arrow
返回
T

Thomas Reinheckel

german cancer consortium (dktk)

68H指数
265论文数
1.8W被引数
收录论文 135
发表时间
Hyperpolarization of [1-13C]Ketoisocaproate-d2 by Reversible Exchange with Parahydrogen Enables Profiling of Branched-Chain-Amino-Acid Metabolism in Cellulo and in Vivo[1-13C]α-酮异己酸-d2通过顺磁氢的可逆交换实现超极化,从而在细胞内和活体中实现对支链氨基酸代谢的表征
err2026-06-23
err0
errOAAI
errStefan Petersen; Philipp R. Groß; Paul M. Schmidt; Henri de Maissin; Asitan Rittinger; Robert Willing; Adriana Sacristán-Martín; Lisa Heß; Jule Koch; Sebastian Lucas; Maxim Zaitsev; Dominik von Elverfeldt; Martin Grashei; Franz Schilling; Jan-Bernd Hövener; André F. Martins; Max von Delius; Thomas Reinheckel; Andreas B. Schmidt
err分享
err收藏
Dipeptidyl peptidase 9 (DPP9) depletion from hepatocytes in experimental primary liver cancer实验性原发性肝癌中二肽基肽酶9(DPP9)从肝细胞中的耗竭
err2025-06-01
err1
errOAAI
errHuang, JiaLi Carrie; Tong, Xinlin Linda; Xiang, Michelle Sui Wen; Boumelhem, Badwi B.; Foulis, Diarmid P.; Zhang, MingChang; McKenzie, Catriona A.; McCaughan, Geoffrey W.; Reinheckel, Thomas; Zhang, Hui E.; Gorrell, Mark D.
err分享
err收藏
Cathepsin D inhibition during neuronal differentiation selectively affects individual proteins instead of overall protein turnover
err2024-11-01
err0
errOAAI
errSchneider, Johannes; Mitschke, Julia; Bhat, Mahima; Vogele, Daniel; Schilling, Oliver; Reinheckel, Thomas; Hess, Lisa
err分享
err收藏
Signal Amplification by Reversible Exchange and its Translation to Hyperpolarized Magnetic Resonance Imaging in Biomedicine生物医学中可逆交换的信号放大及其对超极化磁共振成像的转化
err2024-10-10
err3
errOAAI
errSchmidt, Andreas B.; Chekmenev, Eduard Y.; de Maissin, Henri; Gross, Philipp R.; Petersen, Stefan; Nagel, Luca; Schilling, Franz; Schwartz, Ilai; Reinheckel, Thomas; Hoevener, Jan-Bernd; Knecht, Stephan
err分享
err收藏
Cathepsin D is essential for the degradomic shift of macrophages required to resolve liver fibrosis
err2024-09-01
err4
errOAAI
errRuiz-Blazquez, Paloma; Fernandez-Fernandez, Maria; Pistorio, Valeria; Martinez-Sanchez, Celia; Costanzo, Michele; Iruzubieta, Paula; Zhuravleva, Ekaterina; Cacho-Pujol, Julia; Arino, Silvia; Del Castillo-Cruz, Alejandro; Nunez, Susana; Andersen, Jesper B.; Ruoppolo, Margherita; Crespo, Javier; Garcia-Ruiz, Carmen; Pavone, Luigi Michele; Reinheckel, Thomas; Sancho-Bru, Pau; Coll, Mar; Fernandez-Checa, Jose C.; Moles, Anna
err分享
err收藏
Inhibition of cysteine protease cathepsin Lincreases the level and activity of lysosomal glucocerebrosidase
err2024-02-08
err2
errOAAI
errKim, Myung Jong; Kim, Soojin; Reinheckel, Thomas; Krainc, Dimitri
err分享
err收藏
Dipeptidyl-Aminopeptidases 8 and 9 Regulate Autophagy and Tamoxifen Response in Breast Cancer Cells
errCELLS
IF5.2
err2023-08-10
err3
errOAAI
errBettecken, Aaron; Hess, Lisa; Hoelzen, Lena; Reinheckel, Thomas
err分享
err收藏
In Vivo Metabolic Imaging of [1-13C]Pyruvate-d3 Hyperpolarized By Reversible Exchange With Parahydrogen
err2023-07-25
err36
errOAAI
errde Maissin, Henri; Gross, Philipp R.; Mohiuddin, Obaid; Weigt, Moritz; Nagel, Luca; Herzog, Marvin; Wang, Zirun; Willing, Robert; Reichardt, Wilfried; Pichotka, Martin; Hess, Lisa; Reinheckel, Thomas; Jessen, Henning J.; Zeiser, Robert; Bock, Michael; von Elverfeldt, Dominik; Zaitsev, Maxim; Korchak, Sergey; Gloeggler, Stefan; Hoevener, Jan-Bernd; Chekmenev, Eduard Y.; Schilling, Franz; Knecht, Stephan; Schmidt, Andreas B.
err分享
err收藏
Tyrosine kinase inhibitors can activate the NLRP3 inflammasome in myeloid cells through lysosomal damage and cell lysis
err2023-01-17
err12
PREAI
errNeuwirt, Emilia; Magnani, Giovanni; Cikovic, Tamara; Woehrle, Svenja; Fischer, Larissa; Kostina, Anna; Flemming, Stephan; Fischenich, Nora J.; Saller, Benedikt S.; Gorka, Oliver; Renner, Steffen; Agarinis, Claudia; Parker, Christian N.; Boettcher, Andreas; Farady, Christopher J.; Kesselring, Rebecca; Berlin, Christopher; Backofen, Rolf; Rodriguez-Franco, Marta; Kreutz, Clemens; Prinz, Marco; Tholen, Martina; Reinheckel, Thomas; Ott, Thomas; Gross, Christina J.; Jost, Philipp J.; Gross, Olaf
err分享
err收藏
Lysosomal damage drives mitochondrial proteome remodelling and reprograms macrophage immunometabolism
err2022-11-28
err24
errOAAI
errBussi, Claudio; Heunis, Tiaan; Pellegrino, Enrica; Bernard, Elliott M.; Bah, Nourdine; Dos Santos, Mariana Silva; Santucci, Pierre; Aylan, Beren; Rodgers, Angela; Fearns, Antony; Mitschke, Julia; Moore, Christopher; MacRae, James, I; Greco, Maria; Reinheckel, Thomas; Trost, Matthias; Gutierrez, Maximiliano G.
err分享
err收藏
Degradome-focused RNA interference screens to identify proteases important for breast cancer cell growth
err2022-10-12
err2
errOAAI
errHoelzen, Lena; Syre, Kerstin; Mitschke, Jan; Brummer, Tilman; Miething, Cornelius; Reinheckel, Thomas
err分享
err收藏
Cathepsin B Gene Knockout Improves Behavioral Deficits and Reduces Pathology in Models of Neurologic Disorders
err2022-07-01
err43
errOAAI
errHook, Gregory; Reinheckel, Thomas; Ni, Junjun; Wu, Zhou; Kindy, Mark; Peters, Christoph; Hook, Vivian
err分享
err收藏
Differential regulation of progranulin derived granulin peptides
err2022-02-04
err18
errOAAI
errZhang, Tingting; Du, Huan; Santos, Mariela Nunez; Wu, Xiaochun; Pagan, Mitchell D.; Trigiani, Lianne Jillian; Nishimura, Nozomi; Reinheckel, Thomas; Hu, Fenghua
err分享
err收藏
RNA interference screens discover proteases as synthetic lethal partners of PI3K inhibition in breast cancer cells
err2022-01-01
err5
errOAAI
errHoelzen, Lena; Mitschke, Jan; Schoenichen, Claudia; Hess, Maria Elena; Ehrenfeld, Sophia; Boerries, Melanie; Miething, Cornelius; Brummer, Tilman; Reinheckel, Thomas
err分享
err收藏
Cathepsin H deficiency decreases hypoxia-ischemia-induced hippocampal atrophy in neonatal mice through attenuated TLR3/IFN-β signaling
err2021-08-10
err13
errOAAI
errNi, Junjun; Zhao, Juan; Zhang, Xinwen; Reinheckel, Thomas; Turk, Vito; Nakanishi, Hiroshi
err分享
err收藏
A 9-kDa matricellular SPARC fragment released by cathepsin D exhibits pro-tumor activity in the triple-negative breast cancer microenvironment
err2021-01-01
err22
errOAAI
errAlcaraz, Lindsay B.; Mallavialle, Aude; David, Timothee; Derocq, Danielle; Delolme, Frederic; Dieryckx, Cindy; Mollevi, Caroline; Boissiere-Michot, Florence; Simony-Lafontaine, Joelle; Du Manoir, Stanislas; Huesgen, Pitter F.; Overall, Christopher M.; Tartare-Deckert, Sophie; Jacot, William; Chardes, Thierry; Guiu, Severine; Roger, Pascal; Reinheckel, Thomas; Moali, Catherine; Liaudet-Coopman, Emmanuelle
err分享
err收藏
Cathepsin D deficiency in mammary epithelium transiently stalls breast cancer by interference with mTORC1 signaling
err2020-10-12
err38
errOAAI
errKetterer, Stephanie; Mitschke, Julia; Ketscher, Anett; Schlimpert, Manuel; Reichardt, Wilfried; Baeuerle, Natascha; Hess, Maria Elena; Metzger, Patrick; Boerries, Melanie; Peters, Christoph; Kammerer, Bernd; Brummer, Tilman; Steinberg, Florian; Reinheckel, Thomas
err分享
err收藏
BRAFV600E drives dedifferentiation in small intestinal and colonic organoids and cooperates with mutant p53 and Apc loss in transformation
err2020-08-13
err21
errOAAI
errReischmann, Nadine; Andrieux, Geoffroy; Griffin, Ricarda; Reinheckel, Thomas; Boerries, Melanie; Brummer, Tilman
err分享
err收藏
The secreted inhibitor of invasive cell growth CREG1 is negatively regulated by cathepsin proteases
err2020-05-08
err7
errOAAI
errGomez-Auli, Alejandro; Hillebrand, Larissa Elisabeth; Christen, Daniel; Guenther, Sira Carolin; Biniossek, Martin Lothar; Peters, Christoph; Schilling, Oliver; Reinheckel, Thomas
err分享
err收藏
Intracellular cathepsin C levels determine sensitivity of cells to leucyl-leucine methyl ester-triggered apoptosis
err2020-05-01
err17
errOAAI
errKavcic, Nezka; Butinar, Miha; Sobotic, Barbara; Hafner Cesen, Marusa; Petelin, Ana; Bojic, Lea; Zavasnik Bergant, Tina; Bratovs, Andreja; Reinheckel, Thomas; Turk, Boris
err分享
err收藏