L. Darryl Quarles - Publications, H-index & Citations

L. Darryl Quarles

University of Tennessee System

81H指数

309论文数

2.3W被引数

收录论文 121

发表时间

Mechanical protein polycystin-1 directly regulates osteoclastogenesis and bone resorption 机械蛋白polycystin-1直接调节破骨细胞生成和骨吸收

SCIENCE BULLETIN

IF21.1

2024-06-01

OAAI

Huang, Mei; Zhou, Jingxuan; Li, Xiaoxiao; Liu, Ran; Jiang, Yangzi; Chen, Kaixuan; Jiao, Yurui; Yin, Xin; Liu, Ling; Sun, Yuchen; Wang, Weishan; Xiao, Ye; Su, Tian; Guo, Qi; Huang, Yan; Yang, Mi; Wei, Jie; Quarles, L. Darryl; Xiao, Zhousheng; Zeng, Chao; Luo, Xianghang; Lei, Guanghua; Li, Changjun

Drugging the entire human proteome: Are we there yet?

DRUG DISCOVERY TODAY

IF7.5

2024-03-01

OAAI

Smith, Micholas Dean; Quarles, L. Darryl; Demerdash, Omar; Smith, Jeremy C.

Systems genetics and bioinformatics analyses using ESR1-correlated genes identify potential candidates underlying female bone development

GENOMICS

IF3

2024-01-01

OAAI

Bajpai, Akhilesh K.; Gu, Qingqing; Jiao, Yan; Starlard-Davenport, Athena; Gu, Weikuan; Quarles, Leigh Darryl; Xiao, Zhousheng; Lu, Lu

Structural asymmetry in FGF23 signaling

TRENDS IN PHARMACOLOGICAL SCIENCES

IF19.9

2023-12-01

OAAI

Liu, Shih-Hsien; Xiao, Zhousheng; Smith, Jeremy C.; Quarles, Darryl

Genetic interactions between polycystin-1 and Wwtr1 in osteoblasts define a novel mechanosensing mechanism regulating bone formation in mice

BONE RESEARCH

IF15

2023-10-26

OAAI

Xiao, Zhousheng; Cao, Li; Smith, Micholas Dean; Li, Hanxuan; Li, Wei; Smith, Jeremy C.; Quarles, Leigh Darryl

Gene network based analysis identifies a coexpression module involved in regulating plasma lipids with high-fat diet response

JOURNAL OF NUTRITIONAL BIOCHEMISTRY

IF4.9

2023-09-01

PREAI

Xu, Fuyi; Ziebarth, Jesse; Goeminne, Ludger J. E.; Gao, Jun; Williams, Evan G.; Quarles, Leigh; Makowski, Liza; Cui, Yan; Williams, Robert W.; Auwerx, Johan; Lu, Lu

Loss of Smad3-mediated negative regulation of Runx2 activity leads to an alteration in cell fate determination

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Hjelmeland, AB; Schilling, SH; Guo, X; Quarles, D; Wang, XF

Identification of Small-Molecule Inhibitors of Fibroblast Growth Factor 23 Signaling via In Silico Hot Spot Prediction and Molecular Docking to α-Klotho

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2022-07-22

OAAI

Liu, Shih-Hsien; Xiao, Zhousheng; Mishra, Sambit K.; Mitchell, Julie C.; Smith, Jeremy C.; Quarles, L. Darryl; Petridis, Loukas

Osteoporosis: Mechanism, Molecular Target and Current Status on Drug Development

CURRENT MEDICINAL CHEMISTRY

IF3.5

2021-03-01

174

OAAI

Li, Hanxuan; Xiao, Zhousheng; Quarles, L. Darryl; Li, Wei

Explaining Divergent Observations Regarding Osteocalcin/GPRC6A Endocrine Signaling

ENDOCRINOLOGY

IF3.3

2021-01-20

OAAI

Pi, Min; Nishimoto, Satoru Kenneth; Quarles, L. Darryl

Design and development of FGF-23 antagonists: Definition of the pharmacophore and initial structure-activity relationships probed by synthetic analogues

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2021-01-01

OAAI

Downs, Ryan P.; Xiao, Zhousheng; Ikedionwu, Munachi O.; Cleveland, Jacob W.; Chin, Ai Lin; Cafferty, Abigail E.; Quarles, L. Darryl; Carrick, Jesse D.

Molecular dynamics analysis of the binding of human interleukin-6 with interleukin-6α-receptor

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

IF2.8

2020-09-16

OAAI

Gupta, Madhulika; Ha, Khanh; Agarwal, Rupesh; Quarles, Leigh Darryl; Smith, Jeremy C.

Humanized GPRC6AKGKY is a gain-of-function polymorphism in mice

SCIENTIFIC REPORTS

IF3.9

2020-07-07

OAAI

Pi, Min; Xu, Fuyi; Ye, Ruisong; Nishimoto, Satoru K.; Kesterson, Robert A.; Williams, Robert W.; Lu, Lu; Quarles, L. Darryl

Role of GPRC6A in Regulating Hepatic Energy Metabolism in Mice

SCIENTIFIC REPORTS

IF3.9

2020-04-29

OAAI

Pi, Min; Xu, Fuyi; Ye, Ruisong; Nishimoto, Satoru K.; Williams, Robert W.; Lu, Lu; Quarles, L. Darryl

FGF23 induced left ventricular hypertrophy mediated by FGFR4 signaling in the myocardium is attenuated by soluble Klotho in mice

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

IF4.7

2020-01-01

OAAI

Han, Xiaobin; Cai, Chun; Xiao, Zhousheng; Quarles, L. Darryl

FGF23 expression is stimulated in transgenic α-Klotho longevity mouse model

JCI INSIGHT

IF6.1

2019-12-05

OAAI

Xiao, Zhousheng; King, Gwendalyn; Mancarella, Salvatore; Munkhsaikhan, Undral; Cao, Li; Cai, Chun; Quarles, Leigh Darryl

Human GPRC6A Mediates Testosterone-Induced Mitogen-Activated Protein Kinases and mTORC1 Signaling in Prostate Cancer Cells

MOLECULAR PHARMACOLOGY

IF3

2019-05-01

OAAI

Ye, Ruisong; Pi, Min; Nooh, Mohammed M.; Bahout, Suleiman W.; Quarles, L. Darryl

Validation of a Novel Modified Aptamer-Based Array Proteomic Platform in Patients with End-Stage Renal Disease 基于核酸适配子的新型阵列蛋白质组学平台在终末期肾病患者中的验证

DIAGNOSTICS

IF3.3

2018-10-08

OAAI

Han, Zhongji; Xiao, Zhousheng; Kalantar-Zadeh, Kamyar; Moradi, Hamid; Shafi, Tariq; Waikar, Sushrut S.; Quarles, L. Darryl; Yu, Zhi; Tin, Adrienne; Coresh, Josef; Kovesdy, Csaba P.

Letter to the Editor: Increased Circulating FGF23 Does Not Lead to Cardiac Hypertrophy in the Male Hyp Mouse Model of XLH

ENDOCRINOLOGY

IF3.3

2018-09-20

OAAI

Han, Xiaobin; Quarles, L. Darryl

Cardiovascular Interactions between Fibroblast Growth Factor-23 and Angiotensin II

SCIENTIFIC REPORTS

IF3.9

2018-08-17

OAAI

Pi, Min; Ye, Ruisong; Han, Xiaobin; Armstrong, Benjamin; Liu, Xue; Chen, Yuanjian; Sun, Yao; Quarles, L. Darryl

研究方向