Bruce A. Vallance - Publications, H-index & Citations

Bruce A. Vallance

University of British Columbia

77H指数

326论文数

2.0W被引数

收录论文 128

发表时间

The gut microbiota in malnutrition 营养不良中的肠道菌群

Nature Reviews Microbiology

IF103.3

2026-08-27

PREAI

Paula T. Littlejohn; Ravi Holani; Bruce A. Vallance; B. Brett Finlay

In mouse and in vitro models, bowel preparation promotes pathogen colonization, translocation, and exacerbation of inflammation 在鼠类和体外模型中，肠道准备促进病原体定植、易位和炎症加剧。

Cell Reports Medicine

IF10.6

2025-12-22

OAAI

Charlotte A. Clayton; Imogen Porter; Brian D. Deng; Giselle McCallum; Apsara Srinivas; Claire Sie; Jerry Y. He; Alexander D. Pei; Dominique Tertigas; Deanna M. Pepin; Touran Fardeen; Katharine M. Ng; Sidhartha R. Sinha; Michael G. Surette; Bruce A. Vallance; Carolina Tropini

TYK2 inhibition enhances Treg differentiation and function while preventing Th1 and Th17 differentiation TYK2抑制增强了Treg的分化和功能，同时阻止了Th1和Th17的分化和发育。

Cell Reports Medicine

IF10.6

2025-08-19

OAAI

Karoliina Tuomela; Rosa V. Garcia; Dominic A. Boardman; Pedram Tavakoli; Maria Ancheta-Schmit; Ho Pan Sham; Lihong Cheng; Mary Struthers; Brian Bressler; Bruce A. Vallance; Qihong Zhao; Megan K. Levings

Fasting elicits gut microbiome signature changes that extend to type 1 diabetes patients 禁食会引起肠道微生物组特征的变化，这些变化延伸至1型糖尿病患者。

Frontiers in Endocrinology

IF4.6

2025-08-13

OAAI

Franziska A. Graef; Bettina Berger; Lina S. Bahr; Rainer Stange; Andreas Michalsen; Friedemann Paul; Bruce A. Vallance; Kevan Jacobson

Nociceptor neurons suppress alveolar macrophage-induced Siglec-F+ neutrophil-mediated inflammation to protect against pulmonary fibrosis 痛觉神经元抑制肺泡巨噬细胞诱导的Siglec-F+中性粒细胞介导的炎症，以防止肺纤维化。

Immunity

IF26.3

2025-05-30

PREAI

Carlos H. Hiroki; Mortaza F. Hassanabad; Manon Defaye; Nicole Sarden; Alexandria Bartlett; Raquel Farias; Angela P. Nguyen; Idaira M. Guerrero-Fonseca; Grace Yoon; Luke Brown; Caixia Ma; Hyungjun Yang; Darrel Belke; Ali Fatehi Hassanabad; Christopher McCoy; Nicole L. Rosin; Dennis J. Orton; Paul W.M. Fedak; Bruce A. Vallance; Hongbing Yu; Kevan Jacobson; Nargis Khan; Christophe Altier; Margaret M. Kelly; Bryan G. Yipp

Defining enteric bacterial pathogenesis using organoids: Citrobacter rodentium uses EspC, an atypical mucinolytic protease, to penetrate mouse colonic mucus 利用类器官定义肠道细菌致病性：Citrobacter rodentium利用EspC，一种非典型的粘液溶解蛋白酶，来穿透小鼠结肠粘液。

GUT MICROBES

IF11

2025-05-05

OAAI

Yan Chen; Ashley Gilliland; Qiaochu Liang; Xiao Han; Hyungjun Yang; Jocelyn Chan; Dominique Lévesque; Kyung-Mee Moon; Parandis Daneshgar; François-Michel Boisvert; Leonard Foster; Wesley F. Zandberg; Kirk Bergstrom; Hong B. Yu; Bruce A. Vallance

Crosstalk with infant-derived Th17 cells, as well as exposure to IL-22 promotes maturation of intestinal epithelial cells in an enteroid model 与婴儿来源的Th17细胞的相互作用，以及IL-22的暴露，在类器官模型中促进了肠道上皮细胞的成熟。

FRONTIERS IN IMMUNOLOGY

IF5.9

2025-05-01

OAAI

Sharafian, Zohreh; Littlejohn, Paula T.; Michalski, Christina; Sousa, James A.; Cheung, Janelle; Hill, Mariana; Piper, Hannah; Jacobson, Kevan; Lavoie, Pascal M.; Allaire, Joannie M.; Vallance, Bruce A.

The gut-skin axis: a bi-directional, microbiota-driven relationship with therapeutic potential 肠道-皮肤轴：一种双向的、微生物群驱动的具有治疗潜力的关系

GUT MICROBES

IF11

2025-03-06

OAAI

Maira Jimenez-Sanchez; Larissa S. Celiberto; Hyungjun Yang; Ho Pan Sham; Bruce A. Vallance

MUC17 is an essential small intestinal glycocalyx component that is disrupted in Crohn's disease MUC17是一种重要的小肠糖萼成分，在克罗恩病中被破坏

JCI INSIGHT

IF6.1

2024-12-19

OAAI

Layunta, Elena; Javerfelt, Sofia; van de Koolwijk, Fleur C.; Sivertsson, Molly; Dolan, Brendan; Arike, Liisa; Thulin, Sara I. M.; Vallance, Bruce A.; Pelaseyed, Thaher

Inflammasome activation links enteric Salmonella Typhimurium infection to a rapid, cytokine-dependent increase in intestinal mucin release

GUT MICROBES

IF11

2024-10-20

OAAI

Han, Xiao; Allaire, Joannie M.; Crowley, Shauna M.; Chan, Jocelyn J.; Lau, Kelly; Zhang, Conghao; Hirota, Simon A.; Bergstrom, Kirk; Knodler, Leigh A.; Vallance, Bruce A.

Pathobionts in Inflammatory Bowel Disease: Origins, Underlying Mechanisms, and Implications for Clinical Care 炎症性肠病的病因: 起源，潜在机制和对临床护理的影响

GASTROENTEROLOGY

IF25.1

2024-01-01

OAAI

Gilliland, Ashley; Chan, Jocelyn J.; De Wolfe, Travis J.; Yang, Hyungjun; Vallance, Bruce A.

Outcomes Following Acute Severe Colitis at Initial Presentation: A Multi-centre, Prospective, Paediatric Cohort Study

JOURNAL OF CROHNS & COLITIS

IF8.7

2023-08-21

OAAI

Dhaliwal, Jasbir; Tertigas, Dominique; Carman, Nicholas; Lawrence, Sally; Debruyn, Jennifer C.; Wine, Eytan; Church, Peter C.; Huynh, Hien Q.; Rashid, Mohsin; El-Matary, Wael; Deslandres, Colette; Critch, Jeffrey; Ricciuto, Amanda; Carroll, Matthew W.; Benchimol, Eric, I; Muise, Aleixo; Jacobson, Kevan; Otley, Anthony R.; Vallance, Bruce; Mack, David R.; Walters, Thomas D.; Surette, Michael G.; Griffiths, Anne M.

Sialic acid plays a pivotal role in licensing Citrobacter rodentium's transition from the intestinal lumen to a mucosal adherent niche 唾液酸在许可柠檬酸杆菌从肠腔到粘膜粘附小生境的过渡中起着关键作用

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-07-03

OAAI

Liang, Qiaochu; Ma, Caixia; Crowley, Shauna M.; Allaire, Joannie M.; Han, Xiao; Chong, Raymond W. W.; Packer, Nicolle H.; Yu, Hong Bing; Vallance, Bruce A.

ERdj5 protects goblet cells from endoplasmic reticulum stress-mediated apoptosis under inflammatory conditions

EXPERIMENTAL AND MOLECULAR MEDICINE

IF12.9

2023-02-09

OAAI

Jeong, Hyunjin; Hong, Eun-Hye; Ahn, Jae-Hee; Cho, Jaewon; Jeong, Jae-Hyeon; Kim, Chae-Won; Yoon, Byung-Il; Koo, Ja Hyun; Park, Yun-Yong; Yang, Yoon Mee; Iwawaki, Takao; Vallance, Bruce A.; Chang, Sun-Young; Ko, Hyun-Jeong

Highly Sensitive, Flow Cytometry-Based Measurement of Intestinal Permeability in Models of Experimental Colitis

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY

IF7.4

2023-01-01

OAAI

Tsai, Kevin; Ma, Caixia; Han, Xiao; Allaire, Joannie; Lunken, Genelle R.; Crowley, Shauna M.; Yu, Hongbing; Jacobson, Kevan; Xia, Lijun; Priatel, John J.; Vallance, Bruce A.

Autism Risk and Perinatal Antibiotic Use

PEDIATRICS

IF6.4

2022-08-26

PREAI

Nitschke, Amanda S.; Karim, Jalisa L.; Vallance, Bruce A.; Bickford, Celeste; Ip, Angie; Lanphear, Nancy; Lanphear, Bruce; Weikum, Whitney; Oberlander, Tim F.; Hanley, Gillian E.

Gut-derived bacterial flagellin induces beta-cell inflammation and dysfunction 肠源性细菌鞭毛蛋白诱导 β 细胞炎症和功能障碍

GUT MICROBES

IF11

2022-08-19

OAAI

Scheithauer, Torsten P. M.; Herrema, Hilde; Yu, Hongbing; Bakker, Guido J.; Winkelmeijer, Maaike; Soukhatcheva, Galina; Dai, Derek; Ma, Caixia; Havik, Stefan R.; Balvers, Manon; Davids, Mark; Meijnikman, Abraham S.; Aydin, Omrum; Van den Born, Bert-Jan H.; Besselink, Marc G.; Busch, Olivier R.; de Brauw, Maurits; van de Laar, Arnold; Belzer, Clara; Stahl, Martin; de Vos, Willem M.; Vallance, Bruce A.; Nieuwdorp, Max; Verchere, C. Bruce; van Raalte, Daniel H.

A nonredundant role for T cell-derived interleukin 22 in antibacterial defense of colonic crypts

IMMUNITY

IF26.3

2022-03-01

OAAI

Zindl, Carlene L.; Witte, Steven J.; Laufer, Vincent A.; Gao, Min; Yue, Zongliang; Janowski, Karen M.; Cai, Baiyi; Frey, Blake F.; Silberger, Daniel J.; Harbour, Stacey N.; Singer, Jeffrey R.; Turner, Henrietta; Lund, Frances E.; Vallance, Bruce A.; Rosenberg, Alexander F.; Schoeb, Trenton R.; Chen, Jake Y.; Hatton, Robin D.; Weaver, Casey T.

Vasoactive intestinal peptide promotes host defense against enteric pathogens by modulating the recruitment of group 3 innate lymphoid cells

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-10-08

OAAI

Yu, Hong Bing; Yang, Hyungjun; Allaire, Joannie M.; Ma, Caixia; Graef, Franziska A.; Mortha, Arthur; Liang, Qiaochu; Bosman, Else S.; Reid, Gregor S.; Waschek, James A.; Osborne, Lisa C.; Sokol, Harry; Vallance, Bruce A.; Jacobson, Kevan

What's for dinner? How Citrobacter rodentium's metabolism helps it thrive in the competitive gut

CURRENT OPINION IN MICROBIOLOGY

IF7.5

2021-10-01

PREAI

Liang, Qiaochu; Vallance, Bruce A.

研究方向