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K

Khandan Keyomarsi

university of texas md anderson cancer center
H指数:59
被引数:1.4万

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CDK2 inhibitor BLU-222 synergizes with CDK4/6 inhibitors in drug resistant breast cancers through p21/p27 induction

CDK2抑制剂BLU-222通过p21/p27诱导与CDK4/6抑制剂在耐药性乳腺癌中的协同作用

Nature Communications
IF15.7
2026-01-220
OAAI
Linjie Luo; Yan Wang; Tuyen Bui; Xiaoting Jiang; Mei-Kuang Chen; Xiayu Rao; Sepideh Mohammadhosseinpour; Mi Li; Serena Kim; Rachel Y. Kim; Saba Kamaliasl; Carmen W. Ulizio; Spyros Tsavachidis; Juliana Navarro-Yepes; Nicole M. Kettner; Hannah Wingate; Funda Meric-Bernstam; Kelly K. Hunt; Jing Wang; Kerrie Faia; Khandan Keyomarsi
CDK2 inhibition enhances CDK4/6 inhibitor antitumor activity in comprehensive breast cancer PDX model screen

CDK2抑制增强了CDK4/6抑制剂在综合乳腺癌PDX模型筛选中的抗肿瘤活性

npj Breast Cancer
IF7.6
2025-12-030
OAAI
Nealia C. House; Maxine M. Chen; Sima Khazaei; Victoria Brown; Philip Ramsden; David H. Peng; Sydney Moore; Liang Yuan; Rentian Wu; Fangyang Wang; Linjie Luo; Ningping Feng; Christopher A. Bristow; Timothy A. Yap; Khandan Keyomarsi; Joseph R. Marszalek; Scott Ribich; Mikael L. Rinne; Lakshmi B. Muthuswamy; Kerrie L. Faia
IL-6 predicts CDK4/6 inhibitor resistance, identifying STAT3 as a target in HR + /HER2-negative metastatic breast cancer

IL-6预测CDK4/6抑制剂耐药性，确定STAT3为HR + /HER2阴性转移性乳腺癌的靶点

npj Precision Oncology
IF8
2025-07-250
OAAI
Nicole M. Kettner; Tuyen N. Bui; Juliana Navarro-Yepes; Sanaz Ghotbaldini; Bethanie Quintela; Catherine K. Luo; Nghi Lam; Xiayu Rao; Akshara Singareeka Raghavendra; Yan Wang; Nancy Azizian; T. Kris Eckols; Moses Makokha Kasembeli; Kurt Evans; Min Yi; Hannah Wingate; Jing Wang; Aysegul A. Sahin; Funda Meric-Bernstam; Kelly K. Hunt; Senthil Damodaran; David J. Tweardy; Debu Tripathy; Khandan Keyomarsi
Single-cell RNA sequencing identifies molecular biomarkers predicting late progression to CDK4/6 inhibition in patients with HR+/HER2-metastatic breast cancer

单细胞RNA测序识别预测HR+/HER2-转移性乳腺癌患者对CDK4/6抑制剂的晚期进展的分子生物标志物

MOLECULAR CANCER
IF33.9
2025-02-151
OA
Luo, Linjie; Yang, Peng; Mastoraki, Sofia; Rao, Xiayu; Wang, Yan; Kettner, Nicole M.; Raghavendra, Akshara Singareeka; Tripathy, Debasish; Damodaran, Senthil; Hunt, Kelly K.; Wang, Jing; Li, Ziyi; Keyomarsi, Khandan
STAT3 protects hematopoietic stem cells by preventing activation of a deleterious autocrine type-I interferon response
LEUKEMIA
IF13.4
2024-03-111
OA
Patel, Bhakti; Zhou, Yifan; Babcock, Rachel L.; Ma, Feiyang; Zal, M. Anna; Kumar, Dhiraj; Medik, Yusra B.; Kahn, Laura M.; Pineda, Josue E.; Park, Elizabeth M.; Schneider, Sarah M.; Tang, Ximing; Raso, Maria Gabriela; Jeter, Collene R.; Zal, Tomasz; Clise-Dwyer, Karen; Keyomarsi, Khandan; Giancotti, Filippo G.; Colla, Simona; Watowich, Stephanie S.

研究方向

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K
Kelly K. Hunt
H 指数:130论文数:1,407被引数:6.0万
T
Tuyen Bui
H 指数:20论文数:203被引数:1,705
C
Cansu Karakaş
H 指数:19论文数:191被引数:1,389
S
Saïd Akli
H 指数:25论文数:135被引数:2,270
N
Nicole M. Kettner
H 指数:12论文数:94被引数:1,582
H
Hannah F. Wingate
H 指数:11论文数:58被引数:635
L
Linjie Luo
H 指数:12论文数:51被引数:1,091
D
Debu Tripathy
H 指数:69论文数:1,158被引数:2.5万
闵义 封面图
闵义
H 指数:48论文数:253被引数:7,321
A
Akshara Singareeka Raghavendra
H 指数:21论文数:233被引数:1,593