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C

Christoph E. Heilig

german cancer research center
H指数:23
被引数:2,765

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Clinically actionable genomic and transcriptomic landscape of advanced neuroendocrine neoplasms

晚期神经内分泌肿瘤的临床可操作基因组学和转录组学景观

Med
IF11.8
2026-04-300
OAAI
Simon Kreutzfeldt; Leonidas Apostolidis; Małgorzata Oleś; Eva Krieghoff-Henning; Christoph E. Heilig; Christoph Heining; Andreas Mock; Maria-Veronica Teleanu; Barbara Hutter; Laura Gieldon; Barbara Klink; Katja Beck; Daniela Richter; Annika Baude-Müller; Eva Reisinger; Nils Hammer; Leila Kamkar; Katrin Pfütze; Christina Geörg; Mario Lamping
Multi-layered molecular profiling informs the diagnosis and targeted therapy of desmoplastic small round cell tumor

多层分子分析为硬化性小圆细胞肿瘤的诊断和靶向治疗提供信息

Nature Communications
IF15.7
2026-04-090
OA
Marcus Renner; Małgorzata Oleś; Nagarajan Paramasivam; Christoph E. Heilig; Annika Schneider; Caroline Modugno; Catherine Herremans; Jennifer Hüllein; Barbara Hutter; Cihan Erkut; Andreas Mock; Eva Krieghoff-Henning; Cecilia B. Jensen; Amirhossein Sakhteman; Matthew The; Tony Prinz; Panna Lajer; Annika Baude-Müller; Katja Beck; Bettina Beuthien-Baumann; Leonidas Apostolidis; Sebastian Bauer; Melanie Boerries; Christian H. Brandts; Damian T. Rieke; Thomas Kindler; Frederick Klauschen; Klaus Schulze-Osthoff; Richard F. Schlenk; Guy Berchem; Michael Allgäuer; Gunhild Mechtersheimer; Albrecht Stenzinger; Daniel B. Lipka; Matthias Schlesner; Bernhard Kuster; Arne Jahn; Evelin Schröck; Christoph Heining; Maria-Veronica Teleanu; Peter Horak; Simon Kreutzfeldt; Daniel Hübschmann; Wolfgang Hartmann; Hanno Glimm; Stefan Fröhling
The Knowledge Connector decision support system for multiomics-based precision oncology

基于多组学的精准肿瘤学知识连接器决策支持系统

Nature Communications
IF15.7
2026-01-190
OAAI
Daniel Hübschmann; Simon Kreutzfeldt; Benjamin Roth; Katrin Glocker; Janine Schoop; Lena Oeser; Steffen Hausmann; Christian Koch; Sebastian Uhrig; Jennifer Hüllein; Barbara Hutter; Martina Fröhlich; Christoph E. Heilig; Maria-Veronica Teleanu; Daniel B. Lipka; Irina A. Kerle; Annika Baude-Müller; Katja Beck; Christoph Heining; Hanno Glimm; Frank Ückert; Alexander Knurr; Stefan Fröhling; Peter Horak
Rationale and design of the PAMSARC (pasireotide as maintenance treatment with monthly deep intramuscular injection in SSTR2/3/ 5-expressing synovial sarcoma and desmoplastic small round cell tumor) multicenter phase 2 trial

PAMSARC（在表达SSTR2/3/5的滑膜肉瘤和弥漫性小圆细胞瘤中使用帕西瑞肽作为每月深部肌肉注射的维持治疗）多中心II期试验的原理与设计

CANCER TREATMENT AND RESEARCH COMMUNICATIONS
IF0
2025-09-010
OAAI
Heilig, Christoph E.; Heining, Christoph; Gnutzmann, Editha; Roldan, Sandra; Heiligenthal, Laura; Sparber-Sauer, Monika; Hahn, Dennis; Dirksen, Uta; Hamacher, Rainer; Florcken, Anne; Thorwarth, Anne; Deinzer, Christoph K. W.; Gaidzik, Verena I.; Pfaff, Elke; Hubschmann, Daniel; Arndt, Karin; Pfister, Stefan M.; Glimm, Hanno; Frohling, Stefan; Schlenk, Richard F.
CDK4/6 inhibition in advanced chordoma: final results of the NCT PMO-1601 trial

CDK4/6抑制剂在晚期软骨肉瘤中的应用：NCT PMO-1601试验的最终结果

ESMO Open
IF8.3
2025-07-070
OA
M.-V. Teleanu; C.E. Heilig; S. Pirmann; R. Hamacher; S. Bauer; V.I. Gaidzik; R. Mayer-Steinacker; J. Al-Sabah; S.S.L. Roldan Pinzon; H. Süße; A. Freitag; P. Horak; S. Kreutzfeldt; B. Hutter; J. Hüllein; O. Sedlaczek; B. Lehner; G. Egerer; D. Jäger; C. Müller-Tidow; R.F. Schlenk
Comprehensive genomic and transcriptomic analysis enables molecularly guided therapy options in peritoneal and pleural mesothelioma

全面的基因组学和转录组学分析能够实现针对腹膜和胸膜间皮瘤的分子引导治疗方案。

ESMO OPEN
IF8.3
2025-04-010
OAAI
Moehrmann, L.; Werner, M.; Oles, M.; Knol, L.; Arnold, J. S.; Mundt, T.; Paramasivam, N.; Richter, D.; Froehlich, M.; Hutter, B.; Huellein, J.; Jahn, A.; Scheffold, C.; Moehrmann, E. E.; Hanf, D.; Kreutzfeldt, S.; Heilig, C. E.; Teleanu, M. -, V; Lipka, D. B.; Beck, K.; Baude-Muelle, A.; Jelas, I.; Rieke, D. T.; Klotz, L., V; Shah, R.; Herold, T.; Boerries, M.; Illert, A. L.; Allgaeuer, M.; Stenzinger, A.; Kerle, I. A.; Horak, P.; Heining, C.; Schroeck, E.; Huebschmann, D.; Froehling, S.; Glimm, H.
Multi-omic profiling in cholangiocarcinoma to enable scientific advancement within the DKFZ/NCT/DKTK MASTER study

多组学分析在胆管癌中的应用，以推动DKFZ/NCT/DKTK MASTER研究中的科学进展

ANNALS OF ONCOLOGY
IF65.4
2024-09-010
PRE
Nichetti, F.; Korell, F.; Schwab, M.; Hoffmeister, P. K. M.; Huellein, J.; Uhrig, S.; Teleanu, M-V; Kreutzfeldt, S.; Horak, P.; Glimm, H.; Heining, C.; Rieke, D. T.; Kindler, T.; Huebschmann, D.; Springfeld, C.; Jenzer, M.; Heilig, C. E.; Froehling, S.; Koehler, B. C.
Inavolisib in cancers with activating PIK3CA mutations: Results from the CRAFT trial

Inavolisib在具有激活性PIK3CA突变的癌症中的研究：CRAFT试验的结果

ANNALS OF ONCOLOGY
IF65.4
2024-09-010
PRE
Heilig, C. E.; Teleanu, M-V.; Desuki, A.; Kindler, T.; Deschler, B.; Kunzmann, V.; von Bubnoff, N.; Illert, L.; Rieke, D. T.; Suesse, H.; Heiligenthal, L.; Kreutzfeldt, S.; Horak, P.; Steindorf, K.; Benner, A.; Huebschmann, D.; Schweigert, N.; Glimm, H.; Froehling, S.; Schlenk, R. F.
Randomized phase II study of trabectedin/olaparib compared to physician's choice in subjects with previously treated advanced or recurrent solid tumors harboring DNA repair deficiencies

随机对照II期研究，比较曲贝替定/奥拉帕利与医生选择方案在既往接受过治疗的、存在DNA修复缺陷的晚期或复发性实体瘤患者中的疗效。

ANNALS OF ONCOLOGY
IF65.4
2024-09-010
PRE
Schlenk, R. F.; Ruebsam, M.; Teleanu, M-V.; Richter, S.; Siveke, J. T.; Wagner, S.; Kopp, H-G.; Kindler, T.; Illert, L.; Golf, A. H-E.; Dorman, K.; Schreck, N.; Benner, A.; Suesse, H.; Freitag, A.; von Kalle, C.; Glimm, H.; Huebschmann, D.; Froehling, S.; Heilig, C. E.
Pasireotide as maintenance treatment in SSTR2/3/5-expressing synovial sarcoma and desmoplastic small round cell tumor: The PAMSARC study

帕希瑞otide作为SSTR2/3/5表达型滑膜肉瘤和硬化性小圆细胞瘤的维持治疗：PAMSARC研究

ANNALS OF ONCOLOGY
IF65.4
2024-09-010
PRE
Schlenk, R. F.; Heining, C.; Gnutzmann, E.; Roldan, S. S. L.; Heiligenthal, L.; Sauer, M. Sparber; Hahn, D. A.; Dirksen, U.; Hamacher, R. W.; Floercken, A.; Thorwarth, A.; Deinzer, C.; Gaidzik, V.; van Tilburg, C. M.; Huebschmann, D.; Arndt, K.; Pfister, S. M.; Glimm, H.; Froehling, S.; Heilig, C. E.
Fibroblast Activation Protein α-Directed Imaging and Therapy of Solitary Fibrous Tumor

成纤维细胞活化蛋白 α 定向显像与孤立性纤维瘤的治疗

JOURNAL OF NUCLEAR MEDICINE
IF9.1
2024-01-043
OA
Hamacher, Rainer; Pabst, Kim M.; Cheung, Phyllis F.; Heilig, Christoph E.; Hullein, Jennifer; Liffers, Sven-Thorsten; Borchert, Sabrina; Costa, Pedro Fragoso; Schaarschmidt, Benedikt M.; Kessler, Lukas; Miera, Monika A.; Droste, Margret; Akbulut, Merve; Falkenhorst, Johanna; Zarrad, Fadi; Kostbade, Karina; Mavroeidi, Ilektra A.; Glimm, Hanno; Umutlu, Lale; Schuler, Martin; Hubschmann, Daniel; Bauer, Sebastian; Frohling, Stefan; Herrmann, Ken; Siveke, Jens T.; Schildhaus, Hans-Ulrich; Fendler, Wolfgang P.
Multi-omic and functional analysis for classification and treatment of sarcomas with FUS-TFCP2 or EWSR1-TFCP2 fusions

基于FUS-TFCP2或EWSR1-TFCP2融合基因的肉瘤分类与治疗的多组学及功能分析

NATURE COMMUNICATIONS
IF15.7
2024-01-023
OAAI
Schoepf, Julia; Uhrig, Sebastian; Heilig, Christoph E.; Lee, Kwang-Seok; Walther, Tatjana; Carazzato, Alexander; Dobberkau, Anna Maria; Weichenhan, Dieter; Plass, Christoph; Hartmann, Mark; Diwan, Gaurav D.; Carrero, Zunamys, I; Ball, Claudia R.; Hohl, Tobias; Kindler, Thomas; Rudolph-Haehnel, Patricia; Helm, Dominic; Schneider, Martin; Nilsson, Anna; Ora, Ingrid; Imle, Roland; Banito, Ana; Russell, Robert B.; Jones, Barbara C.; Lipka, Daniel B.; Glimm, Hanno; Huebschmann, Daniel; Hartmann, Wolfgang; Froehling, Stefan; Scholl, Claudia
Etiology-independent activation of the LTβ-LTβR-RELB axis drives aggressiveness and predicts poor prognosis in Hepatocellular carcinoma
HEPATOLOGY
IF15.8
2023-11-023
PRE
Scherr, Anna-Lena; Nader, Luisa; Xu, Kaiyu; Elssner, Christin; Ridder, Dirk A.; Nichetti, Federico; Mastel, Manuel; Fritzsche, Sarah; Kelmendi, Eblina; Schmitt, Nathalie; Hoffmeister-Wittmann, Paula; Weiler, Sofia M. E.; Korell, Felix; Albrecht, Thomas; Schwab, Maximilian; Isele, Hanna; Kessler, Annika; Huellein, Jennifer; Seretny, Agnieszka; Ye, Liangtao; Urbanik, Toni; Welte, Stefan; Leblond, Anne-Laure; Heilig, Christoph E.; Rahbari, Mohammad; Ali, Adnan; Gallage, Suchira; Lenoir, Benedicte; Wilhelm, Nina; Gaertner, Ulrike; Ogrodnik, Simon J.; Springfeld, Christoph; Tschaharganeh, Darjus; Froehling, Stefan; Longerich, Thomas; Schulze-Bergkamen, Henning; Jaeger, Dirk; Brandl, Lydia; Schirmacher, Peter; Straub, Beate K.; Weber, Achim; De Toni, Enrico N.; Goeppert, Benjamin; Heikenwalder, Mathias; Jackstadt, Rene; Roessler, Stephanie; Breuhahn, Kai; Koehler, Bruno C.
NCT/DKFZ MASTER handbook of interpreting whole-genome, transcriptome, and methylome data for precision oncology
NPJ PRECISION ONCOLOGY
IF8
2023-10-267
OAAI
Mock, Andreas; Teleanu, Maria-Veronica; Kreutzfeldt, Simon; Heilig, Christoph E.; Huellein, Jennifer; Moehrmann, Lino; Jahn, Arne; Hanf, Dorothea; Kerle, Irina A.; Singh, Hans Martin; Hutter, Barbara; Uhrig, Sebastian; Froehlich, Martina; Neumann, Olaf; Hartig, Andreas; Brueckmann, Sascha; Hirsch, Steffen; Grund, Kerstin; Dikow, Nicola; Lipka, Daniel B.; Renner, Marcus; Bhatti, Irfan Ahmed; Apostolidis, Leonidas; Schlenk, Richard F.; Schaaf, Christian P.; Stenzinger, Albrecht; Schroeck, Evelin; Huebschmann, Daniel; Heining, Christoph; Horak, Peter; Glimm, Hanno; Froehling, Stefan

研究方向

暂未获取到该数据
H
Hanno Glimm
H 指数:54论文数:401被引数:1.3万
S
Stefan Fröhling
H 指数:80论文数:627被引数:3.2万
P
Peter Horak
H 指数:37论文数:236被引数:5,484
S
Simon Kreutzfeldt
H 指数:20论文数:95被引数:2,330
C
Christoph Heining
H 指数:26论文数:150被引数:3,139
A
Albrecht Stenzinger
H 指数:79论文数:969被引数:2.9万
B
Benedikt Brors
H 指数:100论文数:789被引数:5.2万
B
Barbara Hutter
H 指数:58论文数:241被引数:3.5万
S
Sebastian Uhrig
H 指数:27论文数:116被引数:3,114
D
Daniel Hübschmann
H 指数:52论文数:265被引数:2.2万