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E

Enrico Patrucco

University of Torino
H指数:18
被引数:2,081

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FAK inhibitor and RAF/MEK clamp avutometinib enhance KRAS G12C inhibitor efficacy in preclinical models of non–small cell lung cancer

FAK抑制剂和RAF/MEK夹具avutometinib增强KRAS G12C抑制剂在非小细胞肺癌预临床模型中的疗效

Science Translational Medicine
IF14.6
2026-09-300
PRE
Silvia Coma; Monica Musteanu; Cristina Caffarra Malvezzi; Ryan R. Jamieson; Enrico Patrucco; Alessia Mira; Julien Dilly; Ziyue Li; Ana Fernández-Rodríguez; Alejandra López-García; Andrew J. Aguirre; Mariano Barbacid; Chiara Ambrogio; Jonathan A. Pachter
Wiskott-Aldrich syndrome protein (WASP) is a tumor suppressor in T cell lymphoma (vol 25, pg 130, 2019)

Wiskott-Aldrich综合征蛋白（WASP）是T细胞淋巴瘤中的肿瘤抑制因子（卷25，页130，2019）

Nature Medicine
IF50
2026-03-010
PRE
Menotti, Matteo; Ambrogio, Chiara; Cheong, Taek-Chin; Pighi, Chiara; Mota, Ines; Cassel, Seth H.; Compagno, Mara; Wang, Qi; Dall'olio, Riccardo; Minero, Valerio G.; Poggio, Teresa; Sharma, Geeta Geeta; Patrucco, Enrico; Mastini, Cristina; Choudhari, Ramesh; Pich, Achille; Zamo, Alberto; Piva, Roberto; Giliani, Silvia; Mologni, Luca; Collings, Clayton K.; Kadoch, Cigall; Gambacorti-Passerini, Carlo; Notarangelo, Luigi D.; Anton, Ines M.; Voena, Claudia; Chiarle, Roberto
SOS1 inhibitor BI-3406 shows in vivo antitumor activity akin to genetic ablation and synergizes with a KRASG12D inhibitor in KRAS LUAD

SOS1抑制剂BI-3406显示出类似基因敲除的在体抗肿瘤活性，并能与KRASG12D抑制剂协同作用，用于KRAS LUAD。

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2025-03-120
OA
Baltanas, Fernando C.; Kramer-Drauberg, Maximilian; Garcia-Navas, Rosula; Patrucco, Enrico; Petrini, Ettore; Arnhof, Heribert; Olarte-SanJuan, Andrea; Rodriguez-Ramos, Pablo; Borrajo, Javier; Calzada, Nuria; Castellano, Esther; Mair, Barbara; Kostyrko, Kaja; Hofmann, Marco H.
ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer
NATURE CANCER
IF28.5
2023-07-1021
PRE
Mota, Ines; Patrucco, Enrico; Mastini, Cristina; Mahadevan, Navin R.; Thai, Tran C.; Bergaggio, Elisa; Cheong, Taek-Chin; Leonardi, Giulia; Karaca-Atabay, Elif; Campisi, Marco; Poggio, Teresa; Menotti, Matteo; Ambrogio, Chiara; Longo, Dario L.; Klaeger, Susan; Keshishian, Hasmik; Sztupinszki, Zsofia M.; Szallasi, Zoltan; Keskin, Derin B.; Duke-Cohan, Jonathan S.; Reinhold, Bruce; Carr, Steven A.; Wu, Catherine J.; Moynihan, Kelly D.; Irvine, Darrell J.; Barbie, David A.; Reinherz, Ellis L.; Voena, Claudia; Awad, Mark M.; Blasco, Rafael B.; Chiarle, Roberto
Targeting CCR7-PI3K? overcomes resistance to tyrosine kinase inhibitors in ALK-rearranged lymphoma
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2023-06-286
PRE
Mastini, Cristina; Campisi, Marco; Patrucco, Enrico; Mura, Giulia; Ferreira, Antonio; Costa, Carlotta; Ambrogio, Chiara; Germena, Giulia; Martinengo, Cinzia; Peola, Silvia; Mota, Ines; Vissio, Elena; Molinaro, Luca; Arigoni, Maddalena; Olivero, Martina; Calogero, Raffaele; Prokoph, Nina; Tabbo, Fabrizio; Shoji, Brent; Brugieres, Laurence; Geoerger, Birgit; Turner, Suzanne D.; Cuesta-Mateos, Carlos; D'Aliberti, Deborah; Mologni, Luca; Piazza, Rocco; Gambacorti-Passerini, Carlo; Inghirami, Giorgio G.; Chiono, Valeria; Kamm, Roger D.; Hirsch, Emilio; Koch, Raphael; Weinstock, David M.; Aster, Jon C.; Voena, Claudia; Chiarle, Roberto
Genomic Profiling Identifies Putative Pathogenic Alterations in NSCLC Brain Metastases
JTO CLINICAL AND RESEARCH REPORTS
IF3.5
2022-12-013
OA
Nicos, Marcin; Harbers, Luuk; Patrucco, Enrico; Kramer-Drauberg, Maximilian; Zhang, Xiaolu; Voena, Claudia; Kowalczyk, Anna; Bozyk, Aleksandra; Peksa, Rafal; Jarosz, Bozena; Szumilo, Justyna; Simonetti, Michele; Zuk, Monika; Wasag, Bartosz; Reszka, Katarzyna; Duchnowska, Renata; Milanowski, Janusz; Chiarle, Roberto; Bienko, Magda; Krawczyk, Pawel; Jassem, Jacek; Ambrogio, Chiara; Crosetto, Nicola
Comparative Analysis and Isoform-Specific Therapeutic Vulnerabilities of KRAS Mutations in Non-Small Cell Lung Cancer
CLINICAL CANCER RESEARCH
IF10.2
2022-01-2826
OA
Ricciuti, Biagio; Son, Jieun; Okoro, Jeffrey J.; Mira, Alessia; Patrucco, Enrico; Eum, Yoonji; Wang, Xinan; Paranal, Raymond; Wang, Haiyun; Lin, Mika; Haikala, Heidi M.; Li, Jiaqi; Xu, Yue; Alessi, Joao Victor; Chhoeu, Chhayheng; Redig, Amanda J.; Kohler, Jens; Dholakia, Kshiti H.; Chen, Yunhan; Richard, Elodie; Nokin, Marie-Julie; Santamaria, David; Gokhale, Prafulla C.; Awad, Mark M.; Janne, Pasi A.; Ambrogio, Chiara
Frequent mutations of FBXO11 highlight BCL6 as a therapeutic target in Burkitt lymphoma
BLOOD ADVANCES
IF7.1
2021-12-086
OA
Pighi, Chiara; Cheong, Taek-Chin; Compagno, Mara; Patrucco, Enrico; Arigoni, Maddalena; Olivero, Martina; Wang, Qi; Lopez, Cristina; Bernhart, Stephan H.; Grande, Bruno M.; Poggio, Teresa; Langellotto, Fernanda; Bonello, Lisa; Dall'Olio, Riccardo; Martinez-Martin, Sandra; Molinaro, Luca; di Celle, Paola Francia; Whitfield, Jonathan R.; Soucek, Laura; Voena, Claudia; Calogero, Raffaele A.; Morin, Ryan D.; Staudt, Louis M.; Siebert, Reiner; Zamo, Alberto; Chiarle, Roberto
Wiskott-Aldrich syndrome protein (WASP) is a tumor suppressor in T cell lymphoma
NATURE MEDICINE
IF50
2018-12-0357
OAAI
Menotti, Matteo; Ambrogio, Chiara; Cheong, Taek-Chin; Pighi, Chiara; Mota, Ines; Cassel, Seth H.; Compagno, Mara; Wang, Qi; Dall'Olio, Riccardo; Minero, Valerio G.; Poggio, Teresa; Sharma, Geeta Geeta; Patrucco, Enrico; Mastini, Cristina; Choudhari, Ramesh; Pich, Achille; Zamo, Alberto; Piva, Roberto; Giliani, Silvia; Mologni, Luca; Collings, Clayton K.; Kadoch, Cigall; Gambacorti-Passerini, Carlo; Notarangelo, Luigi D.; Anton, Ines M.; Voena, Claudia; Chiarle, Roberto

研究方向

暂未获取到该数据
C
Chiara Ambrogio
H 指数:40论文数:216被引数:5,155
R
Roberto Chiarle
H 指数:56论文数:387被引数:1.1万
C
Claudia Voena
H 指数:37论文数:162被引数:4,625
E
Emilio Hirsch
H 指数:87论文数:560被引数:2.7万
I
Inês Mota
H 指数:16论文数:61被引数:868
C
Cristina Mastini
H 指数:17论文数:85被引数:952
M
Matthias P. Wymann
H 指数:67论文数:211被引数:1.8万
T
Teresa Poggio
H 指数:13论文数:64被引数:840
A
Alessia Mira
H 指数:9论文数:35被引数:557
J
Joseph A. Beavo
H 指数:81论文数:327被引数:2.7万