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Frizzled 7 drives amplification of cancer stem-cell subpopulations and the aggressiveness and poor differentiation of human hepatocellular carcinoma Frizzled 7 促进了癌症干细胞亚群扩增以及人肝细胞癌的侵袭性和分化不良。 Lopez, Anais; Paturel, Alexia; Fares, Nadim; Pez, Floriane; Wang, Guanxiong; Gifu, Patricia; Lefrancois, Lydie; Chouaref, Jihed; Saintigny, Pierre; Selves, Janick; Peron, Jean-Marie; Rivoire, Michel; Merle, Philippe; de Fromentel, Claude Caron 分享 收藏
Strategies for early detection and detailed characterization of oral lesions and head and neck squamous cell carcinoma in Fanconi anemia patients 范可尼贫血患者口腔病变和头颈部鳞状细胞癌的早期检测与详细表征策略 Beddok, Arnaud; Velleuer, Eunike; Fontbrune, Flore Sicre de; Brakenhoff, Ruud H.; Dalle, Jean-Hugues; Dufour, Carlo; Faivre, Sandrine; Genet, Carine; Klijanienko, Jerzy; Krieg, Christine; Leblanc, Thierry; Martinez, Pierre; Latour, Regis Peffault de; Rigolet, Arnaud; Saintigny, Pierre; Lyonnet, Dominique Stoppa; Soulier, Jean; Surralles, Jordi; Schramm, Martin; Thariat, Juliette 分享 收藏
LIBELULE: A Randomized Phase III Study to Evaluate the Clinical Relevance of Early Liquid Biopsy in Patients With Suspicious Metastatic Lung Cancer LIBELULE研究：一项随机III期研究，旨在评估早期液体活检在可疑转移性肺癌患者中的临床相关性。 Swalduz, Aurelie; Schiffler, Camille; Curcio, Hubert; Ambasager, Bana; Le Moel, Gabriel; Debieuvre, Didier; Dot, Jean-Marc; Duruisseaux, Michael; Fournel, Pierre; Odier, Luc; Demolombe, Sylvie; Bizieux-Thaminy, Acya; Peytier, Annie; Schott, Roland; Hominal, Stephane; Tissot, Claire; Bombaron, Pierre; Metzger, Severine; Donnat, Mathilde; Ortiz-Cuaran, Sandra; Rosenfeld, Nitzan; Pipinikas, Christodoulos; Saintigny, Pierre; Perol, Maurice 分享 收藏
Targeting ERK-MYD88 interaction leads to ERK dysregulation and immunogenic cancer cell death Virard, Francois; Giraud, Stephane; Bonnet, Melanie; Magadoux, Lea; Martin, Laetitia; Pham, Thuy Ha; Skafi, Najwa; Deneuve, Sophie; Frem, Rita; Villoutreix, Bruno O.; Sleiman, Nawal Hajj; Reboulet, Jonathan; Merabet, Samir; Chaptal, Vincent; Chaveroux, Cedric; Hussein, Nader; Aznar, Nicolas; Fenouil, Tanguy; Treilleux, Isabelle; Saintigny, Pierre; Ansieau, Stephane; Manie, Serge; Lebecque, Serge; Renno, Toufic; Coste, Isabelle 分享 收藏
Automated reasoning artificial intelligence (AI) to model the cell-cell biochemical and cellular interactions in the tumor microenvironment (TME) of oral cancer (OC) Mahtouk, Karene; Vincent, Maxime; Le Meitour, Yannick; Vanbervliet-Defrance, Beatrice; Canjura, Sonia; Degletagne, Cyril; Tonon, Laurie; Michon, Lucas; Bouaoud, Jebrane; Excoffier, Aude; Zrounba, Philippe; Boutonnet, Remy; Amara, Adam; Saintigny, Pierre 分享 收藏
National multidisciplinary tumor board improves diagnostic stratification and therapeutic management in cancers of unknown primary Dupain, Celia; Jacquin, Nicolas; Guillou, Isabelle; Rouleau, Etienne; Planchon, Julien Masliah; Soubeyran, Isabelle; De La Fouchardiere, Christelle; Tlemsani, Camille; Blons, Helene; Marisa, Laetitia; Patrikidou, Anna; Escande, Fabienne; Blanc, Pierre; Wong, Jennifer; Saintigny, Pierre; Boyault, Sandrine; Buisson, Adrien; Allory, Yves; Vincent-Salomon, Anne; Cockenpot, Vincent; Selves, Janick; Bieche, Ivan; Kamal, Maud; Le Tourneau, Christophe; Watson, Sarah 分享 收藏
Selective translational activation of PBK (PDZ- binding kinase) reveals a molecular vulnerability of drug-tolerant persister cells to targeted therapies in EGFR-mutant lung adenocarcinoma Leonce, Camille; Desage, Anne-Laure; Mourksi, Nour El-Houda; De Souza, Genevieve; Vanbervliet, Beatrice; Charrondiere, Camille; Nicq, Constance; Neri, Jeremy; Swalduz, Aurelie; Tonon, Laurie; Cumunel, Eric; Gadot, Nicolas; Ichim, Gabriel; Diaz, Jean-Jacques; Lovly, Christine; Mazieres, Julien; Tabutin, Mayeul; Perol, Maurice; Lantuejoul, Sylvie; Calvayrac, Olivier; Forest, Fabien; Marcel, Virginie; Saintigny, Pierre; Ortiz-Cuaran, Sandra 分享 收藏
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Survival of bronchopulmonary cancers according to radon exposure Dessemon, Juliette; Perol, Olivia; Chauvel, Cecile; Noelle, Hugo; Coudon, Thomas; Grassot, Leny; Foray, Nicolas; Belladame, Elodie; Fayette, Jerome; Fournie, Francoise; Swalduz, Aurelie; Neidhart, Eve-Marie; Saintigny, Pierre; Tabutin, Mayeul; Boussageon, Maxime; Gomez, Frederic; Avrillon, Virginie; Perol, Maurice; Charbotel, Barbara; Fervers, Beatrice 分享 收藏
GIInger predicts homologous recombination deficiency and patient response to PARPi treatment from shallow genomic profiles Pozzorini, Christian; Andre, Gregoire; Coletta, Tommaso; Buisson, Adrien; Bieler, Jonathan; Ferrer, Loic; Kempfer, Rieke; Saintigny, Pierre; Harle, Alexandre; Vacirca, Davide; Barberis, Massimo; Gilson, Pauline; Roma, Cristin; Saitta, Alexandra; Smith, Ewan; Barras, Floriane Consales; Ripol, Lucia; Fritzsche, Martin; Marques, Ana Claudia; Alkodsi, Amjad; Marin, Ray; Normanno, Nicola; Grimm, Christoph; Mullauer, Leonhard; Harter, Philipp; Pignata, Sandro; Gonzalez-Martin, Antonio; Denison, Ursula; Fujiwara, Keiichi; Vergote, Ignace; Colombo, Nicoletta; Willig, Adrian; Pujade-Lauraine, Eric; Just, Pierre-Alexandre; Ray-Coquard, Isabelle; Xu, Zhenyu 分享 收藏
Spatial Transcriptomics Reveal Pitfalls and Opportunities for the Detection of Rare High-Plasticity Breast Cancer Subtypes Coutant, Angele; Cockenpot, Vincent; Muller, Lauriane; Degletagne, Cyril; Pommier, Roxane; Tonon, Laurie; Ardin, Maude; Michallet, Marie-Cecile; Caux, Christophe; Laurent, Marie; Morel, Anne-Pierre; Saintigny, Pierre; Puisieux, Alain; Ouzounova, Maria; Martinez, Pierre 分享 收藏
National multidisciplinary tumor board improves diagnostic stratification and therapeutic management in cancers of unknown primary Bieche, Ivan; Kamal, Maud; Jacquin, Nicolas; Dupain, Celia; Guillou, Isabelle; Rouleau, Etienne; Masliah-Planchon, Julien; Soubeyran, Isabelle; De La Fouchardiere, Christelle; Tlemsani, Camille; Blons, Helene; Marisa, Laetitia; Patrikidou, Anna; Escande, Fabienne; Blanc, Pierre; Wong, Jennifer; Saintigny, Pierre; Boyault, Sandrine; Buisson, Adrien; Allory, Yves; Vincent-Salomon, Anne; Cockenpot, Vincent; Selves, Janick; Le Tourneau, Christophe; Watson, Sarah 分享 收藏
RSK3 switches cell fate: from stress-induced senescence to malignant progression RSK3改变细胞命运: 从应激诱导的衰老到恶性进展 Huna, Anda; Flaman, Jean-Michel; Lodillinsky, Catalina; Zhu, Kexin; Makulyte, Gabriela; Pakulska, Victoria; Coute, Yohann; Ruisseaux, Clemence; Saintigny, Pierre; Hernandez-Vargas, Hector; Defossez, Pierre-Antoine; Boissan, Mathieu; Martin, Nadine; Bernard, David 分享 收藏
Clinical utility of circulating tumor HPV16 DNA detection in plasma from oropharyngeal squamous cell carcinoma patients de Carvalho, A. C.; Torrens, L.; Chopard, P.; Gaborieau, V.; Cortez, R.; Waterboer, T.; Saintigny, P.; Roux, P. E.; Virani, S.; Brennan, P.; Perdomo, S. 分享 收藏
Identification of biomarkers of survival across multiple cancer types using eXplainable artificial intelligence 使用可解释的人工智能识别多种癌症类型的生存生物标志物 Angileri, F.; Kindermans, M.; Attignon, V. K.; Afshar, M.; Blay, J-Y.; Boulahfa, J.; Boyault, S.; Chabaud, S.; Clave, G.; Garin, G.; Parmentier, F.; Perol, D.; Sohier, E.; Turcat, T.; Tredan, O.; Viari, A.; Saintigny, P. 分享 收藏
Non-small cell lung cancer: Artificial intelligence enables the identification of survival signatures complementary to an Immunologically active gene expression signature involving previous therapies 非小细胞肺癌: 人工智能可以识别与先前治疗相关的免疫活性基因表达特征互补的生存特征 Saintigny, P.; Iriso, P.; Afshar, M.; Attignon, V. K.; Auclair, J.; Boulahfa, J.; Boussageon, M.; Fayette, J.; Foy, J-P.; Karabajakian, A.; Kindermans, M.; Lamkhioued, M.; Lantuejoul, S.; Michon, L.; Ortiz-Cuaran, S.; Parmentier, F.; Perol, M.; Swalduz, A.; Turcat, T. 分享 收藏
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