Aldo; Soderstrom, Minna E.; O'Donnell, Marie; Klopfleisch, Robert; Manrique-Rincon, Andrea; Martincorena, Inigo; Ferreira, Ingrid; Arends, Mark J.; Wood, Geoffrey A.; Adams, David J.; van der Weyden, Louise
Molecular Evolution of Classic Hodgkin Lymphoma Revealed Through Whole-Genome Sequencing of Hodgkin and Reed Cells
BLOOD CANCER DISCOVERY
IF11.5
2023-01-3118
OA
Maura, Francesco; Ziccheddu, Bachisio; Xiang, Jenny Z.; Bhinder, Bhavneet; Rosiene, Joel; Abascal, Federico; Maclachlan, Kylee H.; Eng, Kenneth Wha; Uppal, Manik; He, Feng; Zhang, Wei; Gao, Qi; Yellapantula, Venkata D.; Trujillo-Alonso, Vicenta; Park, Sunita I.; Oberley, Matthew J.; Ruckdeschel, Elizabeth; Lim, Megan S.; Wertheim, Gerald B.; Barth, Matthew J.; Horton, Terzah M.; Derkach, Andriy; Kovach, Alexandra E.; Forlenza, Christopher J.; Zhang, Yanming; Landgren, Ola; Moskowitz, Craig H.; Cesarman, Ethel; Imielinski, Marcin; Elemento, Olivier; Roshal, Mikhail; Giulino-Roth, Lisa
The architecture of clonal expansions in morphologically normal tissue from cancerous and non-cancerous prostates
MOLECULAR CANCER
IF33.9
2022-09-228
OAAI
Buhigas, Claudia; Warren, Anne Y.; Leung, Wing-Kit; Whitaker, Hayley C.; Luxton, Hayley J.; Hawkins, Steve; Kay, Jonathan; Butler, Adam; Xu, Yaobo; Woodcock, Dan J.; Merson, Sue; Frame, Fiona M.; Sahli, Atef; Abascal, Federico; Martincorena, Inigo; Bova, G. Steven; Foster, Christopher S.; Campbell, Peter; Maitland, Norman J.; Neal, David E.; Massie, Charlie E.; Lynch, Andy G.; Eeles, Rosalind A.; Cooper, Colin S.; Wedge, David C.; Brewer, Daniel S.
Inherited MUTYH mutations cause elevated somatic mutation rates and distinctive mutational signatures in normal human cells
NATURE COMMUNICATIONS
IF15.7
2022-07-0828
OAAI
Robinson, Philip S.; Thomas, Laura E.; Abascal, Federico; Jung, Hyunchul; Harvey, Luke M. R.; West, Hannah D.; Olafsson, Sigurgeir; Lee, Bernard C. H.; Coorens, Tim H. H.; Lee-Six, Henry; Butlin, Laura; Lander, Nicola; Truscott, Rebekah; Sanders, Mathijs A.; Lensing, Stefanie, V; Buczacki, Simon J. A.; Ten Hoopen, Rogier; Coleman, Nicholas; Brunton-Sim, Roxanne; Rushbrook, Simon; Saeb-Parsy, Kourosh; Lalloo, Fiona; Campbell, Peter J.; Martincorena, Inigo; Sampson, Julian R.; Stratton, Michael R.
The longitudinal dynamics and natural history of clonal haematopoiesis
Nature
IF48.5
2022-06-010
OAAI
Margarete A. Fabre; José Guilherme de Almeida; Edoardo Fiorillo; Emily Mitchell; Aristi Damaskou; Justyna Rak; Valeria Orrù; Michele Marongiu; Michael Spencer Chapman; M. S. Vijayabaskar; Joanna Baxter; Claire Hardy; Federico Abascal; Nicholas Williams; Jyoti Nangalia; Iñigo Martincorena; Peter J. Campbell; Eoin F. McKinney; Francesco Cucca; Moritz Gerstung; George S. Vassiliou
Clonal dynamics of haematopoiesis across the human lifespan

人类一生中造血的克隆动力学

Nature
IF48.5
2022-06-010
OAAI
Emily Mitchell; Michael Spencer Chapman; Nicholas Williams; Kevin J. Dawson; Nicole Mende; Emily F. Calderbank; Hyunchul Jung; Thomas Mitchell; Tim H. H. Coorens; David H. Spencer; Heather Machado; Henry Lee-Six; Megan Davies; Daniel Hayler; Margarete A. Fabre; Krishnaa Mahbubani; Federico Abascal; Alex Cagan; George S. Vassiliou; Joanna Baxter; Inigo Martincorena; Michael R. Stratton; David G. Kent; Krishna Chatterjee; Kourosh Saeb Parsy; Anthony R. Green; Jyoti Nangalia; Elisa Laurenti; Peter J. Campbell
Somatic mutation rates scale with lifespan across mammals

哺乳动物的体细胞突变率与寿命成比例

Nature
IF48.5
2022-04-130
OAAI
Alex Cagan; Adrian Baez-Ortega; Natalia Brzozowska; Federico Abascal; Tim H. H. Coorens; Mathijs A. Sanders; Andrew R. J. Lawson; Luke M. R. Harvey; Shriram Bhosle; David Jones; Raul E. Alcantara; Timothy M. Butler; Yvette Hooks; Kirsty Roberts; Elizabeth Anderson; Sharna Lunn; Edmund Flach; Simon Spiro; Inez Januszczak; Ethan Wrigglesworth; Hannah Jenkins; Tilly Dallas; Nic Masters; Matthew W. Perkins; Robert Deaville; Megan Druce; Ruzhica Bogeska; Michael D. Milsom; Björn Neumann; Frank Gorman; Fernando Constantino-Casas; Laura Peachey; Diana Bochynska; Ewan St. John Smith; Moritz Gerstung; Peter J. Campbell; Elizabeth P. Murchison; Michael R. Stratton; Iñigo Martincorena
Increased somatic mutation burdens in normal human cells due to defective DNA polymerases
NATURE GENETICS
IF31.8
2021-09-3081
OAAI
Robinson, Philip S.; Coorens, Tim H. H.; Palles, Claire; Mitchell, Emily; Abascal, Federico; Olafsson, Sigurgeir; Lee, Bernard; Lawson, Andrew R. J.; Lee-Six, Henry; Moore, Luiza; Sanders, Mathijs A.; Hewinson, James; Martin, Lynn; Pinna, Claudia M. A.; Galvotti, Sara; Rahbari, Raheleh; Campbell, Peter J.; Martincorena, Inigo; Tomlinson, Ian; Stratton, Michael R.

研究方向

暂未获取到该数据
I
Iñigo Martincorena
H 指数:84论文数:289被引数:4.7万
P
Peter J. Campbell
H 指数:159论文数:766被引数:13.3万
A
Andrew Lawson
H 指数:21论文数:76被引数:4,518
M
Michael R. Stratton
H 指数:179论文数:655被引数:19.6万
K
Kourosh Saeb‐Parsy
H 指数:67论文数:308被引数:2.7万
M
Michael L. Tress
H 指数:47论文数:111被引数:2.8万
T
Tim Coorens
H 指数:34论文数:151被引数:7,221
K
Krishnaa T. Mahbubani
H 指数:35论文数:149被引数:1.2万
R
Raheleh Rahbari
H 指数:26论文数:91被引数:5,188
M
Moritz Gerstung
H 指数:74论文数:250被引数:4.4万