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C

Claudio Isella

istituto nazionale oncologico candiolo
H指数:35
被引数:5,379

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Circulating tumor DNA-guided de-escalation or escalation of adjuvant therapy in high-risk stage II and stage III colon cancer: the phase 2 PEGASUS trial

循环肿瘤DNA指导的高风险II期和III期结肠癌辅助治疗降级或升级：PEGASUS II期试验

Nature Cancer
IF28.5
2026-09-140
OAAI
Silvia Marsoni; Clara Montagut; Filippo Pietrantonio; Andrea Sartore-Bianchi; Luca Lazzari; Francesca Bergamo; Maria Giulia Zampino; Noelia Tarazona; Mario Mandalà; Stefano Tamberi; Elena Elez; Cristina Santos Vivas; Paolo Luraghi; Michele Prisciandaro; Federica Tosi; Davide Ciardiello; Joana Vidal; Victor Seguì; Michele Palazzo; Giulia Maddalena; Katia Bencardino; Ida Taglialatela; Marta Guix; Eliana Rulli; Valentina Vettore; Federica Morano; Claudio Isella; Giovanni Crisafulli; Giorgio Patelli; Enzo Medico; Alberto Bardelli; Andrés Cervantes; Valter Torri; Josep Tabernero; Salvatore Siena; Sara Lonardi
The paracrine Ephrin A4/BMP4 feed-forward loop sustains a tumor–CAF vicious cycle in osteosarcoma

旁分泌Ephrin A4/BMP4正反馈回路维持骨肉瘤中肿瘤–CAF恶性循环

Cell Communication and Signaling
IF8.9
2026-09-030
OA
Giorgia Giordano; Cristina Tucciarello; Erika Gucciardo; Jørgen Wesche; Leonardo A. Meza-Zepeda; Ola Myklebost; Elisa Tirtei; Alessandra Merlini; Simona Comparato; Santina Cutrupi; Lorenzo D’Ambrosio; Franca Fagioli; Dario Sangiolo; Claudio Isella; Anna Sapino; Caterina Marchiò; Giovanni Grignani; Ymera Pignochino
Concurrent RB1 and P53 pathway disruption predisposes to the development of a primitive neuronal component in high-grade gliomas depending on MYC-driven EBF3 transcription

RB1和P53通路的同时性破坏会促使高级别胶质瘤中依赖MYC驱动的EBF3转录的原始神经元成分的发展。

ACTA NEUROPATHOLOGICA
IF9.3
2025-01-160
PRE
Pagani, F; Orzan, F; Lago, S; De Bacco, F; Prelli, M; Cominelli, M; Somenza, E; Gryzik, M; Balzarini, P; Ceresa, D; Marubbi, D; Isella, C; Crisafulli, G; Poli, M; Malatesta, P; Galli, R; Ronca, R; Zippo, A; Boccaccio, C; Poliani, PL
Transcriptional features of stage IIT4N0/III colon cancer associated with residual disease and ctDNA status after surgery in the PEGASUS trial

PEGASUS试验中，与术后残留病灶及ctDNA状态相关的II期T4N0/III期结肠癌的转录特征

ANNALS OF ONCOLOGY
IF65.4
2024-09-010
PRE
Medico, E.; Buffa, F. M.; Isella, C.; Skenderi, G.; Lazzari, L.; Prisciandaro, M.; Lonardi, S.; Tarazona Llavero, N.; Montagut Viladot, C.; Bianchi, A. Sartore; Zampino, M. G.; Elez Fernandez, M. E.; Santos Vivas, C.; Mandala, M.; Tamberi, S.; Calon, A.; Cervantes, A.; Siena, S.; Bardelli, A.; Marsoni, S.
Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer (Vol 56, pg 458, 2024)
NATURE GENETICS
IF31.8
2024-06-031
OAAI
Malla, Sudhir B.; Byrne, Ryan M.; Lafarge, Maxime W.; Corry, Shania M.; Fisher, Natalie C.; Tsantoulis, Petros K.; Mills, Megan L.; Ridgway, Rachel A.; Lannagan, Tamsin R. M.; Najumudeen, Arafath K.; Gilroy, Kathryn L.; Amirkhah, Raheleh; Maguire, Sarah L.; Mulholland, Eoghan J.; Belnoue-Davis, Hayley L.; Grassi, Elena; Viviani, Marco; Rogan, Emily; Redmond, Keara L.; Sakhnevych, Svetlana; McCooey, Aoife J.; Bull, Courtney; Hoey, Emily; Sinevici, Nicoleta; Hall, Holly; Ahmaderaghi, Baharak; Domingo, Enric; Blake, Andrew; Richman, Susan D.; Isella, Claudio; Miller, Crispin; Bertotti, Andrea; Trusolino, Livio; Loughrey, Maurice B.; Kerr, Emma M.; Tejpar, Sabine; Maughan, Timothy S.; Lawler, Mark; Campbell, Andrew D.; Leedham, Simon J.; Koelzer, Viktor H.; Sansom, Owen J.; Dunne, Philip D.
Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer
NATURE GENETICS
IF31.8
2024-02-1310
OAAI
Malla, Sudhir B.; Byrne, Ryan M.; Lafarge, Maxime W.; Corry, Shania M.; Fisher, Natalie C.; Tsantoulis, Petros K.; Mills, Megan L.; Ridgway, Rachel A.; Lannagan, Tamsin R. M.; Najumudeen, Arafath K.; Gilroy, Kathryn L.; Amirkhah, Raheleh; Maguire, Sarah L.; Mulholland, Eoghan J.; Belnoue-Davis, Hayley L.; Grassi, Elena; Viviani, Marco; Rogan, Emily; Redmond, Keara L.; Sakhnevych, Svetlana; Mccooey, Aoife J.; Bull, Courtney; Hoey, Emily; Sinevici, Nicoleta; Hall, Holly; Ahmaderaghi, Baharak; Domingo, Enric; Blake, Andrew; Richman, Susan D.; Isella, Claudio; Miller, Crispin; Bertotti, Andrea; Trusolino, Livio; Loughrey, Maurice B.; Kerr, Emma M.; Tejpar, Sabine; Maughan, Timothy S.; Lawler, Mark; Campbell, Andrew D.; Leedham, Simon J.; Koelzer, Viktor H.; Sansom, Owen J.; Dunne, Philip D.
Coexisting cancer stem cells with heterogeneous gene amplifications, transcriptional profiles, and malignancy are isolated from single glioblastomas
CELL REPORTS
IF6.9
2023-08-015
OA
De Bacco, Francesca; Orzan, Francesca; Crisafulli, Giovanni; Prelli, Marta; Isella, Claudio; Casanova, Elena; Albano, Raffaella; Reato, Gigliola; Erriquez, Jessica; D'Ambrosio, Antonio; Panero, Mara; Dall'Aglio, Carmine; Casorzo, Laura; Cominelli, Manuela; Pagani, Francesca; Melcarne, Antonio; Zeppa, Pietro; Altieri, Roberto; Morra, Isabella; Cassoni, Paola; Garbossa, Diego; Cassisa, Anna; Bartolini, Alice; Pellegatta, Serena; Comoglio, Paolo M.; Finocchiaro, Paolo M. Gaetano; Poliani, Pietro L.; Boccaccio, Carla
DNA damage response and repair genes in advanced bone and soft tissue sarcomas: An 8-gene signature as a candidate predictive biomarker of response to trabectedin and olaparib combination

晚期骨和软组织肉瘤中的DNA损伤反应和修复基因: 8基因签名作为对小梁丁和奥拉帕尼组合反应的候选预测生物标志物

FRONTIERS IN ONCOLOGY
IF3.3
2022-08-3010
OAAI
Merlini, Alessandra; Centomo, Maria Laura; Ferrero, Giulio; Chiabotto, Giulia; Miglio, Umberto; Berrino, Enrico; Giordano, Giorgia; Brusco, Silvia; Pisacane, Alberto; Maldi, Elena; Sarotto, Ivana; Capozzi, Federica; Lano, Cristina; Isella, Claudio; Crisafulli, Giovanni; Aglietta, Massimo; Dei Tos, Angelo Paolo; Sbaraglia, Marta; Sangiolo, Dario; D'Ambrosio, Lorenzo; Bardelli, Alberto; Pignochino, Ymera; Grignani, Giovanni
A non-dividing cell population with high pyruvate dehydrogenase kinase activity regulates metabolic heterogeneity and tumorigenesis in the intestine
NATURE COMMUNICATIONS
IF15.7
2022-03-2125
OAAI
Sebastian, Carlos; Ferrer, Christina; Serra, Maria; Choi, Jee-Eun; Ducano, Nadia; Mira, Alessia; Shah, Manasvi S.; Stopka, Sylwia A.; Perciaccante, Andrew J.; Isella, Claudio; Moya-Rull, Daniel; Vara-Messler, Marianela; Giordano, Silvia; Maldi, Elena; Desai, Niyati; Capen, Diane E.; Medico, Enzo; Cetinbas, Murat; Sadreyev, Ruslan, I; Brown, Dennis; Rivera, Miguel N.; Sapino, Anna; Breault, David T.; Agar, Nathalie Y. R.; Mostoslavsky, Raul
The EurOPDX Data Portal: an open platform for patient-derived cancer xenograft data sharing and visualization
BMC GENOMICS
IF3.7
2022-02-2210
OAAI
Dudova, Zdenka; Conte, Nathalie; Mason, Jeremy; Stuchlik, Dalibor; Pesa, Radim; Halmagyi, Csaba; Perova, Zinaida; Mosaku, Abayomi; Thorne, Ross; Follette, Alex; Pivarc, Luboslav; Sasinka, Radim; Usman, Muhammad; Neuhauser, Steven; Begley, Dale A.; Krupke, Debra M.; Frassa, Massimiliano; Fiori, Alessandro; Corsi, Riccardo; Vezzadini, Luca; Isella, Claudio; Bertotti, Andrea; Bult, Carol; Parkinson, Helen; Medico, Enzo; Meehan, Terrence; Krenek, Ales
Molecular Subtyping Combined with Biological Pathway Analyses to Study Regorafenib Response in Clinically Relevant Mouse Models of Colorectal Cancer
CLINICAL CANCER RESEARCH
IF10.2
2021-08-239
OA
Lafferty, Adam; O'Farrell, Alice C.; Migliardi, Giorgia; Khemka, Niraj; Lindner, Andreas U.; Sassi, Francesco; Zanella, Eugenia R.; Salvucci, Manuela; Vanderheyden, Evy; Modave, Elodie; Boeckx, Bram; Halang, Luise; Betge, Johannes; Ebert, Matthias P. A.; Dicker, Patrick; Argiles, Guillem; Tabernero, Josep; Dienstmann, Rodrigo; Medico, Enzo; Lambrechts, Diether; Bertotti, Andrea; Isella, Claudio; Trusolino, Livio; Prehn, Jochen H. M.; Byrne, Annette T.
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts (vol 53, pg 86, 2021)

在患者来源的癌症异种移植物的植入和传代过程中保留拷贝数谱 (第53卷，第86页，2021页)

NATURE GENETICS
IF31.8
2021-02-194
OAAI
Woo, Xing Yi; Giordano, Jessica; Srivastava, Anuj; Zhao, Zi-Ming; Lloyd, Michael W.; de Bruijn, Roebi; Suh, Yun-Suhk; Patidar, Rajesh; Chen, Li; Scherer, Sandra; Bailey, Matthew H.; Yang, Chieh-Hsiang; Cortes-Sanchez, Emilio; Xi, Yuanxin; Wang, Jing; Wickramasinghe, Jayamanna; Kossenkov, Andrew V.; Rebecca, Vito W.; Sun, Hua; Mashl, R. Jay; Davies, Sherri R.; Jeon, Ryan; Frech, Christian; Randjelovic, Jelena; Rosains, Jacqueline; Galimi, Francesco; Bertotti, Andrea; Lafferty, Adam; O'Farrell, Alice C.; Modave, Elodie; Lambrechts, Diether; ter Brugge, Petra; Serra, Violeta; Marangoni, Elisabetta; El Botty, Rania; Kim, Hyunsoo; Kim, Jong-Il; Yang, Han-Kwang; Lee, Charles; Dean, Dennis A., II; Davis-Dusenbery, Brandi; Evrard, Yvonne A.; Doroshow, James H.; Welm, Alana L.; Welm, Bryan E.; Lewis, Michael T.; Fang, Bingliang; Roth, Jack A.; Meric-Bernstam, Funda; Herlyn, Meenhard; Davies, Michael A.; Ding, Li; Li, Shunqiang; Govindan, Ramaswamy; Isella, Claudio; Moscow, Jeffrey A.; Trusolino, Livio; Byrne, Annette T.; Jonkers, Jos; Bult, Carol J.; Medico, Enzo; Chuang, Jeffrey H.
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts

在患者来源的癌症异种移植物的植入和传代过程中保留拷贝数谱

NATURE GENETICS
IF31.8
2021-01-07125
OAAI
Woo, Xing Yi; Giordano, Jessica; Srivastava, Anuj; Zhao, Zi-Ming; Lloyd, Michael W.; de Bruijn, Roebi; Suh, Yun-Suhk; Patidar, Rajesh; Chen, Li; Scherer, Sandra; Bailey, Matthew H.; Yang, Chieh-Hsiang; Cortes-Sanchez, Emilio; Xi, Yuanxin; Wang, Jing; Wickramasinghe, Jayamanna; Kossenkov, Andrew V.; Rebecca, Vito W.; Sun, Hua; Mashl, R. Jay; Davies, Sherri R.; Jeon, Ryan; Frech, Christian; Randjelovic, Jelena; Rosains, Jacqueline; Galimi, Francesco; Bertotti, Andrea; Lafferty, Adam; O'Farrell, Alice C.; Modave, Elodie; Lambrechts, Diether; ter Brugge, Petra; Serra, Violeta; Marangoni, Elisabetta; El Botty, Rania; Kim, Hyunsoo; Kim, Jong-Il; Yang, Han-Kwang; Lee, Charles; Dean, Dennis A., II; Davis-Dusenbery, Brandi; Evrard, Yvonne A.; Doroshow, James H.; Welm, Alana L.; Welm, Bryan E.; Lewis, Michael T.; Fang, Bingliang; Roth, Jack A.; Meric-Bernstam, Funda; Herlyn, Meenhard; Davies, Michael A.; Ding, Li; Li, Shunqiang; Govindan, Ramaswamy; Isella, Claudio; Moscow, Jeffrey A.; Trusolino, Livio; Byrne, Annette T.; Jonkers, Jos; Bult, Carol J.; Medico, Enzo; Chuang, Jeffrey H.

研究方向

暂未获取到该数据
E
Enzo Médico
H 指数:55论文数:493被引数:1.4万
A
Andrea Bertotti
H 指数:49论文数:532被引数:1.4万
L
Livio Trusolino
H 指数:70论文数:622被引数:2.2万
A
Alberto Bardelli
H 指数:114论文数:928被引数:7.2万
C
Consalvo Petti
H 指数:14论文数:61被引数:2,420
F
Federica Di Nicolantonio
H 指数:63论文数:512被引数:2.6万
F
Francesco Galimi
H 指数:30论文数:134被引数:5,483
A
Anna Sapino
H 指数:74论文数:707被引数:2.0万
P
Paolo M. Comoglio
H 指数:116论文数:751被引数:4.5万
F
Francesco Sassi
H 指数:37论文数:357被引数:7,976