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Weiming Xia
H指数:57
被引数:1.7万
个人简介
Completed graduate studies at the University of Texas Medical School at Houston, earning MS and PhD degrees in Biochemistry and Molecular Biology. Postdoctoral training was conducted at Brigham and Women's Hospital, Harvard Medical School. In 1999, the scholar became Assistant Professor of Neurology at Harvard Medical School, establishing an NIH-funded research lab to study Alzheimer's disease. In 2012, the scholar joined the Department of Veterans Affairs Bedford VA Medical Center, leading an independent lab to explore molecular mechanisms and biomarkers for Alzheimer's disease. Research focuses on target identification, characterization, validation, and early stage drug development. Multiple platforms were established to quantify pathological proteins such as amyloid ß protein (Aß), Tau, and neuroinflammatory factors. Mass Spectrometry-based analytic approaches are developed to explore biomarkers for Alzheimer's disease and other central nervous system disorders.
教育背景
暂无内容
工作经历
2012.01 – 至今
Department of Veterans Affairs Bedford VA Medical Center
Professor
1999.01 – 2012.12
Harvard Medical School
Assistant Professor of Neurology
荣誉奖项
- Travel Award（1998）｜Alzheimer's Association International Conference
- Travel Award（1994）
老年退伍军人中轻度认知障碍和阿尔茨海默病后癫痫发作的预测因素：一项回顾性队列研究
在退伍军人事务部医疗保健系统中对患有阿尔茨海默病的老年退伍军人颅内出血事件的识别和表征
Scientific Reports
IF3.9
血浆胶质纤维酸性蛋白与神经丝轻链蛋白与视网膜细胞层厚度的关联：一项眼科手术患者的横断面研究
TMEM106B基因变异改变了慢性创伤性脑病中小胶质细胞的活化和细胞因子反应。
玻璃体STMN2水平反映了死后眼睛和大脑中TDP-43相关的神经退行性变化
阿尔茨海默病的生物标志物在糖尿病视网膜病变患者中上调。
轻度认知障碍患者在向阿尔茨海默病过渡过程中的合并症和载脂蛋白E基因型
铜死亡特征将揭示视神经脊髓炎谱系障碍患者的急性缓解模式
Advanced Science
IF14.1
血浆和眼内液中胶质纤维酸性蛋白及其与玻璃体视网膜疾病患者认知功能的相关性
Scientific Reports
IF3.9
利用诊断编码识别轻认知障碍或阿尔茨海默病痴呆退伍军人急性非创伤性颅内出血事件的可行性
阿尔茨海默病中的岩藻糖苷酶抑制剂
FRONTIERS IN AGING
IF4.3
相对于血浆，眼不同腔室中的神经退行性生物标志物: 一项协议验证研究
在阿尔茨海默氏病的appnl-g-f/MAPTP301S小鼠模型中，β-淀粉样蛋白的积累可增强微管相关蛋白tau的病理
