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J

Johannes C. M. Schlachetzki

University of California San Diego
H指数:46
被引数:9,231

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Lysosomal dysfunction drives a transcriptional and epigenetic signature found in disease-associated microglia in neurodegenerative diseases

溶酶体功能障碍驱动神经退行性疾病中疾病相关小胶质细胞的转录和表观遗传特征

Immunity
IF26.3
2026-08-030
PRE
Christopher D. Balak; Johannes C.M. Schlachetzki; Addison J. Lana; Elizabeth West; Christine Hong; Jordan DuGal; Yi Zhou; Benjamin Li; Nathanael J. Spann; Payam Saisan; Vishal Sarsani; Kilian L. Kleemann; Xiaoming Zhang; Martina P. Pasillas; Sydney O’Brien; Juliette A. Bokor; Philip L.S.M. Gordts; Oleg Butovsky; Beth Stevens; Fredrik Kamme
Celebrating neuropathology's contributions to Alzheimer's Disease Research Centers

庆祝神经病理学对阿尔茨海默病研究中心的贡献

Alzheimer's & Dementia
IF11.1
2025-10-140
OAAI
D. Luke Fischer; Lea T. Grinberg; Jared T. Ahrendsen; Thomas G. Beach; Kevin F. Bieniek; Rudolph J. Castellani; Rati Chkheidze; Inma Cobos; Mark Cohen; John F. Crary; Dennis W. Dickson; Brittany N. Dugger; Sara R. Dunlop; Kurt Farrell; Bernardino Ghetti; Mohammad Haeri; William Harrison; Elizabeth Head; Annie Hiniker; Eric J. Huang; Anita Huttner; Pouya Jamshidi; Alifiya Kapasi; C. Dirk Keene; Julia Kofler; Caitlin S. Latimer; Ann C. McKee; Karin Mente; Michael B. Miller; Thomas J. Montine; Meaghan Morris; Melissa E. Murray; Peter T. Nelson; Kathy L. Newell; Richard J. Perrin; Biswarathan Ramani; R. Ross Reichard; Subhojit Roy; Johannes C. M. Schlachetzki; William W. Seeley; Geidy E. Serrano; Salvatore Spina; Andrew F. Teich; Shih-Hsiu J. Wang; Thomas Wisniewski; Edward B. Lee
Dopamine-driven increase in IL-1β in myeloid cells is mediated by differential dopamine receptor expression and exacerbated by HIV

多巴胺驱动的髓系细胞中IL-1β增加是通过差异多巴胺受体表达介导的，并受到HIV的加剧。

JOURNAL OF NEUROINFLAMMATION
IF10.1
2025-03-230
OA
Matt, Stephanie M.; Nolan, Rachel; Manikandan, Samyuktha; Agarwal, Yash; Channer, Breana; Oteju, Oluwatofunmi; Daniali, Marzieh; Canagarajah, Joanna A.; Lupone, Teresa; Mompho, Krisna; Runner, Kaitlyn; Nickoloff-Bybel, Emily; Li, Benjamin; Niu, Meng; Schlachetzki, Johannes C. M.; Fox, Howard S.; Gaskill, Peter J.
NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer's disease progression

NLRP3介导的谷氨酰胺分解调控小胶质细胞吞噬作用以促进阿尔茨海默病进展

IMMUNITY
IF26.3
2025-02-013
PRE
Mcmanus, Roisin M.; Komes, Max P.; Griep, Angelika; Santarelli, Francesco; Schwartz, Stephanie; Perea, Juan Ramon; Schlachetzki, Johannes C. M.; Bouvier, David S.; Khalil, Michelle-Amirah; Lauterbach, Mario A.; Heinemann, Lea; Schlueter, Titus; Pour, Mehran Shaban; Lovotti, Marta; Stahl, Rainer; Duthie, Fraser; Rodriguez-Alcazar, Juan F.; Schmidt, Susanne V.; Spitzer, Jasper; Noori, Peri; Maillo, Alberto; Boettcher, Andreas; Herron, Brian; Mcconville, John; Gomez-Cabrero, David; Tegner, Jesper; Glass, Christopher K.; Hiller, Karsten; Latz, Eicke; Heneka, Michael T.
Direct and indirect regulation of β-glucocerebrosidase by the transcription factors USF2 and ONECUT2

转录因子USF2和ONECUT2对 β-葡糖脑苷脂酶的直接和间接调控

NPJ PARKINSONS DISEASE
IF8.2
2024-10-220
OAAI
Ging, Kathi; Frick, Lukas; Schlachetzki, Johannes; Armani, Andrea; Zhu, Yanping; Gilormini, Pierre-Andre; Dhingra, Ashutosh; Boeck, Desiree; Marques, Ana; Deen, Matthew; Chen, Xi; Serdiuk, Tetiana; Trevisan, Chiara; Sellitto, Stefano; Pisano, Claudio; Glass, Christopher K.; Heutink, Peter; Yin, Jiang-An; Vocadlo, David J.; Aguzzi, Adriano
Genome-wide analyses reveal a potential role for the MAPT, MOBP, and APOE loci in sporadic frontotemporal dementia

全基因组分析揭示了MAPT，MOBP和APOE基因座在散发性额颞叶痴呆中的潜在作用

AMERICAN JOURNAL OF HUMAN GENETICS
IF8.1
2024-07-010
OAAI
Manzoni, Claudia; Kia, Demis A.; Ferrari, Raffaele; Leonenko, Ganna; Costa, Beatrice; Saba, Valentina; Jabbari, Edwin; Tan, Manuela M. X.; Albani, Diego; Alvarez, Victoria; Alvarez, Ignacio; Andreassen, Ole A.; Angiolillo, Antonella; Arighi, Andrea; Baker, Matt; Benussi, Luisa; Bessi, Valentina; Binetti, Giuliano; Blackburn, Daniel J.; Boada, Merce; Boeve, Bradley F.; Borrego-Ecija, Sergi; Borroni, Barbara; Brathen, Geir; Brooks, William S.; Bruni, Amalia C.; Caroppo, Paola; Bandres-Ciga, Sara; Clarimon, Jordi; Colao, Rosanna; Cruchaga, Carlos; Danek, Adrian; de Boer, Sterre C. M.; de Rojas, Itziar; di Costanzo, Alfonso; Dickson, Dennis W.; Diehl-Schmid, Janine; Dobson-Stone, Carol; Dols-Icardo, Oriol; Donizetti, Aldo; Dopper, Elise; Durante, Elisabetta; Ferrari, Camilla; Forloni, Gianluigi; Frangipane, Francesca; Fratiglioni, Laura; Kramberger, Milica G.; Galimberti, Daniela; Gallucci, Maurizio; Garcia-Gonzalez, Pablo; Ghidoni, Roberta; Giaccone, Giorgio; Graff, Caroline; Graff-Radford, Neill R.; Grafman, Jordan; Halliday, Glenda M.; Hernandez, Dena G.; Hjermind, Lena E.; Hodges, John R.; Holloway, Guy; Huey, Edward D.; Illan-Gala, Ignacio; Josephs, Keith A.; Knopman, David S.; Kristiansen, Mark; Kwok, John B.; Leber, Isabelle; Leonard, Hampton L.; Libri, Ilenia; Lleo, Alberto; Mackenzie, Ian R.; Madhan, Gaganjit K.; Maletta, Raffaele; Marquie, Marta; Maver, Ales; Menendez-Gonzalez, Manuel; Milan, Graziella; Miller, Bruce L.; Morris, Christopher M.; Morris, Huw R.; Nacmias, Benedetta; Newton, Judith; Nielsen, Jorgen E.; Nilsson, Christer; Novelli, Valeria; Padovani, Alessandro; Pal, Suvankar; Pasquier, Florence; Pastor, Pau; Perneczky, Robert; Peterlin, Borut; Petersen, Ronald C.; Piguet, Olivier; Pijnenburg, Yolande A. L.; Puca, Annibale A.; Rademakers, Rosa; Rainero, Innocenzo; Reus, Lianne M.; Richardson, Anna M. T.; Riemenschneider, Matthias; Rogaeva, Ekaterina; Rogelj, Boris; Rollinson, Sara; Rosen, Howard; Rossi, Giacomina; Rowe, James B.; Rubino, Elisa; Ruiz, Agustin; Salvi, Erika; Sanchez-Valle, Raquel; Sando, Sigrid Botne; Santillo, Alexander F.; Saxon, Jennifer A.; Schlachetzki, Johannes C. M.; Scholz, Sonja W.; Seelaar, Harro; Seeley, William W.; Serpente, Maria; Sorbi, Sandro; Sordon, Sabrina; St George-Hyslop, Peter; Thompson, Jennifer C.; Van Broeckhoven, Christine; Van Deerlin, Vivianna M.; Van der Lee, Sven J.; Van Swieten, John; Tagliavini, Fabrizio; van der Zee, Julie; Veronesi, Arianna; Vitale, Emilia; Waldo, Maria Landqvist; Yokoyama, Jennifer S.; Nalls, Mike A.; Momeni, Parastoo; Singleton, Andrew B.; Hardy, John; Escott-Price, Valentina
APOE4/4 is linked to damaging lipid droplets in Alzheimer’s disease microglia
Nature
IF48.5
2024-03-130
OAAI
Michael S. Haney; Róbert Pálovics; Christy Nicole Munson; Chris Long; Patrik K. Johansson; Oscar Yip; Wentao Dong; Eshaan Rawat; Elizabeth West; Johannes C. M. Schlachetzki; Andy Tsai; Ian Hunter Guldner; Bhawika S. Lamichhane; Amanda Smith; Nicholas Schaum; Kruti Calcuttawala; Andrew Shin; Yung-Hua Wang; Chengzhong Wang; Nicole Koutsodendris; Geidy E. Serrano; Thomas G. Beach; Eric M. Reiman; Christopher K. Glass; Monther Abu-Remaileh; Annika Enejder; Yadong Huang; Tony Wyss-Coray
RANK ligand converts the NCoR/HDAC3 co-repressor to a PGC1(3-and RNA-dependent co-activator of osteoclast gene expression

RANK配体将NCoR/HDAC3共阻遏物转化为PGC1 (破骨细胞基因表达的3-和RNA依赖性共激活因子

MOLECULAR CELL
IF16.6
2023-10-017
OA
Abe, Yohei; Kofman, Eric R.; Almeida, Maria; Ouyang, Zhengyu; Ponte, Filipa; Mueller, Jasmine R.; Cruz-Becerra, Grisel; Sakai, Mashito; Prohaska, Thomas A.; Spann, Nathanael J.; Resende-Coelho, Ana; Seidman, Jason S.; Stender, Joshua D.; Taylor, Havilah; Fan, Weiwei; Link, Verena M.; Cobo, Isidoro; Schlachetzki, Johannes C. M.; Hamakubo, Takao; Jepsen, Kristen; Sakai, Juro; Downes, Michael; Evans, Ronald M.; Yeo, Gene W.; Kadonaga, James T.; Manolagas, Stavros C.; Rosenfeld, Michael G.; Glass, Christopher K.

研究方向

暂未获取到该数据
C
Christopher K. Glass
H 指数:170论文数:573被引数:13.9万
J
Jürgen Winkler
H 指数:81论文数:531被引数:2.6万
F
Fred H. Gage
H 指数:219论文数:1,079被引数:19.7万
M
Martina P. Pasillas
H 指数:22论文数:42被引数:5,242
X
Xiaoxu Yang
H 指数:33论文数:193被引数:3,044
A
Addison J. Lana
H 指数:9论文数:14被引数:656
R
Ronald J. Ellis
H 指数:87论文数:656被引数:3.0万
Z
Zhengyu Ouyang
H 指数:25论文数:131被引数:3,923
W
William W. Seeley
H 指数:126论文数:673被引数:7.5万
D
Dennis W. Dickson
H 指数:218论文数:2,306被引数:23.0万