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收藏Development of an AAV-based model of tauopathy targeting retinal ganglion cells and the mouse visual pathway to study the role of microglia in Tau pathology
Duwat, Charlotte; Leal, Pauline; Vautheny, Audrey; Auregan, Gwennaelle; Josephine, Charlene; Gaillard, Marie-Claude; Herard, Anne-Sophie; Jan, Caroline; Gipchtein, Pauline; Mitja, Julien; Fouquet, Stephane; Niepon, Marie-Laure; Hantraye, Philippe; Brouillet, Emmanuel; Bonvento, Gilles; Cambon, Karine; Bemelmans, Alexis - Pierre
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收藏Altered activity-regulated H3K9 acetylation at TGF-beta signaling genes during egocentric memory in Huntington's disease
Alcala-Vida, Rafael; Lotz, Caroline; Brule, Baptiste; Seguin, Jonathan; Decraene, Charles; Awada, Ali; Bombardier, Aurelie; Cosquer, Brigitte; de Vasconcelos, Anne Pereira; Brouillet, Emmanuel; Cassel, Jean-Christophe; Boutillier, Anne-Laurence; Merienne, Karine
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收藏Reactive astrocytes promote proteostasis in Huntington's disease through the JAK2-STAT3 pathway
Abjean, Laurene; Ben Haim, Lucile; Riquelme-Perez, Miriam; Gipchtein, Pauline; Derbois, Celine; Palomares, Marie-Ange; Petit, Fanny; Herard, Anne-Sophie; Gaillard, Marie-Claude; Guillermier, Martine; Gaudin-Guerif, Mylene; Auregan, Gwennaelle; Sagar, Nisrine; Hery, Cameron; Dufour, Noelle; Robil, Noemie; Kabani, Mehdi; Melki, Ronald; De la Grange, Pierre; Bemelmans, Alexis P.; Bonvento, Gilles; Deleuze, Jean-Francois; Hantraye, Philippe; Flament, Julien; Bonnet, Eric; Brohard, Solene; Olaso, Robert; Brouillet, Emmanuel; Carrillo-de Sauvage, CoMaria-Angeles; Escartin, Carole
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收藏THY-Tau22 mouse model accumulates more tauopathy at late stage of the disease in response to microglia deactivation through TREM2 deficiencyTHY-Tau22小鼠模型在疾病晚期积累了更多的tau蛋白病,以响应通过TREM2缺陷的小胶质细胞失活
Vautheny, Audrey; Duwat, Charlotte; Auregan, Gwennaelle; Josephine, Charlene; Herard, Anne-Sophie; Jan, Caroline; Mitja, Julien; Gipchtein, Pauline; Gaillard, Marie-Claude; Buee, Luc; Blum, David; Hantraye, Philippe; Bonvento, Gilles; Brouillet, Emmanuel; Cambon, Karine; Bemelmans, Alexis-Pierre
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收藏Neuronal tau species transfer to astrocytes and induce their loss according to tau aggregation state
de Gerando, Anastasie Mate; d'Orange, Marie; Augustin, Emma; Josephine, Charlene; Auregan, Gwenaelle; Gaudin-Guerif, Mylene; Guillermier, Martine; Herard, Anne-Sophie; Stimmer, Lev; Petit, Fanny; Gipchtein, Pauline; Jan, Caroline; Escartin, Carole; Selingue, Erwan; Carvalho, Kevin; Blum, David; Brouillet, Emmanuel; Hantraye, Philippe; Gaillard, Marie-Claude; Bonvento, Gilles; Bemelmans, Alexis-Pierre; Cambon, Karine
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收藏Complex roles for reactive astrocytes in the triple transgenic mouse model of Alzheimer disease
Guillemaud, Oceane; Ceyzeriat, Kelly; Saint-Georges, Thomas; Cambon, Karine; Petit, Fanny; Ben Haim, Lucile; Carrillo-de Sauvage, Maria-Angeles; Guillermier, Martine; Bernier, Sueva; Herard, Anne-Sophie; Josephine, Charlene; Bemelmans, Alexis Pierre; Brouillet, Emmanuel; Hantraye, Philippe; Bonvento, Gilles; Escartin, Carole
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收藏Impairment of Glycolysis-Derived L-Serine Production in Astrocytes Contributes to Cognitive Deficits in Alzheimer's Disease
Le Douce, Juliette; Maugard, Marianne; Veran, Julien; Matos, Marco; Jego, Pierrick; Vigneron, Pierre-Antoine; Faivre, Emilie; Toussay, Xavier; Vandenberghe, Michel; Balbastre, Yael; Piquet, Juliette; Guiot, Elvire; Tran, Nguyet Thuy; Taverna, Myriam; Marinesco, Stephane; Koyanagi, Ayumi; Furuya, Shigeki; Gaudin-Guerif, Mylene; Goutal, Sebastien; Ghettas, Aurelie; Pruvost, Alain; Bemelmans, Alexis-Pierre; Gaillard, Marie-Claude; Cambon, Karine; Stimmer, Lev; Sazdovitch, Veronique; Duyckaerts, Charles; Knott, Graham; Herard, Anne-Sophie; Delzescaux, Thierry; Hantraye, Philippe; Brouillet, Emmanuel; Cauli, Bruno; Oliet, Stephane H. R.; Panatier, Aude; Bonvento, Gilles
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收藏The C-terminal domain of LRRK2 with the G2019S mutation is sufficient to produce neurodegeneration of dopaminergic neurons in vivo
Cresto, Noemie; Gaillard, Marie-Claude; Gardier, Camille; Gubinelli, Francesco; Diguet, Elsa; Bellet, Deborah; Legroux, Laurine; Mitja, Julien; Auregan, Gwenaelle; Guillermier, Martine; Josephine, Charlene; Jan, Caroline; Dufour, Noelle; Joliot, Alain; Hantraye, Philippe; Bonvento, Gilles; Deglon, Nicole; Bemelmans, Alexis-Pierre; Cambon, Karine; Liot, Geraldine; Brouillet, Emmanuel
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收藏Encephalopathy induced by Alzheimer brain inoculation in a non-human primate
Gary, Charlotte; Lam, Suzanne; Herard, Anne-Sophie; Koch, James E.; Petit, Fanny; Gipchtein, Pauline; Sawiak, Stephen J.; Caillierez, Raphaelle; Eddarkaoui, Sabiha; Colin, Morvane; Aujard, Fabienne; Deslys, Jean-Philippe; Brouillet, Emmanuel; Buee, Luc; Comoy, Emmanuel E.; Pifferi, Fabien; Picq, Jean-Luc; Dhenain, Marc
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收藏Modulation of astrocyte reactivity improves functional deficits in mouse models of Alzheimer's disease
Ceyzeriat, Kelly; Ben Haim, Lucile; Denizot, Audrey; Pommier, Dylan; Matos, Marco; Guillemaud, Oceane; Palomares, Marie-Ange; Abjean, Laurene; Petit, Fanny; Gipchtein, Pauline; Gaillard, Marie-Claude; Guillermier, Martine; Bernier, Sueva; Gaudin, Mylene; Auregan, Gwenaelle; Josephine, Charlene; Dechamps, Nathalie; Veran, Julien; Langlais, Valentin; Cambon, Karine; Bemelmans, Alexis P.; Baijer, Jan; Bonvento, Gilles; Dhenain, Marc; Deleuze, Jean-Francois; Oliet, Stephane H. R.; Brouillet, Emmanuel; Hantraye, Philippe; Carrillo-de Sauvage, Maria-Angeles; Olaso, Robert; Panatier, Aude; Escartin, Carole
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