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L

Lars Mäegdefessel

tum university hospital rechts der isar
H指数:59
被引数:1.1万

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Transient efferocytosis-induced activation of IKKβ reprograms macrophages to promote tissue resolution in mice

瞬时凋亡细胞吞噬诱导的IKKβ激活重编程巨噬细胞以促进小鼠组织修复

Nature Communications
IF15.7
2026-10-260
OAAI
David Ngai; Saheli Chowdhury; Santosh R. Sukka; George Kuriakose; Brian Havens; Mustafa Yalcinkaya; Jeremy M. Frey; Heather Doviak; Jennifer W. Bradford; Bernhard Dorweiler; Hanna Winter; Lars Maegdefessel; Kenneth Walsh; Joshua P. Thaler; Alan R. Tall; Ira Tabas
Artery tertiary lymphoid organs encode a pathogenic high-affinity autoantibody−autoantigen pair in atherosclerosis

动脉三级淋巴组织编码动脉粥样硬化中致病性高亲和力自身抗体-自身抗原对

Nature Cardiovascular Research
IF10.8
2026-09-070
OAAI
Chuankai Zhang; Xi Zhang; Yi Ran; Zhihua Wang; Liping Li; Shu Wang; Junjie Zheng; Yixin Zhang; Ting Sun; Yutao Li; Shu Lu; Mingyang Hong; Zhe Ma; Sabine Steffens; Michael Hristov; Xavier Blanchet; Jingpu Zhu; Xinwen Dou; Xinyi Deng; Klaus Dornmair; Desheng Hu; Shibojyoti Lahiri; Axel Imhof; Nadja Sachs; Lars Maegdefessel; Jingyi Xiao; Jianning Zhang; Yan Wang; Hua Hong; Livia Habenicht; Xinyu Weng; Junbo Ge; Christian Weber; Donato Santovito; Rachael Bashford-Rogers; Sarajo K. Mohanta; Klaus Ley; Andreas J. R. Habenicht; Changjun Yin
Plasma infrared molecular fingerprinting stratifies residual risk in coronary artery disease and reflects clonal haematopoiesis-associated biology

血浆红外分子指纹分析可分层冠状动脉疾病中的残余风险并反映与克隆性造血相关的生物学

European Heart Journal
IF35.6
2026-07-290
OAAI
Moritz von Scheidt; Tarek Eissa; Johannes Krefting; Christian Friess; Marius Schwab; Irina Pugach; Daniel Meyer; Jacqueline Aschauer; Zhifen Chen; Gregor Hoermann; Manja Meggendorfer; Dario Bongiovanni; Daniel Breucker; Karsten Wenger; Felix Voll; Christian Graesser; Thorsten Kessler; Hendrik B Sager; Lilith Oldenbuettel; Martina Dreßen; Stefanie A Doppler; Muamer Kameric; Sabine Seeler; Markus Krane; Lars Maegdefessel; Judith S Hecker; Florian Bassermann; Michaela Sander; Stefan Holdenrieder; Ingo Hilgendorf; Florian Leuschner; Shaunak S Adkar; Clint L Miller; Minna U Kaikkonen; Michal Mokry; Gerard Pasterkamp; Pradeep Natarajan; José J Fuster; Alexander G Bick; J Brett Heimlich; Michael A Rieger; Sebastian Cremer; Stefanie Dimmeler; Andreas M Zeiher; Wesley T Abplanalp; Johan L M Björkegren; Nicholas J Leeper; Birgit Linkohr; Annette Peters; Adnan Kastrati; Salvatore Cassese; Wolfgang Koenig; Frank Fleischmann; Heribert Schunkert; Mihaela Žigman; null
Endothelial cannabinoid CB1 receptor deficiency reduces shear stress-induced arterial inflammation and lipid uptake

内皮大麻素CB1受体缺陷可降低剪切应力诱导的动脉炎症和脂质摄取

Nature Communications
IF15.7
2026-07-070
OAAI
Bingni Chen; Aishvaryaa Prabhu; Guo Li; Anna Kaltenbach; Yong Wang; George Shakir; Lucia Natarelli; Remco Megens; Yvonne Jansen; Srishti Ramanathan; Martina Geiger; Alexander Faussner; Michael Hristov; Daniel Richter; Xinyu Di; Mario van der Stelt; Vasiliki Triantafyllidou; Zhaolong Li; Nadja Sachs; Valentina Paloschi; Lars Maegdefessel; Susanna M. Hofmann; Martina Schifferer; Mikael Simons; Christian Weber; Donato Santovito; Stephan Herzig; Raquel Guillamat Prats; Sabine Steffens
Proteomics reveals spatial and molecular heterogeneities in advanced atherosclerotic carotid artery plaques

蛋白质组学揭示进展期动脉粥样硬化颈动脉斑块的空间和分子异质性

Nature Cardiovascular Research
IF10.8
2026-06-220
OAAI
Ankit Sinha; Nadja Sachs; Elena Kratz; Jessica Pauli; Sophia Steigerwald; Vincent Albrecht; Thierry M. Nordmann; Enes Ugur; Edwin H. Rodriguez; Marie-Luise Engl; Patricia Skowronek; Denys Oliinyk; Andreas Metousis; Moritz von Scheidt; Michael Wierer; Hanna Winter; Heribert Schunkert; Daniela Branzan; Lars Maegdefessel; Matthias Mann
Identification of unannotated microproteins involved in endothelial cell homeostasis, dysfunction and vascular disease

鉴定参与内皮细胞稳态、功能障碍和血管疾病的未注释微小蛋白

Cardiovascular Research
IF13.3
2026-05-190
OAAI
Mauro Siragusa; Johannes Graumann; Carsten Kuenne; Stefan Günther; Sylvia Jeratsch; Beyza Güven; Sebastian Süsser; Sweta Talyan; Bethlehem Bezuneh; Yves Matthess; Matteo Cartura; Xiaozhu Zhou; Haaglim Cho; Nadja Sachs; Lars Maegdefessel; Oliver J Müller; Christian Troidl; Holger M Nef; Mario Looso; Manuel Kaulich; Stefan Offermanns; Ingrid Fleming
Exercise Reverses Mental Stress–Induced Vascular Inflammation and Builds Stress Resilience

运动逆转精神压力诱导的血管炎症并增强压力恢复力

jacc: basic to translational science
IF0
2026-04-220
OAAI
Ulrike Meyer-Lindemann; Karina Borbil; Marius Schwab; Aldo Moggio; Rui Shen; M. Amin Sharifi; Tan An Dang; Viktoria Schories; Raphael Rottenkolber; Svenja Rapelius; Julia Hinterdobler; Carina Mauersberger; Moritz von Scheidt; Lars Maegdefessel; Henning Wackerhage; Karsten Köhler; Egija Berga-Švītiņa; Baiba Vilne; Michael Hristov; Christian Weber
Single cell spatial transcriptomics integration deciphers the morphological heterogeneity of atherosclerotic carotid arteries

单细胞空间转录组学整合解析了动脉粥样硬化性颈动脉的形态异质性

Nature Communications
IF15.7
2025-12-180
OAAI
Jessica Pauli; Daniel Garger; Fatemeh Peymani; Justus Wettich; Nadja Sachs; Johannes Wirth; Katja Steiger; Christina Hillig; Hanrui Zhang; Ira Tabas; Alan Tall; Mingyao Li; Muredach P. Reilly; Daniela Branzan; Holger Prokisch; Michael P. Menden; Lars Maegdefessel
ChemR23 prevents phenotypic switching of vascular smooth muscle cells into macrophage-like foam cells in atherosclerosis

ChemR23可预防动脉粥样硬化中血管平滑肌细胞向巨噬细胞样泡沫细胞的表型转化。

CARDIOVASCULAR RESEARCH
IF13.3
2025-12-010
OAAI
Evans, Bryce R.; Schulz, Julia; Triantafyllidou, Vasiliki; Yerly, Anais; Thakur, Manovriti; Angliker, Nico; Siegrist, Mark; Jansen, Yvonne; Yan, Yi; Maas, Sanne L.; Gold, Christoph; Farina, Floriana M.; Bayer, Batoul; Bartelt, Alexander; Weber, Christian; Wettich, Justus; Maegdefessel, Lars; Sachs, Nadia; Schindewolf, Marc; Kotelis, Drosos; Noels, Heidi; Santovito, Donato; van der Vorst, Emiel P. C.; Doering, Yvonne
Transcription regulation by TBX18 in smooth muscle cells is essential for normal aortic development and homeostasis

TBX18在平滑肌细胞中对转录的调控对于正常主动脉发育和稳态维持至关重要。

CARDIOVASCULAR RESEARCH
IF13.3
2025-11-011
PRE
Mukherjee, Debanjan; Larcher, Veronica; Winter, Hanna; Sachs, Nadja; Andriani, Francesca; Chiesa, Mattia; Perrucci, Gianluca L.; Rega, Sara; Gunther, Stefan; Kuenne, Carsten; Martin, Jody C.; Gu, Yusu; Pelisek, Jaroslav; Fischer, Ariane; Peruzzo, Sofia; Pizzo, Emanuele; Peterson, Kirk L.; Dimmeler, Stefanie; Maegdefessel, Lars; Cattaneo, Paola; Evans, Sylvia M.; Guimaraes-Camboa, Nuno
Integrated single-cell atlas of human atherosclerotic plaques

Traeuble, K.; Munz, M.; Pauli, J.; Sachs, N.; Vafadarnejad, E.; Carrillo-Roa, T.; Maegdefessel, L.; Kastner, P.; Heinig, M. 人类动脉粥样硬化斑块的单细胞整合图谱。Nat. Commun. 2025, 16, 8255. [Google Scholar] [CrossRef] [PubMed]

Nature Communications
IF15.7
2025-09-100
OAAI
Korbinian Traeuble; Matthias Munz; Jessica Pauli; Nadja Sachs; Eshan Vafadarnejad; Tania Carrillo-Roa; Lars Maegdefessel; Peter Kastner; Matthias Heinig
Clonal haematopoiesis of indeterminate potential and mortality in coronary artery disease

克隆性中性粒细胞发育异常潜能与冠状动脉疾病死亡率

EUROPEAN HEART JOURNAL
IF35.6
2025-09-013
OAAI
von Scheidt, Moritz; Adkar, Shaunak S.; Krefting, Johannes; Hoermann, Gregor; Meggendorfer, Manja; Bauer, Sabine; Mitchell, Shaneice; Pugach, Irina; Friess, Christian; Ma, Angela; Hao, Ke; Steigerwald, Sophia; Wahle, Maria; Kessler, Thorsten; Schwab, Marius; Voll, Felix; Mokry, Michal; Sofokleous, Charalampos; Palm, Kaylin C. A.; Bongiovanni, Dario; Fleig, Julia; Oldenbuettel, Lilith; Chen, Zhifen; Hecker, Judith S.; Bassermann, Florian; Maegdefessel, Lars; Graw, Matthias; Ruusalepp, Arno; Hilgendorf, Ingo; Leuschner, Florian; Sager, Hendrik B.; Heimlich, J. Brett; Koenig, Wolfgang; Cremer, Sebastian; Leistner, David M.; Abplanalp, Wesley T.; Dimmeler, Stefanie; Zeiher, Andreas M.; van der Laan, Sander W.; Pasterkamp, Gerard; Braun, Christian; Jaiswal, Siddhartha; Kovacic, Jason C.; Kern, Wolfgang; Haferlach, Claudia; Mann, Matthias; Cassese, Salvatore; Kastrati, Adnan; Haferlach, Torsten; Leeper, Nicholas J.; Bjorkegren, Johan L. M.; Schunkert, Heribert
Abdominal aortic aneurysm histomorphology shows different inflammatory aspects among patients and is not associated with classic risk factors-the HistAAA study

腹主动脉瘤组织形态学显示患者间存在不同的炎症方面，且与经典危险因素无关——HistAAA研究

CARDIOVASCULAR RESEARCH
IF13.3
2025-04-290
PRE
Nackenhorst, Maja Carina; Menges, Felix; Bohmann, Bianca; Zschaepitz, David; Bollwein, Christine; Flemming, Sven; Sachs, Nadja; Eilenberg, Wolf; Brostjan, Christine; Neumayer, Christoph; Trenner, Matthias; Ibing, Wiebke; Schelzig, Hubert; Reeps, Christian; Maegdefessel, Lars; Regele, Heinz; Wagenhaeuser, Markus Udo; Scholz, Claus Jurgen; Gasser, Thomas Christian; Busch, Albert
An atypical atherogenic chemokine that promotes advanced atherosclerosis and hepatic lipogenesis

一种非典型的致动脉粥样硬化趋化因子，可促进晚期动脉粥样硬化和肝脏脂生成

NATURE COMMUNICATIONS
IF15.7
2025-03-070
OA
El Bounkari, Omar; Zan, Chunfang; Yang, Bishan; Ebert, Simon; Wagner, Jonas; Bugar, Elina; Kramer, Naomi; Bourilhon, Priscila; Kontos, Christos; Zarwel, Marlies; Sinitski, Dzmitry; Milic, Jelena; Jansen, Yvonne; Kempf, Wolfgang E.; Sachs, Nadja; Maegdefessel, Lars; Ji, Hao; Gokce, Ozgun; Riols, Fabien; Gerra, Simona; Hoffmann, Adrian; Brandhofer, Markus; Avdic, Maida; Bucala, Richard; Megens, Remco T. A.; Willemsen, Nienke; Messerer, Denise; Schulz, Christian; Bartelt, Alexander; Harm, Tobias; Rath, Dominik; Doering, Yvonne; Gawaz, Meinrad; Kapurniotu, Aphrodite; Bernhagen, Juergen
Clonal Hematopoiesis of Indeterminate Potential Increases Mortality Risk in Coronary Artery Disease

Clonal Hematopoiesis of Indeterminate Potential Increases Mortality Risk in Coronary Artery Disease

CIRCULATION
IF38.6
2024-11-120
PRE
Von Scheidt, Moritz; Adkar, Shaunak; Krefting, Johannes; Hoermann, Gregor; Meggendorfer, Manja; Bauer, Sabine; Pugach, Irina; Friess, Christian; Ma, Angela; Hao, Ke; Steigerwald, Sophia; Kessler, Thorsten; Mokry, Michal; Bongiovanni, Dario; Fleig, Julia; Oldenbuettel, Lilith; Chen, Zhifen; Hecker, Judith S.; Bassermann, Florian; Maegdefessel, Lars; Graw, Matthias; Ruusalepp, Arno; Hilgendorf, Ingo; Leuschner, Florian; Koenig, Wolfgang; Cremer, Sebastian; Leistner, David; Dimmeler, Stefanie; Zeiher, Andreas; Braun, Christian; Mitchell, Shaneice; Jaiswal, Siddhartha; Kovacic, Jason; Mann, Matthias; Kastrati, Adnan; Haferlach, Claudia; Haferlach, Torsten; Leeper, Nick; Bjorkegren, Johan; Schunkert, Heribert

研究方向

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