Yaeger, Rona; Mezzadra, Riccardo; Sinopoli, Jenna; Bian, Yu; Marasco, Michelangelo; Kaplun, Esther; Gao, Yijun; Zhao, HuiYong; Paula, Arnaud Da Cruz; Zhu, Yingjie; Perez, Almudena Chaves; Chadalavada, Kalyani; Tse, Edison; Chowdhry, Sudhir; Bowker, Sydney; Chang, Qing; Qeriqi, Besnik; Weigelt, Britta; Nanjangud, Gouri J.; Berger, Michael F.; Der-Torossian, Hirak; Anderes, Kenna; Socci, Nicholas D.; Shia, Jinru; Murciano-Goroff, Yonina R.; Li, Bob; Christensen, James G.; Reis-Filho, Jorge S.; Solit, David B.; de Stanchina, Elisa; Lowe, Scott W.; Rosen, Neal; Misale, Sandra

Resistance is futile with fourth-generation EGFR inhibitors

NATURE CANCER

IF28.5

2022-04-148

PRE

Expanding the Reach of Precision Oncology by Drugging All KRAS Mutants

通过给所有KRAS突变体下药来扩大精确肿瘤学的范围

CANCER DISCOVERY

IF33.3

2022-01-19142

OAAI

KRASG12C Mutation Is Associated with Increased Risk of Recurrence in Surgically Resected Lung Adenocarcinoma

CLINICAL CANCER RESEARCH

IF10.2

2021-02-1624

TRK xDFG Mutations Trigger a Sensitivity Switch from Type I to II Kinase Inhibitors

CANCER DISCOVERY

IF33.3

2021-01-0637

OAAI

Cocco, Emiliano; Lee, Ji Eun; Kannan, Srinivasaraghavan; Schram, Alison M.; Won, Helen H.; Shifman, Sophie; Kulick, Amanda; Baldino, Laura; Toska, Eneda; Arruabarrena-Aristorena, Amaia; Kittane, Srushti; Wu, Fan; Cai, Yanyan; Arena, Sabrina; Mussolin, Benedetta; Kannan, Ram; Vasan, Neil; Gorelick, Alexander N.; Berger, Michael F.; Novoplansky, Ofra; Jagadeeshan, Sankar; Liao, Yi; Rix, Uwe; Misale, Sandra; Taylor, Barry S.; Bardelli, Alberto; Hechtman, Jaclyn F.; Hyman, David M.; Elkabets, Moshe; de Stanchina, Elisa; Verma, Chandra S.; Ventura, Andrea; Drilon, Alexander; Scaltriti, Maurizio

EGFR Blockade Reverts Resistance to KRASG12C Inhibition in Colorectal Cancer

EGFR阻断逆转结直肠癌对KRASG12C抑制的耐药性

CANCER DISCOVERY

IF33.3

2020-08-03288

OAAI

Amodio, Vito; Yaeger, Rona; Arcella, Pamela; Cancelliere, Carlotta; Lamba, Simona; Lorenzato, Annalisa; Arena, Sabrina; Montone, Monica; Mussolin, Benedetta; Bian, Yu; Whaley, Adele; Pinnelli, Marika; Murciano-Goroff, Yonina R.; Vakiani, Efsevia; Valeri, Nicola; Liao, Wei-Li; Bhalkikar, Anuja; Thyparambil, Sheeno; Zhao, Hui-Yong; de Stanchina, Elisa; Marsoni, Silvia; Siena, Salvatore; Bertotti, Andrea; Trusolino, Livio; Li, Bob T.; Rosen, Neal; Di Nicolantonio, Federica; Bardelli, Alberto; Misale, Sandra

HER2-Mediated Internalization of Cytotoxic Agents in ERBB2 Amplified or Mutant Lung Cancers

CANCER DISCOVERY

IF33.3

2020-05-01188

OAAI

Li, Bob T.; Michelini, Flavia; Misale, Sandra; Cocco, Emiliano; Baldino, Laura; Cai, Yanyan; Shifman, Sophie; Tu, Hai-Yan; Myers, Mackenzie L.; Xu, Chongrui; Mattar, Marissa; Khodos, Inna; Little, Megan; Qeriqi, Besnik; Weitsman, Gregory; Wilhem, Clare J.; Lalani, Alshad S.; Diala, Irmina; Freedman, Rachel A.; Lin, Nancy U.; Solit, David B.; Berger, Michael F.; Barber, Paul R.; Ng, Tony; Offin, Michael; Isbell, James M.; Jones, David R.; Yu, Helena A.; Thyparambil, Sheeno; Liao, Wei-Li; Bhalkikar, Anuja; Cecchi, Fabiola; Hyman, David M.; Lewis, Jason S.; Buonocore, Darren J.; Ho, Alan L.; Makker, Vicky; Reis-Filho, Jorge S.; Razavi, Pedram; Arcila, Maria E.; Kris, Mark G.; Poirier, John T.; Shen, Ronglai; Tsurutani, Junji; Ulaner, Gary A.; de Stanchina, Elisa; Rosen, Neal; Rudin, Charles M.; Scaltriti, Maurizio

Resistance to TRK inhibition mediated by convergent MAPK pathway activation

NATURE MEDICINE

IF50

2019-08-12156

OAAI

Cocco, Emiliano; Schram, Alison M.; Kulick, Amanda; Misale, Sandra; Won, Helen H.; Yaeger, Rona; Razavi, Pedram; Ptashkin, Ryan; Hechtman, Jaclyn F.; Toska, Eneda; Cownie, James; Somwar, Romel; Shifman, Sophie; Mattar, Marissa; Selcuklu, S. Duygu; Samoila, Aliaksandra; Guzman, Sean; Tuch, Brian B.; Ebata, Kevin; de Stanchina, Elisa; Nagy, Rebecca J.; Lanman, Richard B.; Houck-Loomis, Brian; Patel, Juber A.; Berger, Michael F.; Ladanyi, Marc; Hyman, David M.; Drilon, Alexander; Scaltriti, Maurizio

Sandra Misale

个人简介

教育背景

工作经历

荣誉奖项

研究方向