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Seiya Yamayoshi

University of Tokyo
H指数:43
被引数:9,464

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Structural basis of broad protection against influenza virus by human antibodies targeting the neuraminidase active site via a recurring motif in CDR H3

针对神经氨酸酶活性位点的C3DR H3重复基序的人源抗体对流感病毒广泛保护的构效关系

2025-08-010
OAAI
Targeted protein degraders of SARS-CoV-2 Mpro are more active than enzymatic inhibition alone with activity against nirmatrelvir resistant virus

靶向SARS-CoV-2 Mpro的蛋白质降解剂比单纯的酶抑制作用更有效,且对耐尼玛特雷韦病毒具有活性

2025-04-260
OA
Amino acid substitutions in NSP6 and NSP13 of SARS-CoV-2 contribute to superior virus growth at low temperatures

SARS-CoV-2的NSP6和NSP13中的氨基酸取代有助于在低温下实现出色的病毒生长

2025-02-120
OAAI
An orally available P1′-5-fluorinated Mpro inhibitor blocks SARS-CoV-2 replication without booster and exhibits high genetic barrier
2025-01-070
OAAI
Induction of IGHV3-53 public antibodies with broadly neutralising activity against SARS-CoV-2 including Omicron subvariants in a Delta breakthrough infection case
2024-12-010
PRE