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Il-mi Okazaki

Tokushima University

H指数:27

被引数:4,977

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Binding of LAG-3 to stable peptide-MHC class II limits T cell function and suppresses autoimmunity and anti-cancer immunity

IF26.3

2022-05-01101

OA

PD-1 agonism by anti-CD80 inhibits T cell activation and alleviates autoimmunity

NATURE IMMUNOLOGY

IF27.6

2022-02-1053

PRE

PD-1 preferentially inhibits the activation of low-affinity T cells

PD-1优先抑制低亲和力T细胞的活化

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-08-2513

OA

LAG-3: from molecular functions to clinical applications

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2020-09-13305

OAAI

PD-1 Imposes Qualitative Control of Cellular Transcriptomes in Response to T Cell Activation

IF16.6

2020-03-0143

OAAI

PD-1 aborts the activation trajectory of autoreactive CD8+ T cells to prohibit their acquisition of effector functions

JOURNAL OF AUTOIMMUNITY

IF7

2019-12-0114

OAAI

Atypical motifs in the cytoplasmic region of the inhibitory immune co-receptor LAG-3 inhibit T cell activation

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2019-04-0175

OAAI

PD-1 Primarily Targets TCR Signal in the Inhibition of Functional T Cell Activation

FRONTIERS IN IMMUNOLOGY

IF5.9

2019-03-29134

OAAI

Restriction of PD-1 function by cis -PD-L1/CD80 interactions is required for optimal T cell responses

PD-1功能的限制 <i>cis</i> -PD-L1/CD80相互作用是最佳T细胞反应所必需的

IF45.8

2019-01-010

PREAI

LAG-3 inhibits the activation of CD4+ T cells that recognize stable pMHCII through its conformation-dependent recognition of pMHCII

LAG-3通过其对pMHCII的构象依赖性识别来抑制识别稳定pMHCII的CD4 T细胞的活化

NATURE IMMUNOLOGY

IF27.6

2018-10-22200

PREAI

Paradoxical development of polymyositis-like autoimmunity through augmented expression of autoimmune regulator (AIRE)

通过增强自身免疫调节因子 (AIRE) 的表达，发生多肌炎样自身免疫的矛盾发展

JOURNAL OF AUTOIMMUNITY

IF7

2018-01-0115

OAAI

TRIM28 prevents autoinflammatory T cell development in vivo

TRIM28可防止体内自身炎性T细胞发育

NATURE IMMUNOLOGY

IF27.6

2012-04-2986

PREAI

Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2011-04-2545

OAAI

PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2011-02-07293

OAAI

AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2009-12-2966

OAAI

Molecular mechanism for generation of antibody memory

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

IF4.7

2008-11-2019

OAAI

A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations

IF7.3

2008-11-1062

OAAI

Organ-specific profiles of genetic changes in cancers caused by activation-induced cytidine deaminase expression

INTERNATIONAL JOURNAL OF CANCER

IF4.7

2008-10-1579

OAAI

Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium

NATURE MEDICINE

IF50

2007-04-01436

OAAI

Activation-induced cytidine deaminase (AID) promotes B cell lymphomagenesis in Emu-cmyc transgenic mice

激活诱导的胞苷脱氨酶 (AID) 促进emu-cmyc转基因小鼠的b细胞淋巴瘤发生

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2007-01-3084

OAAI