David G. Brooks - Publications, H-index & Citations

David G. Brooks

university health network toronto

59H指数

185论文数

1.4W被引数

收录论文 95

发表时间

Guidelines for T cell nomenclature T细胞命名指南

Nature Reviews Immunology

IF60.9

2025-11-18

OAAI

David Masopust; Amit Awasthi; Rémy Bosselut; David G. Brooks; Marcus Buggert; Kenji Chamoto; Weiguo Cui; Chen Dong; Donna L. Farber; Thomas Gebhardt; Carmen Gerlach; Ananda Goldrath; Philip D. Greenberg; J. Scott Hale; Adrian Hayday; Dirk Homann; Matteo Iannacone; Stephen C. Jameson; Marc K. Jenkins; Nikhil S. Joshi; Susan M. Kaech; Axel Kallies; Alice O. Kamphorst; Mark H. Kaplan; Paul Klenerman; Marco Künzli; Antonio Lanzavecchia; Georg M. Lauer; Enrico Lugli; Andrew D. Luster; Laura K. Mackay; M. Juliana McElrath; Scott N. Mueller; Zaza Ndhlovu; Thumbi Ndung’u; Pamela S. Ohashi; Annette Oxenius; Giuseppe Pantaleo; Marion Pepper; Louis J. Picker; Clare F. Quarnstrom; Gustavo Reyes-Terán; Mario Roederer; Pamela C. Rosato; Gonzalo Salgado-Montes de Oca; Federica Sallusto; Ton N. Schumacher; Daniella M. Schwartz; Eui-Cheol Shin; Andrew G. Soerens; Daniela S. Thommen; Vaiva Vezys; João P. B. Viola; Bruce D. Walker; Tania H. Watts; Casey T. Weaver; E. John Wherry; Hai-Hui Xue; Ben Youngblood; Rafi Ahmed

IRF2 expression in Tregs limits the antiviral immune response to prevent mortality during chronic infection

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-01

PREAI

Elsaesser, Heidi J.; Brooks, David G.

Cytotoxic CD4 T cells in acute and chronic viral infection

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-01

PREAI

Liu, Melissa; Brooks, David G.

Cross-Cancer Analysis Reveals a Distinct Pattern of Immune Modulation During Curative Radiation Therapy 跨癌症分析揭示了根治性放射治疗期间免疫调节的独特模式

international journal of radiation oncology biology physics

IF0

2025-09-19

PREAI

Badr Id Said; Giselle M. Boukhaled; Benjamin H. Lok; Jelena Lukovic; Aruz Mesci; John Waldron; Philip Wong; Ben X. Wang; David G. Brooks; Michael Milosevic

Obesity intensifies sex-specific interferon signaling to selectively worsen central nervous system autoimmunity in females

CELL METABOLISM

IF30.9

2024-10-01

OAAI

Cordeiro, Brendan; Ahn, Jeeyoon Jennifer; Gawde, Saurabh; Ucciferri, Carmen; Alvarez-Sanchez, Nuria; Revelo, Xavier S.; Stickle, Natalie; Massey, Kaylea; Brooks, David G.; Guthridge, Joel M.; Pardo, Gabriel; Winer, Daniel A.; Axtell, Robert C.; Dunn, Shannon E.

GNAS knockout potentiates HDAC3 inhibition through viral mimicry-related interferon responses in lymphoma

LEUKEMIA

IF13.4

2024-08-08

OAAI

He, Michael Y.; Tong, Kit I.; Liu, Ting; Whittaker Hawkins, Ryder; Shelton, Victoria; Zeng, Yong; Bakhtiari, Mehran; Xiao, Yufeng; Zheng, Guangrong; Sakhdari, Ali; Yang, Lin; Xu, Wenxi; Brooks, David G.; Laister, Rob C.; He, Housheng Hansen; Kridel, Robert

Regulation and impact of tumor-specific CD4+T cells in cancer and immunotherapy

TRENDS IN IMMUNOLOGY

IF13.9

2024-04-01

PREAI

Guo, Mengdi; Liu, Melissa Yi Ran; Brooks, David G.

IL-2 produced by HBV-specific T cells as a biomarker of viral control and predictor of response to PD-1 therapy across clinical phases of chronic hepatitis B 由HBV特异性T细胞产生的IL-2作为病毒控制的生物标志物和慢性乙型肝炎临床阶段对PD-1治疗反应的预测

HEPATOLOGY COMMUNICATIONS

IF4.6

2023-12-01

OAAI

Chua, Conan; Salimzadeh, Loghman; Ma, Ann T.; Adeyi, Oyedele A.; Seo, Hobin; Boukhaled, Giselle M.; Mehrotra, Aman; Patel, Anjali; Ferrando-Martinez, Sara; Robbins, Scott H.; La, Danie; Wong, David; Janssen, Harry L. A.; Brooks, David G.; Feld, Jordan J.; Gehring, Adam J.

Molecular, metabolic, and functional CD4 T cell paralysis in the lymph node impedes tumor control

CELL REPORTS

IF6.9

2023-09-01

OAAI

Guo, Mengdi; Abd-Rabbo, Diala; Bertol, Bruna C.; Carew, Madeleine; Lukhele, Sabelo; Snell, Laura M.; Xu, Wenxi; Boukhaled, Giselle M.; Elsaesser, Heidi; Halaby, Marie Jo; Hirano, Naoto; Mcgaha, Tracy L.; Brooks, David G.

Medullary sinus macrophages limit cancer therapy efficacy by an efferocytosis-induced IL-33/ST2 axis in the tumor-draining lymph node

JOURNAL OF IMMUNOLOGY

IF3.4

2023-05-01

OAAI

Lamorte, Sara; Neufeld, Luke; Quevedo, Rene; Zhang, Xin; Ciudad, M. Teresa; Jin, Robbie; Saeed, Zaid Kamil; Karlsson, Mikael C. I.; Mak, Tak W.; Munn, David; Brooks, David; McGaha, Tracy

The transcription factor IRF2 drives interferon-mediated CD8+T cell exhaustion to restrict anti-tumor immunity 转录因子IRF2驱动干扰素介导的CD8 T细胞耗竭以限制抗肿瘤免疫

IMMUNITY

IF26.3

2022-12-01

OAAI

Lukhele, Sabelo; Abd Rabbo, Diala; Guo, Mengdi; Shen, Jian; Elsaesser, Heidi J.; Quevedo, Rene; Carew, Madeleine; Gadalla, Ramy; Snell, Laura M.; Mahesh, Lawanya; Ciudad, M. Teresa; Snow, Bryan E.; You-Ten, Annick; Haight, Jillian; Wakeham, Andrew; Ohashi, Pamela S.; Mak, Tak W.; Cui, Weiguo; McGaha, Tracy L.; Brooks, David G.

Biomarker opportunities in the treatment of cancer-related depression

Trends in Molecular Medicine

IF13.8

2022-12-01

PREAI

Panjwani, Aliza A.; Aguiar, Stefan; Gascon, Bryan; Brooks, David G.; Li, Madeline

Pre-encoded responsiveness to type I interferon in the peripheral immune system defines outcome of PD1 blockade therapy 外周免疫系统中对I型干扰素的预编码反应性定义了PD1阻断治疗的结果

NATURE IMMUNOLOGY

IF27.6

2022-07-14

PREAI

Boukhaled, Giselle M.; Gadalla, Ramy; Elsaesser, Heidi J.; Abd-Rabbo, Diala; Quevedo, Rene; Yang, S. Y. Cindy; Guo, Mengdi; Wang, Ben X.; Noamani, Babak; Gray, Diana; Lau, Sally C. M.; Taylor, Kirsty; Aung, Kyaw; Spreafico, Anna; Hansen, Aaron R.; Saibil, Samuel D.; Hirano, Naoto; Guidos, Cynthia; Pugh, Trevor J.; McGaha, Tracy L.; Ohashi, Pamela S.; Sacher, Adrian G.; Butler, Marcus O.; Brooks, David G.

Peripheral CD4 T cell resistance to type I interferon defines outcome of PD1 blockade therapy in human cancer

JOURNAL OF IMMUNOLOGY

IF3.4

2022-05-01

PREAI

Boukhaled, Giselle M.; Gadalla, Ramy; Elsaesser, Heidi J.; Sacher, Adrian; Butler, Marcus O.; Brooks, David G.

DC1s shield Tpex cells to bolster PD-1 blockade

IMMUNITY

IF26.3

2022-04-01

OAAI

Brooks, David G.; Ohashi, Pamela S.

Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity 色氨酸衍生的微生物代谢物激活肿瘤相关巨噬细胞中的芳香烃受体以抑制抗肿瘤免疫

IMMUNITY

IF26.3

2022-02-01

288

OAAI

Hezaveh, Kebria; Shinde, Rahul S.; Kloetgen, Andreas; Halaby, Marie Jo; Lamorte, Sara; Ciudad, M. Teresa; Quevedo, Rene; Neufeld, Luke; Liu, Zhe Qi; Jin, Robbie; Grunwald, Barbara T.; Foerster, Elisabeth G.; Chaharlangi, Danica; Guo, Mengdi; Makhijani, Priya; Zhang, Xin; Pugh, Trevor J.; Pinto, Devanand M.; Co, Ileana L.; McGuigan, Alison P.; Jang, Gun Ho; Khokha, Rama; Ohashi, Pamela S.; O'Kane, Grainne M.; Gallinger, Steven; Navarre, William W.; Maughan, Heather; Philpott, Dana J.; Brooks, David G.; McGaha, Tracy L.

Dynamic CD4+ T cell heterogeneity defines subset-specific suppression and PD-L1-blockade-driven functional restoration in chronic infection

NATURE IMMUNOLOGY

IF27.6

2021-11-18

OAAI

Snell, Laura M.; Xu, Wenxi; Abd-Rabbo, Diala; Boukhaled, Giselle; Guo, Mengdi; Macleod, Bethany L.; Elsaesser, Heidi J.; Hezaveh, Kebria; Alsahafi, Nirmin; Lukhele, Sabelo; Nejat, Sara; Prabhakaran, Ramanandan; Epelman, Slava; McGaha, Tracy L.; Brooks, David G.

Pan-cancer analysis of longitudinal metastatic tumors reveals genomic alterations and immune landscape dynamics associated with pembrolizumab sensitivity

NATURE COMMUNICATIONS

IF15.7

2021-08-26

OAAI

Yang, S. Y. Cindy; Lien, Scott C.; Wang, Ben X.; Clouthier, Derek L.; Hanna, Youstina; Cirlan, Iulia; Zhu, Kelsey; Bruce, Jeffrey P.; El Ghamrasni, Samah; Iafolla, Marco A. J.; Oliva, Marc; Hansen, Aaron R.; Spreafico, Anna; Bedard, Philippe L.; Lheureux, Stephanie; Razak, Albiruni; Speers, Vanessa; Berman, Hal K.; Aleshin, Alexey; Haibe-Kains, Benjamin; Brooks, David G.; McGaha, Tracy L.; Butler, Marcus O.; Bratman, Scott, V; Ohashi, Pamela S.; Siu, Lillian L.; Pugh, Trevor J.

Prevention of CD8 T Cell Deletion during Chronic Viral Infection

VIRUSES-BASEL

IF3.5

2021-06-22

OAAI

Brooks, David G.; Tishon, Antoinette; Oldstone, Michael B. A.; McGavern, Dorian B.

DNA hypomethylating agents increase activation and cytolytic activity of CD8+T cells

MOLECULAR CELL

IF16.6

2021-04-01

OAAI

Yau, Helen Loo; Bell, Emma; Ettayebi, Ilias; de Almeida, Felipe Campos; Boukhaled, Giselle M.; Shen, Shu Yi; Allard, David; Morancho, Beatriz; Marhon, Sajid A.; Ishak, Charles A.; Gonzaga, Isabela M.; Medina, Tiago da Silva; Singhania, Rajat; Chakravarthy, Ankur; Chen, Raymond; Mehdipour, Parinaz; Pommey, Sandra; Klein, Christian; Amarante-Mendes, Gustavo P.; Roulois, David; Arribas, Joaquin; Stagg, John; Brooks, David G.; De Carvalho, Daniel D.

研究方向