未登录 Selective decay of interferon mRNAs controls antiviral immunity and innate memory 干扰素mRNA的选择性降解调控抗病毒免疫和固有记忆 Braun, Rachel M.; Ferretti, Max B.; Lee, Jae Seung; Miller, Jesse; Castellana, Lauren; Acuna, Jorge; Whig, Kanupriya; Dohnalova, Lenka; Descamps, Helene C.; Huber, Alex S.; Muramatsu, Hiromi; Hewins, Peter; Li, Yue; Bhutda, Smita; Etwebi, Zienab; Dittmar, Mark; Cook, Thomasina; Schultz, David C.; Blackshear, Perry J.; Jurado, Kellie Ann; Thaiss, Christoph A.; Pardi, Norbert; Lynch, Kristen W.; Cherry, Sara 分享 收藏
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Discovery of Fragment-Based Inhibitors of SARS-CoV-2 PLPro Wei, Qiangqiang; Taylor, Ashley J.; Barmade, Mahesh Angadrao; Teuscher, Kevin B.; Chowdhury, Somanath; Apakama, Chideraa; Anderson-Daniels, Jordan; Yongqing, Zhu; Schultz, David C.; Rietz, Tyson A.; South, Taylor M.; Crow, Mackenzie M.; Zhao, Bin; Amporndanai, Kangsa; Sensintaffar, John L.; Phan, Jason; Cherry, Sara; Denison, Mark; Lee, Taekyu; Fesik, Stephen W. 分享 收藏
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An oral non-covalent non-peptidic inhibitor of SARS-CoV-2 Mpro ameliorates viral replication and pathogenesis in vivo Zhou, Nian E.; Tang, Su; Bian, Xuelin; Parai, Maloy K.; Krieger, Inna V.; Flores, Armando; Jaiswal, Pradeep K.; Bam, Radha; Wood, Jeremy L.; Shi, Zhe; Stevens, Laura J.; Scobey, Trevor; Diefenbacher, Meghan V.; Moreira, Fernando R.; Baric, Thomas J.; Acharya, Arjun; Shin, Joonyoung; Rathi, Manish M.; Wolff, Karen C.; Riva, Laura; Bakowski, Malina A.; Mcnamara, Case W.; Catanzaro, Nicholas J.; Graham, Rachel L.; Schultz, David C.; Cherry, Sara; Kawaoka, Yoshihiro; Halfmann, Peter J.; Baric, Ralph S.; Denison, Mark R.; Sheahan, Timothy P.; Sacchettini, James C. 分享 收藏
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Histone chaperone HIRA, promyelocytic leukemia protein, and p62/SQSTM1 coordinate to regulate inflammation during cell senescence Dasgupta, Nirmalya; Lei, Xue; Shi, Christina Huan; Arnold, Rouven; Teneche, Marcos G.; Miller, Karl N.; Rajesh, Adarsh; Davis, Andrew; Anschau, Valesca; Campos, Alexandre R.; Gilson, Rebecca; Havas, Aaron; Yin, Shanshan; Chua, Zong Ming; Liu, Tianhui; Proulx, Jessica; Alcaraz, Michael; Rather, Mohammed Iqbal; Baeza, Josue; Schultz, David C.; Yip, Kevin Y.; Berger, Shelley L.; Adams, Peter D. 分享 收藏
The lipopeptide Pam3CSK4 inhibits Rift Valley fever virus infection and protects from encephalitis Griesman, Trevor; Mcmillen, Cynthia M.; Negatu, Seble Getenet; Hulahan, Jesse J.; Whig, Kanupriya; Dohnalova, Lenka; Dittmar, Mark; Thaiss, Christoph A.; Jurado, Kellie A.; Schultz, David C.; Hartman, Amy L.; Cherry, Sara 分享 收藏
Inherited C-terminal TREX1 variants disrupt homology-directed repair to cause senescence and DNA damage phenotypes in Drosophila, mice, and humans Chauvin, Samuel D.; Ando, Shoichiro; Holley, Joe A.; Sugie, Atsushi; Zhao, Fang R.; Poddar, Subhajit; Kato, Rei; Miner, Cathrine A.; Nitta, Yohei; Krishnamurthy, Siddharth R.; Saito, Rie; Ning, Yue; Hatano, Yuya; Kitahara, Sho; Koide, Shin; Stinson, W. Alexander; Fu, Jiayuan; Surve, Nehalee; Kumble, Lindsay; Qian, Wei; Polishchuk, Oleksiy; Andhey, Prabhakar S.; Chiang, Cindy; Liu, Guanqun; Colombeau, Ludovic; Rodriguez, Raphael; Manel, Nicolas; Kakita, Akiyoshi; Artyomov, Maxim N.; Schultz, David C.; Coates, P. Toby; Roberson, Elisha D. O.; Belkaid, Yasmine; Greenberg, Roger A.; Cherry, Sara; Gack, Michaela U.; Hardy, Tristan; Onodera, Osamu; Kato, Taisuke; Miner, Jonathan J. 分享 收藏
Bile Acid Metabolism Mediates Cholesterol Homeostasis and Promotes Tumorigenesis in Clear Cell Renal Cell Carcinoma Riscal, Romain; Gardner, Sarah M.; Coffey, Nathan J.; Carens, Madeleine; Mesaros, Clementina; Xu, Jimmy P.; Xue, Yizheng; Davis, Leah; Demczyszyn, Sara; Vogt, Austin; Olia, Adam; Finan, Jennifer M.; Godfrey, Jason; Schultz, David C.; Blair, Ian A.; Keith, Brian; Marmorstein, Ronen; Skuli, Nicolas; Simon, M. Celeste 分享 收藏
TXNRD1 drives the innate immune response in senescent cells with implications for age-associated inflammation Hao, Xue; Zhao, Bo; Towers, Martina; Liao, Liping; Monteiro, Edgar Luzete; Xu, Xin; Freeman, Christina; Peng, Hongzhuang; Tang, Hsin-Yao; Havas, Aaron; Kossenkov, Andrew V.; Berger, Shelley L.; Adams, Peter D.; Speicher, David W.; Schultz, David; Marmorstein, Ronen; Zaret, Kenneth S.; Zhang, Rugang 分享 收藏
The RNA helicase DDX39A binds a conserved structure in chikungunya virus RNA to control infection Tapescu, Iulia; Taschuk, Frances; Pokharel, Swechha M.; Zginnyk, Oleksandr; Ferretti, Max; Bailer, Peter F.; Whig, Kanupryia; Madden, Emily A.; Heise, Mark T.; Schultz, David C.; Cherry, Sara 分享 收藏
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SARS-CoV-2 ORF6 protein does not antagonize interferon signaling in respiratory epithelial Calu-3 cells during infection SARS-CoV-2 ORF6蛋白在感染期间不会拮抗呼吸道上皮Calu-3细胞中的干扰素信号传导 Li, Minghua; Ayyanathan, Kasirajan; Dittmar, Mark; Miller, Jesse; Tapescu, Iulia; Lee, Jae Seung; McGrath, Marisa E.; Xue, Yong; Vashee, Sanjay; Schultz, David C.; Frieman, Matthew B.; Cherry, Sara 分享 收藏
Spurious intragenic transcription is a feature of mammalian cellular senescence and tissue aging Sen, Payel; Donahue, Greg; Li, Catherine; Egervari, Gabor; Yang, Na; Lan, Yemin; Robertson, Neil; Shah, Parisha P.; Kerkhoven, Erik; Schultz, David C.; Adams, Peter D.; Berger, Shelley L. 分享 收藏
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Human UBN1 Is an Ortholog of Yeast Hpc2p and Has an Essential Role in the HIRA/ASF1a Chromatin-Remodeling Pathway in Senescent Cells Banumathy, Gowrishankar; Somaiah, Neeta; Zhang, Rugang; Tang, Yong; Hoffmann, Jason; Andrake, Mark; Ceulemans, Hugo; Schultz, David; Marmorstein, Ronen; Adams, Peter D. 分享 收藏
Human CABIN1 Is a Functional Member of the Human HIRA/UBN1/ASF1a Histone H3.3 Chaperone Complex Rai, Taranjit Singh; Puri, Aastha; McBryan, Tony; Hoffman, Jason; Tang, Yong; Pchelintsev, Nikolay A.; van Tuyn, John; Marmorstein, Ronen; Schultz, David C.; Adams, Peter D. 分享 收藏
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