Lee-Jah Chang

AstraZeneca

H指数:14

被引数:1,964

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Safety, Pharmacokinetics, and Predicted Neutralizing Activity of the SARS-CoV-2 Monoclonal Antibody Sipavibart: Results from Little DIPPER and the SUPERNOVA Substudy

Sipavibart单克隆抗体的安全性、药代动力学及预测的中和活性：Little DIPPER和SUPERNOVA亚组研究的结果

Infectious Diseases and Therapy

IF5.3

2026-09-070

OAAI

Pharmacokinetic Comparability Assessment of Tixagevimab and Cilgavimab Developed for COVID-19 Prevention and Treatment Using Standard Exposure Metrics and Partial Area Under the Curve

基于标准暴露指标和部分曲线下面积评估用于COVID-19预防和治疗的Tixagevimab和Cilgavimab的药代动力学可比性分析

Clinical Pharmacokinetics

IF4

2026-03-310

OAAI

A SARS-CoV-2 variant‑adjusted threshold of protection model for monoclonal antibody pre-exposure prophylaxis against COVID-19

针对COVID-19的单克隆抗体暴露前预防的保护阈值模型（SARS-CoV-2变体调整）

Nature Communications

IF15.7

2025-10-140

OAAI

Efficacy and safety of sipavibart for prevention of COVID-19 in individuals who are immunocompromised (SUPERNOVA): a randomised, controlled, double-blind, phase 3 trial

西帕韦伯特（sipavibart）预防免疫低下人群COVID-19的疗效与安全性（SUPERNOVA）：一项随机、对照、双盲、III期试验

The Lancet Infectious Diseases

IF0

2025-02-010

PRE

Ghady Haidar; Steven Thomas; Paul Loubet; Ross I Baker; Thomas Benfield; Jim Boonyaratanakornkit; Sasisopin Kiertiburanakul; Alfred H J Kim; Erin E Longbrake; Jean-Michel Molina; Roger Paredes; David Tucker; Alison Uriel; Julia Weinmann-Menke; Anastasia A Aksyuk; Lindsay E Clegg; Alexander Currie; Haitao Yang; Karin Flyrin; Michael Gibbs; Manish Shroff; John L Perez; Lee-Jah Chang; Taylor S Cohen; Paul Griffin; Orla Morrissey; Michelle Yong; Michael O'Sullivan; Ross Baker; Robert Scott; Joseph Sasadeusz; Hilde Bollen; Catherine Orban; Cecile Tremblay; Matthew Cheng; Thomas Benfield; Lothar Wiese; Henrik Nielsen; Nina Breinholt Staerke; Isik Johansen; Paul Loubet; Thomas Guimard; Zoha Maakaroun Vermesse; Maeva Lefebvre; Dominique Deplanque; Inès Ben Ghezala; Odile Launay; Jean-Michel Molina; Amandine Gagneux Brunon; Kamar Nassim; Illies Benotmane; Thomas Systchenko; Siegrfried Wassenberg; Andrea Everding; Jakob Malin; Christoph Schindler; Julia Weinmann-Menke; Oliver Witzke; David Tucker; Ruth Payne; Paul Dargan; David Turner; Oliver Koch; Thomas William Rampling; Rachel Protheroe; Ashley Whittington; Alison Uriel; Lawrence Barnes; Richard Fitzgerald; Talha Munir; Gili Regev; Noa Eliakim Raz; Hock Hin Chua; Peng Peng Ang; Adli Ali; Sharifah Faridah Syed Omar; Chieh Lee Wong; Mariusz Korkosz; Michal Kwiatek; Pyoeng Gyun Choe; Eu Suk Kim; Sung-Han Kim; Sung Yong Lee; Louis Yi Ann Chai; Po Ying Chia; Yvonne Fu Zi Chan; Jose María Echave-Sustaeta; Jose Maria Ignacio Garcia; Antonio Manuel Perez Fernandez; Vicente Estrada Perez; Inmaculada Salcedo Leal; Roger Paredes; Francisco Tejerina Picado; Joaquin Lopez-Contreras Gonzalez; Marta Aldea Novo; Victor del Campo Perez; Helena Moza Moriñigo; Xavier Martinez Gomez; José Javier Castrodeza Sanz; Jose Angel Hernandez Rivas; Min-Chi Lu; Feng-Yee Chang; Piroon Mootsikapun; Methee Chayakulkeeree; Sasisopin Kiertiburanakul; Romanee Chaiwarith; Tavitiya Sudjaritruk; Weerawat Manosuthi; James Sullivan; Howard Reinfeld; Paul Pickrell; Faisal Amin; Martha Fanning; Ibrahim Perez; Mark Kutner; James Moy; William Smith; Michael Denenberg; William Hartman; Diego Torres; Manish Jain; David Pham; Marimer Rensoli Velazquez; Jorge Venereo; Michael Thakor; Abel Murillo; Joseph Rose; Thomas Klein; Jodumutt Bhat; Ghady Haidar; Robert Levinson; Edouard Martin; David Wheeler; Mark Vishnepolsky; Giralt Yanez; Christopher Palma; Larry Bush; Anup Patel; Jim Boonyaratanakornkit; Alfred Kim; Apinya Vutikullird; Charles Rose; German Hernandez; Philip Waller; Alexander White; Timothy Colander; Robin Avery; Cameron Wolfe; Arvind Madan; Peale Chuang; William Towner; Rebecca Kumar; Justin Yanuck; Alan Koff; Antony Nguyen Vanbang; Jaswinder Singh; Bindu Balani; Syed Mustafa; George Fadda; Mark Adams; Russell Petrak; Bianca Weinstock-Guttman; Andrew Pippas; Khan Nedd; Jason Raasch; Sona Kamat; Dennis Ross; Michael Jacobs; Bobby Khan; Hiten Upadhyay; Armando Peaz; David Mooney; Sophia Koo; Pedro Ylisastigui; Craig Julien; Mary Bailey; Adam Frome; Jennifer Wang; Khan Nedd; Steven Standaert; Amy Slenker; Belkis Delgado; Erin Longbrake; Sanjiv Anand; Michael Koren; David Weiss; Mayur Ramesh; Alan Kivitz; Moises Huaman; Dimitrios Farmakiotis; Audrey Mahajan; Xian Qiao; Fadi Saba; Yessica Sachdeva; Saleha Sajid; Michael Stephens; Enrique Mendez; Pablo Tebas-Medrano; Amar Majjhoo; Awawu Igbinadolor; Uriel Sandkovsky; Harry Studdard; Robert Noveck; Anita Kohli; Jayant Kumar; Karen Miller; Mousab Tabbaa; Moges Sisay; Mona Amin; Adnan Ahmad; Alexander Dela Llana; Paul Kniery; Charles Fogarty; Atul Singhal; David Lazar; Binh (Quang) Tran; Hanh Chu; Jehad Abdalla; Nawal Al Kaabi

AZD3152 neutralizes SARS-CoV-2 historical and contemporary variants and is protective in hamsters and well tolerated in adults

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2024-06-261

PRE

Cai, Yingyun; Diallo, Seme; Rosenthal, Kim; Ren, Kuishu; Flores, Daniel J.; Dippel, Andrew; Oganesyan, Vaheh; van Dyk, Nydia; Chen, Xiaoru; Cantu, Erin; Choudhary, Rakesh; Sulikowski, Michal; Adissu, Hibret; Chawla, Bhavna; Kar, Swagata; Liu, Chang; Dijokaite-Guraliuc, Aiste; Mongkolsapaya, Juthathip; Rajan, Saravanan; Loo, Yueh-Ming; Beavon, Rohini; Webber, Chris; Chang, Lee-Jah; Thomas, Steven; Clegg, Lindsay; Zhang, Huixia; Screaton, Gavin R.; Philbin, Nora; Harre, Mark; Selim, Abdulhafez; Martinez-Alier, Nuria; Uriel, Alison; Cohen, Taylor S.; Perez, John L.; Esser, Mark T.; Blair, Wade; Francica, Joseph R.

Immunogenicity and safety of high-dose quadrivalent influenza vaccine in Japanese adults ≥65 years of age: a randomized controlled clinical trial

大剂量四价流感疫苗在 ≥ 65岁日本成人中的免疫原性和安全性: 一项随机对照临床试验

HUMAN VACCINES & IMMUNOTHERAPEUTICS

IF3.5

2019-11-1918

OAAI

Sanchez, Leilani; Matsuoka, Osamu; Inoue, Satoshi; Inoue, Takahiro; Meng, Ya; Nakama, Takahiro; Kato, Kumiko; Pandey, Aseem; Chang, Lee-Jah; Ando, Kiyotaka; Ito, Mild; Kawai, Makoto; Kawai, Mie; Miyashita, Yumi; Nakai, Nozomu; Otake, Sachiko; Yamaguchi, Izumi; Daito, Hisayoshi; Kanada, Shigeto; Owada, Yasuko; Takeya, Miyuki; Takeya, Yasushi; Yamamoto, Hiroko; Yamamoto, Koichi; Bonaparte, Kathryn; Boyle, Jacqueline; Broudic, Karine; De Bruijn, Iris; De Sousa, Jennifer; Emori, Toshihiro; Garg, Sanjay; Hayashi, Kaoru; Hollingsworth, Rosalind; Ida, Sanae; Ishii, Yasunori; Janosczyk, Helene; Kawaguchi, Osamu; Khoury, Rawia; Kobayashi, Yuko; Landolfi, Victoria; Marshall, Erik; Matsuzaki, Minako; Menard, Lisa; Miyazawa, Rina; Nishimori, Shoko; Ohshima, Shinobu; Ohtsuki, Miyako; Oka, Hayato; Okada, Keiko; Otsuka, Akiko; Patskan, Viktor; Pekala, David; Quinn, Therese; Ruparel, Renuka; Samson, Sandrine; Shinozaki, Makoto; Sirisuphmitr, Nuchra; Sodeyama, Takashi; Takebuchi, Kazushi; Terashima, Romi; Urso, Maxime; Yoshida, Arika

A Randomized, Double-Blinded, Placebo-Controlled, Phase 1 Study of a Replication-Defective Herpes Simplex Virus (HSV) Type 2 Vaccine, HSV529, in Adults With or Without HSV Infection

JOURNAL OF INFECTIOUS DISEASES

IF4.5

2019-05-0657

OAAI

Protection against malaria at 1 year and immune correlates following PfSPZ vaccination (vol 22, pg 614, 2016)

NATURE MEDICINE

IF50

2016-06-071

PREAI

Ishizuka, Andrew S.; Lyke, Kirsten E.; DeZure, Adam; Berry, Andrea A.; Richie, Thomas L.; Mendoza, Floreliz H.; Enama, Mary E.; Gordon, Ingelise J.; Chang, Lee-Jah; Sarwar, Uzma N.; Zephir, Kathryn L.; Holman, LaSonji A.; James, Eric R.; Billingsley, Peter F.; Gunasekera, Anusha; Chakravarty, Sumana; Manoj, Anita; Li, MingLin; Ruben, Adam J.; Li, Tao; Eappen, Abraham G.; Stafford, Richard E.; Natasha, K. C.; Murshedkar, Tooba; DeCederfelt, Hope; Plummer, Sarah H.; Hendel, Cynthia S.; Novik, Laura; Costner, Pamela J. M.; Saunders, Jamie G.; Laurens, Matthew B.; Plowe, Christopher V.; Flynn, Barbara; Whalen, William R.; Todd, J. P.; Noor, Jay; Rao, Srinivas; Sierra-Davidson, Kailan; Lynn, Geoffrey M.; Epstein, Judith E.; Kemp, Margaret A.; Fahle, Gary A.; Mikolajczak, Sebastian A.; Fishbaugher, Matthew; Sack, Brandon K.; Kappe, Stefan H. I.; Davidson, Silas A.; Garver, Lindsey S.; Bjorkstrom, Niklas K.; Nason, Martha C.; Graham, Barney S.; Roederer, Mario; Sim, B. Kim Lee; Hoffman, Stephen L.; Ledgerwood, Julie E.; Seder, Robert A.

Protection against malaria at 1 year and immune correlates following PfSPZ vaccination

NATURE MEDICINE

IF50

2016-05-09288

PREAI

Safety and tolerability of chikungunya virus-like particle vaccine in healthy adults: a phase 1 dose-escalation trial

LANCET

IF88.5

2014-12-01213

PREAI

Prime-Boost Interval Matters: A Randomized Phase 1 Study to Identify the Minimum Interval Necessary to Observe the H5 DNA Influenza Vaccine Priming Effect

JOURNAL OF INFECTIOUS DISEASES