Mark C. Chappell - Publications, H-index & Citations

Mark C. Chappell

Wake Forest University School of Medicine

70H指数

374论文数

2.1W被引数

收录论文 103

发表时间

A pilot study of circulating DPP3 and renin to identify high-risk phenotypes and mortality in septic shock 关于循环DPP3和肾素用于识别脓毒性休克高危表型与死亡率的初步研究

Critical Care

IF9.3

2026-08-27

OAAI

Christopher L. Schaich; Mark C. Chappell; Shriram S. Mahabal; D. Clark Files; Kendra N. Wright; Lane M. Smith; Ashish K. Khanna

Renin-Angiotensin-Aldosterone Medication Use and Outcomes in Injured Patients Receiving Blood 肾素-血管紧张素-醛固酮药物使用与接受输血的受伤患者结局

Journal of Surgical Research

IF1.7

2026-05-01

PREAI

Werenski, Hope E.; Diz, Debra I.; Chappell, Mark C.; Hoth, J. Jason; Avery, Martin D.; Nunn, Andrew M.; Stettler, Gregory R.

Attenuated renin response and reduced angiotensin II concentrations: association with cardiopulmonary bypass-induced vasoplegia 肾素反应减弱和血管紧张素II浓度降低：与心肺 bypass 诱导的血管麻痹综合征的关联

British Journal of Anaesthesia

IF9.2

2025-09-25

PREAI

Bartlomiej R. Imielski; Ashish K. Khanna; Spencer Tingey; Christopher L. Schaich; Kendra N. Wright; Alexander Zarbock; Mark C. Chappell

The circulating renin-angiotensin system and mortality among patients hospitalized for COVID-19: a mechanistic substudy of the ACTIV-4 Host Tissue trials 循环肾素-血管紧张素系统与因COVID-19住院患者的死亡率：ACTIV-4宿主组织试验的一项机制性亚研究

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

IF3.5

2025-03-01

PREAI

Schaich, CL; Chappell, MC; Shotwell, MS; Joly, MM; Gibbs, KW; Barksdale, A; Douglas, IS; Chen, PT; Levitt, JE; Puskarich, MA; Rice, TW; Harkins, MS; Hudock, KM; Lanspa, MJ; Ginde, AA; Self, WH; Collins, SP; Files, DC

Reply to: angiotensinogen: a new era beyond lactate as a biomarker?

CRITICAL CARE

IF9.3

2024-12-16

OAAI

Chappell, Mark C.; Schaich, Christopher L.; Khanna, Ashish K.

Stronger association of intact angiotensinogen with mortality than lactate or renin in critical illness: post-hoc analysis from the VICTAS trial

CRITICAL CARE

IF9.3

2024-10-14

OAAI

Chappell, Mark C.; Schaich, Christopher L.; Busse, Laurence W.; Martin, Greg S.; Sevransky, Jonathan E.; Hinson, Jeremiah K.; Khanna, Ashish K.

Stronger Association of Angiotensinogen with Mortality than Renin or Lactate in Critical Illness

HYPERTENSION

IF8.2

2024-09-01

PREAI

Chappell, Mark; Schaich, Christopher; Busse, Laurence; McCurdy, Michael; Hinson, Jeremiah; Sevransky, Jonathan; Rothman, Richard; Wright, David; Martin, Gregory Scott; Khanna, Ashish

Renin in critically ill patients

ANNALS OF INTENSIVE CARE

IF5.5

2024-05-22

OAAI

Kotani, Yuki; Chappell, Mark; Landoni, Giovanni; Zarbock, Alexander; Bellomo, Rinaldo; Khanna, Ashish K.

ACE inhibitors and angiotensin receptor blockers differentially alter the response to angiotensin II treatment in vasodilatory shock

CRITICAL CARE

IF9.3

2024-04-18

OAAI

Leisman, Daniel E.; Handisides, Damian R.; Busse, Laurence W.; Chappell, Mark C.; Chawla, Lakhmir S.; Filbin, Michael R.; Goldberg, Marcia B.; Ham, Kealy R.; Khanna, Ashish K.; Ostermann, Marlies; Mccurdy, Michael T.; Adams, Christopher D.; Hodges, Tony N.; Bellomo, Rinaldo

Higher Circulating Angiotensin Converting Enzyme 2 (ACE2) and ACE2 to ACE Ratio Are Associated With Lower COVID-19 Mortality: A Mechanistic Substudy of the ACTIV-4 Host Tissue Trials

CIRCULATION

IF38.6

2024-03-19

PREAI

Schaich, Christopher L.; Files, D. Clark; Shotwell, Matthew S.; Joly, Meghan M.; Gibbs, Kevin W.; Self, Wesley H.; Collins, Sean P.; Chappell, Mark C.

The role of preterm birth in stress-induced sodium excretion in young adults

JOURNAL OF HYPERTENSION

IF4.1

2024-02-28

PREAI

Tully, Nicholas W.; Chappell, Mark C.; Evans, Joni K.; Jensen, Elizabeth T.; Shaltout, Hossam A.; Washburn, Lisa K.; South, Andrew M.

Association of Active Renin Content With Mortality in Critically Ill Patients: A Post hoc Analysis of the Vitamin C, Thiamine, and Steroids in Sepsis (VICTAS) Trial

CRITICAL CARE MEDICINE

IF6

2023-11-10

OAAI

Busse, Laurence W.; Schaich, Christopher L.; Chappell, Mark C.; McCurdy, Michael T.; Staples, Erin M.; Ten Lohuis, Caitlin C.; Hinson, Jeremiah S.; Sevransky, Jonathan E.; Rothman, Richard E.; Wright, David W.; Martin, Greg S.; Khanna, Ashish K.

Renin-Angiotensin System and Sex Differences in COVID-19: A Critical Assessment

CIRCULATION RESEARCH

IF16.2

2023-05-12

OAAI

Chappell, Mark C.

Discrete Correlation Summation Clustering Reveals Differential Regulation of Liver Metabolism by Thrombospondin-1 in Low-Fat and High-Fat Diet-Fed Mice 离散相关求和聚类揭示了低脂和高脂饮食喂养的小鼠中Thrombospondin-1对肝脏代谢的差异调节

METABOLITES

IF3.7

2022-10-28

OAAI

Bronson, Steven M.; Westwood, Brian; Cook, Katherine L.; Emenaker, Nancy J.; Chappell, Mark C.; Roberts, David D.; Soto-Pantoja, David R.

Targeted UHPLC-MS Analysis Reveals Disparate Polyphenol Composition and Concentration in Muscadine Grape Supplements with Proportional Antioxidant Activity

ANTIOXIDANTS

IF6.6

2022-10-27

OAAI

Chappell, Mark C.; Duncan, Aja, V; Melo, Ana Clara; Schaich, Christopher L.; Pirro, Nancy T.; Diz, Debra, I; Tallant, E. Ann; Gallagher, Patricia E.

The Renin-Angiotensin-Aldosterone System in COVID-19-related and Non-COVID-19-related Acute Respiratory Distress Syndrome Not So Different after All?

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

IF19.4

2021-11-01

OAAI

Collins, Sean P.; Chappell, Mark C.; Files, D. Clark

Human Urinary Exosomes Contain Functional ACE2

HYPERTENSION

IF8.2

2021-09-01

PREAI

Okechukwu, Charles C.; Pirro, Nancy T.; Chappell, Mark C.; Yamaleyeva, Liliya M.

Gut dysbiosis and hypertension: is it cause or effect?

JOURNAL OF HYPERTENSION

IF4.1

2021-09-01

OAAI

Cook, Katherine L.; Chappell, Mark C.

A pilot study to assess the circulating renin-angiotensin system in COVID-19 acute respiratory failure

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

IF3.5

2021-07-01

OAAI

Files, D. Clark; Gibbs, Kevin W.; Schaich, Christopher L.; Collins, Sean P.; Gwathmey, TanYa M.; Casey, Jonathan D.; Self, Wesley H.; Chappell, Mark C.

Diet, obesity, and the gut microbiome as determinants modulating metabolic outcomes in a non-human primate model

MICROBIOME

IF12.7

2021-05-05

OAAI

Newman, Tiffany M.; Shively, Carol A.; Register, Thomas C.; Appt, Susan E.; Yadav, Hariom; Colwell, Rita R.; Fanelli, Brian; Dadlani, Manoj; Graubics, Karlis; Nguyen, Uyen Thao; Ramamoorthy, Sivapriya; Uberseder, Beth; Clear, Kenysha Y. J.; Wilson, Adam S.; Reeves, Kimberly D.; Chappell, Mark C.; Tooze, Janet A.; Cook, Katherine L.

研究方向